Published in Neurosci Lett on March 12, 2007
STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels. Cell (2007) 3.75
Regulation of NMDA receptor subunit expression and its implications for LTD, LTP, and metaplasticity. Neuropharmacology (2008) 3.30
Effect of aging on cellular mechanotransduction. Ageing Res Rev (2009) 1.04
Alterations in neuronal calcium levels are associated with cognitive deficits after traumatic brain injury. Neurosci Lett (2008) 1.02
Development of status epilepticus, sustained calcium elevations and neuronal injury in a rat survival model of lethal paraoxon intoxication. Neurotoxicology (2014) 0.90
The fragile X mental retardation protein developmentally regulates the strength and fidelity of calcium signaling in Drosophila mushroom body neurons. Neurobiol Dis (2010) 0.89
Neuroprotection by glutamate receptor antagonists against seizure-induced excitotoxic cell death in the aging brain. Exp Neurol (2010) 0.84
Hippocampal gene expression dysregulation of Klotho, nuclear factor kappa B and tumor necrosis factor in temporal lobe epilepsy patients. J Neuroinflammation (2013) 0.83
Estradiol reverses a calcium-related biomarker of brain aging in female rats. J Neurosci (2009) 0.83
Native store-operated calcium channels are functionally expressed in mouse spinal cord dorsal horn neurons and regulate resting calcium homeostasis. J Physiol (2014) 0.82
Role of creatine supplementation on exercise-induced cardiovascular function and oxidative stress. Oxid Med Cell Longev (2010) 0.81
Chronic behavioral and cognitive deficits in a rat survival model of paraoxon toxicity. Neurotoxicology (2014) 0.77
Preparation of primary neurons for visualizing neurites in a frozen-hydrated state using cryo-electron tomography. J Vis Exp (2014) 0.77
Neurobiology of vascular dementia. J Aging Res (2011) 0.77
Are there roles for brain cell senescence in aging and neurodegenerative disorders? Biogerontology (2014) 0.76
Mitochondrial protein Fus1/Tusc2 in premature aging and age-related pathologies: critical roles of calcium and energy homeostasis. Aging (Albany NY) (2017) 0.75
Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity. Cell Calcium (2003) 2.21
Increase in single L-type calcium channels in hippocampal neurons during aging. Science (1996) 2.03
Cellular mechanisms underlying acquired epilepsy: the calcium hypothesis of the induction and maintainance of epilepsy. Pharmacol Ther (2004) 1.94
Calcium and neuronal ageing. Trends Neurosci (1998) 1.73
Elevated postsynaptic [Ca2+]i and L-type calcium channel activity in aged hippocampal neurons: relationship to impaired synaptic plasticity. J Neurosci (2001) 1.67
Early and simultaneous emergence of multiple hippocampal biomarkers of aging is mediated by Ca2+-induced Ca2+ release. J Neurosci (2006) 1.48
Aging changes in voltage-gated calcium currents in hippocampal CA1 neurons. J Neurosci (1996) 1.32
Calcium channel density and hippocampal cell death with age in long-term culture. J Neurosci (1997) 1.29
Loss of calbindin-D28k from aging human cholinergic basal forebrain: relation to neuronal loss. J Comp Neurol (2003) 1.25
Evidence that injury-induced changes in hippocampal neuronal calcium dynamics during epileptogenesis cause acquired epilepsy. Proc Natl Acad Sci U S A (2004) 1.24
Long-term alteration of calcium homeostatic mechanisms in the pilocarpine model of temporal lobe epilepsy. Brain Res (2001) 1.05
Effects of aging on sarcoplasmic reticulum Ca2+-cycling proteins and their phosphorylation in rat myocardium. Am J Physiol (1998) 1.01
Inability to restore resting intracellular calcium levels as an early indicator of delayed neuronal cell death. Brain Res (1995) 1.00
Cytosolic Ca2+ binding proteins during rat brain ageing: loss of calbindin and calretinin in the hippocampus, with no change in the cerebellum. Eur J Neurosci (1994) 0.99
Calcium chelation improves spatial learning and synaptic plasticity in aged rats. Exp Neurol (2005) 0.97
Up-regulation of alpha1D Ca2+ channel subunit mRNA expression in the hippocampus of aged F344 rats. Neurobiol Aging (1999) 0.96
Changes in mitochondrial status associated with altered Ca2+ homeostasis in aged cerebellar granule neurons in brain slices. J Neurosci (2002) 0.96
Long-lasting alterations in neuronal calcium homeostasis in an in vitro model of stroke-induced epilepsy. Cell Calcium (2004) 0.95
Mitochondrial polarisation status and [Ca2+]i signalling in rat cerebellar granule neurones aged in vitro. Neurobiol Aging (2004) 0.94
Regionally selective alterations in expression of the alpha(1D) subunit (Ca(v)1.3) of L-type calcium channels in the hippocampus of aged rats. Brain Res Mol Brain Res (2002) 0.94
Expression of alpha 1D subunit mRNA is correlated with L-type Ca2+ channel activity in single neurons of hippocampal "zipper" slices. Proc Natl Acad Sci U S A (2000) 0.93
Adrenergic nerve smooth endoplasmic reticulum calcium buffering declines with age. Neurobiol Aging (1998) 0.93
Dysregulation of calcium in Alzheimer's disease. Acta Neurobiol Exp (Wars) (2003) 0.88
Hippocampal neurons exhibit both persistent Ca2+ influx and impairment of Ca2+ sequestration/extrusion mechanisms following excitotoxic glutamate exposure. Brain Res (2001) 0.84
Autoradiography of L-type and N-type calcium channels in aged rat hippocampus, entorhinal cortex, and neocortex. Neurobiol Aging (2001) 0.81
Age-related changes in parvalbumin- and GABA-immunoreactive cells in the rat septum. Neurobiol Aging (1995) 0.81
Age-related reduced affinity in [3H]nitrendipine labeling of brain voltage-dependent calcium channels. Brain Res (1985) 0.81
Cellular mechanisms underlying acquired epilepsy: the calcium hypothesis of the induction and maintainance of epilepsy. Pharmacol Ther (2004) 1.94
The endogenous cannabinoid system regulates seizure frequency and duration in a model of temporal lobe epilepsy. J Pharmacol Exp Ther (2003) 1.93
Evidence for a physiological role of endocannabinoids in the modulation of seizure threshold and severity. Eur J Pharmacol (2002) 1.26
Evidence that injury-induced changes in hippocampal neuronal calcium dynamics during epileptogenesis cause acquired epilepsy. Proc Natl Acad Sci U S A (2004) 1.24
Traumatic brain injury causes a long-lasting calcium (Ca2+)-plateau of elevated intracellular Ca levels and altered Ca2+ homeostatic mechanisms in hippocampal neurons surviving brain injury. Eur J Neurosci (2008) 1.22
Activation of the cannabinoid type-1 receptor mediates the anticonvulsant properties of cannabinoids in the hippocampal neuronal culture models of acquired epilepsy and status epilepticus. J Pharmacol Exp Ther (2006) 1.15
Development of a prolonged calcium plateau in hippocampal neurons in rats surviving status epilepticus induced by the organophosphate diisopropylfluorophosphate. Toxicol Sci (2010) 1.14
Time course and mechanism of hippocampal neuronal death in an in vitro model of status epilepticus: role of NMDA receptor activation and NMDA dependent calcium entry. Eur J Pharmacol (2008) 1.04
Cannabinoid CB1 receptor antagonists cause status epilepticus-like activity in the hippocampal neuronal culture model of acquired epilepsy. Neurosci Lett (2006) 1.03
Alterations in neuronal calcium levels are associated with cognitive deficits after traumatic brain injury. Neurosci Lett (2008) 1.02
Development of the calcium plateau following status epilepticus: role of calcium in epileptogenesis. Expert Rev Neurother (2009) 0.97
Epileptogenesis causes acute and chronic increases in GABAA receptor endocytosis that contributes to the induction and maintenance of seizures in the hippocampal culture model of acquired epilepsy. J Pharmacol Exp Ther (2004) 0.96
Prolonged exposure to WIN55,212-2 causes downregulation of the CB1 receptor and the development of tolerance to its anticonvulsant effects in the hippocampal neuronal culture model of acquired epilepsy. Neuropharmacology (2009) 0.95
Long-term decrease in calbindin-D28K expression in the hippocampus of epileptic rats following pilocarpine-induced status epilepticus. Epilepsy Res (2008) 0.95
Long-lasting alterations in neuronal calcium homeostasis in an in vitro model of stroke-induced epilepsy. Cell Calcium (2004) 0.95
Preservation of splenic immunocompetence after splenic artery angioembolization for blunt splenic injury. J Trauma (2010) 0.94
Calcium-dependent epileptogenesis in an in vitro model of stroke-induced "epilepsy". Epilepsia (2002) 0.94
Endocannabinoids block status epilepticus in cultured hippocampal neurons. Eur J Pharmacol (2006) 0.91
Levetiracetam inhibits both ryanodine and IP3 receptor activated calcium induced calcium release in hippocampal neurons in culture. Neurosci Lett (2008) 0.89
In vitro status epilepticus but not spontaneous recurrent seizures cause cell death in cultured hippocampal neurons. Epilepsy Res (2007) 0.89
Development of pharmacoresistance to benzodiazepines but not cannabinoids in the hippocampal neuronal culture model of status epilepticus. Exp Neurol (2007) 0.88
Carisbamate prevents the development and expression of spontaneous recurrent epileptiform discharges and is neuroprotective in cultured hippocampal neurons. Epilepsia (2008) 0.88
Epileptogenesis causes an N-methyl-d-aspartate receptor/Ca2+-dependent decrease in Ca2+/calmodulin-dependent protein kinase II activity in a hippocampal neuronal culture model of spontaneous recurrent epileptiform discharges. Eur J Pharmacol (2008) 0.87
Altered calcium/calmodulin kinase II activity changes calcium homeostasis that underlies epileptiform activity in hippocampal neurons in culture. J Pharmacol Exp Ther (2006) 0.87
Temporal characterization of changes in hippocampal cannabinoid CB(1) receptor expression following pilocarpine-induced status epilepticus. Brain Res (2009) 0.86
Basic research in epilepsy and aging. Epilepsy Res (2005) 0.85
Activation of a novel injury-induced calcium-permeable channel that plays a key role in causing extended neuronal depolarization and initiating neuronal death in excitotoxic neuronal injury. J Pharmacol Exp Ther (2007) 0.85
Comparisons of the mortality and clinical presentations of status epilepticus in private practice community and university hospital settings in Richmond, Virginia. Seizure (2009) 0.84
Anticonvulsant effect of FS-1 subfraction isolated from roots of Delphinim denudatum on hippocampal pyramidal neurons. Phytother Res (2003) 0.84
An in vitro model of stroke-induced epilepsy: elucidation of the roles of glutamate and calcium in the induction and maintenance of stroke-induced epileptogenesis. Int Rev Neurobiol (2007) 0.83
An organotypic hippocampal slice culture model of excitotoxic injury induced spontaneous recurrent epileptiform discharges. Brain Res (2010) 0.83
Dantrolene inhibits the calcium plateau and prevents the development of spontaneous recurrent epileptiform discharges following in vitro status epilepticus. Eur J Neurosci (2010) 0.82
The novel antiepileptic drug carisbamate (RWJ 333369) is effective in inhibiting spontaneous recurrent seizure discharges and blocking sustained repetitive firing in cultured hippocampal neurons. Epilepsy Res (2008) 0.82
Erratum to "Cellular mechanisms underlying acquired epilepsy: the calcium hypothesis of the induction and maintenance of epilepsy." [Pharmacol. Ther. 105(3) (2005) 229-266]. Pharmacol Ther (2006) 0.81
Prolonged cannabinoid exposure alters GABA(A) receptor mediated synaptic function in cultured hippocampal neurons. Exp Neurol (2011) 0.80
Neuronal-specific endoplasmic reticulum Mg(2+)/Ca(2+) ATPase Ca(2+) sequestration in mixed primary hippocampal culture homogenates. Anal Biochem (2004) 0.78
Acetaminophen inhibits status epilepticus in cultured hippocampal neurons. Neuroreport (2011) 0.78
Status epilepticus in a population-based Virginia twin sample. Epilepsia (2004) 0.77
NMDA channel antagonist MK-801 does not protect against bilirubin neurotoxicity. Neonatology (2007) 0.77
The neurosteroid 3 alpha-hydroxy-5 alpha-pregnan-20-one affects dopamine-mediated behavior in rodents. Psychopharmacology (Berl) (2002) 0.77
Statistical parametric mapping reveals regional alterations in cannabinoid CB1 receptor distribution and G-protein activation in the 3D reconstructed epileptic rat brain. Epilepsia (2012) 0.76
Age-dependent mortality in the pilocarpine model of status epilepticus. Neurosci Lett (2009) 0.76
Hypothermia reduces calcium entry via the N-methyl-D-aspartate and ryanodine receptors in cultured hippocampal neurons. Eur J Pharmacol (2012) 0.75
Induction of prolonged electrographic seizures in vitro has a defined threshold and is all or none: implications for diagnosis of status epilepticus. Epilepsia (2003) 0.75
Cannabinoids: is there a potential treatment role in epilepsy? Expert Opin Pharmacother (2015) 0.75
Characterization of spontaneous recurrent epileptiform discharges in hippocampal-entorhinal cortical slices prepared from chronic epileptic animals. Seizure (2010) 0.75
In vitro inhibition of pentylenetetrazole and bicuculline-induced epileptiform activity in rat hippocampal pyramidal neurons by aqueous fraction isolated from Delphinium denudatum. Neurosci Lett (2002) 0.75
Inhibition of sustained repetitive firing in cultured hippocampal neurons by an aqueous fraction isolated from Delphinium denudatum. J Ethnopharmacol (2004) 0.75