PubRank

David A Wheeler

Author PubWeight™ 562.95‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A second generation human haplotype map of over 3.1 million SNPs. Nature 2007 85.39
2 Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 2007 75.09
3 Somatic mutations affect key pathways in lung adenocarcinoma. Nature 2008 30.02
4 Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature 2004 24.40
5 International network of cancer genome projects. Nature 2010 20.35
6 Genome-wide detection and characterization of positive selection in human populations. Nature 2007 17.27
7 Characterizing the cancer genome in lung adenocarcinoma. Nature 2007 16.48
8 Evolutionary and biomedical insights from the rhesus macaque genome. Science 2007 16.21
9 Whole-genome sequencing in a patient with Charcot-Marie-Tooth neuropathy. N Engl J Med 2010 13.57
10 Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science 2011 11.12
11 SNPdetector: a software tool for sensitive and accurate SNP detection. PLoS Comput Biol 2005 10.04
12 The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science 2010 9.61
13 Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution. Genome Res 2005 8.38
14 Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature 2012 8.31
15 The genome sequence of taurine cattle: a window to ruminant biology and evolution. Science 2009 8.23
16 Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence. Genome Biol 2002 8.07
17 Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds. Science 2009 7.64
18 Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome. Genome Res 2007 7.05
19 The DNA sequence of the human X chromosome. Nature 2005 6.97
20 The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective. Genome Biol 2002 5.80
21 A SNP discovery method to assess variant allele probability from next-generation resequencing data. Genome Res 2009 4.78
22 Deep resequencing reveals excess rare recent variants consistent with explosive population growth. Nat Commun 2010 4.39
23 Landscape of somatic retrotransposition in human cancers. Science 2012 4.37
24 Prediction of missense mutation functionality depends on both the algorithm and sequence alignment employed. Hum Mutat 2011 3.75
25 A common allele in RPGRIP1L is a modifier of retinal degeneration in ciliopathies. Nat Genet 2009 3.36
26 Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase. Cell 2011 3.27
27 TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum. Nat Genet 2011 3.06
28 Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. N Engl J Med 2015 3.00
29 Copy number variation detection in whole-genome sequencing data using the Bayesian information criterion. Proc Natl Acad Sci U S A 2011 2.72
30 Demographic histories and patterns of linkage disequilibrium in Chinese and Indian rhesus macaques. Science 2007 2.62
31 Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease. Am J Hum Genet 2009 2.50
32 Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers. Cancer Discov 2013 2.49
33 Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development. Mol Cell Biol 2005 2.32
34 Orphan nuclear receptor GCNF is required for the repression of pluripotency genes during retinoic acid-induced embryonic stem cell differentiation. Mol Cell Biol 2005 2.07
35 Integrated analyses of microRNAs demonstrate their widespread influence on gene expression in high-grade serous ovarian carcinoma. PLoS One 2012 1.76
36 Once-daily versus twice-daily lopinavir/ritonavir in antiretroviral-naive HIV-positive patients: a 48-week randomized clinical trial. J Infect Dis 2004 1.48
37 Genomic analysis of the nuclear receptor family: new insights into structure, regulation, and evolution from the rat genome. Genome Res 2004 1.38
38 Combined sequence-based and genetic mapping analysis of complex traits in outbred rats. Nat Genet 2013 1.30
39 Disruptive TP53 mutation is associated with aggressive disease characteristics in an orthotopic murine model of oral tongue cancer. Clin Cancer Res 2011 1.21
40 Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif. Nat Commun 2013 1.19
41 SubcloneSeeker: a computational framework for reconstructing tumor clone structure for cancer variant interpretation and prioritization. Genome Biol 2014 1.12
42 Novel microRNA candidates and miRNA-mRNA pairs in embryonic stem (ES) cells. PLoS One 2008 1.11
43 The finished DNA sequence of human chromosome 12. Nature 2006 1.08
44 Characterization of single-nucleotide variation in Indian-origin rhesus macaques (Macaca mulatta). BMC Genomics 2011 0.96
45 Effects of TP53 mutational status on gene expression patterns across 10 human cancer types. J Pathol 2014 0.94
46 Genome-wide analysis of binding sites and direct target genes of the orphan nuclear receptor NR2F1/COUP-TFI. PLoS One 2010 0.94
47 Genomic sequencing for cancer diagnosis and therapy. Annu Rev Med 2013 0.91
48 Initial testing (stage 1) of the PARP inhibitor BMN 673 by the pediatric preclinical testing program: PALB2 mutation predicts exceptional in vivo response to BMN 673. Pediatr Blood Cancer 2014 0.90
49 Identification of TP53 as an acute lymphocytic leukemia susceptibility gene through exome sequencing. Pediatr Blood Cancer 2012 0.86
50 Identification of genetic susceptibility to childhood cancer through analysis of genes in parallel. Cancer Genet 2011 0.84
51 Targeting iCre expression to murine progesterone receptor cell-lineages using bacterial artificial chromosome transgenesis. Genesis 2006 0.81
52 The DNA sequence, annotation and analysis of human chromosome 3. Nature 2006 0.78
53 Overview of the development of personalized genomic medicine and surgery. World J Surg 2011 0.77
54 Resequencing of IRS2 reveals rare variants for obesity but not fasting glucose homeostasis in Hispanic children. Physiol Genomics 2011 0.77
55 Common and rare variants of DAOA in bipolar disorder. Am J Med Genet B Neuropsychiatr Genet 2009 0.77
56 Building a comprehensive genomic program for hepatocellular carcinoma. World J Surg 2011 0.77
57 Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease. J Clin Invest 2016 0.77
58 Case series of patients with acute myeloid leukemia receiving hypomethylation therapy and retrospectively found to have IDH1 or IDH2 mutations. Leuk Lymphoma 2013 0.76
59 Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma. Cancer Cell 2016 0.76
60 A primer on a hepatocellular carcinoma bioresource bank using the cancer genome atlas guidelines: practical issues and pitfalls. World J Surg 2011 0.75
61 Pharmacogenetic characterization of naturally occurring germline NT5C1A variants to chemotherapeutic nucleoside analogs. Pharmacogenet Genomics 2016 0.75
62 Corrigendum: Whole-genome landscape of pancreatic neuroendocrine tumours. Nature 2017 0.75
63 Clinical and demographic features of HIV infection in El Salvador. Rev Panam Salud Publica 2003 0.75
64 Mini-extracorporeal Circulation and Off-pump Techniques Associated with Less Inflammatory Gene Expression as Compared to On-Pump in the 24-hour Postoperative Window Following Coronary Artery Bypass Grafting. J Cardiothorac Surg 2015 0.75
65 Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles. Cell Rep 2017 0.75