| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline.
|
J Clin Endocrinol Metab
|
2010
|
7.15
|
|
2
|
Effects of Testosterone Treatment in Older Men.
|
N Engl J Med
|
2016
|
6.66
|
|
3
|
Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer.
|
Cancer Res
|
2007
|
5.97
|
|
4
|
Testosterone therapy in adult men with androgen deficiency syndromes: an endocrine society clinical practice guideline.
|
J Clin Endocrinol Metab
|
2006
|
5.58
|
|
5
|
Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: induction of steroidogenesis and androgen receptor splice variants.
|
Clin Cancer Res
|
2011
|
4.65
|
|
6
|
Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice.
|
Nat Genet
|
2003
|
3.78
|
|
7
|
Exogenous testosterone (T) alone or with finasteride increases physical performance, grip strength, and lean body mass in older men with low serum T.
|
J Clin Endocrinol Metab
|
2004
|
3.02
|
|
8
|
Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors.
|
Cancer Res
|
2011
|
2.81
|
|
9
|
Prevalence and incidence of androgen deficiency in middle-aged and older men: estimates from the Massachusetts Male Aging Study.
|
J Clin Endocrinol Metab
|
2004
|
2.73
|
|
10
|
Persistent intraprostatic androgen concentrations after medical castration in healthy men.
|
J Clin Endocrinol Metab
|
2006
|
2.57
|
|
11
|
Exogenous testosterone or testosterone with finasteride increases bone mineral density in older men with low serum testosterone.
|
J Clin Endocrinol Metab
|
2004
|
2.39
|
|
12
|
Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone mineral density in hypogonadal men.
|
J Clin Endocrinol Metab
|
2004
|
2.35
|
|
13
|
Testosterone treatment and mortality in men with low testosterone levels.
|
J Clin Endocrinol Metab
|
2012
|
2.29
|
|
14
|
Low serum testosterone and mortality in male veterans.
|
Arch Intern Med
|
2006
|
2.28
|
|
15
|
Low testosterone associated with obesity and the metabolic syndrome contributes to sexual dysfunction and cardiovascular disease risk in men with type 2 diabetes.
|
Diabetes Care
|
2011
|
1.60
|
|
16
|
The effect of 5alpha-reductase inhibition with dutasteride and finasteride on semen parameters and serum hormones in healthy men.
|
J Clin Endocrinol Metab
|
2007
|
1.53
|
|
17
|
Association of bioavailable, free, and total testosterone with insulin resistance: influence of sex hormone-binding globulin and body fat.
|
Diabetes Care
|
2004
|
1.47
|
|
18
|
The Testosterone Trials: Seven coordinated trials of testosterone treatment in elderly men.
|
Clin Trials
|
2014
|
1.46
|
|
19
|
Intratesticular androgens and spermatogenesis during severe gonadotropin suppression induced by male hormonal contraceptive treatment.
|
J Androl
|
2007
|
1.45
|
|
20
|
Serum insulin-like factor 3 is highly correlated with intratesticular testosterone in normal men with acute, experimental gonadotropin deficiency stimulated with low-dose human chorionic gonadotropin: a randomized, controlled trial.
|
Fertil Steril
|
2012
|
1.44
|
|
21
|
Serum testosterone and estradiol in sudden infant death.
|
J Pediatr
|
2005
|
1.40
|
|
22
|
The effect of diurnal variation on clinical measurement of serum testosterone and other sex hormone levels in men.
|
J Clin Endocrinol Metab
|
2008
|
1.37
|
|
23
|
Increased incidence of diagnosed depressive illness in hypogonadal older men.
|
Arch Gen Psychiatry
|
2004
|
1.30
|
|
24
|
Intraindividual variation in levels of serum testosterone and other reproductive and adrenal hormones in men.
|
Clin Endocrinol (Oxf)
|
2007
|
1.30
|
|
25
|
Incidence, natural history, and risk factors for biliary sludge and stones during pregnancy.
|
Hepatology
|
2005
|
1.24
|
|
26
|
Testosterone supplementation therapy for older men: potential benefits and risks.
|
J Am Geriatr Soc
|
2003
|
1.24
|
|
27
|
Testosterone administration suppresses adiponectin levels in men.
|
J Androl
|
2004
|
1.24
|
|
28
|
Dihydrotestosterone and the prostate: the scientific rationale for 5alpha-reductase inhibitors in the treatment of benign prostatic hyperplasia.
|
J Urol
|
2004
|
1.22
|
|
29
|
Effect of medical castration on CD4+ CD25+ T cells, CD8+ T cell IFN-gamma expression, and NK cells: a physiological role for testosterone and/or its metabolites.
|
Am J Physiol Endocrinol Metab
|
2005
|
1.21
|
|
30
|
Cortisol levels and measures of body composition in middle-aged and older men.
|
Clin Endocrinol (Oxf)
|
2007
|
1.20
|
|
31
|
Low-dose human chorionic gonadotropin maintains intratesticular testosterone in normal men with testosterone-induced gonadotropin suppression.
|
J Clin Endocrinol Metab
|
2005
|
1.19
|
|
32
|
Serum testosterone assays--accuracy matters.
|
J Clin Endocrinol Metab
|
2004
|
1.19
|
|
33
|
A randomized, double-blind, placebo-controlled study of testosterone treatment in hypogonadal older men with subthreshold depression (dysthymia or minor depression).
|
J Clin Psychiatry
|
2009
|
1.18
|
|
34
|
Targeted androgen pathway suppression in localized prostate cancer: a pilot study.
|
J Clin Oncol
|
2013
|
1.14
|
|
35
|
Testosterone gel combined with depomedroxyprogesterone acetate is an effective male hormonal contraceptive regimen and is not enhanced by the addition of a GnRH antagonist.
|
J Clin Endocrinol Metab
|
2006
|
1.05
|
|
36
|
Low testosterone levels predict incident depressive illness in older men: effects of age and medical morbidity.
|
J Clin Psychiatry
|
2005
|
1.04
|
|
37
|
Dihydrotestosterone administration does not increase intraprostatic androgen concentrations or alter prostate androgen action in healthy men: a randomized-controlled trial.
|
J Clin Endocrinol Metab
|
2010
|
1.04
|
|
38
|
Low testosterone is associated with decreased function and increased mortality risk: a preliminary study of men in a geriatric rehabilitation unit.
|
J Am Geriatr Soc
|
2004
|
1.02
|
|
39
|
Intratesticular testosterone concentrations comparable with serum levels are not sufficient to maintain normal sperm production in men receiving a hormonal contraceptive regimen.
|
J Androl
|
2004
|
1.00
|
|
40
|
Incidence and severity of sexual adverse experiences in finasteride and placebo-treated men with benign prostatic hyperplasia.
|
Urology
|
2003
|
0.98
|
|
41
|
New testosterone buccal system (Striant) delivers physiological testosterone levels: pharmacokinetics study in hypogonadal men.
|
J Clin Endocrinol Metab
|
2004
|
0.97
|
|
42
|
Association of sex hormones with sexual function, vitality, and physical function of symptomatic older men with low testosterone levels at baseline in the testosterone trials.
|
J Clin Endocrinol Metab
|
2014
|
0.92
|
|
43
|
Acceptability of a combination testosterone gel and depomedroxyprogesterone acetate male contraceptive regimen.
|
Contraception
|
2007
|
0.90
|
|
44
|
Tissue selectivity of the anabolic steroid, 19-nor-4-androstenediol-3beta,17beta-diol in male Sprague Dawley rats: selective stimulation of muscle mass and bone mineral density relative to prostate mass.
|
Endocrinology
|
2007
|
0.88
|
|
45
|
Preoperative supraphysiological testosterone in older men undergoing knee replacement surgery.
|
J Am Geriatr Soc
|
2002
|
0.88
|
|
46
|
Testosterone replacement in hypogonadal men alters the HDL proteome but not HDL cholesterol efflux capacity.
|
J Lipid Res
|
2012
|
0.87
|
|
47
|
Increased hypothalamic melanin concentrating hormone gene expression during energy restriction involves a melanocortin-independent, estrogen-sensitive mechanism.
|
Peptides
|
2004
|
0.87
|
|
48
|
Long-term effects of dimethandrolone 17β-undecanoate and 11β-methyl-19-nortestosterone 17β-dodecylcarbonate on body composition, bone mineral density, serum gonadotropins, and androgenic/anabolic activity in castrated male rats.
|
J Androl
|
2010
|
0.86
|
|
49
|
Testosterone (T)-induced changes in arcuate nucleus cocaine-amphetamine-regulated transcript and NPY mRNA are attenuated in old compared to young male brown Norway rats: contribution of T to age-related changes in cocaine-amphetamine-regulated transcript and NPY gene expression.
|
Endocrinology
|
2002
|
0.86
|
|
50
|
Performance of total testosterone measurement to predict free testosterone for the biochemical evaluation of male hypogonadism.
|
J Urol
|
2012
|
0.86
|
|
51
|
Serum 17-hydroxyprogesterone strongly correlates with intratesticular testosterone in gonadotropin-suppressed normal men receiving various dosages of human chorionic gonadotropin.
|
Fertil Steril
|
2007
|
0.85
|
|
52
|
Relationship between serum gonadotropins and spermatogenic suppression in men undergoing steroidal contraceptive treatment.
|
J Clin Endocrinol Metab
|
2004
|
0.84
|
|
53
|
Dutasteride reduces prostate size and prostate specific antigen in older hypogonadal men with benign prostatic hyperplasia undergoing testosterone replacement therapy.
|
J Urol
|
2011
|
0.83
|
|
54
|
Intramuscular testosterone enanthate plus very low dosage oral levonorgestrel suppresses spermatogenesis without causing weight gain in normal young men: a randomized clinical trial.
|
J Androl
|
2005
|
0.83
|
|
55
|
The effect of 5alpha-reductase inhibition with dutasteride and finasteride on bone mineral density, serum lipoproteins, hemoglobin, prostate specific antigen and sexual function in healthy young men.
|
J Urol
|
2008
|
0.83
|
|
56
|
Testosterone, dihydrotestosterone, and incident cardiovascular disease and mortality in the cardiovascular health study.
|
J Clin Endocrinol Metab
|
2014
|
0.83
|
|
57
|
Mechanism of action of bolandiol (19-nortestosterone-3beta,17beta-diol), a unique anabolic steroid with androgenic, estrogenic, and progestational activities.
|
J Steroid Biochem Mol Biol
|
2009
|
0.82
|
|
58
|
Blunted hypothalamic neuropeptide gene expression in response to fasting, but preservation of feeding responses to AgRP in aging male Brown Norway rats.
|
Am J Physiol Regul Integr Comp Physiol
|
2004
|
0.82
|
|
59
|
Lack of seasonal variation in serum sex hormone levels in middle-aged to older men in the Boston area.
|
J Clin Endocrinol Metab
|
2007
|
0.81
|
|
60
|
Masculine vitality: pros and cons of testosterone in treating the andropause.
|
J Gerontol A Biol Sci Med Sci
|
2004
|
0.81
|
|
61
|
Testosterone and dihydrotestosterone and incident ischaemic stroke in men in the Cardiovascular Health Study.
|
Clin Endocrinol (Oxf)
|
2014
|
0.81
|
|
62
|
Impact of male hormonal contraception on prostate androgens and androgen action in healthy men: a randomized, controlled trial.
|
J Clin Endocrinol Metab
|
2012
|
0.80
|
|
63
|
Elevated end-of-treatment serum INSL3 is associated with failure to completely suppress spermatogenesis in men receiving male hormonal contraception.
|
J Androl
|
2007
|
0.80
|
|
64
|
Neonatal 6-hydroxydopamine administration to mice is fatal.
|
Dev Neurosci
|
2002
|
0.80
|
|
65
|
Fundamental aspects of hypogonadism in the aging male.
|
Rev Urol
|
2003
|
0.79
|
|
66
|
The male contraceptive regimen of testosterone and levonorgestrel significantly increases lean mass in healthy young men in 4 weeks, but attenuates a decrease in fat mass induced by testosterone alone.
|
J Clin Endocrinol Metab
|
2003
|
0.79
|
|
67
|
Testosterone, aging and survival: biomarker or deficiency.
|
Curr Opin Endocrinol Diabetes Obes
|
2014
|
0.78
|
|
68
|
Troglitazone treatment of aging Brown Norway rats improves food intake and weight gain after fasting without increasing hypothalamic NPY gene expression.
|
Exp Gerontol
|
2002
|
0.78
|
|
69
|
Effects of testosterone therapy in older men.
|
JAMA
|
2008
|
0.78
|
|
70
|
Oral testosterone with and without concomitant inhibition of 5α-reductase by dutasteride in hypogonadal men for 28 days.
|
J Urol
|
2010
|
0.77
|
|
71
|
DHEA and testosterone in the elderly.
|
N Engl J Med
|
2007
|
0.77
|
|
72
|
Patient information page from The Hormone Foundation. Patient guide to testosterone therapy in adult men with androgen deficiency syndromes.
|
J Clin Endocrinol Metab
|
2010
|
0.76
|
|
73
|
Suppression of hypothalamic pro-opiomelanocortin (POMC) gene expression by daily melatonin supplementation in aging rats.
|
J Pineal Res
|
2003
|
0.75
|
|
74
|
Does testosterone supplementation improve health and function in elderly men?
|
Nat Clin Pract Endocrinol Metab
|
2008
|
0.75
|
|
75
|
Testicular fine-needle aspiration for the assessment of intratesticular hormone concentrations.
|
Asian J Androl
|
2015
|
0.75
|
|
76
|
Long-term outcome studies of testosterone therapy in older hypogonadal men: waiting for Godot?
|
Nat Clin Pract Endocrinol Metab
|
2008
|
0.75
|
|
77
|
Testosterone release from a subcutaneous, biodegradable microcapsule formulation (Viatrel) in hypogonadal men.
|
J Androl
|
2002
|
0.75
|
|
78
|
Daily Melatonin Administration at Middle Age Suppresses Male Rate Visceral Fat, Plasma Leptin, and Plasma Insulin to Youthful Levels.
|
Endocrinology
|
1999
|
0.75
|
|
79
|
Doping Status of DHEA Treatment for Female Athletes with Adrenal Insufficiency.
|
Clin J Sport Med
|
2017
|
0.75
|
|
80
|
Leptin levels are appropriate for body mass index in older men who experience involuntary weight loss.
|
J Am Geriatr Soc
|
2002
|
0.75
|