David Fushman

Author PubWeight™ 86.84‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Polyubiquitin chains: polymeric protein signals. Curr Opin Chem Biol 2004 7.10
2 Atom-by-atom analysis of global downhill protein folding. Nature 2006 4.50
3 Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling. J Biol Chem 2003 3.30
4 Diverse polyubiquitin interaction properties of ubiquitin-associated domains. Nat Struct Mol Biol 2005 3.27
5 Structural determinants for selective recognition of a Lys48-linked polyubiquitin chain by a UBA domain. Mol Cell 2005 2.92
6 Structural properties of polyubiquitin chains in solution. J Mol Biol 2002 2.72
7 Ubistatins inhibit proteasome-dependent degradation by binding the ubiquitin chain. Science 2004 2.50
8 Crystal structure and solution NMR studies of Lys48-linked tetraubiquitin at neutral pH. J Mol Biol 2006 2.22
9 Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1. J Mol Biol 2009 1.82
10 Characterization of the overall and local dynamics of a protein with intermediate rotational anisotropy: Differentiating between conformational exchange and anisotropic diffusion in the B3 domain of protein G. J Biomol NMR 2003 1.72
11 Affinity makes the difference: nonselective interaction of the UBA domain of Ubiquilin-1 with monomeric ubiquitin and polyubiquitin chains. J Mol Biol 2007 1.71
12 A model of interdomain mobility in a multidomain protein. J Am Chem Soc 2007 1.66
13 Unique structural, dynamical, and functional properties of k11-linked polyubiquitin chains. Structure 2013 1.61
14 Analyses of the effects of all ubiquitin point mutants on yeast growth rate. J Mol Biol 2013 1.59
15 Structure of the s5a:k48-linked diubiquitin complex and its interactions with rpn13. Mol Cell 2009 1.57
16 Interdomain mobility in di-ubiquitin revealed by NMR. Proteins 2006 1.55
17 Together, Rpn10 and Dsk2 can serve as a polyubiquitin chain-length sensor. Mol Cell 2009 1.47
18 Avid interactions underlie the Lys63-linked polyubiquitin binding specificities observed for UBA domains. Nat Struct Mol Biol 2009 1.35
19 Efficient and accurate determination of the overall rotational diffusion tensor of a molecule from (15)N relaxation data using computer program ROTDIF. J Magn Reson 2004 1.32
20 Variability of the 15N chemical shielding tensors in the B3 domain of protein G from 15N relaxation measurements at several fields. Implications for backbone order parameters. J Am Chem Soc 2006 1.30
21 Various strategies of using residual dipolar couplings in NMR-driven protein docking: application to Lys48-linked di-ubiquitin and validation against 15N-relaxation data. Proteins 2005 1.26
22 An efficient computational method for predicting rotational diffusion tensors of globular proteins using an ellipsoid representation. J Am Chem Soc 2006 1.22
23 Nonenzymatic assembly of natural polyubiquitin chains of any linkage composition and isotopic labeling scheme. J Am Chem Soc 2011 1.17
24 Rpn1 and Rpn2 coordinate ubiquitin processing factors at proteasome. J Biol Chem 2012 1.15
25 Mapping the interactions between Lys48 and Lys63-linked di-ubiquitins and a ubiquitin-interacting motif of S5a. J Mol Biol 2007 1.09
26 Mixed-linkage ubiquitin chains send mixed messages. Structure 2013 1.09
27 Structure and recognition of polyubiquitin chains of different lengths and linkage. F1000 Biol Rep 2011 1.08
28 Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins. J Mol Biol 2007 1.07
29 Structural assembly of multidomain proteins and protein complexes guided by the overall rotational diffusion tensor. J Am Chem Soc 2007 1.03
30 Recovering a representative conformational ensemble from underdetermined macromolecular structural data. J Am Chem Soc 2013 1.00
31 Controlled enzymatic synthesis of natural-linkage, defined-length polyubiquitin chains using lysines with removable protecting groups. Chem Commun (Camb) 2011 0.98
32 Structural and biochemical studies of the open state of Lys48-linked diubiquitin. Biochim Biophys Acta 2012 0.97
33 A hierarchical algorithm for fast Debye summation with applications to small angle scattering. J Comput Chem 2012 0.96
34 Improvement and analysis of computational methods for prediction of residual dipolar couplings. J Magn Reson 2009 0.95
35 Structural assembly of molecular complexes based on residual dipolar couplings. J Am Chem Soc 2010 0.94
36 Analysis of interdomain dynamics in a two-domain protein using residual dipolar couplings together with 15N relaxation data. Magn Reson Chem 2006 0.93
37 Recognition and cleavage of related to ubiquitin 1 (Rub1) and Rub1-ubiquitin chains by components of the ubiquitin-proteasome system. Mol Cell Proteomics 2012 0.93
38 Proteomic identification and analysis of K63-linked ubiquitin conjugates. Anal Chem 2012 0.93
39 Perturbing the ubiquitin pathway reveals how mitosis is hijacked to denucleate and regulate cell proliferation and differentiation in vivo. PLoS One 2010 0.92
40 Direct measurement of the 15N CSA/dipolar relaxation interference from coupled HSQC spectra. J Biomol NMR 2003 0.92
41 Measurement of 15N relaxation in deuterated amide groups in proteins using direct nitrogen detection. J Biomol NMR 2006 0.92
42 Condensed E. coli cultures for highly efficient production of proteins containing unnatural amino acids. Bioorg Med Chem Lett 2010 0.91
43 Density functional calculations of 15N chemical shifts in solvated dipeptides. J Biomol NMR 2008 0.90
44 Effects of cyclization on conformational dynamics and binding properties of Lys48-linked di-ubiquitin. Protein Sci 2007 0.90
45 Deriving quantitative dynamics information for proteins and RNAs using ROTDIF with a graphical user interface. J Biomol NMR 2013 0.88
46 Using NMR spectroscopy to monitor ubiquitin chain conformation and interactions with ubiquitin-binding domains. Methods Enzymol 2005 0.87
47 Density functional calculations of chemical shielding of backbone 15N in helical residues of protein G. J Biomol NMR 2009 0.86
48 Density functional calculations of backbone 15N shielding tensors in beta-sheet and turn residues of protein G. J Biomol NMR 2011 0.86
49 Segmental isotopic labeling of ubiquitin chains to unravel monomer-specific molecular behavior. Angew Chem Int Ed Engl 2011 0.85
50 Spin-state selection for increased confidence in cross-correlation rates measurements. J Biomol NMR 2005 0.85
51 Nonenzymatic assembly of branched polyubiquitin chains for structural and biochemical studies. Bioorg Med Chem 2013 0.84
52 Characterization of the overall rotational diffusion of a protein from 15N relaxation measurements and hydrodynamic calculations. Methods Mol Biol 2004 0.84
53 Reversible post-translational carboxylation modulates the enzymatic activity of N-acetyl-L-ornithine transcarbamylase. Biochemistry 2010 0.81
54 Preparing to read the ubiquitin code: a middle-out strategy for characterization of all lysine-linked diubiquitins. J Mass Spectrom 2014 0.81
55 Unexpected trypsin cleavage at ubiquitinated lysines. Anal Chem 2015 0.81
56 High relaxivity supramolecular adducts between human-liver fatty-acid-binding protein and amphiphilic Gd(III) complexes: structural basis for the design of intracellular targeting MRI probes. Chemistry 2012 0.81
57 Evidence for cooperative and domain-specific binding of the signal transducing adaptor molecule 2 (STAM2) to Lys63-linked diubiquitin. J Biol Chem 2012 0.80
58 Fast approximations of the rotational diffusion tensor and their application to structural assembly of molecular complexes. Proteins 2011 0.80
59 Polyhydroxylated [60]fullerene binds specifically to functional recognition sites on a monomeric and a dimeric ubiquitin. Nanoscale 2015 0.79
60 Information content of long-range NMR data for the characterization of conformational heterogeneity. J Biomol NMR 2015 0.78
61 Nonenzymatic rubylation and ubiquitination of proteins for structural and functional studies. Angew Chem Int Ed Engl 2014 0.78
62 Modifying the vicinity of the isopeptide bond to reveal differential behavior of ubiquitin chains with interacting proteins: organic chemistry applied to synthetic proteins. Angew Chem Int Ed Engl 2013 0.77
63 1H, 13C, and 15N resonance assignment of the ubiquitin-like domain from Dsk2p. Biomol NMR Assign 2008 0.76
64 Long-lived states to monitor protein unfolding by proton NMR. Chemphyschem 2011 0.75
65 Probing the Binding Modes of a Multi-Domain Protein to Lipid-Based Nanoparticles by Relaxation-Based NMR. J Phys Chem Lett 2017 0.75