PubRank

Martin Hewison

Author PubWeight™ 129.77‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 2006 18.74
2 Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity. Nat Clin Pract Endocrinol Metab 2008 4.61
3 Update in vitamin D. J Clin Endocrinol Metab 2010 4.48
4 Distribution of the vitamin D receptor and 1 alpha-hydroxylase in human brain. J Chem Neuroanat 2005 4.14
5 11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response. Endocr Rev 2004 3.56
6 Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages. Sci Transl Med 2011 3.27
7 Vitamin d-directed rheostatic regulation of monocyte antibacterial responses. J Immunol 2009 2.45
8 Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science 2013 2.34
9 1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3. J Immunol 2009 2.22
10 Synthesis of 1,25-dihydroxyvitamin D(3) by human endothelial cells is regulated by inflammatory cytokines: a novel autocrine determinant of vascular cell adhesion. J Am Soc Nephrol 2002 2.02
11 Osteoblastic 11beta-hydroxysteroid dehydrogenase type 1 activity increases with age and glucocorticoid exposure. J Bone Miner Res 2002 1.94
12 Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in pancreatic islets. J Steroid Biochem Mol Biol 2004 1.89
13 Vitamin D and placental-decidual function. J Soc Gynecol Investig 2004 1.79
14 IL-15 links TLR2/1-induced macrophage differentiation to the vitamin D-dependent antimicrobial pathway. J Immunol 2008 1.79
15 Vitamin D-binding protein directs monocyte responses to 25-hydroxy- and 1,25-dihydroxyvitamin D. J Clin Endocrinol Metab 2010 1.72
16 Vitamin D in defense of the human immune response. Ann N Y Acad Sci 2007 1.63
17 Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency. Nat Genet 2003 1.58
18 Autocrine metabolism of vitamin D in normal and malignant breast tissue. Clin Cancer Res 2005 1.58
19 Effects of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on cytokine production by human decidual cells. Biol Reprod 2006 1.57
20 Divergence of macrophage phagocytic and antimicrobial programs in leprosy. Cell Host Microbe 2009 1.55
21 Vitamin D deficiency in mice impairs colonic antibacterial activity and predisposes to colitis. Endocrinology 2010 1.51
22 1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients. J Alzheimers Dis 2009 1.51
23 Rare causes of calcitriol-mediated hypercalcemia: a case report and literature review. J Clin Endocrinol Metab 2010 1.48
24 Biological actions of extra-renal 25-hydroxyvitamin D-1alpha-hydroxylase and implications for chemoprevention and treatment. J Steroid Biochem Mol Biol 2005 1.45
25 Vitamin D deficiency modulates Graves' hyperthyroidism induced in BALB/c mice by thyrotropin receptor immunization. Endocrinology 2008 1.45
26 Altered endocrine and autocrine metabolism of vitamin D in a mouse model of gastrointestinal inflammation. Endocrinology 2008 1.44
27 T-cell cytokines differentially control human monocyte antimicrobial responses by regulating vitamin D metabolism. Proc Natl Acad Sci U S A 2010 1.42
28 The ontogeny of 25-hydroxyvitamin D(3) 1alpha-hydroxylase expression in human placenta and decidua. Am J Pathol 2002 1.41
29 Vitamin D: beyond bone. Ann N Y Acad Sci 2013 1.39
30 The aldo-keto reductase AKR1C3 is a novel suppressor of cell differentiation that provides a plausible target for the non-cyclooxygenase-dependent antineoplastic actions of nonsteroidal anti-inflammatory drugs. Cancer Res 2003 1.38
31 Reduction of the vitamin D hormonal system in kidney disease is associated with increased renal inflammation. Kidney Int 2008 1.36
32 Alternative splicing of vitamin D-24-hydroxylase: a novel mechanism for the regulation of extrarenal 1,25-dihydroxyvitamin D synthesis. J Biol Chem 2005 1.26
33 25-hydroxyvitamin D(3)-1alpha-hydroxylase expression in normal and pathological parathyroid glands. J Clin Endocrinol Metab 2002 1.24
34 Back to the future: a new look at 'old' vitamin D. J Endocrinol 2008 1.20
35 Fibroblast growth factor 23 inhibits extrarenal synthesis of 1,25-dihydroxyvitamin D in human monocytes. J Bone Miner Res 2013 1.17
36 Differential expression, function and response to inflammatory stimuli of 11beta-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation. Arthritis Res Ther 2006 1.17
37 Increased expression of 25-hydroxyvitamin D-1alpha-hydroxylase in dysgerminomas: a novel form of humoral hypercalcemia of malignancy. Am J Pathol 2004 1.17
38 Vitamin D and the regulation of placental inflammation. J Immunol 2011 1.13
39 Vitamin D metabolism and innate immunity. Mol Cell Endocrinol 2011 1.11
40 Heterogeneous nuclear ribonucleoprotein (hnRNP) binding to hormone response elements: a cause of vitamin D resistance. Proc Natl Acad Sci U S A 2003 1.06
41 Gene targeting by the vitamin D response element binding protein reveals a role for vitamin D in osteoblast mTOR signaling. FASEB J 2010 1.05
42 Suppression of iron-regulatory hepcidin by vitamin D. J Am Soc Nephrol 2013 1.03
43 Renal TLR4 mRNA expression correlates with inflammatory marker MCP-1 and profibrotic molecule TGF-β₁ in patients with chronic kidney disease. Nephron Clin Pract 2011 1.00
44 Increased expression of mineralocorticoid effector mechanisms in kidney biopsies of patients with heavy proteinuria. Circulation 2005 0.99
45 Identification of VDR-responsive gene signatures in breast cancer cells. Oncology 2007 0.99
46 Response element binding proteins and intracellular vitamin D binding proteins: novel regulators of vitamin D trafficking, action and metabolism. J Steroid Biochem Mol Biol 2004 0.99
47 Cross-sectional analysis of abnormalities of mineral homeostasis, vitamin D and parathyroid hormone in a cohort of pre-dialysis patients. The chronic renal impairment in Birmingham (CRIB) study. Nephron Clin Pract 2007 0.98
48 Prereceptor regulation of glucocorticoid action by 11beta-hydroxysteroid dehydrogenase: a novel determinant of cell proliferation. FASEB J 2002 0.97
49 Vitamin D binding protein and monocyte response to 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D: analysis by mathematical modeling. PLoS One 2012 0.97
50 A switch in dehydrogenase to reductase activity of 11 beta-hydroxysteroid dehydrogenase type 1 upon differentiation of human omental adipose stromal cells. J Clin Endocrinol Metab 2002 0.97
51 Hormone response element binding proteins: novel regulators of vitamin D and estrogen signaling. Steroids 2011 0.95
52 Expression of 11beta-hydroxysteroid dehydrogenase type 1 permits regulation of glucocorticoid bioavailability by human dendritic cells. Blood 2005 0.95
53 Vitamin D bioavailability and catabolism in pediatric chronic kidney disease. Pediatr Nephrol 2013 0.94
54 11Beta-hydroxysteroid dehydrogenase type 1 in differentiating omental human preadipocytes: from de-activation to generation of cortisol. Endocr Res 2002 0.92
55 Down-regulation of vitamin D receptor in mammospheres: implications for vitamin D resistance in breast cancer and potential for combination therapy. PLoS One 2013 0.91
56 Vitamin D activation of functionally distinct regulatory miRNAs in primary human osteoblasts. J Bone Miner Res 2013 0.91
57 Functional characterization of heterogeneous nuclear ribonuclear protein C1/C2 in vitamin D resistance: a novel response element-binding protein. J Biol Chem 2006 0.91
58 Substrate and enzyme trafficking as a means of regulating 1,25-dihydroxyvitamin D synthesis and action: the human innate immune response. J Bone Miner Res 2007 0.91
59 Dietary vitamin D restriction in pregnant female mice is associated with maternal hypertension and altered placental and fetal development. Endocrinology 2013 0.90
60 Inflammatory regulation of glucocorticoid metabolism in mesenchymal stromal cells. Arthritis Rheum 2012 0.89
61 Androgen receptor-mediated regulation of the alpha-subunit of the epithelial sodium channel in human kidney. Hypertension 2005 0.89
62 1alpha-hydroxylase and innate immune responses to 25-hydroxyvitamin D in colonic cell lines. J Steroid Biochem Mol Biol 2010 0.88
63 Vitamin D-mediated hypercalcemia in slack skin disease: evidence for involvement of extrarenal 25-hydroxyvitamin D 1alpha-hydroxylase. J Bone Miner Res 2006 0.88
64 Control of estradiol-directed gene transactivation by an intracellular estrogen-binding protein and an estrogen response element-binding protein. Mol Endocrinol 2007 0.86
65 Vitamin D: a new player in the world of mTOR signaling. Cell Cycle 2011 0.86
66 Late-onset apparent mineralocorticoid excess caused by novel compound heterozygous mutations in the HSD11B2 gene. Hypertension 2003 0.85
67 Immunomodulation by vitamin D: implications for TB. Expert Rev Clin Pharmacol 2011 0.85
68 19-Nor-1,25(OH)2D2 (a novel, noncalcemic vitamin D analogue), combined with arsenic trioxide, has potent antitumor activity against myeloid leukemia. Cancer Res 2005 0.85
69 11beta-hydroxysteroid dehydrogenase type 1 activity predicts the effects of glucocorticoids on bone. J Clin Endocrinol Metab 2003 0.84
70 Glucocorticoid-induced apoptosis in human decidua: a novel role for 11beta-hydroxysteroid dehydrogenase in late gestation. J Endocrinol 2007 0.83
71 Serum- and glucocorticoid-regulated kinase isoform-1 and epithelial sodium channel subunits in human ocular ciliary epithelium. Invest Ophthalmol Vis Sci 2003 0.83
72 Vitamin D and microRNAs in bone. Crit Rev Eukaryot Gene Expr 2013 0.83
73 Dietary vitamin D intake in advanced CKD/ESRD. Semin Dial 2010 0.82
74 Hormones and immune function: implications of aging. Aging Cell 2004 0.82
75 Dynamic development of glucocorticoid resistance during autoimmune neuroinflammation. J Clin Endocrinol Metab 2012 0.81
76 Beyond mineral metabolism, is there an interplay between FGF23 and vitamin D in innate immunity? Pediatr Nephrol 2012 0.80
77 Association studies between the HSD11B2 gene (encoding human 11beta-hydroxysteroid dehydrogenase type 2), type 1 diabetes mellitus and diabetic nephropathy. Eur J Endocrinol 2002 0.80
78 An Hsp27-related, dominant-negative-acting intracellular estradiol-binding protein. J Biol Chem 2004 0.79
79 Estradiol and tamoxifen mediate rescue of the dominant-negative effects of estrogen response element-binding protein in vivo and in vitro. Endocrinology 2008 0.79
80 Mechanisms of decreased Vitamin D 1alpha-hydroxylase activity in prostate cancer cells. Mol Cell Endocrinol 2004 0.79
81 Cloning of a functional 25-hydroxyvitamin D-1α-hydroxylase in zebrafish (Danio rerio). Cell Biochem Funct 2014 0.78
82 Expression of renal 11beta-hydroxysteroid dehydrogenase type 2 is decreased in patients with impaired renal function. Eur J Endocrinol 2005 0.77
83 Adenosine 5'-triphosphate-dependent vitamin D sterol binding to heat shock protein-70 chaperones. Endocrinology 2005 0.77
84 Report of the CCFA pediatric bone, growth and muscle health workshop, New York City, November 11-12, 2011, with updates. Inflamm Bowel Dis 2013 0.77
85 Vitamin D-mediated hypercalcemia and Cushing syndrome as manifestations of malignant pleural mesothelioma. Endocr Pract 2008 0.77
86 Renal PPARγ mRNA expression increases with impairment of renal function in patients with chronic kidney disease. Nephrology (Carlton) 2010 0.77
87 Hypercalcemia associated with mineral oil-induced sclerosing paraffinomas. Endocr Pract 2013 0.76
88 A role for vitamin D in placental immunology. J Infect Dis 2010 0.75
89 Immunodetection of 11β-Hydroxysteroid Dehydrogenase Type 2 in Human Mineralocorticoid Target Tissues: Evidence for Nuclear Localization. Endocrinology 1997 0.75