Published in J Biol Chem on May 14, 2007
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Aberrant corticosteroid metabolism in tumor cells enables GR takeover in enzalutamide resistant prostate cancer. Elife (2017) 1.43
Substrate-specific mediators of ER associated degradation (ERAD). Curr Opin Cell Biol (2009) 1.40
An endoplasmic reticulum (ER) membrane complex composed of SPFH1 and SPFH2 mediates the ER-associated degradation of inositol 1,4,5-trisphosphate receptors. J Biol Chem (2009) 1.26
Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. J Biol Chem (2011) 1.17
A nullimorphic ERLIN2 mutation defines a complicated hereditary spastic paraplegia locus (SPG18). Neurogenetics (2011) 1.15
Role of the ubiquitin system in regulating ion transport. Pflugers Arch (2010) 1.12
The Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage. J Biol Chem (2013) 1.05
Quantitative proteomic analyses of human cytomegalovirus-induced restructuring of endoplasmic reticulum-mitochondrial contacts at late times of infection. Mol Cell Proteomics (2011) 1.02
RNF170 protein, an endoplasmic reticulum membrane ubiquitin ligase, mediates inositol 1,4,5-trisphosphate receptor ubiquitination and degradation. J Biol Chem (2011) 1.02
When worlds collide: IP(3) receptors and the ERAD pathway. Cell Calcium (2009) 1.00
Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system. Mol Biol Cell (2012) 0.95
Distinct regions within the erlins are required for oligomerization and association with high molecular weight complexes. J Biol Chem (2009) 0.91
SPFH1 and SPFH2 mediate the ubiquitination and degradation of inositol 1,4,5-trisphosphate receptors in muscarinic receptor-expressing HeLa cells. Biochim Biophys Acta (2009) 0.89
Activation of Ca(2+) -activated Cl(-) channel ANO1 by localized Ca(2+) signals. J Physiol (2014) 0.84
Identification of replication-competent HSV-1 Cgal+ strain signaling targets in human hepatoma cells by functional organelle proteomics. Mol Cell Proteomics (2008) 0.84
ERLIN2 promotes breast cancer cell survival by modulating endoplasmic reticulum stress pathways. BMC Cancer (2012) 0.83
Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis. J Cell Biol (2013) 0.83
Superresolution imaging of viral protein trafficking. Med Microbiol Immunol (2015) 0.82
Endoplasmic reticulum factor ERLIN2 regulates cytosolic lipid content in cancer cells. Biochem J (2012) 0.82
Quantitative Proteomics and Lipidomics Analysis of Endoplasmic Reticulum of Macrophage Infected with Mycobacterium tuberculosis. Int J Proteomics (2015) 0.82
Inositol 1,4,5-trisphosphate receptors and their protein partners as signalling hubs. J Physiol (2016) 0.81
RNF185 is a novel E3 ligase of endoplasmic reticulum-associated degradation (ERAD) that targets cystic fibrosis transmembrane conductance regulator (CFTR). J Biol Chem (2013) 0.81
The Stability and Expression Level of Bok Are Governed by Binding to Inositol 1,4,5-Trisphosphate Receptors. J Biol Chem (2016) 0.77
Isolation of Endoplasmic Reticulum, Mitochondria, and Mitochondria-Associated Membrane and Detergent Resistant Membrane Fractions from Transfected Cells and from Human Cytomegalovirus-Infected Primary Fibroblasts. Curr Protoc Cell Biol (2015) 0.77
A novel ER-microtubule-binding protein, ERLIN2, stabilizes Cyclin B1 and regulates cell cycle progression. Cell Discov (2015) 0.77
Proteomic changes of the porcine small intestine in response to chronic heat stress. J Mol Endocrinol (2015) 0.76
The Sel1L-Hrd1 Endoplasmic Reticulum-Associated Degradation Complex Manages a Key Checkpoint in B Cell Development. Cell Rep (2016) 0.76
A Point Mutation in the Ubiquitin Ligase RNF170 That Causes Autosomal Dominant Sensory Ataxia Destabilizes the Protein and Impairs Inositol 1,4,5-Trisphosphate Receptor-mediated Ca2+ Signaling. J Biol Chem (2015) 0.76
The critical role of membralin in postnatal motor neuron survival and disease. Elife (2015) 0.75
Membrane Protein Quantity Control at the Endoplasmic Reticulum. J Membr Biol (2016) 0.75
Characterization of the C. elegans erlin homologue. BMC Cell Biol (2012) 0.75
Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible. Nat Genet (2006) 5.29
Aqua-[N-phenyl-2-(quinolin-8-yl-oxy)acetamide]dinitratozinc(II). Acta Crystallogr Sect E Struct Rep Online (2010) 4.92
Optical negative refraction in bulk metamaterials of nanowires. Science (2008) 3.28
Mammalian dispersal at the Paleocene/Eocene boundary. Science (2002) 2.90
Plasmon-induced transparency in metamaterials. Phys Rev Lett (2008) 2.88
cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes. Nature (2003) 2.16
PathCase: pathways database system. Bioinformatics (2008) 2.10
N-(4-Chloro-phen-yl)-2-(8-quinol-yloxy)acetamide monohydrate. Acta Crystallogr Sect E Struct Rep Online (2010) 2.04
Photonic spin Hall effect at metasurfaces. Science (2013) 2.04
miR-192 Regulates dihydrofolate reductase and cellular proliferation through the p53-microRNA circuit. Clin Cancer Res (2008) 1.87
Epac and phospholipase Cepsilon regulate Ca2+ release in the heart by activation of protein kinase Cepsilon and calcium-calmodulin kinase II. J Biol Chem (2008) 1.85
Epac-mediated activation of phospholipase C(epsilon) plays a critical role in beta-adrenergic receptor-dependent enhancement of Ca2+ mobilization in cardiac myocytes. J Biol Chem (2006) 1.82
Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells. Mol Cancer (2010) 1.77
The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK. Nat Chem Biol (2012) 1.75
Modulation of murine embryonic stem cell-derived CD41+c-kit+ hematopoietic progenitors by ectopic expression of Cdx genes. Blood (2008) 1.71
Enhance the optical absorptivity of nanocrystalline TiO2 film with high molar extinction coefficient ruthenium sensitizers for high performance dye-sensitized solar cells. J Am Chem Soc (2008) 1.68
Flying plasmonic lens in the near field for high-speed nanolithography. Nat Nanotechnol (2008) 1.65
A Middle Jurassic 'sphenosuchian' from China and the origin of the crocodylian skull. Nature (2004) 1.65
Neurotoxicity and gene-expressed profile in brain-injured mice caused by exposure to titanium dioxide nanoparticles. J Biomed Mater Res A (2013) 1.52
Role of cardiac myosin binding protein C in sustaining left ventricular systolic stiffening. Circ Res (2004) 1.52
All optical interface for parallel, remote, and spatiotemporal control of neuronal activity. Nano Lett (2007) 1.49
Association between the 5-HT1A receptor gene polymorphism (rs6295) and antidepressants: a meta-analysis. Int Clin Psychopharmacol (2012) 1.42
Phospholipase C epsilon modulates beta-adrenergic receptor-dependent cardiac contraction and inhibits cardiac hypertrophy. Circ Res (2005) 1.41
MiR-24 tumor suppressor activity is regulated independent of p53 and through a target site polymorphism. PLoS One (2009) 1.40
Substrate-specific mediators of ER associated degradation (ERAD). Curr Opin Cell Biol (2009) 1.40
(E,E)-3,3'-Dimethyl-1,1'-diphenyl-4,4'-{[3-aza-pentane-1,5-diylbis(aza-nedi-yl)]bis-(phenyl-methyl-idyne)}di-1H-pyrazol-5(4H)-one. Acta Crystallogr Sect E Struct Rep Online (2010) 1.39
Model test of anchoring effect on zonal disintegration in deep surrounding rock masses. ScientificWorldJournal (2013) 1.38
Ethyl 5-formyl-3,4-dimethyl-1H-pyrrole-2-carboxyl-ate. Acta Crystallogr Sect E Struct Rep Online (2009) 1.37
Environmental performance rating and disclosure: China's Green Watch program. J Environ Manage (2004) 1.35
Differential cross-bridge kinetics of FHC myosin mutations R403Q and R453C in heterozygous mouse myocardium. Am J Physiol Heart Circ Physiol (2004) 1.33
Maskless plasmonic lithography at 22 nm resolution. Sci Rep (2011) 1.31
Prospero-related homeobox (Prox1) is a corepressor of human liver receptor homolog-1 and suppresses the transcription of the cholesterol 7-alpha-hydroxylase gene. Mol Endocrinol (2004) 1.29
Two-state model of acto-myosin attachment-detachment predicts C-process of sinusoidal analysis. Biophys J (2007) 1.29
Characterization of the 3a protein of SARS-associated coronavirus in infected vero E6 cells and SARS patients. J Mol Biol (2004) 1.26
An endoplasmic reticulum (ER) membrane complex composed of SPFH1 and SPFH2 mediates the ER-associated degradation of inositol 1,4,5-trisphosphate receptors. J Biol Chem (2009) 1.26
Phenotypic subpopulations of metastatic colon cancer stem cells: genomic analysis. Cancer Genomics Proteomics (2009) 1.26
Phospholipase Cepsilon is a nexus for Rho and Rap-mediated G protein-coupled receptor-induced astrocyte proliferation. Proc Natl Acad Sci U S A (2007) 1.24
Synovial autoreactive T cells in rheumatoid arthritis resist IDO-mediated inhibition. J Immunol (2006) 1.19
Effect of cardiac myosin binding protein-C on mechanoenergetics in mouse myocardium. Circ Res (2004) 1.19
The effects of nocturnal life on endocrine circadian patterns in healthy adults. Life Sci (2003) 1.17
Involvement of phosphatidylinositol 3-kinase, but not RalGDS, in TC21/R-Ras2-mediated transformation. J Biol Chem (2002) 1.16
Effects of cardiac myosin isoform variation on myofilament function and crossbridge kinetics in transgenic rabbits. Circ Heart Fail (2009) 1.16
Expression of Sox2 and Oct4 and their clinical significance in human non-small-cell lung cancer. Int J Mol Sci (2012) 1.15
G-protein-coupled receptor agonists activate endogenous phospholipase Cepsilon and phospholipase Cbeta3 in a temporally distinct manner. J Biol Chem (2005) 1.14
Upregulated miR-29b promotes neuronal cell death by inhibiting Bcl2L2 after ischemic brain injury. Exp Brain Res (2011) 1.14
Involvement of the p97-Ufd1-Npl4 complex in the regulated endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors. J Biol Chem (2005) 1.13
The type III inositol 1,4,5-trisphosphate receptor is phosphorylated by cAMP-dependent protein kinase at three sites. Biochem J (2005) 1.13
Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac-selective cyclic AMP analog in rat INS-1 cells: studies with 8-pCPT-2'-O-Me-cAMP-AM. J Biol Chem (2009) 1.13
Roles for cardiac MyBP-C in maintaining myofilament lattice rigidity and prolonging myosin cross-bridge lifetime. Biophys J (2011) 1.11
Bcl-2 suppresses Ca2+ release through inositol 1,4,5-trisphosphate receptors and inhibits Ca2+ uptake by mitochondria without affecting ER calcium store content. Cell Calcium (2008) 1.11
Analysis of point mutation in site 1896 of HBV precore and its detection in the tissues and serum of HCC patients. World J Gastroenterol (2000) 1.11
Overexpression of CDC25B and LAMC2 mRNA and protein in esophageal squamous cell carcinomas and premalignant lesions in subjects from a high-risk population in China. Cancer Epidemiol Biomarkers Prev (2008) 1.11
PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM in human islets of Langerhans. Am J Physiol Endocrinol Metab (2009) 1.11
Potent in vitro and in vivo anticancer activities of des-methyl, des-amino pateamine A, a synthetic analogue of marine natural product pateamine A. Mol Cancer Ther (2009) 1.10
A preliminary study of the dysregulation of the resting networks in first-episode medication-naive adolescent depression. Neurosci Lett (2011) 1.10
Effects of barley intake on glucose tolerance, lipid metabolism, and bowel function in women. Nutrition (2003) 1.10
Bortezomib rapidly suppresses ubiquitin thiolesterification to ubiquitin-conjugating enzymes and inhibits ubiquitination of histones and type I inositol 1,4,5-trisphosphate receptor. Mol Cancer Ther (2004) 1.09
Circulating microRNA-218 was reduced in cervical cancer and correlated with tumor invasion. J Cancer Res Clin Oncol (2012) 1.09
Genetic variants in DNA repair pathway genes and risk of esophageal squamous cell carcinoma and gastric adenocarcinoma in a Chinese population. Carcinogenesis (2013) 1.08
Reaction diffusion modeling of calcium dynamics with realistic ER geometry. Biophys J (2006) 1.08
Epac2-dependent mobilization of intracellular Ca²+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ε knockout mice. J Physiol (2010) 1.07
Inositol 1,4,5-trisphosphate receptor ubiquitination is mediated by mammalian Ubc7, a component of the endoplasmic reticulum-associated degradation pathway, and is inhibited by chelation of intracellular Zn2+. J Biol Chem (2003) 1.06
Exposure to 1800 MHz radiofrequency radiation induces oxidative damage to mitochondrial DNA in primary cultured neurons. Brain Res (2009) 1.06
Glycolytic inhibition alters anaplastic thyroid carcinoma tumor metabolism and improves response to conventional chemotherapy and radiation. Mol Cancer Ther (2012) 1.06
Applying various algorithms for species distribution modelling. Integr Zool (2013) 1.05
The Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage. J Biol Chem (2013) 1.05
Phospholipase C epsilon scaffolds to muscle-specific A kinase anchoring protein (mAKAPbeta) and integrates multiple hypertrophic stimuli in cardiac myocytes. J Biol Chem (2011) 1.05
A unique pharmacophore for activation of the nuclear orphan receptor Nur77 in vivo and in vitro. Cancer Res (2010) 1.04
Myofilament mechanical performance is enhanced by R403Q myosin in mouse myocardium independent of sex. Am J Physiol Heart Circ Physiol (2008) 1.03
Gastrokine 1 induces senescence through p16/Rb pathway activation in gastric cancer cells. Gut (2011) 1.02
RNF170 protein, an endoplasmic reticulum membrane ubiquitin ligase, mediates inositol 1,4,5-trisphosphate receptor ubiquitination and degradation. J Biol Chem (2011) 1.02
Error-related negativity abnormalities in generalized anxiety disorder and obsessive-compulsive disorder. Prog Neuropsychopharmacol Biol Psychiatry (2010) 1.02
New-generation taxoid SB-T-1214 inhibits stem cell-related gene expression in 3D cancer spheroids induced by purified colon tumor-initiating cells. Mol Cancer (2010) 1.01
Development of glutamatergic synaptic transmission in binaural auditory neurons. J Neurophysiol (2010) 1.01
A sensitive and specific IgM-ELISA for the serological diagnosis of human leptospirosis using a rLipL32/1-LipL21-OmpL1/2 fusion protein. Biomed Environ Sci (2011) 1.00
When worlds collide: IP(3) receptors and the ERAD pathway. Cell Calcium (2009) 1.00
The contribution of serine residues 1588 and 1755 to phosphorylation of the type I inositol 1,4,5-trisphosphate receptor by PKA and PKG. FEBS Lett (2004) 1.00
Efficient two-photon-sensitized luminescence of a europium(III) complex. Angew Chem Int Ed Engl (2005) 1.00
A high level of circulating HOTAIR is associated with progression and poor prognosis of cervical cancer. Tumour Biol (2014) 1.00
Inositol 1,4,5-trisphosphate receptor subtypes are differentially distributed between smooth muscle and endothelial layers of rat arteries. Cell Calcium (2004) 0.99
Identification of an epitope of SARS-coronavirus nucleocapsid protein. Cell Res (2003) 0.98
Identification and characterization of peptides that interact with hepatitis B virus via the putative receptor binding site. J Virol (2006) 0.98
Increased miR-195 aggravates neuropathic pain by inhibiting autophagy following peripheral nerve injury. Glia (2013) 0.98
Dec2 promotes Th2 cell differentiation by enhancing IL-2R signaling. J Immunol (2009) 0.97
The role of oxidized low-density lipoprotein in breaking peripheral Th17/Treg balance in patients with acute coronary syndrome. Biochem Biophys Res Commun (2010) 0.97
Paeoniflorin improves survival in LPS-challenged mice through the suppression of TNF-α and IL-1β release and augmentation of IL-10 production. Int Immunopharmacol (2010) 0.96
The essential light chain N-terminal extension alters force and fiber kinetics in mouse cardiac muscle. J Biol Chem (2005) 0.96
Matrine, a novel autophagy inhibitor, blocks trafficking and the proteolytic activation of lysosomal proteases. Carcinogenesis (2012) 0.96
An improved method of sample preparation on AnchorChip targets for MALDI-MS and MS/MS and its application in the liver proteome project. Proteomics (2007) 0.96
Transgenic quail as a model for research in the avian nervous system: a comparative study of the auditory brainstem. J Comp Neurol (2013) 0.96
Metropolitan all-pass and inter-city quantum communication network. Opt Express (2010) 0.96
Polymeric nanoparticles for nonviral gene therapy extend brain tumor survival in vivo. ACS Nano (2015) 0.96
Mass spectrometric analysis of type 1 inositol 1,4,5-trisphosphate receptor ubiquitination. J Biol Chem (2008) 0.95
Microarrays for the functional analysis of the chemical-kinase interactome. J Biomol Screen (2005) 0.95
Lycopene protects against trimethyltin-induced neurotoxicity in primary cultured rat hippocampal neurons by inhibiting the mitochondrial apoptotic pathway. Neurochem Int (2011) 0.95
Discovery of anti-inflammatory clinical candidate E6201, inspired from resorcylic lactone LL-Z1640-2, III. Bioorg Med Chem Lett (2010) 0.95
Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system. Mol Biol Cell (2012) 0.95
Paradoxical sleep deprivation impairs spatial learning and affects membrane excitability and mitochondrial protein in the hippocampus. Brain Res (2008) 0.94