Published in Curr Opin Cell Biol on April 26, 2007
TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres. Mol Cell (2009) 2.60
Mutations in the pre-replication complex cause Meier-Gorlin syndrome. Nat Genet (2011) 1.74
Orc1 controls centriole and centrosome copy number in human cells. Science (2009) 1.65
Mechanisms and pathways of growth failure in primordial dwarfism. Genes Dev (2011) 1.56
The origin recognition complex protein family. Genome Biol (2009) 1.40
A WD-repeat protein stabilizes ORC binding to chromatin. Mol Cell (2010) 1.38
Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization. Proc Natl Acad Sci U S A (2010) 1.38
RNA-dependent recruitment of the origin recognition complex. EMBO J (2008) 1.37
Replication timing and epigenetic reprogramming of gene expression: a two-way relationship? Nat Rev Genet (2009) 1.22
Specific function of phosphoinositide 3-kinase beta in the control of DNA replication. Proc Natl Acad Sci U S A (2009) 1.17
Alternative functions of core cell cycle regulators in neuronal migration, neuronal maturation, and synaptic plasticity. Neuron (2009) 1.16
Regulation of DNA replication during development. Development (2012) 1.13
In vitro nuclear interactome of the HIV-1 Tat protein. Retrovirology (2009) 1.13
Chromatin organization of gammaherpesvirus latent genomes. Biochim Biophys Acta (2009) 1.12
The genetics of symptom-based phenotypes: toward a molecular classification of schizophrenia. Schizophr Bull (2008) 1.11
Structural analysis of human Orc6 protein reveals a homology with transcription factor TFIIB. Proc Natl Acad Sci U S A (2011) 1.10
Arabidopsis ORC1 is a PHD-containing H3K4me3 effector that regulates transcription. Proc Natl Acad Sci U S A (2009) 1.07
The origin recognition complex: a biochemical and structural view. Subcell Biochem (2012) 1.05
Genome-wide analysis reveals extensive functional interaction between DNA replication initiation and transcription in the genome of Trypanosoma brucei. Cell Rep (2012) 1.01
Bacterial origin recognition complexes direct assembly of higher-order DnaA oligomeric structures. Proc Natl Acad Sci U S A (2009) 1.01
ABAP1 is a novel plant Armadillo BTB protein involved in DNA replication and transcription. EMBO J (2008) 0.99
Trypanosoma brucei Orc1 is essential for nuclear DNA replication and affects both VSG silencing and VSG switching. Mol Microbiol (2012) 0.98
The dynamics of eukaryotic replication initiation: origin specificity, licensing, and firing at the single-molecule level. Mol Cell (2015) 0.95
Drosophila Orc6 facilitates GTPase activity and filament formation of the septin complex. Mol Biol Cell (2008) 0.94
Dynamic interactions of high Cdt1 and geminin levels regulate S phase in early Xenopus embryos. Development (2011) 0.92
Identification of ORC1/CDC6-interacting factors in Trypanosoma brucei reveals critical features of origin recognition complex architecture. PLoS One (2012) 0.92
The preRC protein ORCA organizes heterochromatin by assembling histone H3 lysine 9 methyltransferases on chromatin. Elife (2015) 0.90
Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control. Cell Microbiol (2013) 0.89
Origin recognition complex (ORC) mediates histone 3 lysine 4 methylation through cooperation with Spp1 in Saccharomyces cerevisiae. J Biol Chem (2008) 0.88
How the cell cycle impacts chromatin architecture and influences cell fate. Front Genet (2015) 0.87
Functional analysis of an Orc6 mutant in Drosophila. Proc Natl Acad Sci U S A (2009) 0.87
Phylogenetic conservation and homology modeling help reveal a novel domain within the budding yeast heterochromatin protein Sir1. Mol Cell Biol (2008) 0.84
Positive roles of SAS2 in DNA replication and transcriptional silencing in yeast. Nucleic Acids Res (2008) 0.83
Assembly of the human origin recognition complex occurs through independent nuclear localization of its components. J Biol Chem (2011) 0.83
The role of N-terminus of Plasmodium falciparum ORC1 in telomeric localization and var gene silencing. Nucleic Acids Res (2012) 0.82
A journey through the microscopic ages of DNA replication. Protoplasma (2016) 0.81
LINEs of evidence: noncanonical DNA replication as an epigenetic determinant. Biol Direct (2013) 0.80
Functional insight into the role of Orc6 in septin complex filament formation in Drosophila. Mol Biol Cell (2014) 0.79
ORC4 surrounds extruded chromatin in female meiosis. J Cell Biochem (2015) 0.79
Trypanosoma cruzi DNA replication includes the sequential recruitment of pre-replication and replication machineries close to nuclear periphery. Nucleus (2011) 0.79
The origin recognition complex in human diseases. Biosci Rep (2013) 0.79
Interactions of a replication initiator with histone H1-like proteins remodel the condensed mitochondrial genome. J Biol Chem (2011) 0.78
Regulating DNA replication in plants. Cold Spring Harb Perspect Biol (2012) 0.78
Ustilago maydis transcript features identified through full-length cDNA analysis. Mol Genet Genomics (2011) 0.78
Opposing roles for DNA replication initiator proteins ORC1 and CDC6 in control of Cyclin E gene transcription. Elife (2016) 0.77
Human DNA helicase B interacts with the replication initiation protein Cdc45 and facilitates Cdc45 binding onto chromatin. Exp Cell Res (2015) 0.76
Orc5 induces large-scale chromatin decondensation in a GCN5-dependent manner. J Cell Sci (2015) 0.75
Higher Order Oligomerization of the Licensing ORC4 Protein Is Required for Polar Body Extrusion in Murine Meiosis. J Cell Biochem (2017) 0.75
The plant cell cycle: Pre-Replication complex formation and controls. Genet Mol Biol (2017) 0.75
Maintenance of stable heterochromatin domains by dynamic HP1 binding. Science (2003) 4.74
Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types. Genome Res (2010) 4.67
Global reorganization of replication domains during embryonic stem cell differentiation. PLoS Biol (2008) 4.50
An encyclopedia of mouse DNA elements (Mouse ENCODE). Genome Biol (2012) 4.15
Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis. Genome Res (2009) 3.36
Defining functional DNA elements in the human genome. Proc Natl Acad Sci U S A (2014) 3.35
Actin up in the nucleus. Nat Rev Mol Cell Biol (2004) 2.13
Heterochromatin, HP1 and methylation at lysine 9 of histone H3 in animals. Chromosoma (2002) 2.03
Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation. Mol Cell (2012) 2.02
Heterochromatin and tri-methylated lysine 20 of histone H4 in animals. J Cell Sci (2004) 1.98
G9a selectively represses a class of late-replicating genes at the nuclear periphery. Proc Natl Acad Sci U S A (2009) 1.91
Mouse Rif1 is a key regulator of the replication-timing programme in mammalian cells. EMBO J (2012) 1.85
Replication timing and transcriptional control: beyond cause and effect--part II. Curr Opin Genet Dev (2009) 1.84
Differential subnuclear localization and replication timing of histone H3 lysine 9 methylation states. Mol Biol Cell (2005) 1.77
Epigenomic replication: linking epigenetics to DNA replication. Bioessays (2003) 1.66
Proliferation-dependent and cell cycle regulated transcription of mouse pericentric heterochromatin. J Cell Biol (2007) 1.59
Replication timing as an epigenetic mark. Epigenetics (2009) 1.53
Differentiation-induced replication-timing changes are restricted to AT-rich/long interspersed nuclear element (LINE)-rich isochores. Proc Natl Acad Sci U S A (2004) 1.53
Mammalian nuclei become licensed for DNA replication during late telophase. J Cell Sci (2002) 1.51
ReplicationDomain: a visualization tool and comparative database for genome-wide replication timing data. BMC Bioinformatics (2008) 1.51
Genome-scale analysis of replication timing: from bench to bioinformatics. Nat Protoc (2011) 1.49
Uncoupling global and fine-tuning replication timing determinants for mouse pericentric heterochromatin. J Cell Biol (2006) 1.41
DNA replication timing. Cold Spring Harb Perspect Biol (2013) 1.38
Productive hepatitis C virus infection of stem cell-derived hepatocytes reveals a critical transition to viral permissiveness during differentiation. PLoS Pathog (2012) 1.29
Structure of a palindromic amplicon junction implicates microhomology-mediated end joining as a mechanism of sister chromatid fusion during gene amplification. Nucleic Acids Res (2004) 1.23
Replication timing: a fingerprint for cell identity and pluripotency. PLoS Comput Biol (2011) 1.21
FISH Finder: a high-throughput tool for analyzing FISH images. Bioinformatics (2011) 1.20
Chromatin-interaction compartment switch at developmentally regulated chromosomal domains reveals an unusual principle of chromatin folding. Proc Natl Acad Sci U S A (2012) 1.17
Pre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zone. Nucleic Acids Res (2010) 1.13
Abnormal developmental control of replication-timing domains in pediatric acute lymphoblastic leukemia. Genome Res (2012) 1.11
Spatial distribution and specification of mammalian replication origins during G1 phase. J Cell Biol (2003) 1.09
Spatio-temporal organization of DNA replication in murine embryonic stem, primary, and immortalized cells. J Cell Biochem (2005) 1.08
The Chinese hamster dihydrofolate reductase replication origin decision point follows activation of transcription and suppresses initiation of replication within transcription units. Mol Cell Biol (2006) 1.07
Domain-wide regulation of DNA replication timing during mammalian development. Chromosome Res (2010) 1.06
DNA replication timing is maintained genome-wide in primary human myoblasts independent of D4Z4 contraction in FSH muscular dystrophy. PLoS One (2011) 1.01
G2 phase chromatin lacks determinants of replication timing. J Cell Biol (2010) 1.01
RB reversibly inhibits DNA replication via two temporally distinct mechanisms. Mol Cell Biol (2004) 1.01
Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload. J Cell Biol (2011) 1.00
Chinese hamster ORC subunits dynamically associate with chromatin throughout the cell-cycle. Exp Cell Res (2005) 0.95
Replication labeling with halogenated thymidine analogs. Curr Protoc Cell Biol (2007) 0.95
Replication-timing boundaries facilitate cell-type and species-specific regulation of a rearranged human chromosome in mouse. Hum Mol Genet (2012) 0.92
DNA Replication Timing. Cold Spring Harb Perspect Med (2013) 0.90
Replication origins run (ultra) deep. Nat Struct Mol Biol (2012) 0.89
Observing S-phase dynamics of histone modifications with fluorescently labeled antibodies. Methods Mol Biol (2006) 0.88
Electrolytic transformation of ordinance related compounds (ORCs) in groundwater: laboratory mass balance studies. Chemosphere (2005) 0.88
The distribution of genomic variations in human iPSCs is related to replication-timing reorganization during reprogramming. Cell Rep (2014) 0.87
Overexpression of ORC subunits and increased ORC-chromatin association in transformed mammalian cells. J Cell Biochem (2005) 0.86
The replication domain model: regulating replicon firing in the context of large-scale chromosome architecture. J Mol Biol (2013) 0.86
Sensitivity of the origin decision point to specific inhibitors of cellular signaling and metabolism. Exp Cell Res (2002) 0.85
SnapShot: Replication timing. Cell (2013) 0.85
Evidence for a pre-restriction point Cdk3 activity. J Cell Biochem (2002) 0.84
Cell cycle regulated transcription of heterochromatin in mammals vs. fission yeast: functional conservation or coincidence? Cell Cycle (2008) 0.84
Developmental control of replication timing defines a new breed of chromosomal domains with a novel mechanism of chromatin unfolding. Nucleus (2012) 0.83
Microfluidic extraction and stretching of chromosomal DNA from single cell nuclei for DNA fluorescence in situ hybridization. Biomed Microdevices (2012) 0.80
Replication timing and metazoan evolution. Nat Genet (2002) 0.79
Evidence for a mammalian late-G1 phase inhibitor of replication licensing distinct from geminin or Cdk activity. Nucleus (2011) 0.77
Development of a single-cell array for large-scale DNA fluorescence in situ hybridization. Lab Chip (2013) 0.77
Nucleus and gene expression: the structure and function conundrum. Curr Opin Cell Biol (2010) 0.77
Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease. Proc Natl Acad Sci U S A (2014) 0.76
Autosomal lyonization of replication domains during early Mammalian development. Adv Exp Med Biol (2010) 0.76
Genome-wide analysis of replication timing in mammalian cells: troubleshooting problems encountered when comparing different cell types. Methods (2012) 0.75
Low-cost fabrication of centimetre-scale periodic arrays of single plasmid DNA molecules. Lab Chip (2013) 0.75