Published in Annu Rev Genomics Hum Genet on January 01, 2007
miR-182-mediated downregulation of BRCA1 impacts DNA repair and sensitivity to PARP inhibitors. Mol Cell (2010) 3.27
Posttranscriptional regulation of miRNAs harboring conserved terminal loops. Mol Cell (2008) 3.23
Active turnover modulates mature microRNA activity in Caenorhabditis elegans. Nature (2009) 3.03
Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1. J Biol Chem (2008) 3.00
MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase mind bomb-1. Stem Cells (2010) 2.89
microRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia. J Exp Med (2010) 2.68
Examination of the expanding pathways for the regulation of p21 expression and activity. Cell Signal (2010) 2.44
MicroRNAs as novel regulators of angiogenesis. Circ Res (2009) 2.33
miR-375 targets 3'-phosphoinositide-dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic beta-cells. Diabetes (2008) 2.23
MicroRNA target prediction by expression analysis of host genes. Genome Res (2008) 2.21
Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing. Proc Natl Acad Sci U S A (2011) 2.21
MicroRNA miR-155 is a biomarker of early pancreatic neoplasia. Cancer Biol Ther (2009) 2.01
Myc-regulated microRNAs attenuate embryonic stem cell differentiation. EMBO J (2009) 1.94
A set of differentially expressed miRNAs, including miR-30a-5p, act as post-transcriptional inhibitors of BDNF in prefrontal cortex. Hum Mol Genet (2008) 1.87
Alterations in microRNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction. Diabetes (2008) 1.85
Structural bias in T4 RNA ligase-mediated 3'-adapter ligation. Nucleic Acids Res (2012) 1.81
Involvement of microRNAs in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic beta-cells. Diabetes (2010) 1.80
MicroRNAs and their role in progressive kidney diseases. Clin J Am Soc Nephrol (2009) 1.77
miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition. Cell Death Differ (2011) 1.77
Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. Mol Cancer Ther (2011) 1.76
MicroRNA profiling and head and neck cancer. Comp Funct Genomics (2009) 1.68
microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells. PLoS One (2009) 1.67
Cloning and expression profiling of small RNAs expressed in the mouse ovary. RNA (2007) 1.65
MiRenSVM: towards better prediction of microRNA precursors using an ensemble SVM classifier with multi-loop features. BMC Bioinformatics (2010) 1.63
MicroRNA regulation of IFN-beta protein expression: rapid and sensitive modulation of the innate immune response. J Immunol (2010) 1.61
MicroRNA: Implications for Alzheimer Disease and other Human CNS Disorders. Curr Genomics (2009) 1.60
MicroRNA-196: critical roles and clinical applications in development and cancer. J Cell Mol Med (2011) 1.59
The exoribonuclease Nibbler controls 3' end processing of microRNAs in Drosophila. Curr Biol (2011) 1.56
Posttranscriptional control of neuronal development by microRNA networks. Trends Neurosci (2007) 1.56
Tracking Distinct RNA Populations Using Efficient and Reversible Covalent Chemistry. Mol Cell (2015) 1.56
MicroRNAs in cardiovascular disease: from pathogenesis to prevention and treatment. J Clin Invest (2013) 1.55
Transcriptional mechanism for the paired miR-433 and miR-127 genes by nuclear receptors SHP and ERRgamma. Nucleic Acids Res (2008) 1.50
Deep sequencing of microRNA precursors reveals extensive 3' end modification. RNA (2011) 1.49
microRNAs and cholesterol metabolism. Trends Endocrinol Metab (2010) 1.49
Many ways to generate microRNA-like small RNAs: non-canonical pathways for microRNA production. Mol Genet Genomics (2010) 1.48
Dicer controls CD8+ T-cell activation, migration, and survival. Proc Natl Acad Sci U S A (2010) 1.43
Enhancing miRNA annotation confidence in miRBase by continuous cross dataset analysis. RNA Biol (2011) 1.40
Population differences in microRNA expression and biological implications. RNA Biol (2011) 1.33
RNAase-III enzyme Dicer maintains signaling pathways for differentiation and survival in mouse cortical neural stem cells. J Cell Sci (2010) 1.33
Smooth muscle miRNAs are critical for post-natal regulation of blood pressure and vascular function. PLoS One (2011) 1.33
Aberrant MicroRNA-155 expression is an early event in the multistep progression of pancreatic adenocarcinoma. Pancreatology (2010) 1.31
Lineage-specific transcriptional regulation of DICER by MITF in melanocytes. Cell (2010) 1.31
The role of microRNAs in cholesterol efflux and hepatic lipid metabolism. Annu Rev Nutr (2011) 1.30
MicroRNA-34a is induced via p53 during cisplatin nephrotoxicity and contributes to cell survival. Mol Med (2010) 1.25
miRNAs: effectors of environmental influences on gene expression and disease. Toxicol Sci (2008) 1.21
Combined agonist-antagonist genome-wide functional screening identifies broadly active antiviral microRNAs. Proc Natl Acad Sci U S A (2010) 1.20
Identification of the receptor tyrosine kinase AXL in breast cancer as a target for the human miR-34a microRNA. Breast Cancer Res Treat (2011) 1.19
Identification of small molecules that suppress microRNA function and reverse tumorigenesis. J Biol Chem (2010) 1.19
MiR-205 silences MED1 in hypoxic primary human trophoblasts. FASEB J (2010) 1.17
Rapid evolution of mammalian X-linked testis microRNAs. BMC Genomics (2009) 1.17
Ets-1 and Ets-2 regulate the expression of microRNA-126 in endothelial cells. Arterioscler Thromb Vasc Biol (2010) 1.17
The evolution of core proteins involved in microRNA biogenesis. BMC Evol Biol (2008) 1.14
Endothelial dysfunction in the regulation of cirrhosis and portal hypertension. Liver Int (2011) 1.12
Decreased dyskerin levels as a mechanism of telomere shortening in X-linked dyskeratosis congenita. J Med Genet (2011) 1.11
Retracted Comparative expression profile of miRNA and mRNA in primary peripheral blood mononuclear cells infected with human immunodeficiency virus (HIV-1). PLoS One (2011) 1.09
Sex differences in microRNA regulation of gene expression: no smoke, just miRs. Biol Sex Differ (2012) 1.08
Regulation of let-7 and its target oncogenes (Review). Oncol Lett (2012) 1.06
MicroRNA binding site polymorphisms as biomarkers of cancer risk. Expert Rev Mol Diagn (2010) 1.06
Epigenetic changes in patients with multiple sclerosis. Nat Rev Neurol (2012) 1.05
The role of miR-26 in tumors and normal tissues (Review). Oncol Lett (2011) 1.05
Regulation of stem cell populations by microRNAs. Adv Exp Med Biol (2013) 1.04
The Influence of 3'UTRs on MicroRNA Function Inferred from Human SNP Data. Comp Funct Genomics (2011) 1.00
Role of microRNA-138 as a potential tumor suppressor in head and neck squamous cell carcinoma. Int Rev Cell Mol Biol (2013) 1.00
Numerical modelling of microRNA-mediated mRNA decay identifies novel mechanism of microRNA controlled mRNA downregulation. Nucleic Acids Res (2010) 0.99
Extracellular small RNAs: what, where, why? Biochem Soc Trans (2012) 0.98
Insight into microRNA regulation by analyzing the characteristics of their targets in humans. BMC Genomics (2009) 0.98
Analysis of microRNAs expressions in chondrosarcoma. J Orthop Res (2013) 0.98
MicroRNA-196a is a putative diagnostic biomarker and therapeutic target for laryngeal cancer. PLoS One (2013) 0.98
Microarray and deep sequencing cross-platform analysis of the mirRNome and isomiR variation in response to epidermal growth factor. BMC Genomics (2013) 0.97
Salivary biomarkers for detection of oral squamous cell carcinoma - current state and recent advances. Curr Oral Health Rep (2014) 0.96
HOCTAR database: a unique resource for microRNA target prediction. Gene (2011) 0.96
Novel therapeutic targets for pancreatic cancer. World J Gastroenterol (2014) 0.96
MicroRNA Expression Profile in CAD Patients and the Impact of ACEI/ARB. Cardiol Res Pract (2011) 0.96
Regulation of microRNA biogenesis and turnover by animals and their viruses. Cell Mol Life Sci (2013) 0.95
What are genes "for" or where are traits "from"? What is the question? Bioessays (2009) 0.94
MicroRNAs in nonalcoholic fatty liver disease: novel biomarkers and prognostic tools during the transition from steatosis to hepatocarcinoma. Biomed Res Int (2014) 0.94
Small RNA expression profiling by high-throughput sequencing: implications of enzymatic manipulation. J Nucleic Acids (2012) 0.94
MicroRNA 223 is upregulated in the multistep progression of Barrett's esophagus and modulates sensitivity to chemotherapy by targeting PARP1. Clin Cancer Res (2013) 0.93
Differences in microRNA detection levels are technology and sequence dependent. RNA (2013) 0.93
Pro-apoptotic miRNA-128-2 modulates ABCA1, ABCG1 and RXRα expression and cholesterol homeostasis. Cell Death Dis (2013) 0.92
In vitro quantification of specific microRNA using molecular beacons. Nucleic Acids Res (2011) 0.92
MicroRNA-277 modulates the neurodegeneration caused by Fragile X premutation rCGG repeats. PLoS Genet (2012) 0.92
Deregulation and therapeutic potential of microRNAs in arthritic diseases. Nat Rev Rheumatol (2015) 0.91
Role of microRNA-1 in human cancer and its therapeutic potentials. Biomed Res Int (2014) 0.90
Detection of simultaneous group effects in microRNA expression and related target gene sets. PLoS One (2012) 0.90
MiR-203 suppresses ZNF217 upregulation in colorectal cancer and its oncogenicity. PLoS One (2015) 0.90
Opposing actions of environmental enrichment and Alzheimer's disease on the expression of hippocampal microRNAs in mouse models. Transl Psychiatry (2013) 0.90
Identification of factors involved in target RNA-directed microRNA degradation. Nucleic Acids Res (2016) 0.89
Rbfox3 controls the biogenesis of a subset of microRNAs. Nat Struct Mol Biol (2014) 0.89
SIV replication is directly downregulated by four antiviral miRNAs. Retrovirology (2013) 0.89
Bias in ligation-based small RNA sequencing library construction is determined by adaptor and RNA structure. PLoS One (2015) 0.88
MicroRNA Regulation of Cholesterol Metabolism. Cholesterol (2012) 0.88
Chimeric tRNAs as tools to induce proteome damage and identify components of stress responses. Nucleic Acids Res (2009) 0.88
Oxidative stress mediated-alterations of the microRNA expression profile in mouse hippocampal neurons. Int J Mol Sci (2012) 0.88
MicroRNA-488 regulates zinc transporter SLC39A8/ZIP8 during pathogenesis of osteoarthritis. J Biomed Sci (2013) 0.88
The combination of transcriptomics and informatics identifies pathways targeted by miR-204 during neurogenesis and axon guidance. Nucleic Acids Res (2014) 0.88
Angiotensin receptor type 1 single nucleotide polymorphism 1166A/C is associated with malignant arrhythmias and altered circulating miR-155 levels in patients with chronic heart failure. J Card Fail (2012) 0.87
MicroRNA-1 prevents high-fat diet-induced endothelial permeability in apoE knock-out mice. Mol Cell Biochem (2013) 0.87
HDAC inhibitors target HDAC5, upregulate microRNA-125a-5p, and induce apoptosis in breast cancer cells. Mol Ther (2014) 0.87
c-Myc-regulated microRNAs modulate E2F1 expression. Nature (2005) 31.81
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol Cell (2007) 14.58
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism. Nature (2009) 13.28
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell (2009) 11.10
Widespread microRNA repression by Myc contributes to tumorigenesis. Nat Genet (2007) 10.78
Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster. Nat Genet (2006) 7.53
Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology (2006) 7.06
A hexanucleotide element directs microRNA nuclear import. Science (2007) 5.71
MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1. Proc Natl Acad Sci U S A (2008) 5.15
Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation. Proc Natl Acad Sci U S A (2009) 3.76
Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. J Clin Invest (2012) 3.14
P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis. Proc Natl Acad Sci U S A (2010) 2.49
miR-21: an androgen receptor-regulated microRNA that promotes hormone-dependent and hormone-independent prostate cancer growth. Cancer Res (2009) 2.39
Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. Genes Dev (2010) 2.37
MicroRNA miR-155 is a biomarker of early pancreatic neoplasia. Cancer Biol Ther (2009) 2.01
Cell-cell contact globally activates microRNA biogenesis. Proc Natl Acad Sci U S A (2009) 1.89
Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. Mol Cancer Ther (2011) 1.76
Epigenetic silencing of MicroRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer. Pancreatology (2009) 1.76
A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells. Cancer Biol Ther (2009) 1.61
Myc: Maestro of MicroRNAs. Genes Cancer (2010) 1.58
Circular reasoning: microRNAs and cell-cycle control. Trends Biochem Sci (2008) 1.41
Analysis of regulatory network topology reveals functionally distinct classes of microRNAs. Nucleic Acids Res (2008) 1.36
Functional integration of microRNAs into oncogenic and tumor suppressor pathways. Cell Cycle (2008) 1.33
Identification of miR-21 targets in breast cancer cells using a quantitative proteomic approach. Proteomics (2009) 1.28
Role of pri-miRNA tertiary structure in miR-17~92 miRNA biogenesis. RNA Biol (2011) 1.20
Noncoding RNAs and cancer. Cell (2013) 1.16
c-Myb oncoprotein is an essential target of the dleu2 tumor suppressor microRNA cluster. Cancer Biol Ther (2008) 1.15
Identifying targets of miR-143 using a SILAC-based proteomic approach. Mol Biosyst (2010) 1.12
PIPE-CLIP: a comprehensive online tool for CLIP-seq data analysis. Genome Biol (2014) 1.03
KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation. Blood (2011) 0.99
Abate and switch: miR-145 in stem cell differentiation. Cell (2009) 0.96
A novel source for miR-21 expression through the alternative polyadenylation of VMP1 gene transcripts. Nucleic Acids Res (2012) 0.93
Identification of miR-145 targets through an integrated omics analysis. Mol Biosyst (2014) 0.77
Quantification of global microRNA abundance by selective isotachophoresis. Anal Chem (2010) 0.76
When 19 is greater than 92. Elife (2013) 0.75
Seeing through the miRage of tissue complexity. Cell Cycle (2014) 0.75
MicroRNA-29 overexpression by adeno-associated virus suppresses fibrosis and restores muscle function in combination with micro-dystrophin. JCI Insight (2017) 0.75