|
1
|
Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER.
|
Cell
|
2002
|
5.70
|
|
2
|
SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast.
|
Cell
|
2005
|
2.81
|
|
3
|
Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been.
|
Genes Dev
|
2009
|
2.37
|
|
4
|
Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes.
|
Cell Metab
|
2007
|
2.30
|
|
5
|
Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast.
|
Mol Cell Biol
|
2006
|
2.11
|
|
6
|
Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans.
|
Mol Microbiol
|
2007
|
1.93
|
|
7
|
Hierarchical modularity and the evolution of genetic interactomes across species.
|
Mol Cell
|
2012
|
1.88
|
|
8
|
Expanding roles for SREBP in metabolism.
|
Cell Metab
|
2012
|
1.76
|
|
9
|
Oxygen-regulated degradation of fission yeast SREBP by Ofd1, a prolyl hydroxylase family member.
|
EMBO J
|
2008
|
1.61
|
|
10
|
Sterol regulatory element binding proteins in fungi: hypoxic transcription factors linked to pathogenesis.
|
Eukaryot Cell
|
2010
|
1.49
|
|
11
|
4-Methyl sterols regulate fission yeast SREBP-Scap under low oxygen and cell stress.
|
J Biol Chem
|
2007
|
1.22
|
|
12
|
Regulation of HMG-CoA reductase in mammals and yeast.
|
Prog Lipid Res
|
2011
|
1.22
|
|
13
|
SREBP controls oxygen-dependent mobilization of retrotransposons in fission yeast.
|
PLoS Genet
|
2007
|
1.21
|
|
14
|
Oxygen-dependent binding of Nro1 to the prolyl hydroxylase Ofd1 regulates SREBP degradation in yeast.
|
EMBO J
|
2009
|
1.20
|
|
15
|
Cobalt chloride, a hypoxia-mimicking agent, targets sterol synthesis in the pathogenic fungus Cryptococcus neoformans.
|
Mol Microbiol
|
2007
|
1.17
|
|
16
|
Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.
|
Mol Cell
|
2011
|
1.11
|
|
17
|
Cryptococcus neoformans Site-2 protease is required for virulence and survival in the presence of azole drugs.
|
Mol Microbiol
|
2009
|
1.11
|
|
18
|
Insig regulates HMG-CoA reductase by controlling enzyme phosphorylation in fission yeast.
|
Cell Metab
|
2008
|
1.09
|
|
19
|
Yeast sterol regulatory element-binding protein (SREBP) cleavage requires Cdc48 and Dsc5, a ubiquitin regulatory X domain-containing subunit of the Golgi Dsc E3 ligase.
|
J Biol Chem
|
2011
|
1.07
|
|
20
|
Degradation of sterol regulatory element-binding protein precursor requires the endoplasmic reticulum-associated degradation components Ubc7 and Hrd1 in fission yeast.
|
J Biol Chem
|
2009
|
1.07
|
|
21
|
Regulation of the Sre1 hypoxic transcription factor by oxygen-dependent control of DNA binding.
|
Mol Cell
|
2011
|
0.98
|
|
22
|
Sterol regulatory element-binding protein (SREBP) cleavage regulates Golgi-to-endoplasmic reticulum recycling of SREBP cleavage-activating protein (SCAP).
|
J Biol Chem
|
2014
|
0.97
|
|
23
|
Ergosterol regulates sterol regulatory element binding protein (SREBP) cleavage in fission yeast.
|
J Biol Chem
|
2010
|
0.96
|
|
24
|
Identification of twenty-three mutations in fission yeast Scap that constitutively activate SREBP.
|
J Lipid Res
|
2008
|
0.95
|
|
25
|
Oxygen-dependent, alternative promoter controls translation of tco1+ in fission yeast.
|
Nucleic Acids Res
|
2008
|
0.90
|
|
26
|
Subunit architecture of the Golgi Dsc E3 ligase required for sterol regulatory element-binding protein (SREBP) cleavage in fission yeast.
|
J Biol Chem
|
2013
|
0.86
|
|
27
|
The hypoxic regulator of sterol synthesis nro1 is a nuclear import adaptor.
|
Structure
|
2011
|
0.83
|
|
28
|
Regulation of SREBP during hypoxia requires Ofd1-mediated control of both DNA binding and degradation.
|
Mol Biol Cell
|
2012
|
0.82
|
|
29
|
Casein kinase 1 regulates sterol regulatory element-binding protein (SREBP) to control sterol homeostasis.
|
J Biol Chem
|
2013
|
0.79
|
|
30
|
Regulation of lipid metabolism: a tale of two yeasts.
|
Curr Opin Cell Biol
|
2012
|
0.78
|
|
31
|
Structural requirements for sterol regulatory element-binding protein (SREBP) cleavage in fission yeast.
|
J Biol Chem
|
2013
|
0.78
|
|
32
|
Glucose controls phosphoregulation of hydroxymethylglutaryl coenzyme A reductase through the protein phosphatase 2A-related phosphatase protein, Ppe1, and Insig in fission yeast.
|
J Biol Chem
|
2011
|
0.78
|
|
33
|
Identifying a static nonlinear structure in a biological system using noisy, sparse data.
|
J Theor Biol
|
2012
|
0.77
|