Published in J Am Chem Soc on April 18, 2007
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Spirastrellolide B reveals the absolute configuration of the spirastrellolide macrolide core. J Am Chem Soc (2007) 1.18
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Use of experimental design for the optimization of the production of new secondary metabolites by two Penicillium species. J Nat Prod (2010) 1.15
Sintokamides A to E, chlorinated peptides from the sponge Dysidea sp. that inhibit transactivation of the N-terminus of the androgen receptor in prostate cancer cells. Org Lett (2008) 1.15
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Tauramamide, a lipopeptide antibiotic produced in culture by Brevibacillus laterosporus isolated from a marine habitat: structure elucidation and synthesis. J Nat Prod (2007) 1.06
Exiguamine A, an indoleamine-2,3-dioxygenase (IDO) inhibitor isolated from the marine sponge Neopetrosia exigua. J Am Chem Soc (2006) 1.05
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Regulation of mTORC1 signaling by pH. PLoS One (2011) 1.04
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Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen. Antimicrob Agents Chemother (2011) 1.00
Liphagal, a Selective inhibitor of PI3 kinase alpha isolated from the sponge akacoralliphaga: structure elucidation and biomimetic synthesis. Org Lett (2006) 0.98
Intravesical combination treatment with antisense oligonucleotides targeting heat shock protein-27 and HTI-286 as a novel strategy for high-grade bladder cancer. Mol Cancer Ther (2009) 0.98
Nahuoic acid A produced by a Streptomyces sp. isolated from a marine sediment is a selective SAM-competitive inhibitor of the histone methyltransferase SETD8. Org Lett (2012) 0.97
Caminoside A, an antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia. Org Lett (2002) 0.97
Padanamides A and B, highly modified linear tetrapeptides produced in culture by a Streptomyces sp. isolated from a marine sediment. Org Lett (2011) 0.96
Neopetrosiamides, peptides from the marine sponge Neopetrosia sp. that inhibit amoeboid invasion by human tumor cells. Org Lett (2005) 0.95
Dhilirolides A-D, meroterpenoids produced in culture by the fruit-infecting fungus Penicillium purpurogenum collected in Sri Lanka. Org Lett (2011) 0.94
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The autophagy inhibitor verteporfin moderately enhances the antitumor activity of gemcitabine in a pancreatic ductal adenocarcinoma model. J Cancer (2013) 0.93
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Dominicin, a cyclic octapeptide, and laughine, a bromopyrrole alkaloid, isolated from the Caribbean marine sponge Eurypon laughlini. J Nat Prod (2005) 0.93
Motuporamines, anti-invasion and anti-angiogenic alkaloids from the marine sponge Xestospongia exigua (Kirkpatrick): isolation, structure elucidation, analogue synthesis, and conformational analysis. J Org Chem (2002) 0.93
Effect of combined DNA repair inhibition and G2 checkpoint inhibition on cell cycle progression after DNA damage. Mol Cancer Ther (2006) 0.93
Crystal structures of protein phosphatase-1 bound to motuporin and dihydromicrocystin-LA: elucidation of the mechanism of enzyme inhibition by cyanobacterial toxins. J Mol Biol (2005) 0.92
Biomimetic synthesis of the IDO inhibitors exiguamine A and B. Nat Chem Biol (2008) 0.92
Rolloamides A and B, cytotoxic cyclic heptapeptides isolated from the Caribbean marine sponge Eurypon laughlini. J Nat Prod (2009) 0.92
Bafilomycins produced in culture by Streptomyces spp. isolated from marine habitats are potent inhibitors of autophagy. J Nat Prod (2010) 0.92
Activation of SHIP via a small molecule agonist kills multiple myeloma cells. Exp Hematol (2009) 0.92
Caminosides B-D, antimicrobial glycolipids isolated from the marine sponge Caminus sphaeroconia. J Nat Prod (2006) 0.91
Small molecule modulation of the human chromatid decatenation checkpoint. Chem Biol (2003) 0.91
Niphatenones, glycerol ethers from the sponge Niphates digitalis block androgen receptor transcriptional activity in prostate cancer cells: structure elucidation, synthesis, and biological activity. J Med Chem (2011) 0.91
Hortonones A to C, hydroazulenones from the genus Hortonia. J Nat Prod (2012) 0.90
Spirastrellolides C to G: macrolides obtained from the marine sponge Spirastrella coccinea. J Org Chem (2007) 0.90
Synthesis and antimitotic/cytotoxic activity of hemiasterlin analogues. J Nat Prod (2003) 0.89
Intravesical chemotherapy of high-grade bladder cancer with HTI-286, a synthetic analogue of the marine sponge product hemiasterlin. Clin Cancer Res (2008) 0.89
Synthesis of pelorol and analogues: activators of the inositol 5-phosphatase SHIP. Org Lett (2005) 0.89
Indoleamine 2,3-dioxygenase inhibitors from the Northeastern Pacific Marine Hydroid Garveia annulata. J Nat Prod (2006) 0.88
The tumor invasion inhibitor dihydromotuporamine C activates RHO, remodels stress fibers and focal adhesions, and stimulates sodium-proton exchange. Cancer Res (2004) 0.88
Synthetic approaches to the microtubule-stabilizing sponge alkaloid ceratamine A and desbromo analogues. J Org Chem (2009) 0.88
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Inhibition of Chk1 by the G2 DNA damage checkpoint inhibitor isogranulatimide. Mol Cancer Ther (2004) 0.86
N-carbamoylation of 2,4-diaminobutyrate reroutes the outcome in padanamide biosynthesis. Chem Biol (2013) 0.86
Effects of chemical manipulation of mitotic arrest and slippage on cancer cell survival and proliferation. Cell Cycle (2009) 0.85
Niclosamide prevents the formation of large ubiquitin-containing aggregates caused by proteasome inhibition. PLoS One (2010) 0.85
Diterpenoids from cultured Erythropodium caribaeorum. Org Lett (2002) 0.85
Latonduines A and B, new alkaloids isolated from the marine sponge Stylissa carteri: structure elucidation, synthesis, and biogenetic implications. Org Lett (2003) 0.85
Correction of F508del-CFTR trafficking by the sponge alkaloid latonduine is modulated by interaction with PARP. Chem Biol (2012) 0.85
Targeting prostate cancer with HTI-286, a synthetic analog of the marine sponge product hemiasterlin. Int J Cancer (2008) 0.84
Meroterpenoid MAPKAP (MK2) inhibitors isolated from the indonesian marine sponge Acanthodendrilla sp. J Nat Prod (2004) 0.84
Hypotensive and cardio-chronotropic constituents of Tinospora crispa and mechanisms of action on the cardiovascular system in anesthetized rats. J Ethnopharmacol (2012) 0.84
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Inhibitors of the G2 DNA damage checkpoint and their potential for cancer therapy. Prog Cell Cycle Res (2003) 0.84
Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A. J Med Chem (2008) 0.84
Multiparameter screening reveals a role for Na+ channels in cytokine-induced β-cell death. Mol Endocrinol (2014) 0.83
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Identification of novel small molecule inhibitors of centrosome clustering in cancer cells. Oncotarget (2013) 0.83