Published in J Invest Dermatol on March 15, 2007
Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses. Nat Immunol (2010) 4.34
Metalloproteinases and their inhibitors: regulators of wound healing. Int J Biochem Cell Biol (2007) 2.65
Prognostic impact of CXCL16 and CXCR6 in non-small cell lung cancer: combined high CXCL16 expression in tumor stroma and cancer cells yields improved survival. BMC Cancer (2015) 1.48
Species specificity of ADAM10 and ADAM17 proteins in interleukin-6 (IL-6) trans-signaling and novel role of ADAM10 in inducible IL-6 receptor shedding. J Biol Chem (2011) 1.29
A disintegrin and metalloproteinase 17 (ADAM17) mediates inflammation-induced shedding of syndecan-1 and -4 by lung epithelial cells. J Biol Chem (2009) 1.22
The chemokine CXCL16 is highly and constitutively expressed by human bronchial epithelial cells. Exp Lung Res (2009) 1.12
Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia. Am J Physiol Lung Cell Mol Physiol (2009) 1.06
Shedding of collagen XVII/BP180 in skin depends on both ADAM10 and ADAM9. J Biol Chem (2009) 1.02
Proteases and sFlt-1 release in the human placenta. Placenta (2010) 1.00
CXCL16 is expressed in podocytes and acts as a scavenger receptor for oxidized low-density lipoprotein. Am J Pathol (2009) 0.92
Homocysteine up-regulates vascular transmembrane chemokine CXCL16 and induces CXCR6+ lymphocyte recruitment in vitro and in vivo. J Cell Mol Med (2008) 0.85
ADAM10 is the major sheddase responsible for the release of membrane-associated meprin A. J Biol Chem (2014) 0.83
Expression analysis and clinical significance of CXCL16/CXCR6 in patients with bladder cancer. Oncol Lett (2012) 0.82
Overexpression of CXCL16 in lesional psoriatic skin. Dermatoendocrinol (2009) 0.79
The human cutaneous chemokine system. Front Immunol (2011) 0.79
Equine Arteritis Virus Uses Equine CXCL16 as an Entry Receptor. J Virol (2016) 0.77
Fine Tuning Cell Migration by a Disintegrin and Metalloproteinases. Mediators Inflamm (2017) 0.75
The Roles of ADAMs Family Proteinases in Skin Diseases. Enzyme Res (2011) 0.75
Elevated levels of serum sCXCL16 in systemic lupus erythematosus; potential involvement in cutaneous and renal manifestations. Clin Rheumatol (2014) 0.75
Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging. Int J Mol Sci (2017) 0.75
ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses. J Immunol (2017) 0.75
ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocation. Proc Natl Acad Sci U S A (2005) 3.57
The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion. Blood (2003) 3.51
Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death. Oncogene (2003) 2.96
ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion and beta-catenin nuclear signalling. EMBO J (2005) 2.95
The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart. Proc Natl Acad Sci U S A (2003) 2.53
Insights into sick sinus syndrome from an inducible mouse model. Cardiovasc Res (2010) 2.27
Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta. Cancer Res (2004) 2.19
The transmembrane CXC-chemokine ligand 16 is induced by IFN-gamma and TNF-alpha and shed by the activity of the disintegrin-like metalloproteinase ADAM10. J Immunol (2004) 2.19
The monocarboxylate transporter 8 linked to human psychomotor retardation is highly expressed in thyroid hormone-sensitive neuron populations. Endocrinology (2005) 2.14
HCN4 provides a 'depolarization reserve' and is not required for heart rate acceleration in mice. EMBO J (2007) 2.13
Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE). J Biol Chem (2003) 2.05
Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell surface molecules. Comb Chem High Throughput Screen (2005) 1.99
A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44. Biochem J (2006) 1.92
ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23. Nat Immunol (2006) 1.83
Abnormal thyroid hormone metabolism in mice lacking the monocarboxylate transporter 8. J Clin Invest (2007) 1.80
Identification of a novel proinflammatory human skin-homing Vγ9Vδ2 T cell subset with a potential role in psoriasis. J Immunol (2011) 1.79
Antagonistic roles of full-length N-cadherin and its soluble BMP cleavage product in neural crest delamination. Development (2006) 1.72
Experimental extracorporeal photopheresis inhibits the sensitization and effector phases of contact hypersensitivity via two mechanisms: generation of IL-10 and induction of regulatory T cells. J Immunol (2008) 1.69
Chemokine receptor CXCR6-dependent hepatic NK T Cell accumulation promotes inflammation and liver fibrosis. J Immunol (2013) 1.67
ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin. Circ Res (2008) 1.66
Tumor-associated MICA is shed by ADAM proteases. Cancer Res (2008) 1.64
Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels. J Biol Chem (2003) 1.63
In vivo structure/function and expression analysis of the CX3C chemokine fractalkine. Blood (2011) 1.63
The good, the bad and the ugly substrates for ADAM10 and ADAM17 in brain pathology, inflammation and cancer. Semin Cell Dev Biol (2008) 1.60
Production of endogenous antibiotics in articular cartilage. Arthritis Rheum (2004) 1.55
Intravenous infusion of syngeneic apoptotic cells by photopheresis induces antigen-specific regulatory T cells. J Immunol (2005) 1.49
Importance of CXC chemokine receptor 2 in the homing of human peripheral blood endothelial progenitor cells to sites of arterial injury. Circ Res (2007) 1.49
L1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth. Mol Cell Biol (2005) 1.47
Regulatory T cells. J Invest Dermatol (2006) 1.47
Expression of stem cell markers in human astrocytomas of different WHO grades. J Neurooncol (2007) 1.46
Ligand binding and calcium influx induce distinct ectodomain/gamma-secretase-processing pathways of EphB2 receptor. J Biol Chem (2007) 1.44
No evidence of transdifferentiation of human endothelial progenitor cells into cardiomyocytes after coculture with neonatal rat cardiomyocytes. Circulation (2006) 1.39
The role of ADAM-mediated shedding in vascular biology. Eur J Cell Biol (2011) 1.38
Impaired sphingomyelinase activity and epidermal differentiation in atopic dermatitis. J Invest Dermatol (2004) 1.37
Hypermetabolism in mice caused by the central action of an unliganded thyroid hormone receptor alpha1. EMBO J (2007) 1.33
Tamoxifen-inducible gene deletion in the cardiac conduction system. J Mol Cell Cardiol (2008) 1.32
Regulated shedding of transmembrane chemokines by the disintegrin and metalloproteinase 10 facilitates detachment of adherent leukocytes. J Immunol (2007) 1.32
UV-B radiation induces the expression of antimicrobial peptides in human keratinocytes in vitro and in vivo. J Allergy Clin Immunol (2009) 1.31
Enhanced expression and shedding of the transmembrane chemokine CXCL16 by reactive astrocytes and glioma cells. J Neurochem (2005) 1.28
Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation. J Exp Med (2008) 1.27
CXCR6 promotes atherosclerosis by supporting T-cell homing, interferon-gamma production, and macrophage accumulation in the aortic wall. Circulation (2007) 1.27
alpha-Melanocyte-stimulating hormone protects from ultraviolet radiation-induced apoptosis and DNA damage. J Biol Chem (2004) 1.26
RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity. Nat Neurosci (2007) 1.26
Removal of Ca2+ channel beta3 subunit enhances Ca2+ oscillation frequency and insulin exocytosis. Cell (2004) 1.22
A disintegrin and metalloproteinase 17 (ADAM17) mediates inflammation-induced shedding of syndecan-1 and -4 by lung epithelial cells. J Biol Chem (2009) 1.22
Inhibition of TNF receptor 1 internalization by adenovirus 14.7K as a novel immune escape mechanism. J Clin Invest (2006) 1.20
Dominant-negative suppression of HCN channels markedly reduces the native pacemaker current I(f) and undermines spontaneous beating of neonatal cardiomyocytes. Circulation (2003) 1.20
ADAM10-mediated E-cadherin release is regulated by proinflammatory cytokines and modulates keratinocyte cohesion in eczematous dermatitis. J Invest Dermatol (2008) 1.20
Regulated ADAM10-dependent ectodomain shedding of gamma-protocadherin C3 modulates cell-cell adhesion. J Biol Chem (2006) 1.19
Pacemaker channels and sinus node arrhythmia. Trends Cardiovasc Med (2004) 1.18
The antimicrobial protein psoriasin (S100A7) is upregulated in atopic dermatitis and after experimental skin barrier disruption. J Invest Dermatol (2008) 1.18
AtSUC8 and AtSUC9 encode functional sucrose transporters, but the closely related AtSUC6 and AtSUC7 genes encode aberrant proteins in different Arabidopsis ecotypes. Plant J (2004) 1.17
Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases. Blood (2009) 1.17
Nrf2 establishes a glutathione-mediated gradient of UVB cytoprotection in the epidermis. Genes Dev (2010) 1.17
A HCN4+ cardiomyogenic progenitor derived from the first heart field and human pluripotent stem cells. Nat Cell Biol (2013) 1.16
Bradycardic and proarrhythmic properties of sinus node inhibitors. Mol Pharmacol (2005) 1.16
Evidence for a role of ADAM17 (TACE) in the regulation of platelet glycoprotein V. J Biol Chem (2005) 1.15
Membrane resting potential of thalamocortical relay neurons is shaped by the interaction among TASK3 and HCN2 channels. J Neurophysiol (2006) 1.14
Human EML4, a novel member of the EMAP family, is essential for microtubule formation. Exp Cell Res (2006) 1.13
Pathophysiology of HCN channels. Pflugers Arch (2007) 1.13
Consequences of monocarboxylate transporter 8 deficiency for renal transport and metabolism of thyroid hormones in mice. Endocrinology (2009) 1.13
Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice. J Clin Invest (2012) 1.12
Novel insights into the distribution of cardiac HCN channels: an expression study in the mouse heart. J Mol Cell Cardiol (2011) 1.12
Cathepsin D is involved in the regulation of transglutaminase 1 and epidermal differentiation. J Cell Sci (2004) 1.10
Retracted Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serum. Mol Cell Biol (2005) 1.10
Different properties of VEGF-antagonists: Bevacizumab but not Ranibizumab accumulates in RPE cells. Graefes Arch Clin Exp Ophthalmol (2009) 1.09
Pain perception in mice lacking the beta3 subunit of voltage-activated calcium channels. J Biol Chem (2002) 1.07
A systems model for immune cell interactions unravels the mechanism of inflammation in human skin. PLoS Comput Biol (2010) 1.07
Breaking up the tie: disintegrin-like metalloproteinases as regulators of cell migration in inflammation and invasion. Pharmacol Ther (2006) 1.07
Functional dissection of the epidermal growth factor receptor epitopes targeted by panitumumab and cetuximab. Neoplasia (2012) 1.07
Mouse beta-defensin-14, an antimicrobial ortholog of human beta-defensin-3. Antimicrob Agents Chemother (2008) 1.07
Tumoural CXCL16 expression is a novel prognostic marker of longer survival times in renal cell cancer patients. Eur J Cancer (2008) 1.06
Generation of thyrotropin-releasing hormone receptor 1-deficient mice as an animal model of central hypothyroidism. Mol Endocrinol (2004) 1.05
Tumor necrosis factor alpha activates release of B lymphocyte stimulator by neutrophils infiltrating the rheumatoid joint. Arthritis Rheum (2007) 1.04
One century of hydrological monitoring in two small catchments with different forest coverage. Environ Monit Assess (2010) 1.03
Cooperative binding of Sox10 to DNA: requirements and consequences. Nucleic Acids Res (2002) 1.03
IEX-1 directly interferes with RelA/p65 dependent transactivation and regulation of apoptosis. Biochim Biophys Acta (2007) 1.03
Tetraspanins regulate ADAM10-mediated cleavage of TNF-alpha and epidermal growth factor. J Immunol (2008) 1.03
Inappropriate heat dissipation ignites brown fat thermogenesis in mice with a mutant thyroid hormone receptor α1. Proc Natl Acad Sci U S A (2013) 1.02
ADAM10 is the constitutive functional sheddase of CD44 in human melanoma cells. J Invest Dermatol (2008) 1.02
The interleukin-6 cytokine system regulates epidermal permeability barrier homeostasis. J Invest Dermatol (2004) 1.01
Molecular mechanisms of ultraviolet radiation-induced immunosuppression. Eur J Cell Biol (2010) 1.01
The angiotensin-calcineurin-NFAT pathway mediates stretch-induced up-regulation of matrix metalloproteinases-2/-9 in atrial myocytes. Basic Res Cardiol (2009) 1.01
Lymphatic spread of ductal pancreatic adenocarcinoma is independent of lymphangiogenesis. J Pathol (2005) 1.01
Retracted Natural soluble interleukin-15Ralpha is generated by cleavage that involves the tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17). J Biol Chem (2004) 1.01
Severe psychomotor and metabolic damages caused by a mutant thyroid hormone receptor alpha 1 in mice: can patients with a similar mutation be found and treated? Acta Paediatr (2008) 1.00
Mechanical and metabolic injury to the skin barrier leads to increased expression of murine β-defensin-1, -3, and -14. J Invest Dermatol (2010) 0.99
Phenotypic and functional characterization of ultraviolet radiation-induced regulatory T cells. J Immunol (2008) 0.99
Foxp3-mediated suppression of CD95L expression confers resistance to activation-induced cell death in regulatory T cells. J Immunol (2011) 0.98
Involvement of dectin-2 in ultraviolet radiation-induced tolerance. J Immunol (2003) 0.98
Dendritic HCN2 channels constrain glutamate-driven excitability in reticular thalamic neurons. J Neurosci (2007) 0.98
The thyroid hormone receptor alpha1 protein is expressed in embryonic postmitotic neurons and persists in most adult neurons. Mol Endocrinol (2010) 0.97
Characterization of CXCL16 and ADAM10 in the normal and transplanted kidney. Kidney Int (2008) 0.97
Hypoxia and oxygenation induce a metabolic switch between pentose phosphate pathway and glycolysis in glioma stem-like cells. Acta Neuropathol (2013) 0.96