| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes.
|
Endocr Rev
|
2002
|
6.05
|
|
2
|
Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes.
|
Nat Genet
|
2005
|
4.44
|
|
3
|
Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?
|
Diabetes
|
2003
|
4.40
|
|
4
|
The molecular basis for oxidative stress-induced insulin resistance.
|
Antioxid Redox Signal
|
2005
|
2.46
|
|
5
|
Functional variants of the HMGA1 gene and type 2 diabetes mellitus.
|
JAMA
|
2011
|
2.00
|
|
6
|
Nordihydroguaiaretic acid (NDGA) inhibits the IGF-1 and c-erbB2/HER2/neu receptors and suppresses growth in breast cancer cells.
|
Breast Cancer Res Treat
|
2005
|
1.72
|
|
7
|
Decreased insulin receptor (IR) autophosphorylation in fibroblasts from patients with PCOS: effects of serine kinase inhibitors and IR activators.
|
J Clin Endocrinol Metab
|
2002
|
1.67
|
|
8
|
IGF-binding protein-1 levels are related to insulin-mediated glucose disposal and are a potential serum marker of insulin resistance.
|
Diabetes Care
|
2006
|
1.52
|
|
9
|
Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance.
|
Diabetes
|
2005
|
1.24
|
|
10
|
Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes.
|
Diabetes Metab Res Rev
|
2007
|
1.19
|
|
11
|
Overexpression of the insulin receptor inhibitor PC-1/ENPP1 induces insulin resistance and hyperglycemia.
|
Am J Physiol Endocrinol Metab
|
2005
|
1.14
|
|
12
|
Diarylureas are small-molecule inhibitors of insulin-like growth factor I receptor signaling and breast cancer cell growth.
|
Mol Cancer Ther
|
2006
|
1.02
|
|
13
|
A fully human, allosteric monoclonal antibody that activates the insulin receptor and improves glycemic control.
|
Diabetes
|
2012
|
1.01
|
|
14
|
Insulin and hybrid insulin/IGF receptors are major regulators of breast cancer cells.
|
Breast Dis
|
2003
|
0.99
|
|
15
|
Technical evaluation of in vivo abdominal fat and IMCL quantification using MRI and MRSI at 3 T.
|
Magn Reson Imaging
|
2007
|
0.98
|
|
16
|
Insulin resistance in non-obese subjects is associated with activation of the JNK pathway and impaired insulin signaling in skeletal muscle.
|
PLoS One
|
2011
|
0.97
|
|
17
|
Expression of insulin-like growth factor-1 receptor in local and metastatic prostate cancer.
|
Urol Oncol
|
2007
|
0.97
|
|
18
|
A polymorphism of HMGA1 is associated with increased risk of metabolic syndrome and related components.
|
Sci Rep
|
2013
|
0.90
|
|
19
|
Regulation of insulin receptor function by a small molecule insulin receptor activator.
|
J Biol Chem
|
2002
|
0.90
|
|
20
|
Influence of gender on the relationship between insulin sensitivity, adiposity, and plasma lipids in lean nondiabetic subjects.
|
Metabolism
|
2009
|
0.89
|
|
21
|
Nordihydroguaiaretic acid (NDGA), an inhibitor of the HER2 and IGF-1 receptor tyrosine kinases, blocks the growth of HER2-overexpressing human breast cancer cells.
|
J Cell Biochem
|
2008
|
0.89
|
|
22
|
A pilot dose-escalation study of the effects of nordihydroguareacetic acid on hormone and prostate specific antigen levels in patients with relapsed prostate cancer.
|
BJU Int
|
2008
|
0.88
|
|
23
|
Novel approach to treat insulin resistance, type 2 diabetes, and the metabolic syndrome: simultaneous activation of PPARalpha, PPARgamma, and PPARdelta.
|
Curr Diabetes Rev
|
2005
|
0.86
|
|
24
|
Nordihydroguaiaretic acid inhibits insulin-like growth factor signaling, growth, and survival in human neuroblastoma cells.
|
J Cell Biochem
|
2007
|
0.86
|
|
25
|
Pharmacokinetics, tolerability, and fructosamine-lowering effect of a novel, controlled-release formulation of alpha-lipoic acid.
|
Endocr Pract
|
2002
|
0.85
|
|
26
|
Gender differences in the relationship of ENPP1/PC-1 variants to obesity in a Turkish population.
|
Obesity (Silver Spring)
|
2008
|
0.85
|
|
27
|
Parallel synthesis of diarylureas and their evaluation as inhibitors of insulin-like growth factor receptor.
|
J Comb Chem
|
2006
|
0.84
|
|
28
|
Evidence that an HMGA1 gene variant associates with type 2 diabetes, body mass index, and high-density lipoprotein cholesterol in a Hispanic-American population.
|
Metab Syndr Relat Disord
|
2013
|
0.83
|
|
29
|
Comment on: Marquez et al. Low-frequency variants in HMGA1 are not associated with type 2 diabetes risk. Diabetes 2012;61:524-530.
|
Diabetes
|
2012
|
0.83
|
|
30
|
Detailed mechanistic analysis of gevokizumab, an allosteric anti-IL-1β antibody with differential receptor-modulating properties.
|
J Pharmacol Exp Ther
|
2013
|
0.81
|
|
31
|
Genetic variants of the ENPP1/PC-1 gene are associated with hypertriglyceridemia in male subjects.
|
Metab Syndr Relat Disord
|
2009
|
0.81
|
|
32
|
Effective treatments for insulin resistance: trim the fat and douse the fire.
|
Trends Endocrinol Metab
|
2004
|
0.79
|
|
33
|
In vitro and in vivo prevention of HIV protease inhibitor-induced insulin resistance by a novel small molecule insulin receptor activator.
|
J Cell Biochem
|
2004
|
0.79
|
|
34
|
Analysis of insulin-stimulated insulin receptor activation and glucose transport in cultured skeletal muscle cells from obese subjects.
|
Metabolism
|
2005
|
0.79
|
|
35
|
Inhibitory effects of nordihydroguaiaretic acid (NDGA) on the IGF-1 receptor and androgen dependent growth of LAPC-4 prostate cancer cells.
|
Prostate
|
2008
|
0.79
|
|
36
|
Elevated plasma cell membrane glycoprotein levels and diminished insulin receptor autophosphorylation in obese, insulin-resistant rhesus monkeys.
|
Metabolism
|
2002
|
0.78
|
|
37
|
Insulin autoimmune syndrome (Hirata Disease) in European Caucasians taking α-lipoic acid.
|
Clin Endocrinol (Oxf)
|
2013
|
0.78
|
|
38
|
Aging and insulin resistance: just say iNOS.
|
Diabetes
|
2013
|
0.78
|
|
39
|
XOMA 052, an anti-IL-1β monoclonal antibody, prevents IL-1β-mediated insulin resistance in 3T3-L1 adipocytes.
|
Obesity (Silver Spring)
|
2013
|
0.78
|
|
40
|
Inadvertent sulfonylurea overdosage and hypoglycemia in an elderly woman: failure of serum hypoglycemia screening.
|
Diabetes Technol Ther
|
2003
|
0.77
|
|
41
|
Design, synthesis, and structure-activity relationships of novel insulin receptor tyrosine kinase activators.
|
J Med Chem
|
2008
|
0.76
|
|
42
|
Effects of controlled-release alpha lipoic acid in lean, nondiabetic patients with polycystic ovary syndrome.
|
J Diabetes Sci Technol
|
2010
|
0.76
|
|
43
|
Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity.
|
BMC Endocr Disord
|
2012
|
0.75
|