Peter M Snyder

Author PubWeight™ 34.35‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neurons. Proc Natl Acad Sci U S A 2002 3.05
2 Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor. J Biol Chem 2008 2.00
3 Nedd4-2 catalyzes ubiquitination and degradation of cell surface ENaC. J Biol Chem 2007 1.81
4 Salt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2. Am J Physiol Renal Physiol 2008 1.60
5 Liddle's syndrome mutations increase Na+ transport through dual effects on epithelial Na+ channel surface expression and proteolytic cleavage. Proc Natl Acad Sci U S A 2006 1.60
6 Nedd4-2 induces endocytosis and degradation of proteolytically cleaved epithelial Na+ channels. J Biol Chem 2008 1.46
7 The kidney-specific WNK1 isoform is induced by aldosterone and stimulates epithelial sodium channel-mediated Na+ transport. Proc Natl Acad Sci U S A 2004 1.43
8 Extracellular chloride regulates the epithelial sodium channel. J Biol Chem 2009 1.40
9 Extracellular protons regulate human ENaC by modulating Na+ self-inhibition. J Biol Chem 2008 1.31
10 Oxidant regulated inter-subunit disulfide bond formation between ASIC1a subunits. Proc Natl Acad Sci U S A 2009 1.29
11 Ubiquitin-protein ligase WWP2 binds to and downregulates the epithelial Na(+) channel. Am J Physiol Renal Physiol 2002 1.23
12 Mutations of KCNJ10 together with mutations of SLC26A4 cause digenic nonsyndromic hearing loss associated with enlarged vestibular aqueduct syndrome. Am J Hum Genet 2009 1.16
13 Nedd4-2 phosphorylation induces serum and glucocorticoid-regulated kinase (SGK) ubiquitination and degradation. J Biol Chem 2004 1.13
14 Intracellular sodium regulates proteolytic activation of the epithelial sodium channel. J Biol Chem 2008 1.10
15 Identification of epithelial Na+ channel (ENaC) intersubunit Cl- inhibitory residues suggests a trimeric alpha gamma beta channel architecture. J Biol Chem 2010 1.03
16 Alternate promoters and variable splicing lead to hNedd4-2 isoforms with a C2 domain and varying number of WW domains. Am J Physiol Renal Physiol 2003 1.03
17 N-glycosylation of acid-sensing ion channel 1a regulates its trafficking and acidosis-induced spine remodeling. J Neurosci 2012 0.96
18 An evolutionarily conserved N-terminal Sgk1 variant with enhanced stability and improved function. Am J Physiol Renal Physiol 2008 0.92
19 Interaction of serum- and glucocorticoid regulated kinase 1 (SGK1) with the WW-domains of Nedd4-2 is required for epithelial sodium channel regulation. PLoS One 2010 0.87
20 Hrs controls sorting of the epithelial Na+ channel between endosomal degradation and recycling pathways. J Biol Chem 2010 0.86
21 Regulation of epithelial sodium channel trafficking by proprotein convertase subtilisin/kexin type 9 (PCSK9). J Biol Chem 2012 0.86
22 Ubiquitin-specific peptidase 8 (USP8) regulates endosomal trafficking of the epithelial Na+ channel. J Biol Chem 2013 0.86
23 The Drosophila gene CheB42a is a novel modifier of Deg/ENaC channel function. PLoS One 2010 0.85
24 Regulation of cardiac ATP-sensitive potassium channel surface expression by calcium/calmodulin-dependent protein kinase II. J Biol Chem 2012 0.82
25 Identification of extracellular domain residues required for epithelial Na+ channel activation by acidic pH. J Biol Chem 2012 0.81
26 A region directly following the second transmembrane domain in gamma ENaC is required for normal channel gating. J Biol Chem 2003 0.80
27 Acid-sensing ion channels (ASICs) are differentially modulated by anions dependent on their subunit composition. Am J Physiol Cell Physiol 2012 0.78
28 Intoxicated Na(+) channels. Focus on "ethanol stimulates epithelial sodium channels by elevating reactive oxygen species". Am J Physiol Cell Physiol 2012 0.77
29 Regulation of the delta and alpha epithelial sodium channel (ENaC) by ubiquitination and Nedd8. J Cell Physiol 2013 0.75