Published in Pharmacol Biochem Behav on February 22, 2007
Realistic expectations of prepulse inhibition in translational models for schizophrenia research. Psychopharmacology (Berl) (2008) 2.64
PPI deficit induced by amphetamine is attenuated by the histamine H1 antagonist pyrilamine, but is exacerbated by the serotonin 5-HT2 antagonist ketanserin. Psychopharmacology (Berl) (2010) 0.85
Involvement of histamine receptors in the atypical antipsychotic profile of clozapine: a reassessment in vitro and in vivo. Psychopharmacology (Berl) (2011) 0.80
The α₂-adrenergic antagonist idazoxan counteracts prepulse inhibition deficits caused by amphetamine or dizocilpine in rats. Psychopharmacology (Berl) (2011) 0.78
Meclizine enhancement of sensorimotor gating in healthy male subjects with high startle responses and low prepulse inhibition. Neuropsychopharmacology (2013) 0.75
Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies. Psychopharmacology (Berl) (2001) 5.67
Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review. Psychopharmacology (Berl) (2001) 4.52
Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization. Psychopharmacology (Berl) (2005) 3.92
The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia. Schizophr Bull (1999) 2.10
The effect of clozapine on cognition and psychiatric symptoms in patients with schizophrenia. Br J Psychiatry (1993) 1.75
Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological characterization and broad preclinical efficacy in cognition and schizophrenia of a potent and selective histamine H3 receptor antagonist. J Pharmacol Exp Ther (2004) 1.33
Effects of phencyclidine and phencyclidine biologs on sensorimotor gating in the rat. Neuropsychopharmacology (1989) 1.26
Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response. J Pharmacol Exp Ther (1994) 1.23
General pharmacology of clozapine. Br J Psychiatry Suppl (1992) 1.07
Antipsychotic effects on prepulse inhibition in normal 'low gating' humans and rats. Neuropsychopharmacology (2006) 1.04
Prepulse inhibition of acoustic startle, a measure of sensorimotor gating: effects of antipsychotics and other agents in rats. Pharmacol Biochem Behav (1995) 0.99
New findings in pharmacological effects induced by antihistamines: from PET studies to knock-out mice. Clin Exp Allergy (1999) 0.96
Nicotine interactions with haloperidol, clozapine and risperidone and working memory function in rats. Neuropsychopharmacology (2002) 0.95
The cognitive efficacy of atypical antipsychotics in schizophrenia. J Clin Psychopharmacol (1998) 0.94
Effects of cannabinoid receptor ligands on psychosis-relevant behavior models in the rat. Psychopharmacology (Berl) (2002) 0.93
Differential effect of antipsychotics on place navigation of rats in the Morris water maze. A comparative study between novel and reference antipsychotics. Psychopharmacology (Berl) (1996) 0.93
Effects of a typical and an atypical antipsychotic on the disruption of prepulse inhibition caused by corticotropin-releasing factor and by rat strain. Behav Neurosci (2005) 0.91
Failure of haloperidol to block the effects of phencyclidine and dizocilpine on prepulse inhibition of startle. Biol Psychiatry (1991) 0.90
A putative animal model of the "prodromal" state of schizophrenia. Biol Psychiatry (2005) 0.89
Virally mediated increased neurotensin 1 receptor in the nucleus accumbens decreases behavioral effects of mesolimbic system activation. J Neurosci (2005) 0.89
Effects of histamine H3 receptor antagonists in two models of spatial learning. Behav Brain Res (2004) 0.88
Ventral hippocampal alpha7 and alpha4beta2 nicotinic receptor blockade and clozapine effects on memory in female rats. Psychopharmacology (Berl) (2006) 0.88
The effect of zotepine, risperidone, clozapine and olanzapine on MK-801-disrupted sensorimotor gating. Pharmacol Biochem Behav (2005) 0.86
The effects of clozapine on symptom reduction, neurocognitive function, and clinical management in treatment-refractory state hospital schizophrenic inpatients. Neuropsychopharmacology (1996) 0.85
Chronic nicotine interactions with clozapine and risperidone and attentional function in rats. Prog Neuropsychopharmacol Biol Psychiatry (2005) 0.85
Enhancement of prepulse inhibition of startle in mice by the H3 receptor antagonists thioperamide and ciproxifan. Behav Brain Res (2004) 0.85
Activation of D1, but not D2 receptors potentiates dizocilpine-mediated disruption of prepulse inhibition of the startle. Neuropsychopharmacology (2005) 0.85
The effects of clozapine on cognitive functioning in schizophrenia. J Clin Psychiatry (1999) 0.85
Histaminergic neurons facilitate social memory in rats. Brain Res (1996) 0.85
Effects of clozapine on memory function in the rat neonatal hippocampal lesion model of schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry (2005) 0.84
Effects of histamine and cholinergic systems on memory retention of passive avoidance learning in rats. Eur J Pharmacol (2003) 0.84
Importance of histamine in modulatory processes, locomotion and memory. Behav Brain Res (2001) 0.83
Reversal of clozapine effects on working memory in rats with fimbria-fornix lesions. Neuropsychopharmacology (2005) 0.83
Nicotine and clozapine actions on pre-pulse inhibition deficits caused by N-methyl-D-aspartate (NMDA) glutamatergic receptor blockade. Prog Neuropsychopharmacol Biol Psychiatry (2005) 0.82
Clozapine enhances disruption of prepulse inhibition after sub-chronic dizocilpine- or phencyclidine-treatment in Wistar rats. Pharmacol Biochem Behav (2004) 0.81
Effect of H1-antagonists on spatial memory deficit evaluated by 8-arm radial maze in rats. Acta Pharmacol Sin (2001) 0.81
Blockage of histamine H1 receptor attenuates social isolation-induced disruption of prepulse inhibition: a study in H1 receptor gene knockout mice. Psychopharmacology (Berl) (2005) 0.80
Effects of vasopressin on histamine H(1) receptor antagonist-induced spatial memory deficits in rats. Eur J Pharmacol (2001) 0.80
Cholinergic and glutamatergic activation reverses working memory failure by hippocampal histamine H1 receptor blockade in rats. Life Sci (2000) 0.79
Histamine ameliorates spatial memory deficits induced by MK-801 infusion into ventral hippocampus as evaluated by radial maze task in rats. Acta Pharmacol Sin (2005) 0.79
Influence of certain H1-blockers on the step-through active avoidance response in rats. Psychopharmacology (Berl) (1990) 0.78
Therapeutic advantages of third generation antihistamines. Expert Opin Investig Drugs (1998) 0.78
Effects of the NMDA antagonist MK-801 on radial maze performance in histidine-deficient rats. Life Sci (2002) 0.77
Interaction of astemizole, an H1 receptor antagonist, with conventional antiepileptic drugs in mice. Pharmacol Biochem Behav (2003) 0.77
Clozapine treatment reverses dizocilpine-induced deficits of pre-pulse inhibition of tactile startle response. Pharmacol Biochem Behav (2007) 0.77
Effects of NMDA antagonist MK-801 on radial maze performance in Zucker rats. Brain Res (2002) 0.76
Sensorimotor and cognitive performance of schizophrenic inpatients treated with haloperidol, flupenthixol, or clozapine. Pharmacopsychiatry (1988) 0.76
Comparative study of various H1-blockers on neuropharmacological and behavioral effects including 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidazole difumarate (KB-2413), a new antiallergic agent. Arch Int Pharmacodyn Ther (1986) 0.76
Guidelines on nicotine dose selection for in vivo research. Psychopharmacology (Berl) (2006) 3.68
Are adolescents more vulnerable to drug addiction than adults? Evidence from animal models. Psychopharmacology (Berl) (2009) 2.06
The toxicology of climate change: environmental contaminants in a warming world. Environ Int (2009) 1.82
Developmental exposure of rats to chlorpyrifos leads to behavioral alterations in adulthood, involving serotonergic mechanisms and resembling animal models of depression. Environ Health Perspect (2005) 1.79
Buspirone, chlordiazepoxide and diazepam effects in a zebrafish model of anxiety. Pharmacol Biochem Behav (2009) 1.74
Comparative developmental neurotoxicity of organophosphate insecticides: effects on brain development are separable from systemic toxicity. Environ Health Perspect (2006) 1.69
Consumption of a high-fat diet in adulthood ameliorates the effects of neonatal parathion exposure on acetylcholine systems in rat brain regions. Environ Health Perspect (2009) 1.56
Zebrafish provide a sensitive model of persisting neurobehavioral effects of developmental chlorpyrifos exposure: comparison with nicotine and pilocarpine effects and relationship to dopamine deficits. Neurotoxicol Teratol (2009) 1.44
Organophosphate insecticides target the serotonergic system in developing rat brain regions: disparate effects of diazinon and parathion at doses spanning the threshold for cholinesterase inhibition. Environ Health Perspect (2006) 1.42
Tough and Hydrophilic Photonic Crystals Obtained from Direct UV Irradiation. Macromol Rapid Commun (2010) 1.38
Persistent cognitive alterations in rats after early postnatal exposure to low doses of the organophosphate pesticide, diazinon. Neurotoxicol Teratol (2007) 1.36
Developmental diazinon neurotoxicity in rats: later effects on emotional response. Brain Res Bull (2007) 1.32
Behavioral alterations in adolescent and adult rats caused by a brief subtoxic exposure to chlorpyrifos during neurulation. Neurotoxicol Teratol (2004) 1.27
Persistent behavioral alterations in rats neonatally exposed to low doses of the organophosphate pesticide, parathion. Brain Res Bull (2008) 1.26
Mode of action: disruption of brain cell replication, second messenger, and neurotransmitter systems during development leading to cognitive dysfunction--developmental neurotoxicity of nicotine. Crit Rev Toxicol (2006) 1.25
Adolescent vulnerabilities to chronic alcohol or nicotine exposure: findings from rodent models. Alcohol Clin Exp Res (2005) 1.24
Neonatal exposure to low doses of diazinon: long-term effects on neural cell development and acetylcholine systems. Environ Health Perspect (2008) 1.22
Effects of sazetidine-A, a selective alpha4beta2 nicotinic acetylcholine receptor desensitizing agent on alcohol and nicotine self-administration in selectively bred alcohol-preferring (P) rats. Psychopharmacology (Berl) (2010) 1.20
The role of alpha7 and alpha4beta2 nicotinic receptors in the nicotine-induced anxiolytic effect in zebrafish. Physiol Behav (2008) 1.20
Nicotine effects on learning in zebrafish: the role of dopaminergic systems. Psychopharmacology (Berl) (2008) 1.16
Metallothionein in the central nervous system: Roles in protection, regeneration and cognition. Neurotoxicology (2008) 1.15
Evaluation of the association between maternal smoking, childhood obesity, and metabolic disorders: a national toxicology program workshop review. Environ Health Perspect (2012) 1.13
Transdermal nicotine attenuates depression symptoms in nonsmokers: a double-blind, placebo-controlled trial. Psychopharmacology (Berl) (2006) 1.10
Exposure of neonatal rats to parathion elicits sex-selective reprogramming of metabolism and alters the response to a high-fat diet in adulthood. Environ Health Perspect (2008) 1.09
Developmental neurotoxicity of low dose diazinon exposure of neonatal rats: effects on serotonin systems in adolescence and adulthood. Brain Res Bull (2007) 1.04
Differential acetylcholinesterase inhibition of chlorpyrifos, diazinon and parathion in larval zebrafish. Neurotoxicol Teratol (2011) 1.04
Sazetidine-A, a selective α4β2 nicotinic acetylcholine receptor ligand: effects on dizocilpine and scopolamine-induced attentional impairments in female Sprague-Dawley rats. Psychopharmacology (Berl) (2011) 1.02
Role of individual and developmental differences in voluntary cocaine intake in rats. Psychopharmacology (Berl) (2011) 1.00
Assessing the effects of chronic sazetidine-A delivery on nicotine self-administration in both male and female rats. Psychopharmacology (Berl) (2012) 1.00
Exposure of neonatal rats to parathion elicits sex-selective impairment of acetylcholine systems in brain regions during adolescence and adulthood. Environ Health Perspect (2008) 1.00
Developmental neurotoxicity of parathion: progressive effects on serotonergic systems in adolescence and adulthood. Neurotoxicol Teratol (2008) 0.99
Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain. J Pharmacol Exp Ther (2012) 0.99
Zebrafish model systems for developmental neurobehavioral toxicology. Birth Defects Res C Embryo Today (2013) 0.98
Critical duration of exposure for developmental chlorpyrifos-induced neurobehavioral toxicity. Neurotoxicol Teratol (2011) 0.97
Effects of nicotine and mecamylamine on choice accuracy in an operant visual signal detection task in female rats. Psychopharmacology (Berl) (2002) 0.97
Nicotine-antipsychotic drug interactions and attentional performance in female rats. Eur J Pharmacol (2004) 0.96
Neonatal exposure to parathion alters lipid metabolism in adulthood: Interactions with dietary fat intake and implications for neurodevelopmental deficits. Brain Res Bull (2010) 0.96
Chronic inhibition of alpha4beta2 nicotinic receptors in the ventral hippocampus of rats: impacts on memory and nicotine response. Psychopharmacology (Berl) (2001) 0.95
Nicotine interactions with haloperidol, clozapine and risperidone and working memory function in rats. Neuropsychopharmacology (2002) 0.95
Nicotine and clozapine effects on attentional performance impaired by the NMDA antagonist dizocilpine in female rats. Int J Neuropsychopharmacol (2007) 0.94
Dorsal hippocampal alpha7 and alpha4beta2 nicotinic receptors and memory. Brain Res (2006) 0.94
Effects of caffeine on alcohol consumption and nicotine self-administration in rats. Alcohol Clin Exp Res (2013) 0.94
Chronic transdermal nicotine patch treatment effects on cognitive performance in age-associated memory impairment. Psychopharmacology (Berl) (2003) 0.94
Adolescent and adult rats respond differently to nicotine and alcohol: motor activity and body temperature. Int J Dev Neurosci (2004) 0.92
Effect of R3487/MEM3454, a novel nicotinic alpha7 receptor partial agonist and 5-HT3 antagonist on sustained attention in rats. Prog Neuropsychopharmacol Biol Psychiatry (2008) 0.92
The novel, selective, brain-penetrant neuropeptide Y Y2 receptor antagonist, JNJ-31020028, tested in animal models of alcohol consumption, relapse, and anxiety. Alcohol (2010) 0.92
Metallothionein expression and neurocognitive function in mice. Physiol Behav (2006) 0.92
Undertaking positive control studies as part of developmental neurotoxicity testing: a report from the ILSI Research Foundation/Risk Science Institute expert working group on neurodevelopmental endpoints. Neurotoxicol Teratol (2007) 0.91
Mercury-induced cognitive impairment in metallothionein-1/2 null mice. Neurotoxicol Teratol (2007) 0.91
Long-term effects of chronic intermittent ethanol exposure in adolescent and adult rats: radial-arm maze performance and operant food reinforced responding. PLoS One (2013) 0.90
Nicotinic-glutamatergic interactions and attentional performance on an operant visual signal detection task in female rats. Eur J Pharmacol (2003) 0.89
Nicotinic mechanisms of memory: effects of acute local DHbetaE and MLA infusions in the basolateral amygdala. Brain Res Cogn Brain Res (2003) 0.89
Chemistry and pharmacological studies of 3-alkoxy-2,5-disubstituted-pyridinyl compounds as novel selective α4β2 nicotinic acetylcholine receptor ligands that reduce alcohol intake in rats. J Med Chem (2013) 0.88
Branched-chain amino acids alter neurobehavioral function in rats. Am J Physiol Endocrinol Metab (2012) 0.88
Gestational dexamethasone treatment elicits sex-dependent alterations in locomotor activity, reward-based memory and hippocampal cholinergic function in adolescent and adult rats. Neuropsychopharmacology (2005) 0.88
Ventral hippocampal alpha7 and alpha4beta2 nicotinic receptor blockade and clozapine effects on memory in female rats. Psychopharmacology (Berl) (2006) 0.88
Heterogeneity of toxicant response: sources of human variability. Toxicol Sci (2003) 0.87
Developmental and behavioral effects of embryonic exposure to the polybrominated diphenylether mixture DE-71 in the killifish (Fundulus heteroclitus). Chemosphere (2005) 0.87
Attenuation of pharmacologically-induced attentional impairment by methylphenidate in rats. Pharmacol Biochem Behav (2008) 0.87
JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats. Psychopharmacology (Berl) (2010) 0.87
Nicotine-alcohol interactions and attentional performance on an operant visual signal detection task in female rats. Pharmacol Biochem Behav (2003) 0.86
Persistent high alcohol consumption in alcohol-preferring (P) rats results from a lack of normal aversion to alcohol. Alcohol Alcohol (2010) 0.86
Carisbamate, a novel antiepileptic candidate compound, attenuates alcohol intake in alcohol-preferring rats. Alcohol Clin Exp Res (2009) 0.86
Role of insular cortex D₁ and D₂ dopamine receptors in nicotine self-administration in rats. Behav Brain Res (2013) 0.85
Chronic nicotine interactions with clozapine and risperidone and attentional function in rats. Prog Neuropsychopharmacol Biol Psychiatry (2005) 0.85
PPI deficit induced by amphetamine is attenuated by the histamine H1 antagonist pyrilamine, but is exacerbated by the serotonin 5-HT2 antagonist ketanserin. Psychopharmacology (Berl) (2010) 0.85
Design and synthesis of potent and multifunctional aldose reductase inhibitors based on quinoxalinones. J Med Chem (2015) 0.85
Design, synthesis and discovery of picomolar selective α4β2 nicotinic acetylcholine receptor ligands. J Med Chem (2013) 0.84
Nicotinic antagonist effects in the mediodorsal thalamic nucleus: regional heterogeneity of nicotinic receptor involvement in cognitive function. Biochem Pharmacol (2009) 0.84
Nicotinic-serotonergic drug interactions and attentional performance in rats. Psychopharmacology (Berl) (2005) 0.83
Effects of AZD3480, a neuronal nicotinic acetylcholine receptor agonist, and donepezil on dizocilpine-induced attentional impairment in rats. Psychopharmacology (Berl) (2012) 0.83
IV nicotine self-administration in rats using the consummatory operant licking response. Physiol Behav (2010) 0.83
Effects of sazetidine-A, a selective α4β2* nicotinic receptor desensitizing agent, on body temperature regulation in mice and rats. Eur J Pharmacol (2012) 0.83
Reversal of clozapine effects on working memory in rats with fimbria-fornix lesions. Neuropsychopharmacology (2005) 0.83
NMDA systems in the amygdala and piriform cortex and nicotinic effects on memory function. Brain Res Cogn Brain Res (2003) 0.82
Hippocampal infusions of apolipoprotein E peptides induce long-lasting cognitive impairment. Brain Res Bull (2009) 0.82
Phase modulation and structural effects in a D-shaped all-solid photonic crystal fiber surface plasmon resonance sensor. Opt Express (2014) 0.82
Flexible graphene-based electroluminescent devices. ACS Nano (2011) 0.82
Gene-environment interactions: neurodegeneration in non-mammals and mammals. Neurotoxicology (2010) 0.81
Hippocampal infusions of MARCKS peptides impair memory of rats on the radial-arm maze. Brain Res (2009) 0.81
Effects of atypical anxiolytic N-phenyl-2-[1-[3-(2-pyridinylethynyl)benzoyl]-4-piperidine]acetamide (JNJ-5234801) on alcohol intake in alcohol-preferring P rats. Alcohol Clin Exp Res (2007) 0.81
Neonatal parathion exposure and interactions with a high-fat diet in adulthood: Adenylyl cyclase-mediated cell signaling in heart, liver and cerebellum. Brain Res Bull (2010) 0.81
Chronic nicotine and dizocilpine effects on nicotinic and NMDA glutamatergic receptor regulation: interactions with clozapine actions and attentional performance in rats. Prog Neuropsychopharmacol Biol Psychiatry (2008) 0.81
Reliabilities and intercorrelations of reported and objective measures of smoking in patients with schizophrenia. Schizophr Res (2003) 0.81
The use of zebrafish (Danio rerio) as a model system in neurobehavioral toxicology. Neurotoxicol Teratol (2004) 0.81
Transcriptional profiling of whole blood and serum protein analysis of mice exposed to the neurotoxin Pacific Ciguatoxin-1. Neurotoxicology (2007) 0.81
Effects of ethanol, Δ(9)-tetrahydrocannabinol, or their combination on object recognition memory and object preference in adolescent and adult male rats. Neurosci Lett (2012) 0.81
Repeat exposure to ciguatoxin leads to enhanced and sustained thermoregulatory, pain threshold and motor activity responses in mice: relationship to blood ciguatoxin concentrations. Toxicology (2007) 0.81
Effects of chronic sazetidine-A, a selective α4β2 neuronal nicotinic acetylcholine receptors desensitizing agent on pharmacologically-induced impaired attention in rats. Psychopharmacology (Berl) (2012) 0.81
Neonatal parathion exposure disrupts serotonin and dopamine synaptic function in rat brain regions: modulation by a high-fat diet in adulthood. Neurotoxicol Teratol (2009) 0.79
Liver genomic responses to ciguatoxin: evidence for activation of phase I and phase II detoxification pathways following an acute hypothermic response in mice. Toxicol Sci (2008) 0.79
The α₂-adrenergic antagonist idazoxan counteracts prepulse inhibition deficits caused by amphetamine or dizocilpine in rats. Psychopharmacology (Berl) (2011) 0.78
Novel medication targets for the treatment of alcoholism: preclinical studies. Recent Pat CNS Drug Discov (2012) 0.78
Copper-catalyzed asymmetric synthesis and comparative aldose reductase inhibition activity of (+)/(-)-1,2-benzothiazine-1,1-dioxide acetic acid derivatives. J Org Chem (2014) 0.78
Research facilities. China supersizes its science. Science (2007) 0.78
Differential effects of the antidepressant mirtazapine on amphetamine- and dizocilpine-induced PPI deficits. Pharmacol Biochem Behav (2012) 0.77
Nicotine-alcohol interactions and cognitive function in rats. Pharmacol Biochem Behav (2002) 0.77
Interaction of nicotinic and histamine H(3) systems in the radial-arm maze repeated acquisition task. Eur J Pharmacol (2007) 0.77
Clozapine treatment reverses dizocilpine-induced deficits of pre-pulse inhibition of tactile startle response. Pharmacol Biochem Behav (2007) 0.77