Published in Ann Hum Genet on March 27, 2007
Recovering unused information in genome-wide association studies: the benefit of analyzing SNPs out of Hardy-Weinberg equilibrium. Eur J Hum Genet (2009) 1.12
Genomic scan of selective sweeps in thin and fat tail sheep breeds for identifying of candidate regions associated with fat deposition. BMC Genet (2012) 1.07
IL1RN coding variant is associated with lower risk of acute respiratory distress syndrome and increased plasma IL-1 receptor antagonist. Am J Respir Crit Care Med (2013) 1.03
Association of cytokine and Toll-like receptor gene polymorphisms with severe malaria in three regions of Cameroon. PLoS One (2013) 0.91
Signatures of selection in sheep bred for resistance or susceptibility to gastrointestinal nematodes. BMC Genomics (2014) 0.91
Using both cases and controls for testing hardy-weinberg proportions in a genetic association study. Hum Hered (2010) 0.90
Impact of genotyping errors on the type I error rate and the power of haplotype-based association methods. BMC Genet (2009) 0.85
A quality control algorithm for filtering SNPs in genome-wide association studies. Bioinformatics (2010) 0.83
Perturbation analysis: a simple method for filtering SNPs with erroneous genotyping in genome-wide association studies. Ann Hum Genet (2008) 0.81
Lack of association of interferon regulatory factor 1 with severe malaria in affected child-parental trio studies across three African populations. PLoS One (2009) 0.80
Genome-wide association studies--a summary for the clinical gastroenterologist. World J Gastroenterol (2009) 0.78
Association of candidate gene polymorphisms and TGF-beta/IL-10 levels with malaria in three regions of Cameroon: a case-control study. Malar J (2014) 0.78
DNA repair variants, indoor tanning, and risk of melanoma. Pigment Cell Melanoma Res (2013) 0.75
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study. N Engl J Med (2007) 12.24
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet (2010) 9.90
A genotype calling algorithm for the Illumina BeadArray platform. Bioinformatics (2007) 8.03
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet (2011) 7.98
Mapping human genetic diversity in Asia. Science (2009) 7.40
Patterns of linkage disequilibrium in the human genome. Nat Rev Genet (2002) 7.09
Common variants at CD40 and other loci confer risk of rheumatoid arthritis. Nat Genet (2008) 7.07
Quantification of the completeness of follow-up. Lancet (2002) 4.77
Genome-wide association identifies multiple ulcerative colitis susceptibility loci. Nat Genet (2010) 4.65
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nat Genet (2011) 4.50
Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing. Nature (2012) 4.37
Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet (2009) 4.30
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia. Proc Natl Acad Sci U S A (2012) 4.10
Sequence-level population simulations over large genomic regions. Genetics (2007) 4.04
Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. Nat Genet (2011) 4.04
Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice. PLoS Pathog (2012) 3.81
Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk. Nat Genet (2009) 3.52
Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nat Genet (2011) 3.46
Genome-wide significance for dense SNP and resequencing data. Genet Epidemiol (2008) 3.26
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Meta-analysis identifies common variants associated with body mass index in east Asians. Nat Genet (2012) 2.70
Identification of new genetic risk variants for type 2 diabetes. PLoS Genet (2010) 2.62
Genetic structure of the Han Chinese population revealed by genome-wide SNP variation. Am J Hum Genet (2009) 2.33
Testing for population subdivision and association in four case-control studies. Am J Hum Genet (2002) 2.26
Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance. Genome Res (2011) 2.21
Relationship between glycated haemoglobin and microvascular complications: is there a natural cut-off point for the diagnosis of diabetes? Diabetologia (2009) 2.09
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nat Genet (2012) 2.05
FTO variants are associated with obesity in the Chinese and Malay populations in Singapore. Diabetes (2008) 2.05
Allelic heterogeneity of G6PD deficiency in West Africa and severe malaria susceptibility. Eur J Hum Genet (2009) 1.94
Assessing publication bias in genetic association studies: evidence from a recent meta-analysis. Psychiatry Res (2004) 1.92
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. Ann Rheum Dis (2010) 1.90
Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region. Arthritis Rheum (2009) 1.87
Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia. PLoS Genet (2011) 1.81
Comparative analyses of seven algorithms for copy number variant identification from single nucleotide polymorphism arrays. Nucleic Acids Res (2010) 1.77
Personality and smoking status: a meta-analysis. Nicotine Tob Res (2007) 1.76
Singapore Genome Variation Project: a haplotype map of three Southeast Asian populations. Genome Res (2009) 1.73
Immune phenotype predicts risk for posttransplantation squamous cell carcinoma. J Am Soc Nephrol (2010) 1.72
De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome. Nat Genet (2012) 1.70
Distinct phases of blood gene expression pattern through tuberculosis treatment reflect modulation of the humoral immune response. J Infect Dis (2012) 1.69
Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis. PLoS Genet (2008) 1.65
Association of sub-microscopic malaria parasite carriage with transmission intensity in north-eastern Tanzania. Malar J (2011) 1.63
Genome-wide expression profiling identifies type 1 interferon response pathways in active tuberculosis. PLoS One (2012) 1.58
SpolPred: rapid and accurate prediction of Mycobacterium tuberculosis spoligotypes from short genomic sequences. Bioinformatics (2012) 1.56
Collagen-related genes influence the glaucoma risk factor, central corneal thickness. Hum Mol Genet (2010) 1.52
Positive selection of a CD36 nonsense variant in sub-Saharan Africa, but no association with severe malaria phenotypes. Hum Mol Genet (2009) 1.50
Polymorphisms identified through genome-wide association studies and their associations with type 2 diabetes in Chinese, Malays, and Asian-Indians in Singapore. J Clin Endocrinol Metab (2009) 1.46
Genetic affinity and admixture of northern Thai people along their migration route in northern Thailand: evidence from autosomal STR loci. J Hum Genet (2010) 1.45
Genome-wide association studies reveal genetic variants in CTNND2 for high myopia in Singapore Chinese. Ophthalmology (2010) 1.44
In the absence of dietary surveillance, chitosan does not reduce plasma lipids or obesity in hypercholesterolaemic obese Asian subjects. Singapore Med J (2001) 1.43
Genome-wide comparisons of variation in linkage disequilibrium. Genome Res (2009) 1.43
Identification of tuberculosis susceptibility genes with human macrophage gene expression profiles. PLoS Pathog (2008) 1.41
Overlapping cortical malformations and mutations in TUBB2B and TUBA1A. Brain (2013) 1.40
An effective method to purify Plasmodium falciparum DNA directly from clinical blood samples for whole genome high-throughput sequencing. PLoS One (2011) 1.39
Characterization of within-host Plasmodium falciparum diversity using next-generation sequence data. PLoS One (2012) 1.36
Drug-resistant genotypes and multi-clonality in Plasmodium falciparum analysed by direct genome sequencing from peripheral blood of malaria patients. PLoS One (2011) 1.34
Use of purified Clostridium difficile spores to facilitate evaluation of health care disinfection regimens. Appl Environ Microbiol (2010) 1.32
Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area. Hum Mol Genet (2011) 1.29
A genome-wide association study of hepatitis B vaccine response in an Indonesian population reveals multiple independent risk variants in the HLA region. Hum Mol Genet (2011) 1.28
Imputation-based meta-analysis of severe malaria in three African populations. PLoS Genet (2013) 1.25
MET and autism susceptibility: family and case-control studies. Eur J Hum Genet (2008) 1.24
Estimating the number of coding mutations in genotypic- and phenotypic-driven N-ethyl-N-nitrosourea (ENU) screens. Mamm Genome (2006) 1.24
How genetically heterogeneous is Kabuki syndrome?: MLL2 testing in 116 patients, review and analyses of mutation and phenotypic spectrum. Eur J Hum Genet (2011) 1.20
Validating discovered Cis-acting regulatory genetic variants: application of an allele specific expression approach to HapMap populations. PLoS One (2008) 1.20
High-throughput analysis of candidate imprinted genes and allele-specific gene expression in the human term placenta. BMC Genet (2010) 1.18
A whole genome long-range haplotype (WGLRH) test for detecting imprints of positive selection in human populations. Bioinformatics (2006) 1.17
Genetic variants on chromosome 1q41 influence ocular axial length and high myopia. PLoS Genet (2012) 1.17
Tumor necrosis factor and lymphotoxin-alpha polymorphisms and severe malaria in African populations. J Infect Dis (2009) 1.17
Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay. PLoS One (2011) 1.13
Graves' ophthalmopathy in the absence of elevated free thyroxine and triiodothyronine levels: prevalence, natural history, and thyrotropin receptor antibody levels. Thyroid (2000) 1.13
A novel Y-chromosome variant puts an upper limit on the timing of first entry into the Americas. Am J Hum Genet (2003) 1.13
A genome wide association study of pulmonary tuberculosis susceptibility in Indonesians. BMC Med Genet (2012) 1.12
Association of skin barrier genes within the PSORS4 locus is enriched in Singaporean Chinese with early-onset psoriasis. J Invest Dermatol (2008) 1.11
Analysis of association of the TIRAP (MAL) S180L variant and tuberculosis in three populations. Nat Genet (2008) 1.10
Polymorphisms at newly identified lipid-associated loci are associated with blood lipids and cardiovascular disease in an Asian Malay population. J Lipid Res (2008) 1.09
Association between the APOA2 promoter polymorphism and body weight in Mediterranean and Asian populations: replication of a gene-saturated fat interaction. Int J Obes (Lond) (2010) 1.08
Power consequences of linkage disequilibrium variation between populations. Genet Epidemiol (2009) 1.08
Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya. Sci Rep (2013) 1.07
Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4. Diabetologia (2013) 1.07
A 32 kb critical region excluding Y402H in CFH mediates risk for age-related macular degeneration. PLoS One (2011) 1.05
Detecting and characterizing genomic signatures of positive selection in global populations. Am J Hum Genet (2013) 1.04
Neuroticism mediates the association of the serotonin transporter gene with lifetime major depression. Neuropsychobiology (2005) 1.04
Assessing genuine parents-offspring trios for genetic association studies. Hum Hered (2008) 1.03
Pathway-based analysis using reduced gene subsets in genome-wide association studies. BMC Bioinformatics (2011) 1.02
Whole genome-amplified DNA: insights and imputation. Nat Methods (2008) 1.02
Candidate human genetic polymorphisms and severe malaria in a Tanzanian population. PLoS One (2012) 0.99
SgD-CNV, a database for common and rare copy number variants in three Asian populations. Hum Mutat (2011) 0.99
VarB: a variation browsing and analysis tool for variants derived from next-generation sequencing data. Bioinformatics (2012) 0.98
Effective preparation of Plasmodium vivax field isolates for high-throughput whole genome sequencing. PLoS One (2013) 0.98
PlasmoView: a web-based resource to visualise global Plasmodium falciparum genomic variation. J Infect Dis (2013) 0.97