Miduturu Srinivas

Author PubWeight™ 22.84‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Potent block of Cx36 and Cx50 gap junction channels by mefloquine. Proc Natl Acad Sci U S A 2004 2.61
2 Differentially altered Ca2+ regulation and Ca2+ permeability in Cx26 hemichannels formed by the A40V and G45E mutations that cause keratitis ichthyosis deafness syndrome. J Gen Physiol 2010 1.45
3 Loop gating of connexin hemichannels involves movement of pore-lining residues in the first extracellular loop domain. J Biol Chem 2008 1.36
4 New possible roles for aquaporin-4 in astrocytes: cell cytoskeleton and functional relationship with connexin43. FASEB J 2005 1.28
5 Divalent cations regulate connexin hemichannels by modulating intrinsic voltage-dependent gating. J Gen Physiol 2008 1.26
6 Prospects for rational development of pharmacological gap junction channel blockers. Curr Drug Targets 2002 1.22
7 Block of specific gap junction channel subtypes by 2-aminoethoxydiphenyl borate (2-APB). J Pharmacol Exp Ther 2006 1.20
8 Optimal lens epithelial cell proliferation is dependent on the connexin isoform providing gap junctional coupling. Invest Ophthalmol Vis Sci 2007 1.19
9 Functional characterization of a naturally occurring Cx50 truncation. Invest Ophthalmol Vis Sci 2006 1.12
10 Virtual cloning, functional expression, and gating analysis of human connexin31.9. Am J Physiol Cell Physiol 2002 1.10
11 Transfection of mammalian cells with connexins and measurement of voltage sensitivity of their gap junctions. Nat Protoc 2006 1.04
12 Interaction between Connexin50 and mitogen-activated protein kinase signaling in lens homeostasis. Mol Biol Cell 2009 1.03
13 The D50N mutation and syndromic deafness: altered Cx26 hemichannel properties caused by effects on the pore and intersubunit interactions. J Gen Physiol 2013 1.01
14 Connexin43 mutation causes heterogeneous gap junction loss and sudden infant death. Circulation 2011 1.00
15 Functional effects of Cx50 mutations associated with congenital cataracts. Am J Physiol Cell Physiol 2013 0.96
16 The N-terminal half of the connexin protein contains the core elements of the pore and voltage gates. J Membr Biol 2012 0.93
17 Molecular cloning and functional expression of zfCx52.6: a novel connexin with hemichannel-forming properties expressed in horizontal cells of the zebrafish retina. J Biol Chem 2003 0.91
18 Mechanism of inhibition of connexin channels by the quinine derivative N-benzylquininium. J Gen Physiol 2012 0.85
19 Mefloquine effects on the lens suggest cooperative gating of gap junction channels. J Membr Biol 2006 0.80
20 Triarylmethanes, a new class of cx50 inhibitors. Front Pharmacol 2012 0.76