Published in J Org Chem on November 26, 2013
A catalytic asymmetric synthesis of chiral glycidic acid derivatives through chiral dioxirane-mediated catalytic asymmetric epoxidation of cinnamic acid derivatives. J Org Chem (2004) 1.36
A practical synthesis of nitrocefin. J Org Chem (2005) 1.07
Mechanically induced solid-state generation of phosphorus ylides and the solvent-free Wittig reaction. J Am Chem Soc (2002) 1.05
Wittig reactions in water media employing stabilized ylides with aldehydes. Synthesis of alpha,beta-unsaturated esters from mixing aldehydes, alpha-bromoesters, and Ph3P in aqueous NaHCO3. J Org Chem (2007) 1.03
Potassium hydride in paraffin: a useful base for organic synthesis. J Org Chem (2006) 1.03
Z-selective Horner-Wadsworth-Emmons reaction of ethyl (diarylphosphono)acetates using sodium iodide and DBU J Org Chem (2000) 0.84
Use of lithium hexafluoroisopropoxide as a mild base for Horner-Wadsworth-Emmons olefination of epimerizable aldehydes. Org Lett (2005) 0.83
A direct phosphine-mediated synthesis of pyrroles from acid chlorides and alpha,beta-unsaturated imines. Org Lett (2009) 0.83
Stereoselective synthesis of 3-alkyl-2-aryltetrahydrofuran-4-ols: total synthesis of (+/-)-paulownin. J Org Chem (2008) 0.81
Generation of phosphoranes derived from phosphites. A new class of phosphorus ylides leading to high E selectivity with semi-stabilizing groups in Wittig olefinations. J Am Chem Soc (2003) 0.81
Combinatorial Knoevenagel reactions. J Comb Chem (2007) 0.81
P[N(i-Bu)CH(2)CH(2)](3)N: nonionic Lewis base for promoting the room-temperature synthesis of α,β-unsaturated esters, fluorides, ketones, and nitriles using Wadsworth-Emmons phosphonates. J Org Chem (2010) 0.81
Strong bicyclic guanidine base-promoted wittig and horner-wadsworth-emmons reactions Org Lett (2000) 0.81
Complete 1H and 13C NMR assignment of trans,trans-2,3-divinylfuran derivatives. Magn Reson Chem (2007) 0.79
Pd-catalyzed dearboxylative Heck coupling with dioxygen as the terminal oxidant. Org Lett (2010) 0.79
Stereoselective synthesis of unsaturated and functionalized L-NHBoc amino acids, using Wittig reaction under mild phase-transfer conditions. J Org Chem (2012) 0.78
Microwave-assisted, aqueous wittig reactions: organic-solvent- and protecting-group-free chemoselective synthesis of functionalized alkenes. Chemistry (2010) 0.78
Amine- and sulfonamide-promoted Wittig olefination reactions in water. Chemistry (2011) 0.77
Preparation of tetrasubstituted furans via intramolecular Wittig reactions with phosphorus ylides as intermediates. Org Lett (2010) 0.77
Bacterial resistance to beta-lactam antibiotics: compelling opportunism, compelling opportunity. Chem Rev (2005) 4.48
Tackling antibiotic resistance. Nat Rev Microbiol (2011) 3.95
Versatility of aminoglycosides and prospects for their future. Clin Microbiol Rev (2003) 3.72
Three-dimensional structure of the bacterial cell wall peptidoglycan. Proc Natl Acad Sci U S A (2006) 2.81
A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia. J Neurosci (2005) 2.54
Epidemiological expansion, structural studies, and clinical challenges of new β-lactamases from gram-negative bacteria. Annu Rev Microbiol (2011) 2.53
Effect of ablation or inhibition of stromal matrix metalloproteinase-9 on lung metastasis in a breast cancer model is dependent on genetic background. Cancer Res (2008) 1.88
Potent mechanism-based inhibitors for matrix metalloproteinases. J Biol Chem (2005) 1.83
Dichlorobis(1-ethylimidazole)zinc(II). Acta Crystallogr Sect E Struct Rep Online (2007) 1.79
How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function. Proc Natl Acad Sci U S A (2013) 1.75
The basis for resistance to beta-lactam antibiotics by penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus. J Biol Chem (2004) 1.74
Ab initio QM/MM study of class A beta-lactamase acylation: dual participation of Glu166 and Lys73 in a concerted base promotion of Ser70. J Am Chem Soc (2005) 1.67
Recent advances in MMP inhibitor design. Cancer Metastasis Rev (2006) 1.66
2-(Thio-phen-2-yl)-1-(thio-phen-2-ylmeth-yl)-1H-benzimidazole. Acta Crystallogr Sect E Struct Rep Online (2012) 1.64
Bacterial cell-wall recycling. Ann N Y Acad Sci (2012) 1.60
Molecular basis and phenotype of methicillin resistance in Staphylococcus aureus and insights into new beta-lactams that meet the challenge. Antimicrob Agents Chemother (2009) 1.51
Design and characterization of a metalloproteinase inhibitor-tethered resin for the detection of active MMPs in biological samples. Chem Biol (2006) 1.50
Cyanide: a strong-field ligand for ferrohemes and hemoproteins? Angew Chem Int Ed Engl (2008) 1.50
Co-opting the cell wall in fighting methicillin-resistant Staphylococcus aureus: potent inhibition of PBP 2a by two anti-MRSA beta-lactam antibiotics. J Am Chem Soc (2008) 1.50
Cell surface association of matrix metalloproteinase-9 (gelatinase B). Cancer Metastasis Rev (2003) 1.45
Squaraine-derived rotaxanes: sterically protected fluorescent near-IR dyes. J Am Chem Soc (2005) 1.44
Aminoglycosides modified by resistance enzymes display diminished binding to the bacterial ribosomal aminoacyl-tRNA site. Chem Biol (2002) 1.42
Resistance to beta-lactam antibiotics and its mediation by the sensor domain of the transmembrane BlaR signaling pathway in Staphylococcus aureus. J Biol Chem (2003) 1.38
The future of the β-lactams. Curr Opin Microbiol (2010) 1.36
Antimetastatic activity of a novel mechanism-based gelatinase inhibitor. Cancer Res (2005) 1.36
High-resolution X-ray structure of an acyl-enzyme species for the class D OXA-10 beta-lactamase. J Am Chem Soc (2002) 1.36
Synthetic peptidoglycan substrates for penicillin-binding protein 5 of Gram-negative bacteria. J Org Chem (2004) 1.33
Self-assembly of fluorescent inclusion complexes in competitive media including the interior of living cells. J Am Chem Soc (2007) 1.33
{Bis[2-(diphenyl-phosphino)eth-yl]phenyl-phosphine-κP,P',P''}chloridoplatinium(II) hexa-fluoridophosphate. Acta Crystallogr Sect E Struct Rep Online (2009) 1.32
Structural consequences of the inhibitor-resistant Ser130Gly substitution in TEM beta-lactamase. Biochemistry (2005) 1.32
Inhibition of human prostate cancer growth, osteolysis and angiogenesis in a bone metastasis model by a novel mechanism-based selective gelatinase inhibitor. Int J Cancer (2006) 1.32
Bacterial AmpD at the crossroads of peptidoglycan recycling and manifestation of antibiotic resistance. J Am Chem Soc (2009) 1.31
Activation of BlaR1 protein of methicillin-resistant Staphylococcus aureus, its proteolytic processing, and recovery from induction of resistance. J Biol Chem (2011) 1.30
Mechanistic characterization of the bifunctional aminoglycoside-modifying enzyme AAC(3)-Ib/AAC(6')-Ib' from Pseudomonas aeruginosa. Biochemistry (2007) 1.28
Mechanistic basis for the emergence of catalytic competence against carbapenem antibiotics by the GES family of beta-lactamases. J Biol Chem (2009) 1.28
Iminonitroso Diels-Alder reactions for efficient derivatization and functionalization of complex diene-containing natural products. Org Lett (2007) 1.28
Discoidin domain receptors: unique receptor tyrosine kinases in collagen-mediated signaling. J Biol Chem (2013) 1.27
Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins. Proc Natl Acad Sci U S A (2007) 1.27
Extracellular proteases as targets for treatment of cancer metastases. Chem Soc Rev (2004) 1.26
Characterization of the bifunctional aminoglycoside-modifying enzyme ANT(3'')-Ii/AAC(6')-IId from Serratia marcescens. Biochemistry (2006) 1.25
Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram-negative bacterial outer membrane. FASEB J (2011) 1.25
Design of novel antibiotics that bind to the ribosomal acyltransfer site. J Am Chem Soc (2002) 1.23
Mutational replacement of Leu-293 in the class C Enterobacter cloacae P99 beta-lactamase confers increased MIC of cefepime. Antimicrob Agents Chemother (2002) 1.23
The importance of a critical protonation state and the fate of the catalytic steps in class A beta-lactamases and penicillin-binding proteins. J Biol Chem (2004) 1.22
Activation for catalysis of penicillin-binding protein 2a from methicillin-resistant Staphylococcus aureus by bacterial cell wall. J Am Chem Soc (2005) 1.22
Reactions of all Escherichia coli lytic transglycosylases with bacterial cell wall. J Am Chem Soc (2013) 1.21
Lytic transglycosylase MltB of Escherichia coli and its role in recycling of peptidoglycan strands of bacterial cell wall. J Am Chem Soc (2008) 1.21
Source of phosphate in the enzymic reaction as a point of distinction among aminoglycoside 2''-phosphotransferases. J Biol Chem (2009) 1.21
Synthesis of a fragment of bacterial cell wall. J Org Chem (2004) 1.20
Inhibition of histone deacetylases: a pharmacological approach to the treatment of non-cancer disorders. Curr Top Med Chem (2009) 1.20
Total synthesis of N-acetylglucosamine-1,6-anhydro-N-acetylmuramylpentapeptide and evaluation of its turnover by AmpD from Escherichia coli. J Am Chem Soc (2009) 1.19
Molecular structures and dynamics of the stepwise activation mechanism of a matrix metalloproteinase zymogen: challenging the cysteine switch dogma. J Am Chem Soc (2007) 1.19
The complex of a designer antibiotic with a model aminoacyl site of the 30S ribosomal subunit revealed by X-ray crystallography. J Am Chem Soc (2003) 1.18
Messenger functions of the bacterial cell wall-derived muropeptides. Biochemistry (2012) 1.17
Discrete steps in sensing of beta-lactam antibiotics by the BlaR1 protein of the methicillin-resistant Staphylococcus aureus bacterium. Proc Natl Acad Sci U S A (2006) 1.17
Three decades of the class A beta-lactamase acyl-enzyme. Curr Protein Pept Sci (2009) 1.17
Proton-mediated electron configuration change in high-spin iron(II) porphyrinates. J Am Chem Soc (2005) 1.17
X-ray crystal structure of the acylated beta-lactam sensor domain of BlaR1 from Staphylococcus aureus and the mechanism of receptor activation for signal transduction. J Am Chem Soc (2004) 1.15
Evolution of natural product scaffolds by acyl- and arylnitroso hetero-diels-alder reactions: new chemistry on piperine. J Org Chem (2008) 1.14
Singlet oxygen generation using iodinated squaraine and squaraine-rotaxane dyes. New J Chem (2007) 1.14
Heme carbonyls: environmental effects on nu(C-O) and Fe-C/C-O bond length correlations. J Am Chem Soc (2005) 1.13
Synthetic peptidoglycan motifs for germination of bacterial spores. Chembiochem (2010) 1.12
Complex pattern of membrane type 1 matrix metalloproteinase shedding. Regulation by autocatalytic cells surface inactivation of active enzyme. J Biol Chem (2002) 1.12
Active site ring-opening of a thiirane moiety and picomolar inhibition of gelatinases. Chem Biol Drug Des (2009) 1.11