Published in Neuropsychopharmacology on April 25, 2007
The Concise Guide to PHARMACOLOGY 2013/14: enzymes. Br J Pharmacol (2013) 5.57
An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons. Nat Neurosci (2010) 1.68
A safe lithium mimetic for bipolar disorder. Nat Commun (2013) 1.51
Validating GSK3 as an in vivo target of lithium action. Biochem Soc Trans (2009) 1.27
Inhibition of GSK3 by lithium, from single molecules to signaling networks. Front Mol Neurosci (2012) 1.14
Identification of male-specific amh duplication, sexually differentially expressed genes and microRNAs at early embryonic development of Nile tilapia (Oreochromis niloticus). BMC Genomics (2014) 0.98
Inositol-related gene knockouts mimic lithium's effect on mitochondrial function. Neuropsychopharmacology (2013) 0.97
Molecular actions and clinical pharmacogenetics of lithium therapy. Pharmacol Biochem Behav (2014) 0.94
Defective craniofacial development and brain function in a mouse model for depletion of intracellular inositol synthesis. J Biol Chem (2014) 0.83
Synaptic polarity depends on phosphatidylinositol signaling regulated by myo-inositol monophosphatase in Caenorhabditis elegans. Genetics (2012) 0.81
The longer U(T)R, the further you go. Nat Neurosci (2010) 0.78
IP3 accumulation and/or inositol depletion: two downstream lithium's effects that may mediate its behavioral and cellular changes. Transl Psychiatry (2016) 0.75
A homozygous loss-of-function mutation in inositol monophosphatase 1 (IMPA1) causes severe intellectual disability. Mol Psychiatry (2015) 0.75
RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors. N Engl J Med (2012) 6.93
Major depressive disorder. N Engl J Med (2008) 6.61
Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome. Hum Mol Genet (2004) 2.61
LRRK2 controls an EndoA phosphorylation cycle in synaptic endocytosis. Neuron (2012) 2.49
Neuropeptide systems as novel therapeutic targets for depression and anxiety disorders. Trends Pharmacol Sci (2003) 2.37
I/NI-calls for the exclusion of non-informative genes: a highly effective filtering tool for microarray data. Bioinformatics (2007) 2.34
Removing obstacles in neuroscience drug discovery: the future path for animal models. Neuropsychopharmacology (2008) 2.16
Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice. J Biol Chem (2005) 2.03
Transgenic mice overexpressing glycogen synthase kinase 3beta: a putative model of hyperactivity and mania. J Neurosci (2006) 2.01
Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis. Mol Cell Biol (2005) 2.00
Rapid tryptophan depletion as a treatment for acute mania: a double-blind, pilot-controlled study. Bipolar Disord (2007) 1.99
Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice. J Neurosci (2002) 1.94
A CSF and postmortem brain study of D-serine metabolic parameters in schizophrenia. Schizophr Res (2006) 1.67
Omega-3 eicosapentaenoic acid in bipolar depression: report of a small open-label study. J Clin Psychiatry (2005) 1.54
Vesicular glutamate transporter VGLUT2 expression levels control quantal size and neuropathic pain. J Neurosci (2006) 1.54
Effect of prolonged phenytoin administration on rat brain gene expression assessed by DNA microarrays. Exp Biol Med (Maywood) (2010) 1.44
p53-independent regulation of p21Waf1/Cip1 expression and senescence by Chk2. Mol Cancer Res (2005) 1.39
Curcumin as an add-on to antidepressive treatment: a randomized, double-blind, placebo-controlled, pilot clinical study. Clin Neuropharmacol (2013) 1.39
Double-Blind, Randomized, Placebo-Controlled Trial of Metoclopramide for Hypersalivation Associated With Clozapine. J Clin Psychopharmacol (2016) 1.39
In situ detection of starvation-induced autophagy. J Histochem Cytochem (2005) 1.38
Valproate decreases inositol biosynthesis. Biol Psychiatry (2004) 1.33
Conserved interneuron-specific ErbB4 expression in frontal cortex of rodents, monkeys, and humans: implications for schizophrenia. Biol Psychiatry (2011) 1.22
Detection of autophagy in tissue by standard immunohistochemistry: possibilities and limitations. Autophagy (2006) 1.18
NMDA receptors, cognition and schizophrenia--testing the validity of the NMDA receptor hypofunction hypothesis. Neuropharmacology (2011) 1.16
Effects of transgenic overproduction of CRH on anxiety-like behaviour. Eur J Neurosci (2002) 1.15
Severe Coxsackie virus B infection in preterm newborns treated with pleconaril. Eur J Pediatr (2002) 1.14
GSK-3 and the neurodevelopmental hypothesis of schizophrenia. Eur Neuropsychopharmacol (2002) 1.13
Blocking melanin-concentrating hormone MCH1 receptor affects rat sleep-wake architecture. Eur J Pharmacol (2007) 1.13
Glycogen synthase kinase-3beta heterozygote knockout mice as a model of findings in postmortem schizophrenia brain or as a model of behaviors mimicking lithium action: negative results. Behav Pharmacol (2008) 1.12
Altered gastrointestinal and metabolic function in the GPR39-obestatin receptor-knockout mouse. Gastroenterology (2006) 1.12
JNJ-26481585, a novel "second-generation" oral histone deacetylase inhibitor, shows broad-spectrum preclinical antitumoral activity. Clin Cancer Res (2009) 1.09
In vivo electroporation of the central nervous system: a non-viral approach for targeted gene delivery. Prog Neurobiol (2010) 1.05
Characterization of amyloid beta peptides from brain extracts of transgenic mice overexpressing the London mutant of human amyloid precursor protein. J Neurochem (2003) 1.05
Psychotropic drugs affect Ser9-phosphorylated GSK-3 beta protein levels in rodent frontal cortex. Int J Neuropsychopharmacol (2005) 1.05
Human 1-D-myo-inositol-3-phosphate synthase is functional in yeast. J Biol Chem (2004) 1.04
Anxiolytic- and antidepressant-like profile of a new CRF1 receptor antagonist, R278995/CRA0450. Eur J Pharmacol (2004) 1.04
Asymptomatic small fiber neuropathy in diabetes mellitus: investigations with intraepidermal nerve fiber density, quantitative sensory testing and laser-evoked potentials. J Neurol (2011) 1.03
Mammalian Navigators are microtubule plus-end tracking proteins that can reorganize the cytoskeleton to induce neurite-like extensions. Cell Motil Cytoskeleton (2009) 1.03
Role of ghrelin in the relationship between hyperphagia and accelerated gastric emptying in diabetic mice. Gastroenterology (2008) 1.03
Knockout mice in understanding the mechanism of action of lithium. Biochem Soc Trans (2009) 1.02
Search for a common mechanism of mood stabilizers. Biochem Pharmacol (2003) 1.02
Vesicular glutamate transporter VGLUT1 has a role in hippocampal long-term potentiation and spatial reversal learning. Cereb Cortex (2009) 1.01
Inhibition of histone deacetylases by chlamydocin induces apoptosis and proteasome-mediated degradation of survivin. J Pharmacol Exp Ther (2003) 1.01
Homozygote inositol transporter knockout mice show a lithium-like phenotype. Bipolar Disord (2008) 1.00
Nicotine improves working memory span capacity in rats following sub-chronic ketamine exposure. Neuropsychopharmacology (2011) 0.98
The chromatin-binding protein HMGN1 regulates the expression of methyl CpG-binding protein 2 (MECP2) and affects the behavior of mice. J Biol Chem (2011) 0.98
Dihydrothiazolopyridone derivatives as a novel family of positive allosteric modulators of the metabotropic glutamate 5 (mGlu5) receptor. J Med Chem (2013) 0.97
Impairment of VGLUT2 but not VGLUT1 signaling reduces neuropathy-induced hypersensitivity. Eur J Pain (2009) 0.96
Exposure to high- and low-light conditions in an open-field test of anxiety increases c-Fos expression in specific subdivisions of the rat basolateral amygdaloid complex. Brain Res Bull (2006) 0.95
Metabotropic glutamate receptors: their therapeutic potential in anxiety. Curr Top Behav Neurosci (2010) 0.95
Activity-dependent neuroprotective protein (ADNP) expression level is correlated with the expression of the sister protein ADNP2: deregulation in schizophrenia. Eur Neuropsychopharmacol (2010) 0.95
LRRK2 functions in synaptic vesicle endocytosis through a kinase-dependent mechanism. J Cell Sci (2015) 0.95
Preclinical evaluation of 18F-JNJ41510417 as a radioligand for PET imaging of phosphodiesterase-10A in the brain. J Nucl Med (2010) 0.95
Homocysteine-reducing strategies improve symptoms in chronic schizophrenic patients with hyperhomocysteinemia. Biol Psychiatry (2006) 0.94
Western blot analysis of a limited number of cells: a valuable adjunct to proteome analysis of paraffin wax-embedded, alcohol-fixed tissue after laser capture microdissection. J Pathol (2004) 0.94
Overexpression of corticotropin-releasing hormone in transgenic mice and chronic stress-like autonomic and physiological alterations. Eur J Neurosci (2002) 0.94
Optimization of an ether series of mGlu5 positive allosteric modulators: molecular determinants of MPEP-site interaction crossover. Bioorg Med Chem Lett (2012) 0.94
Effect of valproate derivatives on human brain myo-inositol-1-phosphate (MIP) synthase activity and amphetamine-induced rearing. Pharmacol Rep (2007) 0.94
Obestatin induction of early-response gene expression in gastrointestinal and adipose tissues and the mediatory role of G protein-coupled receptor, GPR39. Mol Endocrinol (2008) 0.94
Impaired heart rate variability in euthymic bipolar patients. Bipolar Disord (2003) 0.93
Metabotropic glutamate mGlu1 receptor stimulation and blockade: therapeutic opportunities in psychiatric illness. Eur J Pharmacol (2010) 0.93
Tetrahydronaphthyridine and dihydronaphthyridinone ethers as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu₅). J Med Chem (2014) 0.92
The utility of patient specific induced pluripotent stem cells for the modelling of Autistic Spectrum Disorders. Psychopharmacology (Berl) (2013) 0.91
Chronic corticosterone manipulations in mice affect brain cell proliferation rates, but only partly affect BDNF protein levels. Neurosci Lett (2005) 0.91
Alteration of frizzled expression in renal cell carcinoma. Tumour Biol (2004) 0.90
Cholinergic blockade impairs performance in operant DNMTP in two inbred strains of mice. Pharmacol Biochem Behav (2002) 0.90
The biology of tryptophan depletion and mood disorders. Isr J Psychiatry Relat Sci (2010) 0.90
A selective, non-peptide CRF receptor 1 antagonist prevents sodium lactate-induced acute panic-like responses. Int J Neuropsychopharmacol (2010) 0.90
Lymphoblast and brain expression of AHI1 and the novel primate-specific gene, C6orf217, in schizophrenia and bipolar disorder. Schizophr Res (2010) 0.90
Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53. Brain Res Dev Brain Res (2004) 0.89
Synaptic dysfunction in hippocampus of transgenic mouse models of Alzheimer's disease: a multi-electrode array study. Neurobiol Dis (2011) 0.89
Nav2 is necessary for cranial nerve development and blood pressure regulation. Neural Dev (2010) 0.89
GSK-3 parameters in postmortem frontal cortex and hippocampus of schizophrenic patients. Schizophr Res (2004) 0.88
GSK-3 parameters in lymphocytes of schizophrenic patients. Psychiatry Res (2002) 0.87
The time course of CO2 laser-evoked responses and of skin nerve fibre markers after topical capsaicin in human volunteers. Clin Neurophysiol (2010) 0.87
Health provider determinants of nonattendance in pediatric otolaryngology patients. Laryngoscope (2005) 0.87
Lithium-pilocarpine seizures as a model for lithium action in mania. Neurosci Biobehav Rev (2007) 0.86
Myo-inositol-1-phosphate (MIP) synthase: a possible new target for antibipolar drugs. Bipolar Disord (2002) 0.86
Lithium preferentially inhibits adenylyl cyclase V and VII isoforms. Int J Neuropsychopharmacol (2008) 0.86
Individual differences and evidence-based psychopharmacology. BMC Med (2012) 0.86
Assessing behavioural and cognitive domains of autism spectrum disorders in rodents: current status and future perspectives. Psychopharmacology (Berl) (2013) 0.86
The effect of lithium on expression of genes for inositol biosynthetic enzymes in mouse hippocampus; a comparison with the yeast model. Brain Res Mol Brain Res (2003) 0.86
Gene expression profiles highlight adaptive brain mechanisms in corticotropin releasing factor overexpressing mice. Brain Res Mol Brain Res (2004) 0.85
Lack of lithium-like behavioral and molecular effects in IMPA2 knockout mice. Neuropsychopharmacology (2006) 0.85