Published in Yan Ke Xue Bao on December 01, 2006
Breakdown of the blood-ocular barrier as a strategy for the systemic use of nanosystems. Pharmaceutics (2012) 0.76
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
The diploid genome sequence of an Asian individual. Nature (2008) 46.29
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Interventions for preventing obesity in children. Cochrane Database Syst Rev (2011) 8.81
Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders. Proc Natl Acad Sci U S A (2010) 3.78
Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human. Proc Natl Acad Sci U S A (2005) 3.37
A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with susceptibility to multiple cancers. Nat Genet (2007) 2.98
Genetic evidence supports demic diffusion of Han culture. Nature (2004) 2.92
Inertial aided cycle slip detection and identification for integrated PPP GPS and INS. Sensors (Basel) (2012) 2.39
Electric fans for reducing adverse health impacts in heatwaves. Cochrane Database Syst Rev (2012) 2.35
SCN8A mutations in Chinese children with early onset epilepsy and intellectual disability. Epilepsia (2015) 2.17
Prognostic value of coronary CT angiography and calcium score for major adverse cardiac events in outpatients. JACC Cardiovasc Imaging (2012) 2.17
Bietti crystalline corneoretinal dystrophy is caused by mutations in the novel gene CYP4V2. Am J Hum Genet (2004) 2.13
A cocaine hydrolase engineered from human butyrylcholinesterase selectively blocks cocaine toxicity and reinstatement of drug seeking in rats. Neuropsychopharmacology (2008) 2.07
Mutations in betaB3-crystallin associated with autosomal recessive cataract in two Pakistani families. Invest Ophthalmol Vis Sci (2005) 1.94
Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development. Dev Biol (2009) 1.73
Laboratory diagnosis of four recent sporadic cases of community-acquired SARS, Guangdong Province, China. Emerg Infect Dis (2004) 1.65
Efficacy and safety of mesenchymal stromal cell treatment from related donors for patients with refractory aplastic anemia. Cytotherapy (2013) 1.48
Molecular mechanisms associated with Angiotensin-converting enzyme-inhibitory peptide activity on vascular extracellular matrix remodeling. Cardiology (2014) 1.45
Addressing disparities in children's health in China. Arch Dis Child (2008) 1.44
The nonspecific anti-inflammatory therapy with methotrexate for patients with chronic heart failure. Am Heart J (2006) 1.44
Clinical patterns and characteristics of uveitis in a tertiary center for uveitis in China. Curr Eye Res (2005) 1.41
Confirmation and refinement of an autosomal dominant congenital motor nystagmus locus in chromosome 1q31.3-q32.1. J Hum Genet (2012) 1.38
A new locus for autosomal recessive nuclear cataract mapped to chromosome 19q13 in a Pakistani family. Invest Ophthalmol Vis Sci (2005) 1.34
Detection of variants in 15 genes in 87 unrelated Chinese patients with Leber congenital amaurosis. PLoS One (2011) 1.33
PseAAC-Builder: a cross-platform stand-alone program for generating various special Chou's pseudo-amino acid compositions. Anal Biochem (2012) 1.29
Mitochondrial DNA haplogroups M7b1'2 and M8a affect clinical expression of leber hereditary optic neuropathy in Chinese families with the m.11778G-->a mutation. Am J Hum Genet (2008) 1.29
Iterative image reconstruction for cerebral perfusion CT using a pre-contrast scan induced edge-preserving prior. Phys Med Biol (2012) 1.27
Estimation and uncertainty analysis of impacts of future heat waves on mortality in the eastern United States. Environ Health Perspect (2013) 1.27
Identification of CYP4V2 mutation in 21 families and overview of mutation spectrum in Bietti crystalline corneoretinal dystrophy. Biochem Biophys Res Commun (2011) 1.26
Functions of the intermediate filament cytoskeleton in the eye lens. J Clin Invest (2009) 1.26
Genetic variants at 13q12.12 are associated with high myopia in the Han Chinese population. Am J Hum Genet (2011) 1.23
Optimal lens epithelial cell proliferation is dependent on the connexin isoform providing gap junctional coupling. Invest Ophthalmol Vis Sci (2007) 1.19
An unusual haplotype structure on human chromosome 8p23 derived from the inversion polymorphism. Hum Mutat (2008) 1.19
Association of the single nucleotide polymorphisms in the extracellular matrix metalloprotease-9 gene with PACG in southern China. Mol Vis (2009) 1.16
Haplotypes in matrix metalloproteinase gene cluster on chromosome 11q22 contribute to the risk of lung cancer development and progression. Clin Cancer Res (2006) 1.16
Mutations of 60 known causative genes in 157 families with retinitis pigmentosa based on exome sequencing. Hum Genet (2014) 1.13
TGFβ inhibition enhances the generation of hematopoietic progenitors from human ES cell-derived hemogenic endothelial cells using a stepwise strategy. Cell Res (2011) 1.12
Predicting folding free energy changes upon single point mutations. Bioinformatics (2012) 1.12
Cardioprotective effects and underlying mechanisms of oxymatrine against Ischemic myocardial injuries of rats. Phytother Res (2008) 1.12
Effects of cocaine hydrolase on cocaine self-administration under a PR schedule and during extended access (escalation) in rats. Psychopharmacology (Berl) (2010) 1.11
Modeling insurer-homeowner interactions in managing natural disaster risk. Risk Anal (2014) 1.11
Remote perconditioning reduces myocardial injury in adult valve replacement: a randomized controlled trial. J Surg Res (2010) 1.11
Mutation analysis of 12 genes in Chinese families with congenital cataracts. Mol Vis (2011) 1.10
Insights into diterpene cyclization from structure of bifunctional abietadiene synthase from Abies grandis. J Biol Chem (2012) 1.09
Clusters of sudden unexplained death associated with the mushroom, Trogia venenata, in rural Yunnan Province, China. PLoS One (2012) 1.09
Endoscopic versus microscopic transsphenoidal pituitary adenoma surgery: a meta-analysis. World J Surg Oncol (2014) 1.09
Combined cocaine hydrolase gene transfer and anti-cocaine vaccine synergistically block cocaine-induced locomotion. PLoS One (2012) 1.08
Genetic structure of Hmong-Mien speaking populations in East Asia as revealed by mtDNA lineages. Mol Biol Evol (2004) 1.07
Pathogenic role of diabetes-induced PPAR-α down-regulation in microvascular dysfunction. Proc Natl Acad Sci U S A (2013) 1.07
Gene transfer of mutant mouse cholinesterase provides high lifetime expression and reduced cocaine responses with no evident toxicity. PLoS One (2013) 1.06
Molecular epidemiology of mtDNA mutations in 903 Chinese families suspected with Leber hereditary optic neuropathy. J Hum Genet (2006) 1.06
Cocaine hydrolase encoded in viral vector blocks the reinstatement of cocaine seeking in rats for 6 months. Biol Psychiatry (2011) 1.05
Discovery and validation of prognostic markers in gastric cancer by genome-wide expression profiling. World J Gastroenterol (2011) 1.05
Novel GPR143 mutations and clinical characteristics in six Chinese families with X-linked ocular albinism. Mol Vis (2008) 1.04
Roles of Bmp4 during tooth morphogenesis and sequential tooth formation. Development (2013) 1.04
High myopia is not associated with the SNPs in the TGIF, lumican, TGFB1, and HGF genes. Invest Ophthalmol Vis Sci (2008) 1.02
Novel SOX2 mutation associated with ocular coloboma in a Chinese family. Arch Ophthalmol (2008) 1.02
Cinnamic acid pretreatment mitigates chilling stress of cucumber leaves through altering antioxidant enzyme activity. J Plant Physiol (2011) 1.02
Inhibition of tumor metastasis by a growth factor receptor bound protein 2 Src homology 2 domain-binding antagonist. Cancer Res (2007) 1.01
Sequence-dependent DNA immobilization: specific versus nonspecific contributions. Langmuir (2004) 1.01
Investigation of CYP1B1 mutations in Chinese patients with primary congenital glaucoma. Mol Vis (2009) 1.01
Replication study supports CTNND2 as a susceptibility gene for high myopia. Invest Ophthalmol Vis Sci (2011) 1.01
δEF1 promotes osteolytic metastasis of MDA-MB-231 breast cancer cells by regulating MMP-1 expression. Biochim Biophys Acta (2011) 1.00
Autosomal recessive retinitis pigmentosa is associated with mutations in RP1 in three consanguineous Pakistani families. Invest Ophthalmol Vis Sci (2005) 1.00
Population density and refractive error among Chinese children. Invest Ophthalmol Vis Sci (2010) 1.00
CC chemokine ligand 25 enhances resistance to apoptosis in CD4+ T cells from patients with T-cell lineage acute and chronic lymphocytic leukemia by means of livin activation. Cancer Res (2004) 1.00
Screening for markers of frailty and perceived risk of adverse outcomes using the Risk Instrument for Screening in the Community (RISC). BMC Geriatr (2014) 1.00
Silibinin inhibits β-catenin/ZEB1 signaling and suppresses bladder cancer metastasis via dual-blocking epithelial-mesenchymal transition and stemness. Cell Signal (2013) 1.00
The investigation of 125I seed implantation as a salvage modality for unresectable pancreatic carcinoma. J Exp Clin Cancer Res (2013) 0.99
Attitudes of students, parents, and teachers toward glasses use in rural China. Arch Ophthalmol (2010) 0.98
Clinical and linkage study on a consanguineous Chinese family with autosomal recessive high myopia. Mol Vis (2009) 0.98
Effects of ambient air pollution on lung function growth in Chinese schoolchildren. Respir Med (2010) 0.98
Iris hyperpigmentation in a Chinese family with ocular albinism and the GPR143 mutation. Am J Med Genet A (2009) 0.98
Risk-association of DNA methyltransferases polymorphisms with gastric cancer in the Southern Chinese population. Int J Mol Sci (2012) 0.97
Online selective kernel-based temporal difference learning. IEEE Trans Neural Netw Learn Syst (2013) 0.97
Mutations in the gene encoding the alpha-subunit of rod phosphodiesterase in consanguineous Pakistani families. Mol Vis (2006) 0.97
Respiratory health in overweight and obese Chinese children. Pediatr Pulmonol (2009) 0.96
Novel TSPAN12 mutations in patients with familial exudative vitreoretinopathy and their associated phenotypes. Mol Vis (2011) 0.96
Protective effects of tetramethylpyrazine on rat retinal cell cultures. Neurochem Int (2007) 0.96
The de-ubiquitinylating enzyme, USP2, is associated with the circadian clockwork and regulates its sensitivity to light. PLoS One (2011) 0.96
Mutation spectrum and frequency of the RHO gene in 248 Chinese families with retinitis pigmentosa. Biochem Biophys Res Commun (2010) 0.96
Mitochondrial DNA haplogroup background affects LHON, but not suspected LHON, in Chinese patients. PLoS One (2011) 0.96
Strikingly different penetrance of LHON in two Chinese families with primary mutation G11778A is independent of mtDNA haplogroup background and secondary mutation G13708A. Mutat Res (2008) 0.96
Physical activity, cardiorespiratory fitness, and obesity among Chinese children. Prev Med (2010) 0.95
Anti-cocaine antibody and butyrylcholinesterase-derived cocaine hydrolase exert cooperative effects on cocaine pharmacokinetics and cocaine-induced locomotor activity in mice. Chem Biol Interact (2012) 0.95
Inhibition of angiogenesis by growth factor receptor bound protein 2-Src homology 2 domain bound antagonists. Mol Cancer Ther (2004) 0.95
Intracranial choriocarcinoma occurrence in males: Two cases and a review of the literature. Oncol Lett (2013) 0.95
Commercially activated carbon as the source for producing multicolor photoluminescent carbon dots by chemical oxidation. Chem Commun (Camb) (2010) 0.95
Effect of an integrated control strategy for schistosomiasis japonica in the lower reaches of the Yangtze River, China: an evaluation from 2005 to 2008. Parasit Vectors (2011) 0.95
Dynamic modeling of human 5-lipoxygenase-inhibitor interactions helps to discover novel inhibitors. J Med Chem (2012) 0.94
Visual morbidity due to inaccurate spectacles among school children in rural China: the See Well to Learn Well Project, report 1. Invest Ophthalmol Vis Sci (2009) 0.94
Relationship between human sperm-hyaluronan binding assay and fertilization rate in conventional in vitro fertilization. Hum Reprod (2006) 0.94
Cerulean cataract mapped to 12q13 and associated with a novel initiation codon mutation in MIP. Mol Vis (2011) 0.94
Content-based retrieval of brain tumor in contrast-enhanced MRI images using tumor margin information and learned distance metric. Med Phys (2012) 0.94
Tumor-inhibitory effect and immunomodulatory activity of fullerol C60(OH)x. Small (2008) 0.94
Osr2 acts downstream of Pax9 and interacts with both Msx1 and Pax9 to pattern the tooth developmental field. Dev Biol (2011) 0.94
KIF21A novel deletion and recurrent mutation in patients with congenital fibrosis of the extraocular muscles-1. Int J Mol Med (2011) 0.93
Performance comparison among the major healthcare financing systems in six cities of the Pearl River Delta region, mainland China. PLoS One (2012) 0.93