The pathogenic role of IgA1 O-linked glycosylation in the pathogenesis of IgA nephropathy.

PubWeight™: 0.98‹?› | Rank: Top 15%

🔗 View Article (PMID 17498123)

Published in Nephrology (Carlton) on June 01, 2007

Authors

Jonathan Barratt1, Alice C Smith, John Feehally

Author Affiliations

1: The John Walls Renal Unit, Leicester General Hospital, and Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK. jb81@le.ac.uk

Articles citing this

Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity. J Clin Invest (2009) 2.82

IgA glycosylation and IgA immune complexes in the pathogenesis of IgA nephropathy. Semin Nephrol (2008) 1.64

The level of galactose-deficient IgA1 in the sera of patients with IgA nephropathy is associated with disease progression. Kidney Int (2012) 1.31

Immunopathogenesis of IgAN. Semin Immunopathol (2007) 1.16

Structure and biological roles of mucin-type O-glycans at the ocular surface. Ocul Surf (2010) 1.01

The IgA1 immune complex-mediated activation of the MAPK/ERK kinase pathway in mesangial cells is associated with glomerular damage in IgA nephropathy. Kidney Int (2012) 0.95

Development of IgA nephropathy-like glomerulonephritis associated with Wiskott-Aldrich syndrome protein deficiency. Clin Immunol (2011) 0.89

Elucidating heterogeneity of IgA1 hinge-region O-glycosylation by use of MALDI-TOF/TOF mass spectrometry: role of cysteine alkylation during sample processing. J Proteomics (2013) 0.80

Site-specific N-glycosylation identification of recombinant human lectin-like oxidized low density lipoprotein receptor-1 (LOX-1). Glycoconj J (2012) 0.80

Development and Application of Multidimensional HPLC Mapping Method for O-linked Oligosaccharides. Biomolecules (2011) 0.78

Glyco-engineering for the production of recombinant IgA1 with distinct mucin-type O-glycans in plants. Bioengineered (2016) 0.75

Serum galactose-deficient IgA1 levels in children with IgA nephropathy. Int J Clin Exp Med (2015) 0.75

Galectin-8 in IgA nephritis: decreased binding of IgA by galectin-8 affinity chromatography and associated increased binding in non-IgA serum glycoproteins. J Clin Immunol (2011) 0.75

Articles by these authors

The Oxford classification of IgA nephropathy: rationale, clinicopathological correlations, and classification. Kidney Int (2009) 7.45

The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility. Kidney Int (2009) 7.19

Immunosuppression for progressive membranous nephropathy: a UK randomised controlled trial. Lancet (2013) 7.03

Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy. N Engl J Med (2011) 6.34

IgA nephropathy. J Am Soc Nephrol (2005) 3.65

The Oxford IgA nephropathy clinicopathological classification is valid for children as well as adults. Kidney Int (2010) 2.14

Immune complex formation in IgA nephropathy: a case of the 'right' antibodies in the 'wrong' place at the 'wrong' time? Nephrol Dial Transplant (2009) 1.53

The impact of the OFAC regulations on the work of ISN. Kidney Int (2006) 1.42

An update on the pathogenesis and treatment of IgA nephropathy. Kidney Int (2012) 1.22

Immunopathogenesis of IgAN. Semin Immunopathol (2007) 1.16

Chronic kidney disease: Health burden of kidney disease recognized by UN. Nat Rev Nephrol (2011) 1.14

Pathogenesis of IgA nephropathy. Semin Nephrol (2004) 1.11

O-glycosylation of serum IgA1 antibodies against mucosal and systemic antigens in IgA nephropathy. J Am Soc Nephrol (2006) 1.11

Primary IgA nephropathy: new insights into pathogenesis. Semin Nephrol (2011) 1.10

O-glycosylation of serum IgD in IgA nephropathy. J Am Soc Nephrol (2006) 1.04

Distinguishing C1q nephropathy from lupus nephritis. Nephrol Dial Transplant (2004) 1.03

Human serum IgA1 is substituted with up to six O-glycans as shown by matrix assisted laser desorption ionisation time-of-flight mass spectrometry. Carbohydr Res (2004) 1.02

UK Renal Registry 12th Annual Report (December 2009): chapter 4: UK ESRD prevalent rates in 2008: national and centre-specific analyses. Nephron Clin Pract (2010) 0.98

Benefits of regular walking exercise in advanced pre-dialysis chronic kidney disease. Nephrol Dial Transplant (2011) 0.95

UK Renal Registry 11th Annual Report (December 2008): Chapter 4 ESRD prevalent rates in 2007 in the UK: national and centre-specific analyses. Nephron Clin Pract (2009) 0.93

Act now against new NHS competition regulations: an open letter to the BMA and the Academy of Medical Royal Colleges calls on them to make a joint public statement of opposition to the amended section 75 regulations. BMJ (2013) 0.91

Treatment of IgA nephropathy and Henoch-Schönlein nephritis. Nat Rev Nephrol (2013) 0.90

IgA nephropathy at two score and one. Kidney Int (2009) 0.90

UK Renal Registry 11th Annual Report (December 2008): Chapter 3 ESRD incident rates in 2007 in the UK: national and centre-specific analyses. Nephron Clin Pract (2009) 0.89

Prevalence of hypertension and diabetes and coexistence of chronic kidney disease and cardiovascular risk in the population of the republic of moldova. Int J Hypertens (2012) 0.89

New insights into the pathogenesis of IgA nephropathy. Pathogenesis of IgA nephropathy. Springer Semin Immunopathol (2003) 0.88

Exercise for children with chronic kidney disease and end-stage renal disease. Pediatr Nephrol (2011) 0.87

UK Renal Registry 12th Annual Report (December 2009): chapter 3: UK ESRD incident rates in 2008: national and centre-specific analyses. Nephron Clin Pract (2010) 0.86

The International Society of Nephrology: what does "philanthropic" mean for members? Kidney Int (2009) 0.86

Glycoform composition profiling of O-glycopeptides derived from human serum IgA1 by matrix-assisted laser desorption ionization-time of flight-mass spectrometry. Anal Biochem (2004) 0.86

Lack of awareness of kidney complications despite familiarity with diabetes: a multi-ethnic qualitative study. J Ren Care (2011) 0.82

Immunoglobulin A multiple myeloma presenting with Henoch-Schönlein purpura associated with reduced sialylation of IgA1. Br J Haematol (2003) 0.82

The value of urine screening in a young adult population. Fam Pract (2004) 0.81

T-cell homing receptor expression in IgA nephropathy. Nephrol Dial Transplant (2007) 0.81

The Third World Kidney Day: looking back and thinking forward. Clin J Am Soc Nephrol (2008) 0.80

A multi-centre qualitative study exploring the experiences of UK South Asian and white diabetic patients referred for renal care. BMC Nephrol (2012) 0.78

Tonsillectomy in a European Cohort of 1,147 Patients with IgA Nephropathy. Nephron (2015) 0.78

Physiological benefits of exercise in pre-dialysis chronic kidney disease. Nephrology (Carlton) (2014) 0.78

The Impact of Exercising During Haemodialysis on Blood Pressure, Markers of Cardiac Injury and Systemic Inflammation - Preliminary Results of a Pilot Study. Kidney Blood Press Res (2015) 0.78

Inflammatory factors and exercise in chronic kidney disease. Int J Endocrinol (2013) 0.77

Effect of caffeine ingestion on lymphocyte counts and subset activation in vivo following strenuous cycling. Eur J Appl Physiol (2004) 0.77

Combined walking exercise and alkali therapy in patients with CKD4-5 regulates intramuscular free amino acid pools and ubiquitin E3 ligase expression. Eur J Appl Physiol (2013) 0.77

Raising awareness of chronic kidney disease among South Asians and primary care: the ABLE project. J Ren Care (2008) 0.77

In memoriam: Oliver M. Wrong. Kidney Int (2012) 0.77

A call to action on World Kidney Day, 8 March 2007. Kidney Int (2007) 0.76

Lymphocyte responses to influenza and tetanus toxoid in vitro following intensive exercise and carbohydrate ingestion on consecutive days. J Appl Physiol (1985) (2005) 0.76

Is sialylation of IgA the agent provocateur of IgA nephropathy? Nephrol Dial Transplant (2008) 0.76

A spoonful of sugar helps the proteinuria go down? Nephrol Dial Transplant (2007) 0.76

Inhibitors directed towards caspase-1 and -3 are less effective than pan caspase inhibition in preventing renal proximal tubular cell apoptosis. Nephron Exp Nephrol (2004) 0.76

Abnormal IgD and IgA1 O-glycosylation in hyperimmunoglobulinaemia D and periodic fever syndrome. Clin Exp Med (2009) 0.75

Is progression of IgA nephropathy conditioned by genes regulating atherosclerotic damage? Nephrol Dial Transplant (2009) 0.75

The third World Kidney Day: looking back and thinking forward. Nephrol Dial Transplant (2008) 0.75

An update on the treatment of IgA nephropathy. Curr Opin Nephrol Hypertens (2017) 0.75

A call to action on World Kidney Day, 8 March 2007. Nephrology (Carlton) (2007) 0.75

The third World Kidney Day: looking back and thinking forward. J Nephrol (2008) 0.75

The Effects of Exercise and Sport in Solid Organ Transplant Recipients: A Review. Am J Phys Med Rehabil (2016) 0.75

The International Society of Nephrology (ISN). Roles & challenges in Africa and other resource-limited communities. Clin Nephrol (2016) 0.75

The third World Kidney Day: Looking back and thinking forward. Kidney Int (2008) 0.75

The third World Kidney Day: looking back and thinking forward. Nephron Clin Pract (2008) 0.75

ERA-EDTA Immunonephrology working group. Nephrol Dial Transplant (2010) 0.75

Japan: crisis and recovery. Kidney Int (2011) 0.75

The third World Kidney Day: looking back and thinking forward. Transplantation (2008) 0.75

The Third World Kidney Day: looking back and thinking forward. Nephrology (Carlton) (2008) 0.75

The Third World Kidney Day: looking back and thinking forward. Am J Kidney Dis (2008) 0.75

The third World Kidney Day: looking back and thinking forward. Nat Clin Pract Nephrol (2008) 0.75

World Kidney Day 2011: protect your kidneys, save your heart. Rev Invest Clin (2011) 0.75

Variation in IGHMBP2 is not associated with IgA nephropathy in independent studies of UK Caucasian and Chinese Han patients. Nephrol Dial Transplant (2009) 0.75

David N.S. Kerr (1927-2014). Nephron Clin Pract (2014) 0.75

The third World Kidney Day: looking back and thinking forward. Pediatr Nephrol (2007) 0.75

Mutant mice provide new insight into the role of (mis-)glycation in IgA nephropathy and other glomerular diseases. Nephrol Dial Transplant (2007) 0.75