Published in Immunology on April 13, 2007
New insights into the pathogenesis and detection of Mycoplasma pneumoniae infections. Future Microbiol (2008) 2.00
Transcriptional regulation of MG_149, an osmoinducible lipoprotein gene from Mycoplasma genitalium. Mol Microbiol (2011) 1.52
The expression and functions of toll-like receptors in atherosclerosis. Mediators Inflamm (2010) 1.07
Mycoplasma pneumoniae-derived lipopeptides induce acute inflammatory responses in the lungs of mice. Infect Immun (2007) 1.04
A triacylated lipoprotein from Mycoplasma genitalium activates NF-kappaB through Toll-like receptor 1 (TLR1) and TLR2. Infect Immun (2008) 1.00
Mycoplasma suppression of THP-1 Cell TLR responses is corrected with antibiotics. PLoS One (2010) 0.99
Novel bacterial lipoprotein structures conserved in low-GC content gram-positive bacteria are recognized by Toll-like receptor 2. J Biol Chem (2012) 0.96
Induction of IL-8 by Mycoplasma pneumoniae membrane in BEAS-2B cells. Am J Physiol Lung Cell Mol Physiol (2008) 0.89
Cytoadherence-dependent induction of inflammatory responses by Mycoplasma pneumoniae. Immunology (2011) 0.89
Toll-like receptor 1 polymorphisms and associated outcomes in sepsis after traumatic injury: a candidate gene association study. Ann Surg (2014) 0.86
Toll-like receptors in atherosclerosis. Int J Mol Sci (2013) 0.86
TLR2 mediates immunity to experimental cysticercosis. Int J Biol Sci (2011) 0.85
Reactive oxygen species mediate Jak2/Stat3 activation and IL-8 expression in pulmonary epithelial cells stimulated with lipid-associated membrane proteins from Mycoplasma pneumoniae. Inflamm Res (2012) 0.84
Mycoplasma lipoproteins and Toll-like receptors. J Zhejiang Univ Sci B (2009) 0.83
Vaccination of BALB/c mice with an avirulent Mycoplasma pneumoniae P30 mutant results in disease exacerbation upon challenge with a virulent strain. Infect Immun (2012) 0.81
Cytadherence of Mycoplasma pneumoniae induces inflammatory responses through autophagy and toll-like receptor 4. Infect Immun (2014) 0.81
Mycoplasma gallisepticum lipid associated membrane proteins up-regulate inflammatory genes in chicken tracheal epithelial cells via TLR-2 ligation through an NF-κB dependent pathway. PLoS One (2014) 0.80
SHP-1 as a critical regulator of Mycoplasma pneumoniae-induced inflammation in human asthmatic airway epithelial cells. J Immunol (2012) 0.79
Insights into the pathogenesis of Mycoplasma pneumoniae (Review). Mol Med Rep (2016) 0.77
Inflammation-inducing Factors of Mycoplasma pneumoniae. Front Microbiol (2016) 0.77
Interaction of Mycoplasma gallisepticum with Chicken Tracheal Epithelial Cells Contributes to Macrophage Chemotaxis and Activation. Infect Immun (2015) 0.76
Multiple organ dysfunction syndrome associated with Mycoplasma pneumoniae infection. Braz J Microbiol (2012) 0.75
Interaction of Mycoplasma hominis PG21 with human dendritic cells: IL-23-inducing mycoplasmal lipoproteins and inflammasome activation of the cell. J Bacteriol (2017) 0.75
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science (1998) 37.15
Toll-like receptor signalling. Nat Rev Immunol (2004) 34.74
The minimal gene complement of Mycoplasma genitalium. Science (1995) 32.41
A Toll-like receptor recognizes bacterial DNA. Nature (2000) 26.34
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity (1999) 17.40
Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J Immunol (1999) 16.86
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature (2001) 14.24
Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae. Nucleic Acids Res (1996) 10.46
MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways. Mol Cell (1998) 8.73
Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science (1999) 8.63
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature (1999) 8.50
Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. Science (1999) 7.75
Error-tolerant identification of peptides in sequence databases by peptide sequence tags. Anal Chem (1994) 7.04
A phylogenetic analysis of the mycoplasmas: basis for their classification. J Bacteriol (1989) 6.66
Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. J Biol Chem (1999) 5.81
Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins. J Immunol (2002) 5.48
Discrimination of bacterial lipoproteins by Toll-like receptor 6. Int Immunol (2001) 5.36
The Toll-receptor family and control of innate immunity. Curr Opin Immunol (1999) 3.08
TLR6: A novel member of an expanding toll-like receptor family. Gene (1999) 2.55
Detection of Mycoplasma pneumoniae in the airways of adults with chronic asthma. Am J Respir Crit Care Med (1998) 2.45
The CD14 ligands lipoarabinomannan and lipopolysaccharide differ in their requirement for Toll-like receptors. J Immunol (1999) 2.44
Isolation, structure elucidation, and synthesis of a macrophage stimulatory lipopeptide from Mycoplasma fermentans acting at picomolar concentration. J Exp Med (1997) 2.33
The complete genomic sequence of Mycoplasma penetrans, an intracellular bacterial pathogen in humans. Nucleic Acids Res (2002) 2.17
ADP-ribosylating and vacuolating cytotoxin of Mycoplasma pneumoniae represents unique virulence determinant among bacterial pathogens. Proc Natl Acad Sci U S A (2006) 2.00
Toll-like receptor 6-independent signaling by diacylated lipopeptides. Eur J Immunol (2005) 1.84
Interactions between mycoplasma lipoproteins and the host immune system. Trends Microbiol (1999) 1.58
Differential recognition of structural details of bacterial lipopeptides by toll-like receptors. Eur J Immunol (2002) 1.57
Isolation of Mycoplasma pneumoniae from asthmatic patients. Ann Allergy (1993) 1.42
Structure and specific activity of macrophage-stimulating lipopeptides from Mycoplasma hyorhinis. Infect Immun (1998) 1.38
TLR2 signaling is critical for Mycoplasma pneumoniae-induced airway mucin expression. J Immunol (2005) 1.26
Stimulation of human Toll-like receptor (TLR) 2 and TLR6 with membrane lipoproteins of Mycoplasma fermentans induces apoptotic cell death after NF-kappa B activation. Cell Microbiol (2004) 1.25
A dipalmitoylated lipoprotein from Mycoplasma pneumoniae activates NF-kappa B through TLR1, TLR2, and TLR6. J Immunol (2005) 1.23
Induced mouse spleen B-cell proliferation and secretion of immunoglobulin by lipid-associated membrane proteins of Mycoplasma fermentans incognitus and Mycoplasma penetrans. Infect Immun (1994) 1.12
Lipid-associated membrane proteins of Mycoplasma fermentans and M. penetrans activate human immunodeficiency virus long-terminal repeats through Toll-like receptors. Immunology (2004) 1.08
The Mycoplasma-derived lipopeptide MALP-2 is a potent mucosal adjuvant. Eur J Immunol (2002) 1.04
The Toll-like receptor ligand MALP-2 stimulates dendritic cell maturation and modulates proteasome composition and activity. Eur J Immunol (2004) 0.95
Lipid extract of Mycoplasma penetrans proteinase K-digested lipid-associated membrane proteins rapidly activates NF-kappaB and activator protein 1. Infect Immun (1999) 0.91
Purification of Mycoplasma gallisepticum membrane proteins p52, p67 (pMGA), and p77 by high-performance liquid chromatography. Protein Expr Purif (1996) 0.89
Selective acylation of plasma membrane proteins of Mycoplasma mycoides subsp. mycoides SC, the contagious bovine pleuropneumonia agent. Curr Microbiol (1996) 0.88
In vivo immunomodulation by Mycoplasma fermentans membrane lipoprotein. Curr Microbiol (2004) 0.83
The Mycoplasma-derived macrophage-activating 2-kilodalton lipopeptide triggers global immune activation on nasal mucosa-associated lymphoid tissues. Infect Immun (2004) 0.79
Antimicrobial activity and stability to proteolysis of small linear cationic peptides with D-amino acid substitutions. Microbiol Immunol (2002) 1.24
A dipalmitoylated lipoprotein from Mycoplasma pneumoniae activates NF-kappa B through TLR1, TLR2, and TLR6. J Immunol (2005) 1.23
Ureaplasma parvum lipoproteins, including MB antigen, activate NF-{kappa}B through TLR1, TLR2 and TLR6. Microbiology (2008) 1.14
Sodium butyrate up-regulates cathelicidin gene expression via activator protein-1 and histone acetylation at the promoter region in a human lung epithelial cell line, EBC-1. Mol Immunol (2006) 1.10
A novel secreted protease from Pseudomonas aeruginosa activates NF-kappaB through protease-activated receptors. Cell Microbiol (2008) 1.10
Lipid-associated membrane proteins of Mycoplasma fermentans and M. penetrans activate human immunodeficiency virus long-terminal repeats through Toll-like receptors. Immunology (2004) 1.08
Mycoplasma pneumoniae-derived lipopeptides induce acute inflammatory responses in the lungs of mice. Infect Immun (2007) 1.04
Serratia marcescens serralysin induces inflammatory responses through protease-activated receptor 2. Infect Immun (2006) 1.04
A triacylated lipoprotein from Mycoplasma genitalium activates NF-kappaB through Toll-like receptor 1 (TLR1) and TLR2. Infect Immun (2008) 1.00
Novel bacterial lipoprotein structures conserved in low-GC content gram-positive bacteria are recognized by Toll-like receptor 2. J Biol Chem (2012) 0.96
Cytoadherence-dependent induction of inflammatory responses by Mycoplasma pneumoniae. Immunology (2011) 0.89
Impaired capsular polysaccharide is relevant to enhanced biofilm formation and lower virulence in Streptococcus pneumoniae. J Infect Chemother (2012) 0.87
Effects of Ureaplasma parvum lipoprotein multiple-banded antigen on pregnancy outcome in mice. J Reprod Immunol (2013) 0.86
Caveolin-1 is a competitive inhibitor of heme oxygenase-1 (HO-1) with heme: identification of a minimum sequence in caveolin-1 for binding to HO-1. Biochemistry (2011) 0.84
Evaluation of QT interval using a linear model in individual cynomolgus monkeys. J Pharmacol Toxicol Methods (2006) 0.84
Opposing roles of activator protein-1 and CCAAT/enhancer binding protein beta in the regulation of inducible granulysin gene expression in a human monocytic cell line, THP-1. Immunology (2002) 0.84
Reactive oxygen species mediate Jak2/Stat3 activation and IL-8 expression in pulmonary epithelial cells stimulated with lipid-associated membrane proteins from Mycoplasma pneumoniae. Inflamm Res (2012) 0.84
Cooperation between LepA and PlcH contributes to the in vivo virulence and growth of Pseudomonas aeruginosa in mice. Infect Immun (2010) 0.83
Antimicrobial activity of inducible human beta defensin-2 against Mycoplasma pneumoniae. Curr Microbiol (2006) 0.81
EprS, an autotransporter protein of Pseudomonas aeruginosa, possessing serine protease activity induces inflammatory responses through protease-activated receptors. Cell Microbiol (2013) 0.79
Glycoglycerolipid from the membranes of Acholeplasma laidlawii binds to human immunodeficiency virus-1 (HIV-1) and accelerates its entry into cells. Curr Microbiol (2004) 0.79
Mycoplasma pneumoniae infection induces a neutrophil-derived antimicrobial peptide, cathelin-related antimicrobial peptide. Microbiol Immunol (2011) 0.78
Protein phosphatase 2A dephosphorylates phosphoserines in nucleocytoplasmic shuttling and secretion of high mobility group box 1. J Biochem (2013) 0.78
Left ventricular volume and function in cynomolgus monkeys using real-time three-dimensional echocardiography. J Med Primatol (2007) 0.78
Modifications on amphiphilicity and cationicity of unnatural amino acid containing peptides for the improvement of antimicrobial activity against pathogenic bacteria. J Pept Sci (2010) 0.77
Interactions of a small linear cationic peptide with lipopolysaccharide and lipoteichoic acid. Kurume Med J (2003) 0.77
Conditional expression of liver-enriched transcriptional activator protein augments Acholeplasma laidlawii-induced granulysin gene expression in a human monocytic cell line, THP-1. Immunology (2005) 0.77
Fas-mediated lysis of target cell by IL-2 treated cytotoxic T lymphocytes. Kurume Med J (2002) 0.75
Can an individualized and comprehensive care strategy improve urinary incontinence (UI) among nursing home residents? Arch Gerontol Geriatr (2008) 0.75