Published in Neurochem Res on May 05, 2007
Nonallele-specific silencing of mutant and wild-type huntingtin demonstrates therapeutic efficacy in Huntington's disease mice. Mol Ther (2009) 2.47
Alzheimer's disease as homeostatic responses to age-related myelin breakdown. Neurobiol Aging (2009) 2.14
Development of a robust method for generating 7.0 T multichannel phase images of the brain with application to normal volunteers and patients with neurological diseases. Neuroimage (2007) 1.88
MRI estimates of brain iron concentration in normal aging using quantitative susceptibility mapping. Neuroimage (2011) 1.87
Diffusion tensor imaging of deep gray matter brain structures: effects of age and iron concentration. Neurobiol Aging (2008) 1.81
Striatal and white matter predictors of estimated diagnosis for Huntington disease. Brain Res Bull (2010) 1.79
MRI estimates of brain iron concentration in normal aging: comparison of field-dependent (FDRI) and phase (SWI) methods. Neuroimage (2009) 1.51
Cerebral cortex structure in prodromal Huntington disease. Neurobiol Dis (2010) 1.17
A delicate balance: Iron metabolism and diseases of the brain. Front Aging Neurosci (2013) 1.11
Integrated Laplacian-based phase unwrapping and background phase removal for quantitative susceptibility mapping. NMR Biomed (2013) 1.11
Peroxisome-proliferator-activated receptor gamma coactivator 1 α contributes to dysmyelination in experimental models of Huntington's disease. J Neurosci (2011) 1.09
Structural MRI detects progressive regional brain atrophy and neuroprotective effects in N171-82Q Huntington's disease mouse model. Neuroimage (2011) 1.05
The emerging role of iron dyshomeostasis in the mitochondrial decay of aging. Mech Ageing Dev (2010) 1.00
Contrasting gray and white matter changes in preclinical Huntington disease: an MRI study. Neurology (2010) 1.00
Alterations in brain transition metals in Huntington disease: an evolving and intricate story. Arch Neurol (2012) 0.99
Brain, blood, and iron: perspectives on the roles of erythrocytes and iron in neurodegeneration. Neurobiol Dis (2012) 0.99
Time-efficient, high-resolution, whole brain three-dimensional macromolecular proton fraction mapping. Magn Reson Med (2015) 0.99
Effects of aging and calorie restriction on white matter in rhesus macaques. Neurobiol Aging (2010) 0.98
Gender and iron genes may modify associations between brain iron and memory in healthy aging. Neuropsychopharmacology (2011) 0.96
CSF T-Tau/Aβ42 predicts white matter microstructure in healthy adults at risk for Alzheimer's disease. PLoS One (2012) 0.95
MRI T2 Hypointensities in basal ganglia of premanifest Huntington's disease. PLoS Curr (2010) 0.93
PGC-1α, mitochondrial dysfunction, and Huntington's disease. Free Radic Biol Med (2013) 0.92
Combining atlas-based parcellation of regional brain data acquired across scanners at 1.5 T and 3.0 T field strengths. Neuroimage (2012) 0.92
Diffusion Tensor Imaging in Preclinical Huntington's Disease. Brain Imaging Behav (2009) 0.90
Correlations of behavioral deficits with brain pathology assessed through longitudinal MRI and histopathology in the R6/2 mouse model of HD. PLoS One (2013) 0.89
Multi-modal neuroimaging in premanifest and early Huntington's disease: 18 month longitudinal data from the IMAGE-HD study. PLoS One (2013) 0.89
Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease. Hum Mol Genet (2015) 0.87
Tractography of the corpus callosum in Huntington's disease. PLoS One (2013) 0.86
Mutant huntingtin downregulates myelin regulatory factor-mediated myelin gene expression and affects mature oligodendrocytes. Neuron (2015) 0.85
Metal and complementary molecular bioimaging in Alzheimer's disease. Front Aging Neurosci (2014) 0.84
Deep white matter in Huntington's disease. PLoS One (2014) 0.83
Quantitative susceptibility mapping by inversion of a perturbation field model: correlation with brain iron in normal aging. IEEE Trans Med Imaging (2014) 0.82
Comparison of histological techniques to visualize iron in paraffin-embedded brain tissue of patients with Alzheimer's disease. J Histochem Cytochem (2013) 0.82
Oligodendroglia and neurotrophic factors in neurodegeneration. Neurosci Bull (2013) 0.81
Focal dystonia and the Sensory-Motor Integrative Loop for Enacting (SMILE). Front Hum Neurosci (2014) 0.80
Regulation of quinolinic acid neosynthesis in mouse, rat and human brain by iron and iron chelators in vitro. J Neural Transm (Vienna) (2011) 0.80
Changes in the striatal proteome of YAC128Q mice exhibit gene-environment interactions between mutant huntingtin and manganese. J Proteome Res (2012) 0.80
Role of iron in neurodegenerative diseases. J Neural Transm (Vienna) (2016) 0.79
Striatal development involves a switch in gene expression networks, followed by a myelination event: implications for neuropsychiatric disease. Synapse (2012) 0.78
Iron is a specific cofactor for distinct oxidation- and aggregation-dependent Aβ toxicity mechanisms in a Drosophila model. Dis Model Mech (2015) 0.78
Quantitative Susceptibility Mapping Suggests Altered Brain Iron in Premanifest Huntington Disease. AJNR Am J Neuroradiol (2015) 0.78
Striatal oligodendrogliogenesis and neuroblast recruitment are increased in the R6/2 mouse model of Huntington's disease. Brain Res (2013) 0.77
Robust MR-based approaches to quantifying white matter structure and structure/function alterations in Huntington's disease. J Neurosci Methods (2015) 0.77
Selective reduction of striatal mature BDNF without induction of proBDNF in the zQ175 mouse model of Huntington's disease. Neurobiol Dis (2015) 0.77
Quantitative 7T phase imaging in premanifest Huntington disease. AJNR Am J Neuroradiol (2014) 0.77
iPSC-based drug screening for Huntington׳s disease. Brain Res (2015) 0.77
Oligodendroglia and Myelin in Neurodegenerative Diseases: More Than Just Bystanders? Mol Neurobiol (2015) 0.76
Structural and molecular myelination deficits occur prior to neuronal loss in the YAC128 and BACHD models of Huntington disease. Hum Mol Genet (2016) 0.76
Postnatal and adult consequences of loss of huntingtin during development: Implications for Huntington's disease. Neurobiol Dis (2016) 0.76
Insights into the role of iron in immature rat model of hypoxic-ischemic brain injury. Exp Ther Med (2016) 0.75
Major Superficial White Matter Abnormalities in Huntington's Disease. Front Neurosci (2016) 0.75
Correlation between relaxometry and diffusion tensor imaging in the globus pallidus of Huntington's disease patients. PLoS One (2015) 0.75
Voluntary saccade inhibition deficits correlate with extended white-matter cortico-basal atrophy in Huntington's disease. Neuroimage Clin (2017) 0.75
Expression of RNAs Coding for Metal Transporters in Blood of Patients with Huntington's Disease. Neurochem Res (2015) 0.75
Monitoring Huntington's disease progression through preclinical and early stages. Neurodegener Dis Manag (2012) 0.75
T1ρ imaging in premanifest Huntington disease reveals changes associated with disease progression. Mov Disord (2015) 0.75
Inversion recovery ultrashort echo time magnetic resonance imaging: A method for simultaneous direct detection of myelin and high signal demonstration of iron deposition in the brain - A feasibility study. Magn Reson Imaging (2016) 0.75
Cardiovascular function in multi-ethnic study of atherosclerosis: normal values by age, sex, and ethnicity. AJR Am J Roentgenol (2006) 6.13
Caution regarding the use of pilot studies to guide power calculations for study proposals. Arch Gen Psychiatry (2006) 5.30
The MATRICS Consensus Cognitive Battery, part 2: co-norming and standardization. Am J Psychiatry (2008) 4.02
Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophrenia. Arch Gen Psychiatry (2007) 2.91
Brief cognitive-behavioral therapy effects on post-treatment suicide attempts in a military sample: results of a randomized clinical trial with 2-year follow-up. Am J Psychiatry (2015) 2.80
The neurocognitive effects of low-dose haloperidol: a two-year comparison with risperidone. Biol Psychiatry (2002) 2.70
Risperidone nonadherence and return of positive symptoms in the early course of schizophrenia. Am J Psychiatry (2011) 2.47
Effects of antenatal depression and antidepressant treatment on gestational age at birth and risk of preterm birth. Am J Psychiatry (2007) 2.47
A placebo-controlled evaluation of adjunctive modafinil in the treatment of bipolar depression. Am J Psychiatry (2007) 2.45
Genome-wide gene-environment study identifies glutamate receptor gene GRIN2A as a Parkinson's disease modifier gene via interaction with coffee. PLoS Genet (2011) 2.28
Clinical features and molecular genetics of autosomal recessive cerebellar ataxias. Lancet Neurol (2007) 2.24
ACCF/ACR/AHA/NASCI/SCMR 2010 expert consensus document on cardiovascular magnetic resonance: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents. J Am Coll Cardiol (2010) 2.23
Heterogeneous age-related breakdown of white matter structural integrity: implications for cortical "disconnection" in aging and Alzheimer's disease. Neurobiol Aging (2004) 2.23
Family-focused treatment versus individual treatment for bipolar disorder: results of a randomized clinical trial. J Consult Clin Psychol (2003) 2.20
Correlates of treatment-emergent mania associated with antidepressant treatment in bipolar depression. Am J Psychiatry (2008) 2.17
ACCF/ACR/AHA/NASCI/SCMR 2010 expert consensus document on cardiovascular magnetic resonance: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents. Circulation (2010) 2.14
Consistency of Brief Psychiatric Rating Scale factor structure across a broad spectrum of schizophrenia patients. Psychopathology (2007) 2.01
White matter structural integrity in healthy aging adults and patients with Alzheimer disease: a magnetic resonance imaging study. Arch Neurol (2003) 1.93
Lifespan trajectory of myelin integrity and maximum motor speed. Neurobiol Aging (2008) 1.92
Is emotion processing a predictor of functional outcome in schizophrenia? Schizophr Bull (2003) 1.89
The Consortium on the Genetics of Endophenotypes in Schizophrenia: model recruitment, assessment, and endophenotyping methods for a multisite collaboration. Schizophr Bull (2006) 1.88
Brain ferritin iron may influence age- and gender-related risks of neurodegeneration. Neurobiol Aging (2006) 1.87
Increased amygdala activation during mania: a functional magnetic resonance imaging study. Am J Psychiatry (2005) 1.84
Conceptualizing impulsivity and risk taking in bipolar disorder: importance of history of alcohol abuse. Bipolar Disord (2009) 1.82
Left ventricular papillary muscle mass: relationship to left ventricular mass and volumes by magnetic resonance imaging. J Comput Assist Tomogr (2006) 1.77
The use of individually tailored environmental supports to improve medication adherence and outcomes in schizophrenia. Schizophr Bull (2007) 1.72
Neurocognitive function in clinically stable men with bipolar I disorder or schizophrenia and normal control subjects. Biol Psychiatry (2004) 1.72
Meta-analysis of 123I-MIBG cardiac scintigraphy for the diagnosis of Lewy body-related disorders. Mov Disord (2011) 1.67
Schizophrenia as one extreme of a sexually selected fitness indicator. Schizophr Res (2004) 1.61
A multidose study of haloperidol decanoate in the maintenance treatment of schizophrenia. Am J Psychiatry (2002) 1.55
Coronary artery fistulas: CT findings. Radiographics (2009) 1.54
Second-generation antipsychotic exposure and metabolic-related disorders in patients with schizophrenia: an observational pharmacoepidemiology study from 1988 to 2002. J Clin Psychopharmacol (2007) 1.54
High-spatial-resolution lower extremity MR angiography at 3.0 T: contrast agent dose comparison study. Radiology (2008) 1.50
Clinical feature profile of spinocerebellar ataxia type 1-8 predicts genetically defined subtypes. Mov Disord (2005) 1.49
Impedance monitoring during catheter ablation of atrial fibrillation. Heart Rhythm (2005) 1.49
Abandoned pacemaker leads are a potential risk for patients undergoing MRI. Pacing Clin Electrophysiol (2011) 1.45
The Cardiac Atlas Project--an imaging database for computational modeling and statistical atlases of the heart. Bioinformatics (2011) 1.44
Blunted activation in orbitofrontal cortex during mania: a functional magnetic resonance imaging study. Biol Psychiatry (2005) 1.44
An approach to the patient with late-onset cerebellar ataxia. Nat Clin Pract Neurol (2006) 1.40
Neurocognitive predictors of work outcome in recent-onset schizophrenia. Schizophr Bull (2011) 1.38
Novel mutations in the senataxin DNA/RNA helicase domain in ataxia with oculomotor apraxia 2. Neurology (2006) 1.37
Neuropsychiatric symptoms are associated with progression from mild cognitive impairment to Alzheimer's disease. Dement Geriatr Cogn Disord (2007) 1.35
Increased anterior cingulate/medial prefrontal cortical glutamate and creatine in bipolar depression. Neuropsychopharmacology (2007) 1.33
α-Synuclein genetic variants predict faster motor symptom progression in idiopathic Parkinson disease. PLoS One (2012) 1.33
Social cognition [corrected] and neurocognition: effects of risperidone, olanzapine, and haloperidol. Am J Psychiatry (2007) 1.32
TrueFISP: assessment of accuracy for measurement of left ventricular mass in an animal model. J Magn Reson Imaging (2002) 1.31
Neuropsychological deficits among patients with late-onset minor and major depression. Arch Clin Neuropsychol (2003) 1.30
Measuring the rate of progression in Friedreich ataxia: implications for clinical trial design. Mov Disord (2010) 1.29
A videotape intervention to enhance the informed consent process for medical and psychiatric treatment research. Am J Psychiatry (2005) 1.29
Computer-assisted self-assessment in persons with severe mental illness. J Clin Psychiatry (2004) 1.28
Do the siblings of schizophrenia patients demonstrate affect perception deficits? Schizophr Res (2004) 1.27
Measurement of brain metabolites in patients with type 2 diabetes and major depression using proton magnetic resonance spectroscopy. Neuropsychopharmacology (2006) 1.27
Bipolar pharmacotherapy and suicidal behavior. Part I: Lithium, divalproex and carbamazepine. J Affect Disord (2007) 1.26
A patient with Huntington's disease and long-surviving fetal neural transplants that developed mass lesions. Acta Neuropathol (2008) 1.25
Neuropsychiatric predictors of return to work in HIV/AIDS. J Int Neuropsychol Soc (2007) 1.25
Successful multi-site measurement of antisaccade performance deficits in schizophrenia. Schizophr Res (2006) 1.25
Regional brain changes in bipolar I depression: a functional magnetic resonance imaging study. Bipolar Disord (2008) 1.25
Subsyndromal depressive symptoms are associated with functional impairment in patients with bipolar disorder: results of a large, multisite study. J Clin Psychiatry (2006) 1.24
Brain ferritin iron as a risk factor for age at onset in neurodegenerative diseases. Ann N Y Acad Sci (2004) 1.23
Improving informed consent: the medium is not the message. IRB (2004) 1.23
Gray matter prefrontal changes in type 2 diabetes detected using MRI. J Magn Reson Imaging (2008) 1.22
Apolipoprotein E genotype and age-related myelin breakdown in healthy individuals: implications for cognitive decline and dementia. Arch Gen Psychiatry (2006) 1.22
Subsyndromal depression is associated with functional impairment in patients with bipolar disorder. J Clin Psychiatry (2002) 1.22
Brain maturation may be arrested in chronic cocaine addicts. Biol Psychiatry (2002) 1.20
Heart failure: evaluation of cardiopulmonary transit times with time-resolved MR angiography. Radiology (2003) 1.20
Time-lapse mapping of cortical changes in schizophrenia with different treatments. Cereb Cortex (2008) 1.20
MR Imaging of the heart with cine true fast imaging with steady-state precession: influence of spatial and temporal resolutions on left ventricular functional parameters. Radiology (2002) 1.18
Left ventricular mass: manual and automatic segmentation of true FISP and FLASH cine MR images in dogs and pigs. Radiology (2003) 1.18
Traumatic brain injury, paraquat exposure, and their relationship to Parkinson disease. Neurology (2012) 1.17
Mixed hypomania in 908 patients with bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar Treatment Network: a sex-specific phenomenon. Arch Gen Psychiatry (2005) 1.16
Multimodal magnetic resonance imaging assessment of white matter aging trajectories over the lifespan of healthy individuals. Biol Psychiatry (2012) 1.15
Rationale and design for the Defibrillators to Reduce Risk by Magnetic Resonance Imaging Evaluation (DETERMINE) trial. J Cardiovasc Electrophysiol (2009) 1.15
Conducting empirical research on informed consent: challenges and questions. IRB (2004) 1.14
Common data elements for clinical research in Friedreich's ataxia. Mov Disord (2012) 1.14
Multislice first-pass myocardial perfusion imaging: Comparison of saturation recovery (SR)-TrueFISP-two-dimensional (2D) and SR-TurboFLASH-2D pulse sequences. J Magn Reson Imaging (2004) 1.14
Pacemaker lead tip heating in abandoned and pacemaker-attached leads at 1.5 Tesla MRI. J Magn Reson Imaging (2011) 1.14
Depressive symptoms in mild cognitive impairment predict greater atrophy in Alzheimer's disease-related regions. Biol Psychiatry (2012) 1.13
Disease management in Latinos with schizophrenia: a family-assisted, skills training approach. Schizophr Bull (2003) 1.13
Double-blind, randomized, placebo-controlled trials of ethyl-eicosapentanoate in the treatment of bipolar depression and rapid cycling bipolar disorder. Biol Psychiatry (2006) 1.13
In vivo evidence of differential impact of typical and atypical antipsychotics on intracortical myelin in adults with schizophrenia. Schizophr Res (2009) 1.12
Dysregulated brain development in adult men with schizophrenia: a magnetic resonance imaging study. Biol Psychiatry (2003) 1.12
Multi-site studies of acoustic startle and prepulse inhibition in humans: initial experience and methodological considerations based on studies by the Consortium on the Genetics of Schizophrenia. Schizophr Res (2007) 1.11
Mutations in rare ataxia genes are uncommon causes of sporadic cerebellar ataxia. Mov Disord (2012) 1.10
Human brain myelination and amyloid beta deposition in Alzheimer's disease. Alzheimers Dement (2007) 1.10