Regulation of matrix metalloproteinase-2 (MMP-2) activity by phosphorylation.

The regulatory crosstalk between kinases and proteases in cancer. Nat Rev Cancer (2010) 1.80

Acute actions and novel targets of matrix metalloproteinases in the heart and vasculature. Br J Pharmacol (2007) 1.33

SIRT1 enhances matrix metalloproteinase-2 expression and tumor cell invasion in prostate cancer cells. Prostate (2012) 1.00

Matrix metalloproteinases as therapeutic targets for stroke. Brain Res (2015) 0.97

MMPs 2 and 9 are essential for coronary collateral growth and are prominently regulated by p38 MAPK. J Mol Cell Cardiol (2011) 0.96

Post-treatment with amphetamine enhances reinnervation of the ipsilateral side cortex in stroke rats. Neuroimage (2011) 0.95

A key role of microRNA-29b for the suppression of colon cancer cell migration by American ginseng. PLoS One (2013) 0.95

Melanoma biomolecules: independently identified but functionally intertwined. Front Oncol (2013) 0.95

Inhibition of matrix metalloproteinase-2 by PARP inhibitors. Biochem Biophys Res Commun (2009) 0.95

Association of sepsis-related mortality with early increase of TIMP-1/MMP-9 ratio. PLoS One (2014) 0.93

Thoracic aortic dissection: are matrix metalloproteinases involved? Vascular (2009) 0.93

The relationship between the MMP system, adrenoceptors and phosphoprotein phosphatases. Br J Pharmacol (2012) 0.91

Reactive oxygen species released from hypoxic hepatocytes regulates MMP-2 expression in hepatic stellate cells. Int J Mol Sci (2011) 0.89

Myocardial matrix metalloproteinase-2: inside out and upside down. J Mol Cell Cardiol (2014) 0.88

Artemether combined with shRNA interference of vascular cell adhesion molecule-1 significantly inhibited the malignant biological behavior of human glioma cells. PLoS One (2013) 0.83

Ischemia/reperfusion-induced myosin light chain 1 phosphorylation increases its degradation by matrix metalloproteinase 2. FEBS J (2012) 0.83

Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis. Matrix Biol (2015) 0.82

EMMPRIN-mediated induction of uterine and vascular matrix metalloproteinases during pregnancy and in response to estrogen and progesterone. Biochem Pharmacol (2013) 0.81

Phosphorylation status of 72 kDa MMP-2 determines its structure and activity in response to peroxynitrite. PLoS One (2013) 0.80

Ecto-protein kinases and phosphatases: an emerging field for translational medicine. J Transl Med (2014) 0.80

Dimerization of matrix metalloproteinase-2 (MMP-2): functional implication in MMP-2 activation. J Biol Chem (2012) 0.80

A Prodrug-type, MMP-2-targeting Nanoprobe for Tumor Detection and Imaging. Theranostics (2015) 0.79

Heterogeneity of serum gelatinases MMP-2 and MMP-9 isoforms and charge variants. J Cell Mol Med (2014) 0.78

Intracellular regulation of matrix metalloproteinase-2 activity: new strategies in treatment and protection of heart subjected to oxidative stress. Scientifica (Cairo) (2013) 0.77

Metalloproteinases: key and common mediators of multiple GPCRs and candidate therapeutic targets in models of hypertensive cardiac disease. Drug Discov Today Dis Models (2012) 0.77

Two-dimensional zymography differentiates gelatinase isoforms in stimulated microglial cells and in brain tissues of acute brain injuries. PLoS One (2015) 0.77

Proteomic database mining opens up avenues utilizing extracellular protein phosphorylation for novel therapeutic applications. J Transl Med (2015) 0.77

Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses. Aging (Albany NY) (2016) 0.77

Proteolytic Cleavage of AMPKα and Intracellular MMP9 Expression Are Both Required for TLR4-Mediated mTORC1 Activation and HIF-1α Expression in Leukocytes. J Immunol (2015) 0.77

Helicobacter pylori-elicited induction in gastric mucosal matrix metalloproteinase-9 (MMP-9) release involves ERK-dependent cPLA2 activation and its recruitment to the membrane-localized Rac1/p38 complex. Inflammopharmacology (2016) 0.76

PRL-3 mediates the protein maturation of ULBP2 by regulating the tyrosine phosphorylation of HSP60. J Immunol (2015) 0.76

Suppression of the invasive potential of Glioblastoma cells by mTOR inhibitors involves modulation of NFκB and PKC-α signaling. Sci Rep (2016) 0.76

Expression of soluble and functional full-length human matrix metalloproteinase-2 in Escherichia coli. J Biotechnol (2011) 0.76

Ischemia/Reperfusion Injury following Acute Myocardial Infarction: A Critical Issue for Clinicians and Forensic Pathologists. Mediators Inflamm (2017) 0.75

Oxidative DNA Damage Mediated by Intranuclear MMP Activity Is Associated with Neuronal Apoptosis in Ischemic Stroke. Oxid Med Cell Longev (2016) 0.75

A Naturally Occurring Antibody Fragment Neutralizes Infectivity of Diverse Infectious Agents. Sci Rep (2016) 0.75

iTRAQ proteomic analysis of extracellular matrix remodeling in aortic valve disease. Sci Rep (2015) 0.75

Matrix metalloproteinases in exercise and obesity. Vasc Health Risk Manag (2016) 0.75

Tissue- and cell-specific co-localization of intracellular gelatinolytic activity and matrix metalloproteinase 2. J Histochem Cytochem (2013) 0.75

Towards an improved investment approach for an effective response to HIV/AIDS. Lancet (2011) 11.89

Cost-effectiveness of HIV treatment in resource-poor settings--the case of Côte d'Ivoire. N Engl J Med (2006) 5.62

Enhancing the quality of life of dementia caregivers from different ethnic or racial groups: a randomized, controlled trial. Ann Intern Med (2006) 4.13

Long-term mortality and quality of life after prolonged mechanical ventilation. Crit Care Med (2004) 3.36

Patients' recollections of stressful experiences while receiving prolonged mechanical ventilation in an intensive care unit. Crit Care Med (2002) 2.91

A motivational theory of life-span development. Psychol Rev (2010) 2.89

Effect of multicomponent interventions on caregiver burden and depression: the REACH multisite initiative at 6-month follow-up. Psychol Aging (2003) 2.70

Depression and Bipolar Support Alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in late life. Arch Gen Psychiatry (2003) 2.70

Review and meta-analysis of couple-oriented interventions for chronic illness. Ann Behav Med (2010) 2.47

The Resources for Enhancing Alzheimer's Caregiver Health (REACH): project design and baseline characteristics. Psychol Aging (2003) 2.36

Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia-reperfusion injury and preconditioning. Br J Pharmacol (2003) 2.26

Intracellular action of matrix metalloproteinase-2 accounts for acute myocardial ischemia and reperfusion injury. Circulation (2002) 2.25

The course of functional decline in older people with persistently elevated depressive symptoms: longitudinal findings from the Cardiovascular Health Study. J Am Geriatr Soc (2005) 2.20

Is it beneficial to involve a family member? A meta-analysis of psychosocial interventions for chronic illness. Health Psychol (2004) 2.14

Adaptive self-regulation of unattainable goals: goal disengagement, goal reengagement, and subjective well-being. Pers Soc Psychol Bull (2003) 2.13

Isolated heart perfusion according to Langendorff---still viable in the new millennium. J Pharmacol Toxicol Methods (2006) 2.06

Trust in the health care system and the use of preventive health services by older black and white adults. Am J Public Health (2008) 2.04

Family caregivers' strains: comparative analysis of cancer caregiving with dementia, diabetes, and frail elderly caregiving. J Aging Health (2008) 1.94

Prevalence and outcomes of caregiving after prolonged (> or =48 hours) mechanical ventilation in the ICU. Chest (2004) 1.91

Risk factors for potentially harmful informal caregiver behavior. J Am Geriatr Soc (2005) 1.81

Titin is a target of matrix metalloproteinase-2: implications in myocardial ischemia/reperfusion injury. Circulation (2010) 1.80

Caregiving behavior is associated with decreased mortality risk. Psychol Sci (2009) 1.76

Caregiver-specific outcomes in antidementia clinical drug trials: a systematic review and meta-analysis. J Am Geriatr Soc (2005) 1.75

Effect of an in-home occupational and physical therapy intervention on reducing mortality in functionally vulnerable older people: preliminary findings. J Am Geriatr Soc (2006) 1.71

Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death. J Clin Invest (2002) 1.70

Preparedness for the death of a loved one and mental health in bereaved caregivers of patients with dementia: findings from the REACH study. J Palliat Med (2006) 1.69

Matrix metalloproteinase-2 (MMP-2) is present in the nucleus of cardiac myocytes and is capable of cleaving poly (ADP-ribose) polymerase (PARP) in vitro. FASEB J (2004) 1.69

Patient-specific, time-varying predictors of post-ICU informal caregiver burden: the caregiver outcomes after ICU discharge project. Chest (2009) 1.69

Benefit-finding in the cancer caregiving experience. Psychosom Med (2007) 1.67

Informal caregiver burden among survivors of prolonged mechanical ventilation. Am J Respir Crit Care Med (2006) 1.64

The association of race and socioeconomic status with cardiovascular disease indicators among older adults in the health, aging, and body composition study. J Gerontol B Psychol Sci Soc Sci (2002) 1.58

Interpersonal effects of suffering in older adult caregiving relationships. Psychol Aging (2009) 1.56

Degradation of myosin light chain in isolated rat hearts subjected to ischemia-reperfusion injury: a new intracellular target for matrix metalloproteinase-2. Circulation (2005) 1.56

Depression and distress predict time to cardiovascular disease in dementia caregivers. Health Psychol (2007) 1.55

Identification of palmitoylated mitochondrial proteins using a bio-orthogonal azido-palmitate analogue. FASEB J (2007) 1.55

Caregiving at the end of life. J Palliat Med (2006) 1.54

Transitions in spousal caregiving. Gerontologist (2003) 1.54

Clinical research and the stages of dying. Omega (Westport) (1974) 1.53

Using a new taxonomy to combine the uncombinable: integrating results across diverse interventions. Psychol Aging (2003) 1.53

NAD+ biosynthesis ameliorates a zebrafish model of muscular dystrophy. PLoS Biol (2012) 1.53

Nitrosative stress and pharmacological modulation of heart failure. Trends Pharmacol Sci (2005) 1.53

The Life Engagement Test: assessing purpose in life. J Behav Med (2006) 1.50

Financial exploitation and psychological mistreatment among older adults: differences between African Americans and non-African Americans in a population-based survey. Gerontologist (2010) 1.49

Improving quality of life in men with prostate cancer: a randomized controlled trial of group education interventions. Health Psychol (2003) 1.48

The myosin co-chaperone UNC-45 is required for skeletal and cardiac muscle function in zebrafish. Dev Biol (2006) 1.46

Patterns of depressive symptoms in caregivers of mechanically ventilated critically ill adults from intensive care unit admission to 2 months postintensive care unit discharge: a pilot study. Crit Care Med (2012) 1.45

Preparing family caregivers for death and bereavement. Insights from caregivers of terminally ill patients. J Pain Symptom Manage (2008) 1.42

Bioactive contaminants leach from disposable laboratory plasticware. Science (2008) 1.42

The prognostic significance of inspiratory capacity in pulmonary arterial hypertension. Respiration (2014) 1.41

An evidence-based medicine elective course to improve student performance in advanced pharmacy practice experiences. Am J Pharm Educ (2011) 1.41

Postresuscitation administration of doxycycline preserves cardiac contractile function in hypoxia-reoxygenation injury of newborn piglets*. Crit Care Med (2014) 1.40

Matrix metalloproteinase-2 and myocardial oxidative stress injury: beyond the matrix. Cardiovasc Res (2009) 1.39

The myxoma poxvirus protein, M11L, prevents apoptosis by direct interaction with the mitochondrial permeability transition pore. J Exp Med (2002) 1.39

Prevalence and correlates of anxiety symptoms in well-functioning older adults: findings from the health aging and body composition study. J Am Geriatr Soc (2003) 1.38

Raising the bar: PEPFAR and new paradigms for global health. J Acquir Immune Defic Syndr (2012) 1.37

Preparing caregivers for the death of a loved one: a theoretical framework and suggestions for future research. J Palliat Med (2006) 1.35

Positive and negative religious coping and well-being in women with breast cancer. J Palliat Med (2009) 1.34

Development of the risk appraisal measure: a brief screen to identify risk areas and guide interventions for dementia caregivers. J Am Geriatr Soc (2009) 1.33

Antioxidant vitamin C improves endothelial function in obstructive sleep apnea. Am J Respir Crit Care Med (2006) 1.33

A methodology for describing and decomposing complex psychosocial and behavioral interventions. Psychol Aging (2003) 1.32

Older spouses' perceptions of partners' chronic arthritis pain: implications for spousal responses, support provision, and caregiving experiences. Psychol Aging (2006) 1.32

Rapid detection, discovery, and identification of post-translationally myristoylated proteins during apoptosis using a bio-orthogonal azidomyristate analog. FASEB J (2007) 1.31

Palmitoylated TMX and calnexin target to the mitochondria-associated membrane. EMBO J (2011) 1.31

Peroxynitrite-induced myocardial injury is mediated through matrix metalloproteinase-2. Cardiovasc Res (2002) 1.30

Positive aspects of caregiving and adaptation to bereavement. Psychol Aging (2004) 1.28

Activation and modulation of 72kDa matrix metalloproteinase-2 by peroxynitrite and glutathione. Biochem Pharmacol (2008) 1.28

Health stresses and depressive symptomatology in the elderly: the importance of health engagement control strategies. Health Psychol (2002) 1.27

Hospital costs in patients receiving prolonged mechanical ventilation: does age have an impact? Crit Care Med (2003) 1.26

Post-translational myristoylation: Fat matters in cellular life and death. Biochimie (2010) 1.25

The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes. Proc Natl Acad Sci U S A (2009) 1.24

Poly(ADP-Ribose) polymerase inhibition reduces reperfusion injury after heart transplantation. Circ Res (2002) 1.23

Enhanced NO and superoxide generation in dysfunctional hearts from endotoxemic rats. Am J Physiol Heart Circ Physiol (2002) 1.23

Association of enjoyable leisure activities with psychological and physical well-being. Psychosom Med (2009) 1.22

Reframing HIV care: putting people at the centre of antiretroviral delivery. Trop Med Int Health (2015) 1.20

Rapid and selective detection of fatty acylated proteins using omega-alkynyl-fatty acids and click chemistry. J Lipid Res (2009) 1.20

Interventions to enhance physical and psychological functioning among younger women who are ending nonhormonal adjuvant treatment for early-stage breast cancer. J Clin Oncol (2005) 1.18

Guiding research in family care: a new approach to oncology caregiving. Psychooncology (2008) 1.16

Depressive symptoms in older African-American and white adults with functional difficulties: the role of control strategies. J Am Geriatr Soc (2007) 1.14

N-myristoyltransferase 1 is essential in early mouse development. J Biol Chem (2005) 1.14

Matrix metalloproteinase-7 and ADAM-12 (a disintegrin and metalloproteinase-12) define a signaling axis in agonist-induced hypertension and cardiac hypertrophy. Circulation (2009) 1.13

Posttranslational myristoylation of caspase-activated p21-activated protein kinase 2 (PAK2) potentiates late apoptotic events. Proc Natl Acad Sci U S A (2006) 1.13

Making sense of mild cognitive impairment: a qualitative exploration of the patient's experience. Gerontologist (2006) 1.12

Socioeconomic position and incident mobility impairment in the Cardiovascular Health Study. BMC Geriatr (2007) 1.10

Matrix metalloproteinase-2 degrades the cytoskeletal protein alpha-actinin in peroxynitrite mediated myocardial injury. J Mol Cell Cardiol (2007) 1.09

Palmitoylation is the switch that assigns calnexin to quality control or ER Ca2+ signaling. J Cell Sci (2013) 1.08

Matrix metalloproteinase-2 mediates cytokine-induced myocardial contractile dysfunction. Cardiovasc Res (2003) 1.08

Obstructive sleep apnea, oxidative stress and cardiovascular disease: lessons from animal studies. Oxid Med Cell Longev (2013) 1.07

Hyperlipidemia attenuates the infarct size-limiting effect of ischemic preconditioning: role of matrix metalloproteinase-2 inhibition. J Pharmacol Exp Ther (2005) 1.07