Published in Oncology on March 21, 2007
UPLC-ESI-TOFMS-based metabolomics and gene expression dynamics inspector self-organizing metabolomic maps as tools for understanding the cellular response to ionizing radiation. Anal Chem (2008) 1.61
Possible renoprotection by vitamin D in chronic renal disease: beyond mineral metabolism. Nat Rev Nephrol (2009) 1.51
HDAC3 impacts multiple oncogenic pathways in colon cancer cells with effects on Wnt and vitamin D signaling. Cancer Biol Ther (2008) 1.13
Vitamin D Receptor Genetic Polymorphisms and Prostate Cancer Risk: A Meta-analysis of 36 Published Studies. Int J Clin Exp Med (2009) 0.98
Elevated NCOR1 disrupts PPARalpha/gamma signaling in prostate cancer and forms a targetable epigenetic lesion. Carcinogenesis (2010) 0.95
Recruitment of NCOR1 to VDR target genes is enhanced in prostate cancer cells and associates with altered DNA methylation patterns. Carcinogenesis (2012) 0.91
Vitamin D and the RNA transcriptome: more than mRNA regulation. Front Physiol (2014) 0.88
Anti-proliferative action of vitamin D in MCF7 is still active after siRNA-VDR knock-down. BMC Genomics (2009) 0.87
Nutrigenomics, vitamin D and cancer prevention. J Nutrigenet Nutrigenomics (2011) 0.86
Global maternal early pregnancy peripheral blood mRNA and miRNA expression profiles according to plasma 25-hydroxyvitamin D concentrations. J Matern Fetal Neonatal Med (2011) 0.85
Transcriptional effects of 1,25 dihydroxyvitamin D(3) physiological and supra-physiological concentrations in breast cancer organotypic culture. BMC Cancer (2013) 0.84
Mechanistic Effects of Calcitriol in Cancer Biology. Nutrients (2015) 0.82
The coregulator Alien. Nucl Recept Signal (2007) 0.77
Knockdown of AKR1C3 exposes a potential epigenetic susceptibility in prostate cancer cells. J Steroid Biochem Mol Biol (2015) 0.76
Vitamin D receptor and RXR in the post-genomic era. J Cell Physiol (2015) 0.76
Vitamin D Deficiency Promotes Liver Tumor Growth in Transforming Growth Factor-β/Smad3-Deficient Mice Through Wnt and Toll-like Receptor 7 Pathway Modulation. Sci Rep (2016) 0.75
Association between vitamin D receptor gene polymorphisms and breast cancer in a Chinese population. Int J Clin Exp Med (2015) 0.75
Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science (2006) 18.74
Academic medicine: a faltering engine. BMJ (2002) 8.12
Corticosteroid insufficiency in acutely ill patients. N Engl J Med (2003) 6.00
Improving clinical research. BMJ (2003) 5.23
The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab (2008) 4.90
Bayesian variable selection in multinomial probit models to identify molecular signatures of disease stage. Biometrics (2004) 4.71
Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity. Nat Clin Pract Endocrinol Metab (2008) 4.61
Update in vitamin D. J Clin Endocrinol Metab (2010) 4.48
Distribution of the vitamin D receptor and 1 alpha-hydroxylase in human brain. J Chem Neuroanat (2005) 4.14
11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response. Endocr Rev (2004) 3.56
GALGO: an R package for multivariate variable selection using genetic algorithms. Bioinformatics (2006) 3.54
Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages. Sci Transl Med (2011) 3.27
Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin. Arthritis Res Ther (2005) 3.17
How should we rate research? BMJ (2006) 2.65
Congenital adrenal hyperplasia caused by mutant P450 oxidoreductase and human androgen synthesis: analytical study. Lancet (2004) 2.49
Vitamin d-directed rheostatic regulation of monocyte antibacterial responses. J Immunol (2009) 2.45
A Bayesian approach to reconstructing genetic regulatory networks with hidden factors. Bioinformatics (2004) 2.38
Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science (2013) 2.34
Effect of spironolactone on left ventricular mass and aortic stiffness in early-stage chronic kidney disease: a randomized controlled trial. J Am Coll Cardiol (2009) 2.30
1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3. J Immunol (2009) 2.22
Dosage compensation in the mouse balances up-regulation and silencing of X-linked genes. PLoS Biol (2007) 2.06
Modeling T-cell activation using gene expression profiling and state-space models. Bioinformatics (2004) 2.02
Synthesis of 1,25-dihydroxyvitamin D(3) by human endothelial cells is regulated by inflammatory cytokines: a novel autocrine determinant of vascular cell adhesion. J Am Soc Nephrol (2002) 2.02
Osteoblastic 11beta-hydroxysteroid dehydrogenase type 1 activity increases with age and glucocorticoid exposure. J Bone Miner Res (2002) 1.94
Low energy diet and intracranial pressure in women with idiopathic intracranial hypertension: prospective cohort study. BMJ (2010) 1.90
Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in pancreatic islets. J Steroid Biochem Mol Biol (2004) 1.89
Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor. Nucleic Acids Res (2006) 1.89
Urine steroid metabolomics as a biomarker tool for detecting malignancy in adrenal tumors. J Clin Endocrinol Metab (2011) 1.86
Vitamin D and placental-decidual function. J Soc Gynecol Investig (2004) 1.79
IL-15 links TLR2/1-induced macrophage differentiation to the vitamin D-dependent antimicrobial pathway. J Immunol (2008) 1.79
Vitamin D-binding protein directs monocyte responses to 25-hydroxy- and 1,25-dihydroxyvitamin D. J Clin Endocrinol Metab (2010) 1.72
11beta-hydroxysteroid dehydrogenase and the pre-receptor regulation of corticosteroid hormone action. J Endocrinol (2005) 1.70
Different proliferative potential and migratory characteristics of human CD4+ regulatory T cells that express either CD45RA or CD45RO. J Immunol (2010) 1.66
Gas chromatography/mass spectrometry (GC/MS) remains a pre-eminent discovery tool in clinical steroid investigations even in the era of fast liquid chromatography tandem mass spectrometry (LC/MS/MS). J Steroid Biochem Mol Biol (2010) 1.63
Vitamin D in defense of the human immune response. Ann N Y Acad Sci (2007) 1.63
Multiplex bead immunoassay analysis of aqueous humor reveals distinct cytokine profiles in uveitis. Invest Ophthalmol Vis Sci (2005) 1.61
Outcome of Cushing's disease following transsphenoidal surgery in a single center over 20 years. J Clin Endocrinol Metab (2012) 1.61
Hyperandrogenemia predicts metabolic phenotype in polycystic ovary syndrome: the utility of serum androstenedione. J Clin Endocrinol Metab (2014) 1.61
No evidence for hepatic conversion of dehydroepiandrosterone (DHEA) sulfate to DHEA: in vivo and in vitro studies. J Clin Endocrinol Metab (2005) 1.59
Biomarker discovery in microarray gene expression data with Gaussian processes. Bioinformatics (2005) 1.59
Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency. Nat Genet (2003) 1.58
Autocrine metabolism of vitamin D in normal and malignant breast tissue. Clin Cancer Res (2005) 1.58
Effects of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on cytokine production by human decidual cells. Biol Reprod (2006) 1.57
Hexose-6-phosphate dehydrogenase knock-out mice lack 11 beta-hydroxysteroid dehydrogenase type 1-mediated glucocorticoid generation. J Biol Chem (2005) 1.57
Divergence of macrophage phagocytic and antimicrobial programs in leprosy. Cell Host Microbe (2009) 1.55
Global gene expression profiles in fibroblasts from synovial, skin and lymphoid tissue reveals distinct cytokine and chemokine expression patterns. Thromb Haemost (2003) 1.55
Discovery of metabolic signatures for predicting whole organism toxicology. Toxicol Sci (2010) 1.52
Vitamin D deficiency in mice impairs colonic antibacterial activity and predisposes to colitis. Endocrinology (2010) 1.51
1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients. J Alzheimers Dis (2009) 1.51
Regulators encoded in the Escherichia coli type III secretion system 2 gene cluster influence expression of genes within the locus for enterocyte effacement in enterohemorrhagic E. coli O157:H7. Infect Immun (2004) 1.49
Mortality in patients with pituitary disease. Endocr Rev (2010) 1.48
Rare causes of calcitriol-mediated hypercalcemia: a case report and literature review. J Clin Endocrinol Metab (2010) 1.48
Global transcriptional response to vancomycin in Mycobacterium tuberculosis. Microbiology (2009) 1.46
Biological actions of extra-renal 25-hydroxyvitamin D-1alpha-hydroxylase and implications for chemoprevention and treatment. J Steroid Biochem Mol Biol (2005) 1.45
Vitamin D deficiency modulates Graves' hyperthyroidism induced in BALB/c mice by thyrotropin receptor immunization. Endocrinology (2008) 1.45
Altered endocrine and autocrine metabolism of vitamin D in a mouse model of gastrointestinal inflammation. Endocrinology (2008) 1.44
T-cell cytokines differentially control human monocyte antimicrobial responses by regulating vitamin D metabolism. Proc Natl Acad Sci U S A (2010) 1.42
A comparative quality assessment of evidence-based clinical guidelines in endocrinology. Clin Endocrinol (Oxf) (2013) 1.42
Saving lives of patients with adrenal insufficiency: a pan-European initiative? Clin Endocrinol (Oxf) (2014) 1.41
The ontogeny of 25-hydroxyvitamin D(3) 1alpha-hydroxylase expression in human placenta and decidua. Am J Pathol (2002) 1.41
Investigating hypertension in a young person. BMJ (2009) 1.39
Vitamin D: beyond bone. Ann N Y Acad Sci (2013) 1.39
DNA microarrays: a powerful genomic tool for biomedical and clinical research. Mol Med (2007) 1.38
Germinal center B cells govern their own fate via antibody feedback. J Exp Med (2013) 1.36
Reduction of the vitamin D hormonal system in kidney disease is associated with increased renal inflammation. Kidney Int (2008) 1.36
Minireview: hexose-6-phosphate dehydrogenase and redox control of 11{beta}-hydroxysteroid dehydrogenase type 1 activity. Endocrinology (2005) 1.35
11beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle. Diabetes (2009) 1.29
Localization, age- and site-dependent expression, and regulation of 11β-hydroxysteroid dehydrogenase type 1 in skin. J Invest Dermatol (2010) 1.27
Alternative splicing of vitamin D-24-hydroxylase: a novel mechanism for the regulation of extrarenal 1,25-dihydroxyvitamin D synthesis. J Biol Chem (2005) 1.26
Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1. J Mol Endocrinol (2005) 1.26
Pomegranate extracts potently suppress proliferation, xenograft growth, and invasion of human prostate cancer cells. J Med Food (2004) 1.26
25-hydroxyvitamin D(3)-1alpha-hydroxylase expression in normal and pathological parathyroid glands. J Clin Endocrinol Metab (2002) 1.24
Relative overexpression of X-linked genes in mouse embryonic stem cells is consistent with Ohno's hypothesis. Nat Genet (2011) 1.22
The vitamin D receptor in cancer. Proc Nutr Soc (2008) 1.22
Altered nuclear receptor corepressor expression attenuates vitamin D receptor signaling in breast cancer cells. Clin Cancer Res (2006) 1.22
Back to the future: a new look at 'old' vitamin D. J Endocrinol (2008) 1.20
Altered SMRT levels disrupt vitamin D3 receptor signalling in prostate cancer cells. Oncogene (2004) 1.20
Diagnosis of primary aldosteronism: from screening to subtype differentiation. Trends Endocrinol Metab (2005) 1.19
Expression profiles for steroidogenic enzymes in adrenocortical disease. J Clin Endocrinol Metab (2005) 1.19
Deletion of hexose-6-phosphate dehydrogenase activates the unfolded protein response pathway and induces skeletal myopathy. J Biol Chem (2008) 1.18
Vitamin D receptor signaling mechanisms: integrated actions of a well-defined transcription factor. Steroids (2012) 1.18
Fibroblast growth factor 23 inhibits extrarenal synthesis of 1,25-dihydroxyvitamin D in human monocytes. J Bone Miner Res (2013) 1.17
Differential expression, function and response to inflammatory stimuli of 11beta-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation. Arthritis Res Ther (2006) 1.17
Increased expression of 25-hydroxyvitamin D-1alpha-hydroxylase in dysgerminomas: a novel form of humoral hypercalcemia of malignancy. Am J Pathol (2004) 1.17
Synovial fluid leukocyte apoptosis is inhibited in patients with very early rheumatoid arthritis. Arthritis Res Ther (2006) 1.16