PubRank

Wolfgang Brück

Author PubWeight™ 170.80‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions. Nat Neurosci 2007 6.23
2 Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain 2005 5.29
3 The immunopathology of multiple sclerosis: an overview. Brain Pathol 2007 4.23
4 Inflammatory cortical demyelination in early multiple sclerosis. N Engl J Med 2011 4.02
5 Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system. Immunity 2008 3.67
6 Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway. Brain 2011 3.38
7 Epstein-Barr virus infection is not a characteristic feature of multiple sclerosis brain. Brain 2009 3.04
8 A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis. Nat Med 2011 3.00
9 Relation between humoral pathological changes in multiple sclerosis and response to therapeutic plasma exchange. Lancet 2005 2.68
10 CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system. Brain 2009 2.59
11 Autologous haematopoietic stem cell transplantation fails to stop demyelination and neurodegeneration in multiple sclerosis. Brain 2007 2.46
12 Remyelination is extensive in a subset of multiple sclerosis patients. Brain 2006 2.43
13 Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease. J Neurosci 2011 2.31
14 Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time. Brain 2002 2.27
15 Microglial phenotype: is the commitment reversible? Trends Neurosci 2006 2.18
16 Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis. J Clin Invest 2006 2.17
17 Tissue preconditioning may explain concentric lesions in Baló's type of multiple sclerosis. Brain 2005 2.07
18 Identification of a pathogenic antibody response to native myelin oligodendrocyte glycoprotein in multiple sclerosis. Proc Natl Acad Sci U S A 2006 1.79
19 Neuronal injury in bacterial meningitis: mechanisms and implications for therapy. Trends Neurosci 2002 1.78
20 Mechanisms of acute axonal degeneration in the optic nerve in vivo. Proc Natl Acad Sci U S A 2010 1.70
21 Association between pathological and MRI findings in multiple sclerosis. Lancet Neurol 2012 1.70
22 Distinct lesion morphology at 7-T MRI differentiates neuromyelitis optica from multiple sclerosis. Neurology 2012 1.67
23 Circulating monocytes engraft in the brain, differentiate into microglia and contribute to the pathology following meningitis in mice. Brain 2006 1.63
24 Early MRI changes in a mouse model of multiple sclerosis are predictive of severe inflammatory tissue damage. Brain 2007 1.63
25 Acute effects of intracranial hypertension and ARDS on pulmonary and neuronal damage: a randomized experimental study in pigs. Intensive Care Med 2011 1.57
26 Preferential loss of myelin-associated glycoprotein reflects hypoxia-like white matter damage in stroke and inflammatory brain diseases. J Neuropathol Exp Neurol 2003 1.55
27 Microglia inflict delayed brain injury after subarachnoid hemorrhage. Acta Neuropathol 2015 1.51
28 Widespread demyelination in the cerebellar cortex in multiple sclerosis. Brain Pathol 2007 1.49
29 Ectopic expression of neural autoantigen in mouse liver suppresses experimental autoimmune neuroinflammation by inducing antigen-specific Tregs. J Clin Invest 2008 1.44
30 Iron and neurodegeneration in the multiple sclerosis brain. Ann Neurol 2013 1.43
31 Extensive cortical remyelination in patients with chronic multiple sclerosis. Brain Pathol 2007 1.41
32 IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous system. Brain 2011 1.37
33 A new focal EAE model of cortical demyelination: multiple sclerosis-like lesions with rapid resolution of inflammation and extensive remyelination. Brain 2006 1.35
34 BDNF and gp145trkB in multiple sclerosis brain lesions: neuroprotective interactions between immune and neuronal cells? Brain 2002 1.33
35 Immunological and clinical consequences of treating a patient with natalizumab. Mult Scler 2011 1.33
36 Targeting experimental autoimmune encephalomyelitis lesions to a predetermined axonal tract system allows for refined behavioral testing in an animal model of multiple sclerosis. Am J Pathol 2004 1.31
37 Cortical pathology in multiple sclerosis. Curr Opin Neurol 2008 1.31
38 Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulin. J Neuroimmunol 2011 1.27
39 T cell-dependence of Lassa fever pathogenesis. PLoS Pathog 2010 1.25
40 Primary hypophysitis: clinical-pathological correlations. Eur J Endocrinol 2006 1.25
41 Remodeling of axonal connections contributes to recovery in an animal model of multiple sclerosis. J Exp Med 2004 1.25
42 Inflammation, demyelination, and degeneration - recent insights from MS pathology. Biochim Biophys Acta 2010 1.20
43 Multicontrast MRI of remyelination in the central nervous system. NMR Biomed 2005 1.19
44 A new paraclinical CSF marker for hypoxia-like tissue damage in multiple sclerosis lesions. Brain 2003 1.18
45 Therapeutic decisions in multiple sclerosis: moving beyond efficacy. JAMA Neurol 2013 1.16
46 Laquinimod interferes with migratory capacity of T cells and reduces IL-17 levels, inflammatory demyelination and acute axonal damage in mice with experimental autoimmune encephalomyelitis. J Neuroimmunol 2010 1.15
47 Cell type-specific Nrf2 expression in multiple sclerosis lesions. Acta Neuropathol 2015 1.15
48 Inflammatory changes are tightly associated with neurodegeneration in the brain and spinal cord of the APP/PS1KI mouse model of Alzheimer's disease. Neurobiol Aging 2008 1.12
49 Pathology of immune reconstitution inflammatory syndrome in multiple sclerosis with natalizumab-associated progressive multifocal leukoencephalopathy. Acta Neuropathol 2011 1.12
50 TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis. Nat Med 2012 1.11
51 Negative impact of statins on oligodendrocytes and myelin formation in vitro and in vivo. J Neurosci 2008 1.10
52 Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons. Acta Neuropathol 2013 1.08
53 Toll-like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia. Glia 2012 1.08
54 Specific central nervous system recruitment of HLA-G(+) regulatory T cells in multiple sclerosis. Ann Neurol 2009 1.08
55 Assessment of lesion pathology in a new animal model of MS by multiparametric MRI and DTI. Neuroimage 2011 1.06
56 Lipopolysaccharide injection induces relapses of experimental autoimmune encephalomyelitis in nontransgenic mice via bystander activation of autoreactive CD4+ cells. J Immunol 2005 1.06
57 Molecular changes in white matter adjacent to an active demyelinating lesion in early multiple sclerosis. Brain Pathol 2008 1.02
58 Wallerian degeneration: a major component of early axonal pathology in multiple sclerosis. Brain Pathol 2010 1.02
59 Differential upregulation of heme oxygenase-1 (HSP32) in glial cells after oxidative stress and in demyelinating disorders. J Mol Neurosci 2007 1.02
60 Cerebral involvement in axonal Charcot-Marie-Tooth neuropathy caused by mitofusin2 mutations. J Neurol 2008 1.01
61 Myelin-phagocytosing macrophages in isolated sciatic and optic nerves reveal a unique reactive phenotype. Glia 2008 1.00
62 Neuronal apoptosis in the dentate gyrus in humans with subarachnoid hemorrhage and cerebral hypoxia. Brain Pathol 2002 1.00
63 The role of cytokines and adhesion molecules in axon degeneration after peripheral nerve axotomy: a study in different knockout mice. Brain Res 2003 0.99
64 Diagnosis of inflammatory demyelination in biopsy specimens: a practical approach. Acta Neuropathol 2008 0.99
65 Nogo-A is a reliable oligodendroglial marker in adult human and mouse CNS and in demyelinated lesions. J Neuropathol Exp Neurol 2007 0.98
66 Axonal loss and neurofilament phosphorylation changes accompany lesion development and clinical progression in multiple sclerosis. Brain Pathol 2011 0.98
67 CD14 and TRIF govern distinct responsiveness and responses in mouse microglial TLR4 challenges by structural variants of LPS. Brain Behav Immun 2010 0.98
68 In toxic demyelination oligodendroglial cell death occurs early and is FAS independent. Neurobiol Dis 2009 0.98
69 Selective neuronal vulnerability following mild focal brain ischemia in the mouse. Brain Pathol 2003 0.96
70 TRPM3 is expressed in sphingosine-responsive myelinating oligodendrocytes. J Neurochem 2010 0.96
71 Atypical chronic lymphocytic inflammation with pontocerebellar perivascular enhancement responsive to steroids (CLIPPERS), primary angiitis of the CNS mimicking CLIPPERS or overlap syndrome? A case report. J Neurol Sci 2012 0.95
72 Natalizumab use in pediatric multiple sclerosis. Arch Neurol 2008 0.94
73 Early loss of oligodendrocytes in human and experimental neuromyelitis optica lesions. Acta Neuropathol 2013 0.94
74 Extensive acute axonal damage in pediatric multiple sclerosis lesions. Ann Neurol 2015 0.94
75 Favourable response to plasma exchange in tumefactive CNS demyelination with delayed B-cell response. Mult Scler 2011 0.93
76 Intracerebral human regulatory T cells: analysis of CD4+ CD25+ FOXP3+ T cells in brain lesions and cerebrospinal fluid of multiple sclerosis patients. PLoS One 2011 0.93
77 Late motor decline after accomplished remyelination: impact for progressive multiple sclerosis. Ann Neurol 2012 0.92
78 Oligodendrocyte injury in multiple sclerosis: a role for p53. J Neurochem 2003 0.92
79 Increased activin levels in cerebrospinal fluid of rabbits with bacterial meningitis are associated with activation of microglia. J Neurochem 2003 0.92
80 Intradural, extramedullary spinal sarcoidosis: report of a rare case and review of the literature. Spine J 2006 0.92
81 Streptococcus pneumoniae Infection aggravates experimental autoimmune encephalomyelitis via Toll-like receptor 2. Infect Immun 2006 0.91
82 Pathologic heterogeneity persists in early active multiple sclerosis lesions. Ann Neurol 2014 0.91
83 Multiple sclerosis - remyelination failure as a cause of disease progression. Histol Histopathol 2012 0.91
84 Isolated pituitary granuloma by atypical Mycobacterium in a nonimmunosuppressed woman. Clin Endocrinol (Oxf) 2002 0.91
85 Optic radiation damage in multiple sclerosis is associated with visual dysfunction and retinal thinning--an ultrahigh-field MR pilot study. Eur Radiol 2014 0.90
86 Neuroaxonal regeneration is more pronounced in early multiple sclerosis than in traumatic brain injury lesions. Brain Pathol 2012 0.90
87 Differential macrophage/microglia activation in neocortical EAE lesions in the marmoset monkey. Brain Pathol 2006 0.90
88 Primary angiitis of the CNS with pure spinal cord involvement: a case report. J Neurol 2010 0.90
89 Inhibition of Rho-dependent pathways by Clostridium botulinum C3 protein induces a proinflammatory profile in microglia. Glia 2008 0.90
90 Contrasting potential of nitric oxide and peroxynitrite to mediate oligodendrocyte injury in multiple sclerosis. Glia 2007 0.89
91 Over-expression of alpha-synuclein in the nervous system enhances axonal degeneration after peripheral nerve lesion in a transgenic mouse strain. J Neurochem 2010 0.89
92 Identification and functional characterization of a highly polymorphic region in the human TRAIL promoter in multiple sclerosis. J Neuroimmunol 2004 0.89
93 Increased expression of BDNF and proliferation of dentate granule cells after bacterial meningitis. J Neuropathol Exp Neurol 2005 0.88
94 Human glioma-initiating cells show a distinct immature phenotype resembling but not identical to NG2 glia. J Neuropathol Exp Neurol 2013 0.87
95 Propagation of spreading depression inversely correlates with cortical myelin content. Ann Neurol 2009 0.86
96 Lesion-associated expression of transforming growth factor-beta-2 in the rat nervous system: evidence for down-regulating the phagocytic activity of microglia and macrophages. Brain Pathol 2004 0.86
97 Increased neurogenesis after experimental Streptococcus pneumoniae meningitis. J Neurosci Res 2003 0.85
98 MicroRNA regulation in experimental autoimmune encephalomyelitis in mice and marmosets resembles regulation in human multiple sclerosis lesions. J Neuroimmunol 2012 0.85
99 Neuroprotective intervention by interferon-γ blockade prevents CD8+ T cell-mediated dendrite and synapse loss. J Exp Med 2013 0.85
100 Effects of pulmonary acid aspiration on the lungs and extra-pulmonary organs: a randomized study in pigs. Crit Care 2012 0.85
101 Fas (CD95/Apo-1)/Fas ligand expression in neonates with pontosubicular neuron necrosis. Pediatr Res 2002 0.85
102 Increased neurogenesis after hypoxic-ischemic encephalopathy in humans is age related. Acta Neuropathol 2009 0.84
103 Differential regulation of myelin phagocytosis by macrophages/microglia, involvement of target myelin, Fc receptors and activation by intravenous immunoglobulins. J Neurosci Res 2002 0.84
104 Persistence of immunopathological and radiological traits in multiple sclerosis. Arch Neurol 2008 0.84
105 Interplay between mechanisms of damage and repair in multiple sclerosis. J Neurol 2008 0.83
106 A woman with acute myelopathy in pregnancy: case outcome. BMJ 2009 0.83
107 Substantial early, but nonprogressive neuronal loss in multiple sclerosis (MS) spinal cord. Ann Neurol 2009 0.83
108 Additive microglia-mediated neuronal injury caused by amyloid-β and bacterial TLR agonists in murine neuron-microglia co-cultures quantified by an automated image analysis using cognition network technology. J Alzheimers Dis 2012 0.83
109 Type I interferon receptor signalling is induced during demyelination while its function for myelin damage and repair is redundant. Exp Neurol 2008 0.82
110 Necrotizing infundibulo-hypophysitis: an entity too rare to be true? Pituitary 2012 0.82
111 Autoimmune optic neuritis in the common marmoset monkey: comparison of visual evoked potentials with MRI and histopathology. Invest Ophthalmol Vis Sci 2008 0.82
112 Axonal injury, a neglected cause of CNS damage in bacterial meningitis. Neurology 2004 0.81
113 Differentiation of multiple sclerosis subtypes: implications for treatment. CNS Drugs 2002 0.81
114 Bacterial cytolysin during meningitis disrupts the regulation of glutamate in the brain, leading to synaptic damage. PLoS Pathog 2013 0.81
115 Oligodendroglia in cortical multiple sclerosis lesions decrease with disease progression, but regenerate after repeated experimental demyelination. Acta Neuropathol 2014 0.81
116 Pediatric onset multiple sclerosis: McDonald criteria 2010 and the contribution of spinal cord MRI. Mult Scler 2013 0.80
117 Limited TCF7L2 expression in MS lesions. PLoS One 2013 0.80
118 Advances in multiple sclerosis research in 2009. J Neurol 2010 0.80
119 Developmental maturation of innate immune cell function correlates with susceptibility to central nervous system autoimmunity. Eur J Immunol 2013 0.80
120 High chromosomal instability in brain metastases of colorectal carcinoma. Cancer Genet Cytogenet 2010 0.80
121 Puma, but not noxa is essential for oligodendroglial cell death. Glia 2013 0.79
122 The relative number of macrophages/microglia expressing macrophage colony-stimulating factor and its receptor decreases in multiple sclerosis lesions. Glia 2002 0.79
123 T cells can mediate viral clearance from ependyma but not from brain parenchyma in a major histocompatibility class I- and perforin-independent manner. Brain 2010 0.78
124 Molecular cytogenetics of malignant pheochromocytoma with cerebral metastasis. Cancer Genet Cytogenet 2010 0.78
125 Oxidized ATP inhibits T-cell-mediated autoimmunity. Eur J Immunol 2010 0.77
126 XIAP protects oligodendrocytes against cell death in vitro but has no functional role in toxic demyelination. Glia 2011 0.77
127 Oligodendroglial lineage cells express nuclear p57kip2 in multiple sclerosis lesions. Glia 2013 0.77
128 Brain derived neurotrophic factor does not act on adult human cerebral endothelial cells. Neurosci Lett 2002 0.77
129 Effects of intravenous immunoglobulins on T cell and oligodendrocyte apoptosis in high-dose antigen therapy in experimental autoimmune encephalomyelitis. Acta Neuropathol 2002 0.77
130 The activation pattern of macrophages in giant cell (temporal) arteritis and primary angiitis of the central nervous system. Neuropathology 2013 0.77
131 Spontaneous adrenal hemorrhage: a little-known complication of intracranial tumor surgery. Case report. J Neurosurg 2007 0.77
132 Follistatin does not influence the course of Escherichia coli K1 sepsis in a mouse model. Shock 2012 0.76
133 Increased Meningeal T and Plasma Cell Infiltration is Associated with Early Subpial Cortical Demyelination in Common Marmosets with Experimental Autoimmune Encephalomyelitis. Brain Pathol 2014 0.76
134 Fulminant tumefactive multiple sclerosis: therapeutic implications of histopathology. J Neurol 2008 0.75
135 High CCR5 expression in natalizumab-associated progressive multifocal leukoencephalopathy immune reconstitution inflammatory syndrome supports treatment with the CCR5 inhibitor maraviroc. Acta Neuropathol 2015 0.75
136 Biopsy findings of symptomatic cerebral X-linked adrenoleucodystrophy and histological differentiation from multiple sclerosis. Neuropathol Appl Neurobiol 2014 0.75
137 Diagnostic pitfall: optic neuritis mimicking optic nerve glioma. Neuropathology 2008 0.75
138 A 76-year-old woman with paraplegia. Brain Pathol 2010 0.75
139 CNS tumor 22 years after spinal neuroblastoma IV: diagnostic dilemma between recurrence and secondary malignancy. Pediatr Neurosurg 2009 0.75
140 Tyrphostin AG126 exerts neuroprotection in CNS inflammation by a dual mechanism. Glia 2015 0.75
141 Susceptibility to apoptosis in different murine muscle cell lines. J Muscle Res Cell Motil 2003 0.75
142 Remyelination After Cuprizone-Induced Demyelination Is Accelerated in Juvenile Mice. J Neuropathol Exp Neurol 2015 0.75
143 Fungal encephalitis in human autopsy cases is associated with extensive neuronal damage but only minimal repair. Neuropathol Appl Neurobiol 2014 0.75
144 Autoinflammatory grey matter lesions in humans: cortical encephalitis, clinical disorders, experimental models. Curr Opin Neurol 2012 0.75