John C Atherton

Author PubWeight™ 50.28‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Helicobacter pylori persistence: biology and disease. J Clin Invest 2004 4.75
2 A new Helicobacter pylori vacuolating cytotoxin determinant, the intermediate region, is associated with gastric cancer. Gastroenterology 2007 3.54
3 Clinical relevance of Helicobacter pylori cagA and vacA gene polymorphisms. Gastroenterology 2008 2.63
4 Determinants and consequences of different levels of CagA phosphorylation for clinical isolates of Helicobacter pylori. Gastroenterology 2004 2.40
5 Helicobacter pylori dupA is polymorphic, and its active form induces proinflammatory cytokine secretion by mononuclear cells. J Infect Dis 2010 1.89
6 Differences in virulence markers between Helicobacter pylori strains from Iraq and those from Iran: potential importance of regional differences in H. pylori-associated disease. J Clin Microbiol 2008 1.84
7 Helicobacter pylori binds von Willebrand factor and interacts with GPIb to induce platelet aggregation. Gastroenterology 2003 1.69
8 Determinants of non-toxicity in the gastric pathogen Helicobacter pylori. J Biol Chem 2003 1.51
9 Functional association between the Helicobacter pylori virulence factors VacA and CagA. J Med Microbiol 2008 1.44
10 The inflammatory and immune response to Helicobacter pylori infection. Best Pract Res Clin Gastroenterol 2007 1.35
11 Nucleotide-binding oligomerization domain-1 and epidermal growth factor receptor: critical regulators of beta-defensins during Helicobacter pylori infection. J Biol Chem 2006 1.30
12 Simple method for determination of the number of Helicobacter pylori CagA variable-region EPIYA tyrosine phosphorylation motifs by PCR. J Clin Microbiol 2005 1.28
13 Differences in Helicobacter pylori CagA tyrosine phosphorylation motif patterns between western and East Asian strains, and influences on interleukin-8 secretion. J Med Microbiol 2008 1.21
14 The presence of dupA in Helicobacter pylori is not significantly associated with duodenal ulceration in Belgium, South Africa, China, or North America. Clin Infect Dis 2007 1.19
15 Helicobacter pylori stimulates dendritic cells to induce interleukin-17 expression from CD4+ T lymphocytes. Infect Immun 2009 1.15
16 Helicobacter pylori potentiates epithelial:mesenchymal transition in gastric cancer: links to soluble HB-EGF, gastrin and matrix metalloproteinase-7. Gut 2010 1.11
17 Genetic analysis of Helicobacter pylori strain populations colonizing the stomach at different times postinfection. J Bacteriol 2007 1.09
18 Helicobacter pylori induces gastric epithelial cell invasion in a c-Met and type IV secretion system-dependent manner. J Biol Chem 2006 1.05
19 Toxigenic Helicobacter pylori infection precedes gastric hypochlorhydria in cancer relatives, and H. pylori virulence evolves in these families. Clin Cancer Res 2008 1.05
20 Heterogeneity in the activity of Mexican Helicobacter pylori strains in gastric epithelial cells and its association with diversity in the cagA gene. Infect Immun 2007 0.99
21 Evolution of the Helicobacter pylori vacuolating cytotoxin in a human stomach. J Bacteriol 2004 0.94
22 cagA and vacA genotype of Helicobacter pylori associated with gastric diseases in Xi'an area. World J Gastroenterol 2003 0.92
23 Increased expression of the urokinase plasminogen activator system by Helicobacter pylori in gastric epithelial cells. Am J Physiol Gastrointest Liver Physiol 2008 0.89
24 Mastic gum has no effect on Helicobacter pylori load in vivo. J Antimicrob Chemother 2003 0.89
25 Helicobacter pylori supernatants cause epithelial cytoskeletal disruption that is bacterial strain and epithelial cell line dependent but not toxin VacA dependent. Infect Immun 2003 0.88
26 A novel method for genotyping the Helicobacter pylori vacA intermediate region directly in gastric biopsy specimens. J Clin Microbiol 2012 0.87
27 Tyrosine phosphorylation of CagA from Chinese Helicobacter pylori isolates in AGS gastric epithelial cells. J Clin Microbiol 2005 0.87
28 In Helicobacter pylori, LuxS is a key enzyme in cysteine provision through a reverse transsulfuration pathway. J Bacteriol 2010 0.87
29 The highly repetitive region of the Helicobacter pylori CagY protein comprises tandem arrays of an alpha-helical repeat module. J Mol Biol 2008 0.86
30 In Helicobacter pylori auto-inducer-2, but not LuxS/MccAB catalysed reverse transsulphuration, regulates motility through modulation of flagellar gene transcription. BMC Microbiol 2010 0.85
31 Helicobacter pylori-induced inhibition of vascular endothelial cell functions: a role for VacA-dependent nitric oxide reduction. Am J Physiol Heart Circ Physiol 2008 0.83
32 The effect of the human gut-signalling hormone, norepinephrine, on the growth of the gastric pathogen Helicobacter pylori. Helicobacter 2009 0.82
33 Paired cysteine residues are required for high levels of the Helicobacter pylori autotransporter VacA. Microbiology 2006 0.82
34 A study of age-specific Helicobacter pylori seropositivity rates in Iraq. Helicobacter 2008 0.81
35 A study of Helicobacter pylori-associated gastritis patterns in Iraq and their association with strain virulence. Saudi J Gastroenterol 2009 0.81
36 The clinical utility and diagnostic yield of routine gastric biopsies in the investigation of iron deficiency anemia: a case-control study. Am J Gastroenterol 2008 0.78
37 The effect of different strains of Helicobacter pylori on platelet aggregation. Can J Gastroenterol 2007 0.77
38 Brefeldin A enhances Helicobacter pylori vacuolating cytotoxin-induced vacuolation of epithelial cells. FEMS Microbiol Lett 2004 0.76
39 All subtypes of the cytotoxin VacA adsorb to the surface of Helicobacter pylori post-secretion. J Med Microbiol 2005 0.76
40 Human gastrin: a true growth factor for Helicobacter pylori? Helicobacter 2009 0.75