Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Three-dimensional structure of the bacterial cell wall peptidoglycan.
|
Proc Natl Acad Sci U S A
|
2006
|
2.81
|
2
|
How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function.
|
Proc Natl Acad Sci U S A
|
2013
|
1.75
|
3
|
Co-opting the cell wall in fighting methicillin-resistant Staphylococcus aureus: potent inhibition of PBP 2a by two anti-MRSA beta-lactam antibiotics.
|
J Am Chem Soc
|
2008
|
1.50
|
4
|
Synthetic peptidoglycan substrates for penicillin-binding protein 5 of Gram-negative bacteria.
|
J Org Chem
|
2004
|
1.33
|
5
|
Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins.
|
Proc Natl Acad Sci U S A
|
2007
|
1.27
|
6
|
Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane.
|
FASEB J
|
2011
|
1.25
|
7
|
Activation for catalysis of penicillin-binding protein 2a from methicillin-resistant Staphylococcus aureus by bacterial cell wall.
|
J Am Chem Soc
|
2005
|
1.22
|
8
|
Lytic transglycosylase MltB of Escherichia coli and its role in recycling of peptidoglycan strands of bacterial cell wall.
|
J Am Chem Soc
|
2008
|
1.21
|
9
|
Synthesis of a fragment of bacterial cell wall.
|
J Org Chem
|
2004
|
1.20
|
10
|
Total synthesis of N-acetylglucosamine-1,6-anhydro-N-acetylmuramylpentapeptide and evaluation of its turnover by AmpD from Escherichia coli.
|
J Am Chem Soc
|
2009
|
1.19
|
11
|
Active site ring-opening of a thiirane moiety and picomolar inhibition of gelatinases.
|
Chem Biol Drug Des
|
2009
|
1.11
|
12
|
Inhibition of MMP-9 by a selective gelatinase inhibitor protects neurovasculature from embolic focal cerebral ischemia.
|
Mol Neurodegener
|
2012
|
1.10
|
13
|
Reactions of the three AmpD enzymes of Pseudomonas aeruginosa.
|
J Am Chem Soc
|
2013
|
1.06
|
14
|
Elucidation of the molecular recognition of bacterial cell wall by modular pneumococcal phage endolysin CPL-1.
|
J Biol Chem
|
2007
|
1.06
|
15
|
Crystal structures of penicillin-binding protein 6 from Escherichia coli.
|
J Am Chem Soc
|
2009
|
1.05
|
16
|
Crystal structures of bacterial peptidoglycan amidase AmpD and an unprecedented activation mechanism.
|
J Biol Chem
|
2011
|
1.00
|
17
|
Mechanistic basis for the action of new cephalosporin antibiotics effective against methicillin- and vancomycin-resistant Staphylococcus aureus.
|
J Biol Chem
|
2006
|
1.00
|
18
|
Recognition of peptidoglycan and β-lactam antibiotics by the extracellular domain of the Ser/Thr protein kinase StkP from Streptococcus pneumoniae.
|
FEBS Lett
|
2010
|
0.96
|
19
|
Lysine Nzeta-decarboxylation switch and activation of the beta-lactam sensor domain of BlaR1 protein of methicillin-resistant Staphylococcus aureus.
|
J Biol Chem
|
2011
|
0.96
|
20
|
Selective water-soluble gelatinase inhibitor prodrugs.
|
J Med Chem
|
2011
|
0.95
|
21
|
Metabolism of (4-phenoxyphenylsulfonyl) methylthiirane, a selective gelatinase inhibitor.
|
Chem Biol Drug Des
|
2008
|
0.94
|
22
|
Shared functional attributes between the mecA gene product of Staphylococcus sciuri and penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus.
|
Biochemistry
|
2007
|
0.93
|
23
|
Structural and functional insights into peptidoglycan access for the lytic amidase LytA of Streptococcus pneumoniae.
|
MBio
|
2014
|
0.90
|
24
|
Synthesis, kinetic characterization and metabolism of diastereomeric 2-(1-(4-phenoxyphenylsulfonyl)ethyl)thiiranes as potent gelatinase and MT1-MMP inhibitors.
|
Chem Biol Drug Des
|
2009
|
0.88
|
25
|
Thermodynamics of interactions of vancomycin and synthetic surrogates of bacterial cell wall.
|
J Am Chem Soc
|
2006
|
0.87
|
26
|
Structure and cell wall cleavage by modular lytic transglycosylase MltC of Escherichia coli.
|
ACS Chem Biol
|
2014
|
0.83
|
27
|
Structural analysis of the role of Pseudomonas aeruginosa penicillin-binding protein 5 in β-lactam resistance.
|
Antimicrob Agents Chemother
|
2013
|
0.83
|
28
|
Inhibitors for Bacterial Cell-Wall Recycling.
|
ACS Med Chem Lett
|
2012
|
0.82
|
29
|
Complications from dual roles of sodium hydride as a base and as a reducing agent.
|
J Org Chem
|
2009
|
0.82
|
30
|
Strategy in inhibition of cathepsin B, a target in tumor invasion and metastasis.
|
J Am Chem Soc
|
2004
|
0.81
|
31
|
A chemical biological strategy to facilitate diabetic wound healing.
|
ACS Chem Biol
|
2013
|
0.81
|
32
|
Synthesis and NMR characterization of (Z,Z,Z,Z,E,E,ω)-heptaprenol.
|
J Am Chem Soc
|
2012
|
0.81
|
33
|
Facile preparation of a highly functionalized tetrahydropyran by catalytic hydrogenation of an oxazoline.
|
J Org Chem
|
2008
|
0.81
|
34
|
Regiospecific syntheses of 6alpha-(1R-Hydroxyoctyl)penicillanic acid and 6beta-(1R-hydroxyoctyl)penicillanic acid as mechanistic probes of class D beta-lactamases.
|
Org Lett
|
2009
|
0.79
|
35
|
Sulfonylation-induced N- to O-acetyl migration in 2-acetamidoethanol derivatives.
|
J Org Chem
|
2010
|
0.78
|
36
|
Water-soluble mmp-9 inhibitor prodrug generates active metabolites that cross the blood-brain barrier.
|
ACS Chem Neurosci
|
2013
|
0.77
|
37
|
Water-Soluble MMP-9 Inhibitor Reduces Lesion Volume after Severe Traumatic Brain Injury.
|
ACS Chem Neurosci
|
2015
|
0.76
|
38
|
Use of silver carbonate in the Wittig reaction.
|
J Org Chem
|
2013
|
0.75
|
39
|
Corrigendum: Muropeptides in Pseudomonas aeruginosa and their Role as Elicitors of β-Lactam-Antibiotic Resistance.
|
Angew Chem Int Ed Engl
|
2016
|
0.75
|
40
|
Turnover of Bacterial Cell Wall by SltB3, a Multidomain Lytic Transglycosylase of Pseudomonas aeruginosa.
|
ACS Chem Biol
|
2016
|
0.75
|