Published in Nat Genet on April 22, 2007
The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote. Nucleic Acids Res (2013) 4.45
Genetic susceptibility to breast cancer. Mol Oncol (2010) 2.52
Nature meets nurture: molecular genetics of gastric cancer. Hum Genet (2009) 1.87
Genetic susceptibility loci for breast cancer by estrogen receptor status. Clin Cancer Res (2008) 1.72
Caspases and cancer. Cell Death Differ (2011) 1.56
CANDID: a flexible method for prioritizing candidate genes for complex human traits. Genet Epidemiol (2008) 1.36
Genotypic variants at 2q33 and risk of esophageal squamous cell carcinoma in China: a meta-analysis of genome-wide association studies. Hum Mol Genet (2012) 1.28
RNA silencing of Mcl-1 enhances ABT-737-mediated apoptosis in melanoma: role for a caspase-8-dependent pathway. PLoS One (2009) 1.28
Genetic variants and haplotypes of the caspase-8 and caspase-10 genes contribute to susceptibility to cutaneous melanoma. Hum Mutat (2008) 1.22
A promoter polymorphism in the CASP8 gene is not associated with cancer risk. Nat Genet (2008) 1.18
CASP8 polymorphisms contribute to cancer susceptibility: evidence from a meta-analysis of 23 publications with 55 individual studies. Carcinogenesis (2010) 1.09
CASP8 variants D302H and -652 6N ins/del do not influence the risk of colorectal cancer in the United Kingdom population. Br J Cancer (2008) 1.06
A breast cancer risk haplotype in the caspase-8 gene. Cancer Res (2009) 1.03
Association of the variants CASP8 D302H and CASP10 V410I with breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers. Cancer Epidemiol Biomarkers Prev (2010) 1.01
Genetic determinants of phenotypic diversity in humans. Genome Biol (2008) 1.00
Caspase polymorphisms and genetic susceptibility to multiple myeloma. Hematol Oncol (2008) 0.98
The six-nucleotide deletion/insertion variant in the CASP8 promoter region is inversely associated with risk of squamous cell carcinoma of the head and neck. Cancer Prev Res (Phila) (2010) 0.98
Population-specific genetic associations with oesophageal squamous cell carcinoma in South Africa. Carcinogenesis (2011) 0.96
Polymorphisms of caspase 8 and caspase 9 gene and colorectal cancer susceptibility and prognosis. Int J Colorectal Dis (2011) 0.96
Autism-associated haplotype affects the regulation of the homeobox gene, ENGRAILED 2. Biol Psychiatry (2009) 0.95
Effects of PON polymorphisms and haplotypes on molecular phenotype in Mexican-American mothers and children. Environ Mol Mutagen (2011) 0.94
Fine-mapping CASP8 risk variants in breast cancer. Cancer Epidemiol Biomarkers Prev (2011) 0.94
A SNP in the HSP90AA1 gene 5' flanking region is associated with the adaptation to differential thermal conditions in the ovine species. Cell Stress Chaperones (2009) 0.93
Research status and funding trends of lung cancer biomarkers. J Thorac Dis (2013) 0.93
A comprehensive review on host genetic susceptibility to human papillomavirus infection and progression to cervical cancer. Indian J Hum Genet (2011) 0.92
Polymorphisms and haplotypes in the caspase-3, caspase-7, and caspase-8 genes and risk for endometrial cancer: a population-based, case-control study in a Chinese population. Cancer Epidemiol Biomarkers Prev (2009) 0.91
CASP3 polymorphisms and risk of squamous cell carcinoma of the head and neck. Clin Cancer Res (2008) 0.90
Mammary cancer susceptibility: human genes and rodent models. Mamm Genome (2007) 0.88
Insertion/deletion polymorphisms in the ΔNp63 promoter are a risk factor for bladder exstrophy epispadias complex. PLoS Genet (2012) 0.87
A small molecule SMAC mimic LBW242 potentiates TRAIL- and anticancer drug-mediated cell death of ovarian cancer cells. PLoS One (2012) 0.87
Linkage to chromosome 2q32.2-q33.3 in familial serrated neoplasia (Jass syndrome). Fam Cancer (2011) 0.87
New basal cell carcinoma susceptibility loci. Nat Commun (2015) 0.87
The immune system in the pathogenesis of ovarian cancer. Crit Rev Immunol (2013) 0.86
Gene polymorphisms, apoptotic capacity and cancer risk. Hum Genet (2009) 0.86
A functional variant at the miR-885-5p binding site of CASP3 confers risk of both index and second primary malignancies in patients with head and neck cancer. FASEB J (2012) 0.85
Caspase-8 polymorphisms result in reduced Alemtuzumab-induced T-cell apoptosis and worse survival after transplantation. Bone Marrow Transplant (2014) 0.85
Association between CASP8 and CASP10 polymorphisms and toxicity outcomes with platinum-based chemotherapy in Chinese patients with non-small cell lung cancer. Oncologist (2012) 0.85
Combined effects of E2F1 and E2F2 polymorphisms on risk and early onset of squamous cell carcinoma of the head and neck. Mol Carcinog (2012) 0.84
Caspase 8 and caspase 9 gene polymorphisms and susceptibility to gastric cancer. Gastric Cancer (2011) 0.83
Association of ATM Gene Polymorphism with PTC Metastasis in Female Patients. Int J Endocrinol (2014) 0.83
Genetic polymorphisms of the CASP8 gene promoter may not be associated with colorectal cancer in Han Chinese from southwest China. PLoS One (2013) 0.83
The pattern of insertion/deletion polymorphism in Arabidopsis thaliana. Mol Genet Genomics (2008) 0.83
Impact of human pathogenic micro-insertions and micro-deletions on post-transcriptional regulation. Hum Mol Genet (2014) 0.81
Association of CASP8 D302H polymorphism with reduced risk of aggressive prostate carcinoma. Prostate (2010) 0.80
Polymorphisms and a haplotype in heparanase gene associations with the progression and prognosis of gastric cancer in a northern Chinese population. PLoS One (2012) 0.79
Role of a novel functional variant in the PPP2R1A promoter on the regulation of PP2A-Aalpha and the risk of hepatocellular carcinoma. PLoS One (2013) 0.79
CASP8 -652 6N del polymorphism contributes to colorectal cancer susceptibility: evidence from a meta-analysis. PLoS One (2014) 0.78
A six-nucleotide deletion polymorphism in the casp8 promoter is associated with reduced risk of esophageal and gastric cancers in Kashmir valley. Indian J Hum Genet (2011) 0.78
Identification of a secondary promoter of CASP8 and its related transcription factor PURα. Int J Oncol (2014) 0.77
Genetic variation and its role in malignancy. Int J Biomed Sci (2011) 0.77
Molecular response and association analysis of Megalobrama amblycephala fih-1 with hypoxia. Mol Genet Genomics (2016) 0.76
Association between CASP8 -652 6N del polymorphism (rs3834129) and colorectal cancer risk: results from a multi-centric study. PLoS One (2014) 0.76
Prognostic Impact of Polymorphisms in the CASPASE Genes on Survival of Patients with Colorectal Cancer. Cancer Res Treat (2012) 0.75
Association of CASP9, CASP10 gene polymorphisms and tea drinking with colorectal cancer risk in the Han Chinese population. J Zhejiang Univ Sci B (2013) 0.75
A functional 12T-insertion polymorphism in the ATP1A1 promoter confers decreased susceptibility to hypertension in a male Sardinian population. PLoS One (2015) 0.75
Influence of Genetic Ancestry on INDEL Markers of NFKβ1, CASP8, PAR1, IL4 and CYP19A1 Genes in Leprosy Patients. PLoS Negl Trop Dis (2015) 0.75
Prognostic relevance of caspase 8 -652 6N InsDel and Asp302His polymorphisms for breast cancer. BMC Cancer (2016) 0.75
Association of NCOA3 polymorphisms with Dyslipidemia in the Chinese Han population. Lipids Health Dis (2015) 0.75
Glioma Association and Balancing Selection of ZFPM2. PLoS One (2015) 0.75
CASP-8 -652 6N ins/del polymorphism and cancer risk: A literature-based systematic HuGE review and meta-analysis. Exp Ther Med (2012) 0.75
Caspase-8 polymorphisms and risk of oral squamous cell carcinoma. Exp Ther Med (2015) 0.75
Effect of human papillomavirus seropositivity and E2F2 promoter variants on risk of squamous cell carcinomas of oropharynx and oral cavity. Carcinogenesis (2016) 0.75
CASP8 -652 6N insertion/deletion polymorphism and overall cancer risk: evidence from 49 studies. Oncotarget (2017) 0.75
Polymorphism rs189037C > T in the promoter region of the ATM gene may associate with reduced risk of T2DM in older adults in China: a case control study. BMC Med Genet (2017) 0.75
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
The diploid genome sequence of an Asian individual. Nature (2008) 46.29
Integrating common and rare genetic variation in diverse human populations. Nature (2010) 32.30
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Interventions for preventing obesity in children. Cochrane Database Syst Rev (2011) 8.81
The Genomes of Oryza sativa: a history of duplications. PLoS Biol (2005) 7.67
A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms. Nature (2004) 5.24
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases. EMBO Rep (2011) 4.89
Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis. J Clin Invest (2003) 4.08
Genome-wide association study identifies 1p36.22 as a new susceptibility locus for hepatocellular carcinoma in chronic hepatitis B virus carriers. Nat Genet (2010) 4.01
Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data. Proc Natl Acad Sci U S A (2011) 3.80
Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders. Proc Natl Acad Sci U S A (2010) 3.78
Digital signaling and hysteresis characterize ras activation in lymphoid cells. Cell (2009) 3.47
Circulating microRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis. Mol Carcinog (2010) 3.44
Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human. Proc Natl Acad Sci U S A (2005) 3.37
Genetic evidence supports demic diffusion of Han culture. Nature (2004) 2.92
A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese. Nat Genet (2011) 2.85
Predictive value of serum uric acid levels on mortality in acute coronary syndrome patients with chronic kidney disease after drug-eluting stent implantation. Cardiology (2013) 2.64
Fen1 mutations result in autoimmunity, chronic inflammation and cancers. Nat Med (2007) 2.48
Effect of tumor microenvironment modulation on the efficacy of oncolytic virus therapy. J Natl Cancer Inst (2007) 2.46
Inertial aided cycle slip detection and identification for integrated PPP GPS and INS. Sensors (Basel) (2012) 2.39
Electric fans for reducing adverse health impacts in heatwaves. Cochrane Database Syst Rev (2012) 2.35
Self-assembly of self-limiting monodisperse supraparticles from polydisperse nanoparticles. Nat Nanotechnol (2011) 2.34
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Nat Genet (2012) 2.26
Polymorphisms of death pathway genes FAS and FASL in esophageal squamous-cell carcinoma. J Natl Cancer Inst (2004) 2.22
SCN8A mutations in Chinese children with early onset epilepsy and intellectual disability. Epilepsia (2015) 2.17
Prognostic value of coronary CT angiography and calcium score for major adverse cardiac events in outpatients. JACC Cardiovasc Imaging (2012) 2.17
A cocaine hydrolase engineered from human butyrylcholinesterase selectively blocks cocaine toxicity and reinstatement of drug seeking in rats. Neuropsychopharmacology (2008) 2.07
Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations. Nat Genet (2011) 2.05
Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma. J Exp Med (2002) 2.04
Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. Nat Genet (2012) 2.00
A prospective randomized equivalence trial of the GlideScope Cobalt® video laryngoscope to traditional direct laryngoscopy in neonates and infants. Anesthesiology (2012) 2.00
A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1. Nat Genet (2011) 1.98
Genetic variants on chromosome 15q25 associated with lung cancer risk in Chinese populations. Cancer Res (2009) 1.94
The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia. PLoS Genet (2010) 1.90
Influence of patient and hospital characteristics on anesthesia time in medicare patients undergoing general and orthopedic surgery. Anesthesiology (2007) 1.87
GWAS identifies novel susceptibility loci on 6p21.32 and 21q21.3 for hepatocellular carcinoma in chronic hepatitis B virus carriers. PLoS Genet (2012) 1.86
Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier. Proc Natl Acad Sci U S A (2009) 1.86
Detection of PCC functional connectivity characteristics in resting-state fMRI in mild Alzheimer's disease. Behav Brain Res (2008) 1.83
Microparticles initiate decompression-induced neutrophil activation and subsequent vascular injuries. J Appl Physiol (1985) (2010) 1.78
Biocontrol of Listeria monocytogenes on fresh-cut produce by treatment with lytic bacteriophages and a bacteriocin. Appl Environ Microbiol (2003) 1.75
Community engagement and informed consent in the International HapMap project. Community Genet (2007) 1.73
Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development. Dev Biol (2009) 1.73
Polymorphisms in DNA base excision repair genes ADPRT and XRCC1 and risk of lung cancer. Cancer Res (2005) 1.69
Establishment of clonal colony-forming assay for propagation of pancreatic cancer cells with stem cell properties. Pancreas (2007) 1.68
Identification of functional genetic variants in cyclooxygenase-2 and their association with risk of esophageal cancer. Gastroenterology (2005) 1.67
Genome-wide association study of survival in patients with pancreatic adenocarcinoma. Gut (2012) 1.66
Laboratory diagnosis of four recent sporadic cases of community-acquired SARS, Guangdong Province, China. Emerg Infect Dis (2004) 1.65
Identification of genetic variants in base excision repair pathway and their associations with risk of esophageal squamous cell carcinoma. Cancer Res (2004) 1.64
Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. Nat Genet (2012) 1.64
3D convolutional neural networks for human action recognition. IEEE Trans Pattern Anal Mach Intell (2013) 1.62
Immunopathogenesis of experimental ulcerative colitis is mediated by eosinophil peroxidase. J Immunol (2004) 1.62
Aurora-A/STK15 T+91A is a general low penetrance cancer susceptibility gene: a meta-analysis of multiple cancer types. Carcinogenesis (2005) 1.61
Genetic polymorphisms of interleukin (IL)-1B, IL-1RN, IL-8, IL-10 and tumor necrosis factor {alpha} and risk of gastric cancer in a Chinese population. Carcinogenesis (2004) 1.57
The role of P53 and MDM2 polymorphisms in the risk of esophageal squamous cell carcinoma. Cancer Res (2005) 1.56
Expression differences of circulating microRNAs in metastatic castration resistant prostate cancer and low-risk, localized prostate cancer. Prostate (2012) 1.54
Retracted Universal primers for HBV genome DNA amplification across subtypes: a case study for designing more effective viral primers. Virol J (2007) 1.54
Expression of class III beta-tubulin reduces microtubule assembly and confers resistance to paclitaxel. Cell Motil Cytoskeleton (2003) 1.50
Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population. Nat Genet (2012) 1.49
Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer. Hum Mutat (2006) 1.49
Efficacy and safety of mesenchymal stromal cell treatment from related donors for patients with refractory aplastic anemia. Cytotherapy (2013) 1.48
Isolation and identification of cancer stem-like cells in esophageal carcinoma cell lines. Stem Cells Dev (2009) 1.47
Analysis of the complications induced by polyacrylamide hydrogel injection. Plast Reconstr Surg (2004) 1.47
Regulation of microRNA by antagomirs: a new class of pharmacological antagonists for the specific regulation of gene function? Am J Respir Cell Mol Biol (2006) 1.47
Functional haplotypes in the promoter of matrix metalloproteinase-2 predict risk of the occurrence and metastasis of esophageal cancer. Cancer Res (2004) 1.46
Aortic valve cyclic stretch causes increased remodeling activity and enhanced serotonin receptor responsiveness. Ann Thorac Surg (2011) 1.46
Molecular mechanisms associated with Angiotensin-converting enzyme-inhibitory peptide activity on vascular extracellular matrix remodeling. Cardiology (2014) 1.45
Genetic polymorphisms and susceptibility to esophageal cancer among Chinese population (review). Oncol Rep (2003) 1.45