Published in Int Orthop on March 13, 2007
The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation. BMC Dev Biol (2008) 1.13
Joint loading modality: its application to bone formation and fracture healing. Br J Sports Med (2007) 1.07
Thyroid hormone-mediated growth and differentiation of growth plate chondrocytes involves IGF-1 modulation of beta-catenin signaling. J Bone Miner Res (2010) 1.06
The Regulatory Role of Signaling Crosstalk in Hypertrophy of MSCs and Human Articular Chondrocytes. Int J Mol Sci (2015) 0.86
IGF2-driven PI3 kinase and TGFbeta signaling pathways in chondrogenesis. Cell Biol Int (2008) 0.85
Mechano growth factor E peptide promotes osteoblasts proliferation and bone-defect healing in rabbits. Int Orthop (2010) 0.82
Elbow loading promotes longitudinal bone growth of the ulna and the humerus. J Bone Miner Metab (2011) 0.80
Hindlimb heating increases vascular access of large molecules to murine tibial growth plates measured by in vivo multiphoton imaging. J Appl Physiol (1985) (2013) 0.76
Circulating concentrations of insulin-like growth factor-I and risk of breast cancer. Lancet (1998) 10.11
Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study. Science (1998) 6.50
Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene. N Engl J Med (1996) 3.73
Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth. Dev Biol (2001) 3.13
Somatomedin: proposed designation for sulphation factor. Nature (1972) 2.63
Growth hormone and bone. Endocr Rev (1998) 2.28
Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabecular bone volume without increased osteoblast proliferation. Endocrinology (2000) 1.93
Igf1 promotes longitudinal bone growth by insulin-like actions augmenting chondrocyte hypertrophy. FASEB J (1999) 1.54
Bone lengthening in rabbits by callus distraction. The role of periosteum and endosteum. J Bone Joint Surg Br (1988) 1.45
Insulin-like growth factor regulates peak bone mineral density in mice by both growth hormone-dependent and -independent mechanisms. Endocrinology (2003) 1.43
In vivo actions of insulin-like growth factor-I (IGF-I) on bone formation and resorption in rats. Bone (1991) 1.19
Growth hormone induces multiplication of the slowly cycling germinal cells of the rat tibial growth plate. Proc Natl Acad Sci U S A (1992) 1.10
Three modes of ossification during distraction osteogenesis in the rat. J Bone Joint Surg Br (1997) 1.10
Differential effects of insulin-like growth factor I and growth hormone on developmental stages of rat growth plate chondrocytes in vivo. J Clin Invest (1994) 1.08
Serum insulin-like growth factors and insulin-like growth factor-binding proteins: clinical implications. Clin Chem (1999) 1.05
Extendible replacements of the proximal tibia for bone tumours. J Bone Joint Surg Br (2000) 0.96
Late orthopaedic sequelae following meningococcal septicaemia. A multicentre study. J Bone Joint Surg Br (2005) 0.95
Factors affecting callus distraction in limb lengthening. Clin Orthop Relat Res (1993) 0.90
Open fractures of the tibia in children. J Bone Joint Surg Am (1990) 0.89
Effect of locally infused IGF-I on femoral gene expression and bone turnover activity in old rats. J Bone Miner Res (1998) 0.87
Stimulation of trabecular bone formation by insulin-like growth factor I in adult ovariectomized rats. Am J Physiol (1994) 0.84
Growth changes in fractured long-bones: a study of 126 children. J Bone Joint Surg Br (1981) 0.84
Effects of acute 5-fluorouracil chemotherapy and insulin-like growth factor-I pretreatment on growth plate cartilage and metaphyseal bone in rats. Bone (2004) 0.82
Association of STAT4 with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in the Japanese population. Arthritis Rheum (2008) 1.51
An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors mSin3A/B. Biochem J (2003) 1.48
Incidence of lumbar spondylolysis in the general population in Japan based on multidetector computed tomography scans from two thousand subjects. Spine (Phila Pa 1976) (2009) 1.46
Cardiac rehabilitation reduces serum levels of oxidized low-density lipoprotein. Circ J (2014) 1.39
Athletes with unilateral spondylolysis are at risk of stress fracture at the contralateral pedicle and pars interarticularis: a clinical and biomechanical study. Am J Sports Med (2005) 1.36
Ubiquitin ligase Cbl-b is a negative regulator for insulin-like growth factor 1 signaling during muscle atrophy caused by unloading. Mol Cell Biol (2009) 1.27
Whole muscle length-tension relationships are accurately modeled as scaled sarcomeres in rabbit hindlimb muscles. J Biomech (2011) 1.20
JRAB/MICAL-L2 is a junctional Rab13-binding protein mediating the endocytic recycling of occludin. Mol Biol Cell (2006) 1.20
Pathomechanism of loss of elasticity and hypertrophy of lumbar ligamentum flavum in elderly patients with lumbar spinal canal stenosis. Spine (Phila Pa 1976) (2007) 1.18
Skeletal muscle gene expression in space-flown rats. FASEB J (2004) 1.18
The a3 isoform vacuolar type H⁺-ATPase promotes distant metastasis in the mouse B16 melanoma cells. Mol Cancer Res (2011) 1.17
SNPs in the KCNJ11-ABCC8 gene locus are associated with type 2 diabetes and blood pressure levels in the Japanese population. J Hum Genet (2007) 1.12
Osteoactivin upregulates expression of MMP-3 and MMP-9 in fibroblasts infiltrated into denervated skeletal muscle in mice. Am J Physiol Cell Physiol (2005) 1.10
Incidence and etiology of lumbar spondylolysis: review of the literature. J Orthop Sci (2010) 1.07
Mice lacking the EDB segment of fibronectin develop normally but exhibit reduced cell growth and fibronectin matrix assembly in vitro. Cancer Res (2002) 1.07
Replication of reported genetic associations of PADI4, FCRL3, SLC22A4 and RUNX1 genes with rheumatoid arthritis: results of an independent Japanese population and evidence from meta-analysis of East Asian studies. J Hum Genet (2007) 1.04
A variant of Desbuquois dysplasia characterized by advanced carpal bone age, short metacarpals, and elongated phalanges: report of seven cases. Am J Med Genet A (2010) 1.01
Hematoma in the cervical ligamentum flavum. Report of a case and review of the literature. Skeletal Radiol (2009) 1.01
Sp1 family of transcription factors regulates the human alpha2 (XI) collagen gene (COL11A2) in Saos-2 osteoblastic cells. J Bone Miner Res (2006) 1.01
MRI signal changes of the pedicle as an indicator for early diagnosis of spondylolysis in children and adolescents: a clinical and biomechanical study. Spine (Phila Pa 1976) (2006) 1.01
Conservative treatment for pediatric lumbar spondylolysis to achieve bone healing using a hard brace: what type and how long?: Clinical article. J Neurosurg Spine (2012) 1.01
Genomic structure and expression of the mouse ESET gene encoding an ERG-associated histone methyltransferase with a SET domain. Biochim Biophys Acta (2003) 1.00
Three successive stress fractures at the same vertebral level in an adolescent baseball player. Am J Sports Med (2003) 1.00
CANT1 mutation is also responsible for Desbuquois dysplasia, type 2 and Kim variant. J Med Genet (2010) 0.99
Ubiquitin ligase gene expression in healthy volunteers with 20-day bedrest. Muscle Nerve (2006) 0.98
A novel muscle biopsy clamp yields accurate in vivo sarcomere length values. J Biomech (2008) 0.97
State of the art: Transforaminal approach for percutaneous endoscopic lumbar discectomy under local anesthesia. J Med Invest (2014) 0.95
A novel type of EWS-CHOP fusion gene in myxoid liposarcoma. Biochem Biophys Res Commun (2006) 0.95
TRPV4-pathy manifesting both skeletal dysplasia and peripheral neuropathy: a report of three patients. Am J Med Genet A (2012) 0.95
Subchondral cysts in dysplastic osteoarthritic hips communicate with the joint space: analysis using three-dimensional computed tomography. Eur J Orthop Surg Traumatol (2012) 0.93
Prevalence and clinical features of Paget's disease of bone in Japan. J Bone Miner Metab (2006) 0.93
Minimally invasive technique for direct repair of pars interarticularis defects in adults using a percutaneous pedicle screw and hook-rod system. J Neurosurg Spine (2009) 0.93
Intramedullary schwannoma with calcification of the epiconus. Spine J (2009) 0.91
Overexpression of HMGA2-LPP fusion transcripts promotes expression of the alpha 2 type XI collagen gene. Biochem Biophys Res Commun (2005) 0.91
Conservative treatment for osteochondrosis of the humeral capitellum. Am J Sports Med (2008) 0.90
Association of single-nucleotide polymorphisms in the suppressor of cytokine signaling 2 (SOCS2) gene with type 2 diabetes in the Japanese. Genomics (2006) 0.90
Intrafamilial phenotypic diversity in multiple epiphyseal dysplasia associated with a COL9A2 mutation (EDM2). Clin Rheumatol (2006) 0.90
Natural history of extruded lumbar intervertebral disc herniation. J Med Invest (2002) 0.90
Correction of deformity and shortening due to post traumatic epiphyseal arrest by distraction osteogenesis. Arch Orthop Trauma Surg (2007) 0.90
Distinct expression of mast cell tryptase and protease activated receptor-2 in synovia of rheumatoid arthritis and osteoarthritis. Clin Rheumatol (2007) 0.90
Newly occurred L4 spondylolysis in the lumbar spine with pre-existence L5 spondylolysis among sports players: case reports and biomechanical analysis. Arch Orthop Trauma Surg (2008) 0.89
Association between single-nucleotide polymorphisms in the SEC8L1 gene, which encodes a subunit of the exocyst complex, and rheumatoid arthritis in a Japanese population. Arthritis Rheum (2005) 0.89
Adolescents with symptomatic laminolysis: report of two cases. J Orthop Traumatol (2010) 0.89
Lumbar-pelvic coordination in the sitting position. Gait Posture (2008) 0.88
Hemorrhagic facet cyst in the lumbar spine causing contralateral leg symptoms: a case report. Asian Spine J (2011) 0.88
Radiological features of lumbar spinal lesions in patients with rheumatoid arthritis with special reference to the changes around intervertebral discs. Spine J (2007) 0.88
Normal and spondylolytic pediatric spine movements with reference to instantaneous axis of rotation. Spine (Phila Pa 1976) (2002) 0.88
Continuous muscle stretch prevents disuse muscle atrophy and deterioration of its oxidative capacity in rat tail-suspension models. Am J Phys Med Rehabil (2004) 0.87
Ubiquitin ligase Cbl-b downregulates bone formation through suppression of IGF-I signaling in osteoblasts during denervation. J Bone Miner Res (2006) 0.87
Effects of monofilament nylon coated with basic fibroblast growth factor on endogenous intrasynovial flexor tendon healing. J Hand Surg Am (2006) 0.87
Vertebral forward slippage in immature lumbar spine occurs following epiphyseal separation and its occurrence is unrelated to disc degeneration: is the pediatric spondylolisthesis a physis stress fracture of vertebral body? Spine (Phila Pa 1976) (2004) 0.87
Locally administered zoledronic Acid therapy for giant cell tumor of bone. Orthopedics (2011) 0.87
Open treatment of syndactyly of the foot. Scand J Plast Reconstr Surg Hand Surg (2003) 0.86
Treatment of knee osteoarthritis associated with extraarticular varus deformity of the femur: staged total knee arthroplasty following corrective osteotomy. J Orthop Sci (2006) 0.86
No evidence for association of the ENPP1 (PC-1) K121Q variant with risk of type 2 diabetes in a Japanese population. J Hum Genet (2006) 0.85
Influence of age on scapulo-thoracic orientation. Clin Biomech (Bristol, Avon) (2004) 0.85
The value of using radiographic criteria for the treatment of persistent symptomatic olecranon physis in adolescent throwing athletes. Am J Sports Med (2009) 0.85
Long-term outcomes of lumbar posterior apophyseal end-plate lesions in children and adolescents. J Bone Joint Surg Am (2012) 0.84
Significance of magnetic resonance imaging signal change in the pedicle in the management of pediatric lumbar spondylolysis. Spine (Phila Pa 1976) (2010) 0.84
Specificity of fusion genes in adipocytic tumors. Anticancer Res (2010) 0.84
Myxoid liposarcoma with EWS-CHOP type 1 fusion gene. Anticancer Res (2010) 0.84
Long-term outcome of severe stroke patients: is the ADL status at discharge from a stroke center indicative of the long-term outcome? J Med Invest (2011) 0.84
MRI changes of the spinal subdural space after lumbar spine surgeries: report of two cases. Asian Spine J (2011) 0.84
Genetic association between the PRKCH gene encoding protein kinase Ceta isozyme and rheumatoid arthritis in the Japanese population. Arthritis Rheum (2007) 0.84
Treatment of dysplastic osteoarthritis with labral tear by Chiari pelvic osteotomy: outcomes after more than 10 years follow-up. Arch Orthop Trauma Surg (2007) 0.83
Myxoid liposarcoma-associated EWSR1-DDIT3 selectively represses osteoblastic and chondrocytic transcription in multipotent mesenchymal cells. PLoS One (2012) 0.83
Mirror foot: treatment of three cases and review of the literature. J Child Orthop (2009) 0.83
Evolution of understanding of genetics of Paget's disease of bone and related diseases. J Bone Miner Metab (2004) 0.83
Early ambulation after total knee arthroplasty prevents patients with osteoarthritis and rheumatoid arthritis from developing postoperative higher levels of D-dimer. J Med Invest (2010) 0.83
Causes of radiculopathy in young athletes with spondylolysis. Am J Sports Med (2009) 0.83
The pathogenesis of slippage and deformity in the pediatric lumbar spine: a radiographic and histologic study using a new rat in vivo model. Spine (Phila Pa 1976) (2003) 0.83
Efficacy, tolerability, and safety of risedronate in Japanese patients with Paget's disease of bone. J Bone Miner Metab (2010) 0.83
Asynchronous progressive diaphyseal dysplasia. Mod Rheumatol (2005) 0.82