Dieder Moechars

Author PubWeight™ 23.56‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice. J Biol Chem 2005 2.03
2 Transgenic mice overexpressing glycogen synthase kinase 3beta: a putative model of hyperactivity and mania. J Neurosci 2006 2.01
3 Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis. Mol Cell Biol 2005 2.00
4 Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice. J Neurosci 2002 1.94
5 Characterization of amyloid beta peptides from brain extracts of transgenic mice overexpressing the London mutant of human amyloid precursor protein. J Neurochem 2003 1.05
6 Mammalian Navigators are microtubule plus-end tracking proteins that can reorganize the cytoskeleton to induce neurite-like extensions. Cell Motil Cytoskeleton 2009 1.03
7 Role of ghrelin in the relationship between hyperphagia and accelerated gastric emptying in diabetic mice. Gastroenterology 2008 1.03
8 Impairment of VGLUT2 but not VGLUT1 signaling reduces neuropathy-induced hypersensitivity. Eur J Pain 2009 0.96
9 IMPA1 is essential for embryonic development and lithium-like pilocarpine sensitivity. Neuropsychopharmacology 2007 0.96
10 Preclinical evaluation of 18F-JNJ41510417 as a radioligand for PET imaging of phosphodiesterase-10A in the brain. J Nucl Med 2010 0.95
11 Obestatin induction of early-response gene expression in gastrointestinal and adipose tissues and the mediatory role of G protein-coupled receptor, GPR39. Mol Endocrinol 2008 0.94
12 Synaptic dysfunction in hippocampus of transgenic mouse models of Alzheimer's disease: a multi-electrode array study. Neurobiol Dis 2011 0.89
13 Nav2 is necessary for cranial nerve development and blood pressure regulation. Neural Dev 2010 0.89
14 Lack of lithium-like behavioral and molecular effects in IMPA2 knockout mice. Neuropsychopharmacology 2006 0.85
15 Nav2 hypomorphic mutant mice are ataxic and exhibit abnormalities in cerebellar development. Dev Biol 2011 0.83
16 Modulation of group II metabotropic glutamate receptor (mGlu2) elicits common changes in rat and mice sleep-wake architecture. Eur J Pharmacol 2008 0.82
17 Decreased expression of multidrug efflux transporters in the brains of GSK-3beta transgenic mice. Brain Res 2009 0.80
18 The high-level similarity of some disparate gene expression measures. Bioinformatics 2007 0.79
19 Inactivation of the constitutively active ghrelin receptor attenuates limbic seizure activity in rodents. Neurotherapeutics 2012 0.79
20 Pharmacological profile of JNJ-27141491 [(S)-3-[3,4-difluorophenyl)-propyl]-5-isoxazol-5-yl-2-thioxo-2,3-dihydro-1H-imidazole-4-carboxyl acid methyl ester], as a noncompetitive and orally active antagonist of the human chemokine receptor CCR2. J Pharmacol Exp Ther 2008 0.78
21 In vivo evidence for ligand-specific receptor activation in the central CRF system, as measured by local cerebral glucose utilization. Peptides 2009 0.78
22 Rational design and synthesis of aminopiperazinones as β-secretase (BACE) inhibitors. Bioorg Med Chem Lett 2011 0.76
23 Demonstration of vesicular glutamate transporter-1 in corticotroph cells in the anterior pituitary of the rat. Neurochem Int 2009 0.75
24 Neuropathobiology in transgenic mice. The case of Alzheimer's disease. Methods Mol Biol 2003 0.75