|
1
|
STAT3 is a potential modulator of HIF-1-mediated VEGF expression in human renal carcinoma cells.
|
FASEB J
|
2005
|
2.60
|
|
2
|
Elevated levels of cholesterol-rich lipid rafts in cancer cells are correlated with apoptosis sensitivity induced by cholesterol-depleting agents.
|
Am J Pathol
|
2006
|
2.21
|
|
3
|
Simvastatin suppresses RANTES-mediated neutrophilia in polyinosinic-polycytidylic acid-induced pneumonia.
|
Eur Respir J
|
2012
|
2.10
|
|
4
|
Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma.
|
J Clin Invest
|
2008
|
1.35
|
|
5
|
Cooperation between integrin alpha5 and tetraspan TM4SF5 regulates VEGF-mediated angiogenic activity.
|
Blood
|
2008
|
1.12
|
|
6
|
Cholesterol depletion induces anoikis-like apoptosis via FAK down-regulation and caveolae internalization.
|
J Pathol
|
2009
|
1.05
|
|
7
|
STAT3-RANTES autocrine signaling is essential for tamoxifen resistance in human breast cancer cells.
|
Mol Cancer Res
|
2012
|
1.02
|
|
8
|
Cross-talk between TGFβ1 and EGFR signalling pathways induces TM4SF5 expression and epithelial-mesenchymal transition.
|
Biochem J
|
2012
|
1.01
|
|
9
|
Ethyl pyruvate has an anti-inflammatory effect by inhibiting ROS-dependent STAT signaling in activated microglia.
|
Free Radic Biol Med
|
2008
|
0.99
|
|
10
|
Interleukin-6 induces S100A9 expression in colonic epithelial cells through STAT3 activation in experimental ulcerative colitis.
|
PLoS One
|
2012
|
0.98
|
|
11
|
Erythroid cell-specific alpha-globin gene regulation by the CP2 transcription factor family.
|
Mol Cell Biol
|
2005
|
0.95
|
|
12
|
Hypoxia activates the cyclin D1 promoter via the Jak2/STAT5b pathway in breast cancer cells.
|
Exp Mol Med
|
2005
|
0.94
|
|
13
|
Anti-inflammatory and anti-allergic effects of Agrimonia pilosa Ledeb extract on murine cell lines and OVA-induced airway inflammation.
|
J Ethnopharmacol
|
2012
|
0.94
|
|
14
|
IFN-γ-induced BST2 mediates monocyte adhesion to human endothelial cells.
|
Cell Immunol
|
2010
|
0.93
|
|
15
|
8-hydroxydeoxyguanosine suppresses NO production and COX-2 activity via Rac1/STATs signaling in LPS-induced brain microglia.
|
Free Radic Biol Med
|
2006
|
0.93
|
|
16
|
Cell adhesion status-dependent histone acetylation is regulated through intracellular contractility-related signaling activities.
|
J Biol Chem
|
2005
|
0.93
|
|
17
|
Comparison of anti-oxidant activities of seventy herbs that have been used in Korean traditional medicine.
|
Nutr Res Pract
|
2008
|
0.91
|
|
18
|
Hypoxia activates the IGF-1 expression through STAT5b in human HepG2 cells.
|
Biochem Biophys Res Commun
|
2007
|
0.91
|
|
19
|
Phosphorylation and activation of STAT proteins by hypoxia in breast cancer cells.
|
Breast
|
2005
|
0.90
|
|
20
|
Methylsulfonylmethane suppresses breast cancer growth by down-regulating STAT3 and STAT5b pathways.
|
PLoS One
|
2012
|
0.90
|
|
21
|
Anti-adipogenic activity of compounds isolated from Idesia polycarpa on 3T3-L1 cells.
|
Bioorg Med Chem Lett
|
2013
|
0.90
|
|
22
|
Anti-inflammatory effects of 8-hydroxydeoxyguanosine in LPS-induced microglia activation: suppression of STAT3-mediated intercellular adhesion molecule-1 expression.
|
Exp Mol Med
|
2006
|
0.90
|
|
23
|
Relative antioxidant activities of quercetin and its structurally related substances and their effects on NF-κB/CRE/AP-1 signaling in murine macrophages.
|
Mol Cells
|
2013
|
0.88
|
|
24
|
Down-regulation of lipid raft-associated onco-proteins via cholesterol-dependent lipid raft internalization in docosahexaenoic acid-induced apoptosis.
|
Biochim Biophys Acta
|
2013
|
0.87
|
|
25
|
Benzo[a]pyrene-induced DNA damage and p53 modulation in human hepatoma HepG2 cells for the identification of potential biomarkers for PAH monitoring and risk assessment.
|
Toxicol Lett
|
2006
|
0.85
|
|
26
|
Antagonistic regulation of transmembrane 4 L6 family member 5 attenuates fibrotic phenotypes in CCl(4) -treated mice.
|
FEBS J
|
2012
|
0.85
|
|
27
|
Sophoraflavanone G induces apoptosis of human cancer cells by targeting upstream signals of STATs.
|
Biochem Pharmacol
|
2013
|
0.85
|
|
28
|
Enhancement of hypoxia-induced apoptosis of human breast cancer cells via STAT5b by momilactone B.
|
Int J Oncol
|
2008
|
0.85
|
|
29
|
Streptochlorin suppresses allergic dermatitis and mast cell activation via regulation of Lyn/Fyn and Syk signaling pathways in cellular and mouse models.
|
PLoS One
|
2013
|
0.85
|
|
30
|
Corynoxeine isolated from the hook of Uncaria rhynchophylla inhibits rat aortic vascular smooth muscle cell proliferation through the blocking of extracellular signal regulated kinase 1/2 phosphorylation.
|
Biol Pharm Bull
|
2008
|
0.85
|
|
31
|
Hypoxia activates signal transducers and activators of transcription 5 (STAT5) and increases its binding activity to the GAS element in mammary epithelial cells.
|
Exp Mol Med
|
2003
|
0.84
|
|
32
|
CADPE suppresses cyclin D1 expression in hepatocellular carcinoma by blocking IL-6-induced STAT3 activation.
|
Anticancer Res
|
2010
|
0.84
|
|
33
|
Epigenetic regulation of integrin-linked kinase expression depending on adhesion of gastric carcinoma cells.
|
Am J Physiol Cell Physiol
|
2006
|
0.83
|
|
34
|
Lipid raft modulation by Rp1 reverses multidrug resistance via inactivating MDR-1 and Src inhibition.
|
Biochem Pharmacol
|
2013
|
0.82
|
|
35
|
8-oxo-7,8-dihydroguanosine triphosphate(8-oxoGTP) down-regulates respiratory burst of neutrophils by antagonizing GTP toward Rac, a small GTP binding protein.
|
Free Radic Res
|
2007
|
0.82
|
|
36
|
Hemin inhibits cyclin D1 and IGF-1 expression via STAT5b under hypoxia in ERalpha-negative MDA-MB 231 breast cancer cells.
|
Int J Oncol
|
2010
|
0.82
|
|
37
|
Ca2+ signaling induced by sphingosine 1-phosphate and lysophosphatidic acid in mouse B cells.
|
Mol Cells
|
2010
|
0.81
|
|
38
|
Comparison of the antioxidant activities of nine different fruits in human plasma.
|
J Med Food
|
2005
|
0.81
|
|
39
|
Integrin signaling and cell spreading mediated by phorbol 12-myristate 13-acetate treatment.
|
J Cell Biochem
|
2006
|
0.81
|
|
40
|
HIF-1 is induced via EGFR activation and mediates resistance to anoikis-like cell death under lipid rafts/caveolae-disrupting stress.
|
Carcinogenesis
|
2009
|
0.81
|
|
41
|
Anti-inflammatory effects of 8-hydroxy-2'-deoxyguanosine on lipopolysaccharide-induced inflammation via Rac suppression in Balb/c mice.
|
Free Radic Biol Med
|
2007
|
0.81
|
|
42
|
Molecular Targeted Therapy for Hepatocellular Carcinoma: Present Status and Future Directions.
|
Biol Pharm Bull
|
2015
|
0.80
|
|
43
|
Neopterin, a marker of immune response, and 8-hydroxy-2'-deoxyguanosine, a marker of oxidative stress, correlate at high age as determined by automated simultaneous high-performance liquid chromatography analysis of human urine.
|
Anal Biochem
|
2008
|
0.80
|
|
44
|
Inhibitory effect of 8-oxo-7,8-dihydro-2'-deoxyguanosine on the growth of KG-1 myelosarcoma in Balb/c nude mice.
|
Leuk Res
|
2006
|
0.80
|
|
45
|
Inhibition of Rac and Rac-linked functions by 8-oxo-2'-deoxyguanosine in murine macrophages.
|
Free Radic Res
|
2009
|
0.80
|
|
46
|
Signal transducer and activator of transcription 3 (Stat3) contributes to T-cell homeostasis by regulating pro-survival Bcl-2 family genes.
|
Immunology
|
2013
|
0.79
|
|
47
|
Inhibition of double-stranded RNA-induced inducible nitric oxide synthase expression by fraxinellone and sauchinone in murine microglia.
|
Biol Pharm Bull
|
2009
|
0.79
|
|
48
|
Zeolite 4A, a synthetic silicate, suppresses melanogenesis through the degradation of microphthalmia-associated transcription factor by extracellular signal-regulated kinase activation in B16F10 melanoma cells.
|
Biol Pharm Bull
|
2010
|
0.79
|
|
49
|
Developmental retardation, microcephaly, and peptiduria in mice without aminopeptidase P1.
|
Biochem Biophys Res Commun
|
2012
|
0.78
|
|
50
|
MutY is down-regulated by oxidative stress in E. coli.
|
Free Radic Res
|
2003
|
0.78
|
|
51
|
Detection and identification of human papillomavirus types isolated from Korean patients with flat warts.
|
Microbiol Immunol
|
2005
|
0.78
|
|
52
|
cAMP signalling decreases p300 protein levels by promoting its ubiquitin/proteasome dependent degradation via Epac and p38 MAPK in lung cancer cells.
|
FEBS Lett
|
2013
|
0.78
|
|
53
|
Hypoxia upregulates Hsp90α expression via STAT5b in cancer cells.
|
Int J Oncol
|
2012
|
0.77
|
|
54
|
Simvastatin acts as an inhibitor of interferon gamma-induced cycloxygenase-2 expression in human THP-1 cells, but not in murine RAW264.7 cells.
|
Biocell
|
2009
|
0.77
|
|
55
|
Signal transducers and activators of transcription 3-induced metastatic potential in gastric cancer cells is enhanced by glycogen synthase kinase-3β.
|
APMIS
|
2015
|
0.77
|
|
56
|
Accessibility control of TCR Vγ region by STAT5.
|
Int Immunol
|
2010
|
0.76
|
|
57
|
MyD88-dependent Toll-like receptor signaling is required for murine macrophages response to IS2.
|
Int Immunopharmacol
|
2011
|
0.76
|
|
58
|
Anti-dermatitis effects of oak wood vinegar on the DNCB-induced contact hypersensitivity via STAT3 suppression.
|
J Ethnopharmacol
|
2011
|
0.76
|
|
59
|
An activin A/BMP2 chimera, AB204, displays bone-healing properties superior to those of BMP2.
|
J Bone Miner Res
|
2014
|
0.75
|
|
60
|
Anti-asthmatic activities of an ethanol extract of Aster yomena in an ovalbumin-induced murine asthma model.
|
J Med Food
|
2014
|
0.75
|
|
61
|
CK20 expression enhances the invasiveness of tamoxifen-resistant MCF-7 cells.
|
Anticancer Res
|
2012
|
0.75
|
|
62
|
Seeding of dendritic epidermal T cells in the neonatal skin is reduced in 129 strain of mice.
|
Immunol Lett
|
2002
|
0.75
|
|
63
|
8-Oxo-2'-deoxyguanosine ameliorates UVB-induced skin damage in hairless mice by scavenging reactive oxygen species and inhibiting MMP expression.
|
J Dermatol Sci
|
2013
|
0.75
|
|
64
|
[Accessibility control of the TCR gamma locus by the IL-7 receptor].
|
Tanpakushitsu Kakusan Koso
|
2002
|
0.75
|