Published in J Med Microbiol on September 01, 2008
Helicobacter pylori and gastric cancer: factors that modulate disease risk. Clin Microbiol Rev (2010) 3.41
Coadaptation of Helicobacter pylori and humans: ancient history, modern implications. J Clin Invest (2009) 3.26
Role of innate immunity in Helicobacter pylori-induced gastric malignancy. Physiol Rev (2010) 1.73
Helicobacter pylori exploits a unique repertoire of type IV secretion system components for pilus assembly at the bacteria-host cell interface. PLoS Pathog (2011) 1.67
c-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in Western and East Asian Helicobacter pylori strains. J Clin Invest (2012) 1.53
A comprehensive sequence and disease correlation analyses for the C-terminal region of CagA protein of Helicobacter pylori. PLoS One (2009) 1.34
Polymorphism in the CagA EPIYA motif impacts development of gastric cancer. J Clin Microbiol (2009) 1.27
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A Tale of Two Toxins: Helicobacter Pylori CagA and VacA Modulate Host Pathways that Impact Disease. Front Microbiol (2010) 1.00
Helicobacter pylori infection increases the risk of colorectal adenomas: cross-sectional study and meta-analysis. Dig Dis Sci (2012) 0.99
Helicobacter pylori CagA protein polymorphisms and their lack of association with pathogenesis. World J Gastroenterol (2010) 0.99
Helicobacter pylori outer membrane protein HopQ identified as a novel T4SS-associated virulence factor. Cell Microbiol (2013) 0.90
J-Western forms of Helicobacter pylori cagA constitute a distinct phylogenetic group with a widespread geographic distribution. J Bacteriol (2012) 0.90
Polymorphism in the Helicobacter pylori CagA and VacA toxins and disease. Gut Microbes (2013) 0.89
Potentiation of Helicobacter pylori CagA protein virulence through homodimerization. J Biol Chem (2011) 0.88
A specific A/T polymorphism in Western tyrosine phosphorylation B-motifs regulates Helicobacter pylori CagA epithelial cell interactions. PLoS Pathog (2015) 0.88
Helicobacter pylori and gastric cancer in the Middle East: a new enigma? World J Gastroenterol (2010) 0.87
The Helicobacter pylori cag Pathogenicity Island. Methods Mol Biol (2012) 0.86
Complex cellular responses of Helicobacter pylori-colonized gastric adenocarcinoma cells. Infect Immun (2011) 0.85
Helicobacter pylori with stronger intensity of CagA phosphorylation lead to an increased risk of gastric intestinal metaplasia and cancer. BMC Microbiol (2011) 0.84
Worldwide Population Structure, Long-Term Demography, and Local Adaptation of Helicobacter pylori. Genetics (2015) 0.82
Role of Helicobacter pylori CagA molecular variations in induction of host phenotypes with carcinogenic potential. J Infect Dis (2009) 0.80
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Higher frequency of cagA EPIYA-C phosphorylation sites in H. pylori strains from first-degree relatives of gastric cancer patients. BMC Gastroenterol (2012) 0.77
Helicobacter pylori HP0876 is dispensable for heme-iron acquisition but attenuates bacterial adherence to gastric epithelial cells. Curr Microbiol (2012) 0.76
Pathogenetic role of the tyrosine-phosphorylated CagA EPIYA sequence of Helicobacter pylori in histological gastritis in Japanese patients. J Gastroenterol (2009) 0.76
CagA EPIYA polymorphisms in Colombian Helicobacter pylori strains and their influence on disease-associated cellular responses. World J Gastrointest Oncol (2013) 0.76
Helicobacter pylori CagA induced interleukin-8 secretion in gastric epithelial cells. Gastroenterol Hepatol Bed Bench (2016) 0.75
Helicobacter pylori genetic diversity and gastro-duodenal diseases in Malaysia. Sci Rep (2014) 0.75
Computational approaches for evaluating the effect of sequence variations and the intrinsically disordered C-terminal region of the Helicobacter pylori CagA protein on the interaction with tyrosine kinase Src. J Mol Model (2014) 0.75
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A new Helicobacter pylori vacuolating cytotoxin determinant, the intermediate region, is associated with gastric cancer. Gastroenterology (2007) 3.54
Multilocus sequence typing as a replacement for serotyping in Salmonella enterica. PLoS Pathog (2012) 3.37
Host-bacterial interactions in Helicobacter pylori infection. Gastroenterology (2008) 3.25
Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor-immune microenvironment. Cell Host Microbe (2013) 3.21
Clinical relevance of Helicobacter pylori cagA and vacA gene polymorphisms. Gastroenterology (2008) 2.63
Determinants and consequences of different levels of CagA phosphorylation for clinical isolates of Helicobacter pylori. Gastroenterology (2004) 2.40
IBD-what role do Proteobacteria play? Nat Rev Gastroenterol Hepatol (2012) 2.03
A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors. Gastroenterology (2006) 1.98
Inflammation and Cancer II. Role of chronic inflammation and cytokine gene polymorphisms in the pathogenesis of gastrointestinal malignancy. Am J Physiol Gastrointest Liver Physiol (2004) 1.96
Helicobacter pylori dupA is polymorphic, and its active form induces proinflammatory cytokine secretion by mononuclear cells. J Infect Dis (2010) 1.89
Interleukin 1beta polymorphisms increase risk of hypochlorhydria and atrophic gastritis and reduce risk of duodenal ulcer recurrence in Japan. Gastroenterology (2002) 1.85
Differences in virulence markers between Helicobacter pylori strains from Iraq and those from Iran: potential importance of regional differences in H. pylori-associated disease. J Clin Microbiol (2008) 1.84
Sporadic colorectal cancer--role of the commensal microbiota. FEMS Microbiol Lett (2005) 1.82
Cancer and inflammation: promise for biologic therapy. J Immunother (2010) 1.72
Helicobacter pylori binds von Willebrand factor and interacts with GPIb to induce platelet aggregation. Gastroenterology (2003) 1.69
Mannose-binding lectin-2 genetic variation and stomach cancer risk. Int J Cancer (2006) 1.64
The inflammatory microenvironment in colorectal neoplasia. PLoS One (2011) 1.62
Detection of Campylobacter concisus and other Campylobacter species in colonic biopsies from adults with ulcerative colitis. PLoS One (2011) 1.58
Microbiota of de-novo pediatric IBD: increased Faecalibacterium prausnitzii and reduced bacterial diversity in Crohn's but not in ulcerative colitis. Am J Gastroenterol (2012) 1.54
Gastric cancer. Br Med Bull (2008) 1.53
Determinants of non-toxicity in the gastric pathogen Helicobacter pylori. J Biol Chem (2003) 1.51
Functional association between the Helicobacter pylori virulence factors VacA and CagA. J Med Microbiol (2008) 1.44
Polymorphisms in inflammatory response genes and their association with gastric cancer: A HuGE systematic review and meta-analyses. Am J Epidemiol (2010) 1.35
The inflammatory and immune response to Helicobacter pylori infection. Best Pract Res Clin Gastroenterol (2007) 1.35
Helicobacter Pylori associated global gastric cancer burden. Front Biosci (Landmark Ed) (2009) 1.33
Nucleotide-binding oligomerization domain-1 and epidermal growth factor receptor: critical regulators of beta-defensins during Helicobacter pylori infection. J Biol Chem (2006) 1.30
Simple method for determination of the number of Helicobacter pylori CagA variable-region EPIYA tyrosine phosphorylation motifs by PCR. J Clin Microbiol (2005) 1.28
The role of infection in the aetiology of inflammatory bowel disease. J Gastroenterol (2010) 1.26
Increase in NF-kappaB binding affinity of the variant C allele of the toll-like receptor 9 -1237T/C polymorphism is associated with Helicobacter pylori-induced gastric disease. Infect Immun (2009) 1.19
The presence of dupA in Helicobacter pylori is not significantly associated with duodenal ulceration in Belgium, South Africa, China, or North America. Clin Infect Dis (2007) 1.19
Genetic variation in the prostate stem cell antigen gene and upper gastrointestinal cancer in white individuals. Gastroenterology (2010) 1.18
Genetic variation in C20orf54, PLCE1 and MUC1 and the risk of upper gastrointestinal cancers in Caucasian populations. Eur J Cancer Prev (2012) 1.17
Helicobacter pylori stimulates dendritic cells to induce interleukin-17 expression from CD4+ T lymphocytes. Infect Immun (2009) 1.15
Genetic aspects of inflammation and cancer. Biochem J (2008) 1.15
Genetic analysis of Helicobacter pylori strain populations colonizing the stomach at different times postinfection. J Bacteriol (2007) 1.09
Could Helicobacter organisms cause inflammatory bowel disease? FEMS Immunol Med Microbiol (2010) 1.09
CD14-159C/T and TLR9-1237T/C polymorphisms are not associated with gastric cancer risk in Caucasian populations. Eur J Cancer Prev (2009) 1.07
Helicobacter pylori infection and gastric cancer. Best Pract Res Clin Gastroenterol (2007) 1.06
The role of cytokine gene polymorphisms in colorectal cancer and their interaction with aspirin use in the northeast of Scotland. Cancer Epidemiol Biomarkers Prev (2005) 1.06
Helicobacter pylori induces gastric epithelial cell invasion in a c-Met and type IV secretion system-dependent manner. J Biol Chem (2006) 1.05
Toxigenic Helicobacter pylori infection precedes gastric hypochlorhydria in cancer relatives, and H. pylori virulence evolves in these families. Clin Cancer Res (2008) 1.05
The microaerophilic microbiota of de-novo paediatric inflammatory bowel disease: the BISCUIT study. PLoS One (2013) 1.03
Helicobacter pylori infection, host genetics and gastric cancer. J Dig Dis (2009) 1.03
Heterogeneity in the activity of Mexican Helicobacter pylori strains in gastric epithelial cells and its association with diversity in the cagA gene. Infect Immun (2007) 0.99
A comprehensive evaluation of colonic mucosal isolates of Sutterella wadsworthensis from inflammatory bowel disease. PLoS One (2011) 0.96
Current status of Barrett's esophagus research in Asia. J Gastroenterol Hepatol (2011) 0.96
Evolution of the Helicobacter pylori vacuolating cytotoxin in a human stomach. J Bacteriol (2004) 0.94
cagA and vacA genotype of Helicobacter pylori associated with gastric diseases in Xi'an area. World J Gastroenterol (2003) 0.92
Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a Polish population. Jpn J Clin Oncol (2008) 0.92
The matrix metalloproteinase/tissue inhibitor of matrix metalloproteinase profile in colorectal polyp cancers. Histopathology (2009) 0.92
Polymorphism of interleukin-1beta affects the eradication rates of Helicobacter pylori by triple therapy. Clin Gastroenterol Hepatol (2004) 0.90
Increased expression of the urokinase plasminogen activator system by Helicobacter pylori in gastric epithelial cells. Am J Physiol Gastrointest Liver Physiol (2008) 0.89
Helicobacter pylori: host genetics and disease outcomes. Expert Rev Gastroenterol Hepatol (2008) 0.89
Mastic gum has no effect on Helicobacter pylori load in vivo. J Antimicrob Chemother (2003) 0.89
Helicobacter pylori supernatants cause epithelial cytoskeletal disruption that is bacterial strain and epithelial cell line dependent but not toxin VacA dependent. Infect Immun (2003) 0.88
Tyrosine phosphorylation of CagA from Chinese Helicobacter pylori isolates in AGS gastric epithelial cells. J Clin Microbiol (2005) 0.87
A novel method for genotyping the Helicobacter pylori vacA intermediate region directly in gastric biopsy specimens. J Clin Microbiol (2012) 0.87
In Helicobacter pylori, LuxS is a key enzyme in cysteine provision through a reverse transsulfuration pathway. J Bacteriol (2010) 0.87
The role of interleukin-1beta and other potential genetic markers as indicators of gastric cancer risk. Can J Gastroenterol (2003) 0.87
Images of colonic real-time tissue sonoelastography correlate with those of colonoscopy and may predict response to therapy in patients with ulcerative colitis. BMC Gastroenterol (2011) 0.86
Genetics of inflammation in the gastrointestinal tract and how it can cause cancer. Recent Results Cancer Res (2011) 0.86
Role of host genetics in fibrosis. Fibrogenesis Tissue Repair (2009) 0.86
The highly repetitive region of the Helicobacter pylori CagY protein comprises tandem arrays of an alpha-helical repeat module. J Mol Biol (2008) 0.86
The mesenchyme in malignancy: a partner in the initiation, progression and dissemination of cancer. Pharmacol Ther (2012) 0.86
In Helicobacter pylori auto-inducer-2, but not LuxS/MccAB catalysed reverse transsulphuration, regulates motility through modulation of flagellar gene transcription. BMC Microbiol (2010) 0.85
Lack of association between the rs2294008 polymorphism in the prostate stem cell antigen gene and colorectal neoplasia: a case-control and immunohistochemical study. BMC Res Notes (2012) 0.83
Helicobacter pylori-induced inhibition of vascular endothelial cell functions: a role for VacA-dependent nitric oxide reduction. Am J Physiol Heart Circ Physiol (2008) 0.83
The effect of the human gut-signalling hormone, norepinephrine, on the growth of the gastric pathogen Helicobacter pylori. Helicobacter (2009) 0.82
Paired cysteine residues are required for high levels of the Helicobacter pylori autotransporter VacA. Microbiology (2006) 0.82
Possible association between a genetic polymorphism at 8q24 and risk of upper gastrointestinal cancer. Eur J Cancer Prev (2011) 0.82
A study of age-specific Helicobacter pylori seropositivity rates in Iraq. Helicobacter (2008) 0.81
A study of Helicobacter pylori-associated gastritis patterns in Iraq and their association with strain virulence. Saudi J Gastroenterol (2009) 0.81
Cytokine gene polymorphisms, cytokine levels and the risk of colorectal neoplasia in a screened population of Northeast Scotland. Eur J Cancer Prev (2015) 0.81
Genetic aspects of inflammation. Curr Opin Pharmacol (2009) 0.78
The clinical utility and diagnostic yield of routine gastric biopsies in the investigation of iron deficiency anemia: a case-control study. Am J Gastroenterol (2008) 0.78
The effect of different strains of Helicobacter pylori on platelet aggregation. Can J Gastroenterol (2007) 0.77
All subtypes of the cytotoxin VacA adsorb to the surface of Helicobacter pylori post-secretion. J Med Microbiol (2005) 0.76
Brefeldin A enhances Helicobacter pylori vacuolating cytotoxin-induced vacuolation of epithelial cells. FEMS Microbiol Lett (2004) 0.76
Helicobacter pylori susceptibility in the GWAS era. JAMA (2013) 0.76
MicroRNAs in gastrointestinal malignancy: a tool in cancer prevention? Eur J Cancer Prev (2014) 0.76
Genetics of Barrett's: the bigger, the better. Am J Gastroenterol (2012) 0.75
Revision of the Atlanta classification of acute pancreatitis: the editorial perspective. Gut (2013) 0.75
Esophageal cancers and Helicobacter pylori: do host genes matter? Gastroenterology (2010) 0.75
Not All Mice Are the Same: Standardization of Animal Research Data Presentation. Cell Mol Gastroenterol Hepatol (2016) 0.75
How accurate are fecal tests for determination of cure after Helicobacter pylori eradication therapy? Nat Clin Pract Gastroenterol Hepatol (2007) 0.75
Programmed chemotherapy for patients with metastatic unresectable gastric cancer. PLoS One (2012) 0.75
A multi-journal partnership to highlight joint first-authors of manuscripts. Hepatology (2015) 0.75
A multi-journal partnership to highlight joint first-authors of manuscripts. Gastrointest Endosc (2015) 0.75
Human gastrin: a true growth factor for Helicobacter pylori? Helicobacter (2009) 0.75
A multi-journal partnership to highlight joint first-authors of manuscripts. Gastroenterology (2015) 0.75
GP management of dyspepsia. Practitioner (2006) 0.75