Published in Metab Syndr Relat Disord on October 22, 2013
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The molecular basis for oxidative stress-induced insulin resistance. Antioxid Redox Signal (2005) 2.46
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Functional variants of the HMGA1 gene and type 2 diabetes mellitus. JAMA (2011) 2.00
Identification of four gene variants associated with myocardial infarction. Am J Hum Genet (2005) 1.89
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Replication study of 10 genetic polymorphisms associated with coronary heart disease in a specific high-risk population with familial hypercholesterolemia. Eur Heart J (2008) 1.80
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Five common gene variants identify elevated genetic risk for coronary heart disease. Genet Med (2007) 1.72
Nordihydroguaiaretic acid (NDGA) inhibits the IGF-1 and c-erbB2/HER2/neu receptors and suppresses growth in breast cancer cells. Breast Cancer Res Treat (2005) 1.72
Flavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in healthy adults. J Am Coll Nutr (2004) 1.71
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Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice. Nat Med (2005) 1.64
Gene variants of VAMP8 and HNRPUL1 are associated with early-onset myocardial infarction. Arterioscler Thromb Vasc Biol (2006) 1.60
Lack of support for the association between GAD2 polymorphisms and severe human obesity. PLoS Biol (2005) 1.59
Insulin resistance and cancer risk: an overview of the pathogenetic mechanisms. Exp Diabetes Res (2012) 1.55
IGF-binding protein-1 levels are related to insulin-mediated glucose disposal and are a potential serum marker of insulin resistance. Diabetes Care (2006) 1.52
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Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy. Heart Rhythm (2012) 1.49
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Apoa5 Q139X truncation predisposes to late-onset hyperchylomicronemia due to lipoprotein lipase impairment. J Clin Invest (2005) 1.37
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A nucleoprotein complex containing Sp1, C/EBP beta, and HMGI-Y controls human insulin receptor gene transcription. Mol Cell Biol (2003) 1.30
Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study. Hum Mol Genet (2008) 1.30
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Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance. Diabetes (2005) 1.24
Regulated expression of apolipoprotein E by human retinal pigment epithelial cells. J Lipid Res (2003) 1.23
GOSR2 Lys67Arg is associated with hypertension in whites. Am J Hypertens (2008) 1.20
Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes. Diabetes Metab Res Rev (2007) 1.19
Pseudogene-mediated posttranscriptional silencing of HMGA1 can result in insulin resistance and type 2 diabetes. Nat Commun (2010) 1.17
Analysis of 17,576 potentially functional SNPs in three case-control studies of myocardial infarction. PLoS One (2008) 1.17
Overexpression of the insulin receptor inhibitor PC-1/ENPP1 induces insulin resistance and hyperglycemia. Am J Physiol Endocrinol Metab (2005) 1.14
Relation of increased prebeta-1 high-density lipoprotein levels to risk of coronary heart disease. Am J Cardiol (2011) 1.09
HDL antielastase activity prevents smooth muscle cell anoikis, a potential new antiatherogenic property. FASEB J (2009) 1.08
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Increased O-glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic beta-cells. FASEB J (2004) 1.07
Disruption of a novel Kruppel-like transcription factor p300-regulated pathway for insulin biosynthesis revealed by studies of the c.-331 INS mutation found in neonatal diabetes mellitus. J Biol Chem (2011) 1.06
WW-domain-containing oxidoreductase is associated with low plasma HDL-C levels. Am J Hum Genet (2008) 1.06
Prebeta-1 HDL and coronary heart disease. Curr Opin Lipidol (2012) 1.06
Mechanisms of statin-induced myalgia assessed by physiogenomic associations. Atherosclerosis (2011) 1.05
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Morphology and structure of lipoproteins revealed by an optimized negative-staining protocol of electron microscopy. J Lipid Res (2010) 1.04
The cAMP-HMGA1-RBP4 system: a novel biochemical pathway for modulating glucose homeostasis. BMC Biol (2009) 1.04
Diarylureas are small-molecule inhibitors of insulin-like growth factor I receptor signaling and breast cancer cell growth. Mol Cancer Ther (2006) 1.02
An apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients. J Lipid Res (2008) 1.02
A fully human, allosteric monoclonal antibody that activates the insulin receptor and improves glycemic control. Diabetes (2012) 1.01
Apolipoprotein E e4 allele increases the risk of early postoperative delirium in older patients undergoing noncardiac surgery. Anesthesiology (2007) 0.99
Insulin and hybrid insulin/IGF receptors are major regulators of breast cancer cells. Breast Dis (2003) 0.99
Technical evaluation of in vivo abdominal fat and IMCL quantification using MRI and MRSI at 3 T. Magn Reson Imaging (2007) 0.98
Chronic hyperglycemia impairs insulin secretion by affecting insulin receptor expression, splicing, and signaling in RIN beta cell line and human islets of Langerhans. FASEB J (2003) 0.98
High-density lipoprotein metabolism and the human embryo. Hum Reprod Update (2009) 0.98
Assessment of atherosclerotic risk factors and endothelial function in children and young adults with pediatric-onset systemic lupus erythematosus. Arthritis Rheum (2004) 0.98
Insulin resistance in non-obese subjects is associated with activation of the JNK pathway and impaired insulin signaling in skeletal muscle. PLoS One (2011) 0.97
Expression of insulin-like growth factor-1 receptor in local and metastatic prostate cancer. Urol Oncol (2007) 0.97
Apolipoproteins A-IV and A-V are acute-phase proteins in mouse HDL. Atherosclerosis (2004) 0.96
Regulation of apoAI processing by procollagen C-proteinase enhancer-2 and bone morphogenetic protein-1. J Lipid Res (2009) 0.95
New molecular insights into CETP structure and function: a review. J Lipid Res (2012) 0.94
HMGA1 is a novel downstream nuclear target of the insulin receptor signaling pathway. Sci Rep (2012) 0.92