Joshua T Mendell

Author PubWeight™ 147.80‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 c-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005 31.81
2 Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol Cell 2007 14.58
3 c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism. Nature 2009 13.28
4 Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 2009 11.10
5 Widespread microRNA repression by Myc contributes to tumorigenesis. Nat Genet 2007 10.78
6 Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster. Nat Genet 2006 7.53
7 Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology 2006 7.06
8 A hexanucleotide element directs microRNA nuclear import. Science 2007 5.71
9 MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1. Proc Natl Acad Sci U S A 2008 5.15
10 Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation. Proc Natl Acad Sci U S A 2009 3.76
11 microRNAs in vertebrate physiology and human disease. Annu Rev Genomics Hum Genet 2007 3.63
12 Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. J Clin Invest 2012 3.14
13 P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis. Proc Natl Acad Sci U S A 2010 2.49
14 miR-21: an androgen receptor-regulated microRNA that promotes hormone-dependent and hormone-independent prostate cancer growth. Cancer Res 2009 2.39
15 Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. Genes Dev 2010 2.37
16 MicroRNA miR-155 is a biomarker of early pancreatic neoplasia. Cancer Biol Ther 2009 2.01
17 Cell-cell contact globally activates microRNA biogenesis. Proc Natl Acad Sci U S A 2009 1.89
18 Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. Mol Cancer Ther 2011 1.76
19 Epigenetic silencing of MicroRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer. Pancreatology 2009 1.76
20 A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells. Cancer Biol Ther 2009 1.61
21 Myc: Maestro of MicroRNAs. Genes Cancer 2010 1.58
22 Circular reasoning: microRNAs and cell-cycle control. Trends Biochem Sci 2008 1.41
23 Analysis of regulatory network topology reveals functionally distinct classes of microRNAs. Nucleic Acids Res 2008 1.36
24 Functional integration of microRNAs into oncogenic and tumor suppressor pathways. Cell Cycle 2008 1.33
25 Identification of miR-21 targets in breast cancer cells using a quantitative proteomic approach. Proteomics 2009 1.28
26 Role of pri-miRNA tertiary structure in miR-17~92 miRNA biogenesis. RNA Biol 2011 1.20
27 Noncoding RNAs and cancer. Cell 2013 1.16
28 c-Myb oncoprotein is an essential target of the dleu2 tumor suppressor microRNA cluster. Cancer Biol Ther 2008 1.15
29 Identifying targets of miR-143 using a SILAC-based proteomic approach. Mol Biosyst 2010 1.12
30 PIPE-CLIP: a comprehensive online tool for CLIP-seq data analysis. Genome Biol 2014 1.03
31 KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation. Blood 2011 0.99
32 Abate and switch: miR-145 in stem cell differentiation. Cell 2009 0.96
33 A novel source for miR-21 expression through the alternative polyadenylation of VMP1 gene transcripts. Nucleic Acids Res 2012 0.93
34 Identification of miR-145 targets through an integrated omics analysis. Mol Biosyst 2014 0.77
35 Quantification of global microRNA abundance by selective isotachophoresis. Anal Chem 2010 0.76
36 Seeing through the miRage of tissue complexity. Cell Cycle 2014 0.75
37 When 19 is greater than 92. Elife 2013 0.75
38 MicroRNA-29 overexpression by adeno-associated virus suppresses fibrosis and restores muscle function in combination with micro-dystrophin. JCI Insight 2017 0.75