Published in Biochim Biophys Acta on April 14, 2007
Phosphatidic acid phosphatase, a key enzyme in the regulation of lipid synthesis. J Biol Chem (2008) 1.76
An unconventional diacylglycerol kinase that regulates phospholipid synthesis and nuclear membrane growth. J Biol Chem (2008) 1.44
Diacylglycerol kinase regulates tyrosinase expression and function in human melanocytes. J Invest Dermatol (2012) 1.43
Diacylglycerol kinases in immune cell function and self-tolerance. Immunol Rev (2008) 1.28
Characterization of the yeast DGK1-encoded CTP-dependent diacylglycerol kinase. J Biol Chem (2008) 1.22
Synergistic control of T cell development and tumor suppression by diacylglycerol kinase alpha and zeta. Proc Natl Acad Sci U S A (2008) 1.22
Mammalian diacylglycerol kinases: molecular interactions and biological functions of selected isoforms. Biochim Biophys Acta (2009) 1.17
Diacylglycerol kinase α is a critical signaling node and novel therapeutic target in glioblastoma and other cancers. Cancer Discov (2013) 1.16
Phosphatidic acid signaling regulation of Ras superfamily of small guanosine triphosphatases. Biochim Biophys Acta (2009) 1.16
Phosphatidate phosphatase, a key regulator of lipid homeostasis. Biochim Biophys Acta (2012) 1.13
Diacylglycerol kinase alpha mediates HGF-induced Rac activation and membrane ruffling by regulating atypical PKC and RhoGDI. Proc Natl Acad Sci U S A (2010) 1.10
Mechanotransduction and the regulation of mTORC1 signaling in skeletal muscle. Int J Biochem Cell Biol (2011) 1.10
Diacylglycerol kinase epsilon is selective for both acyl chains of phosphatidic acid or diacylglycerol. J Biol Chem (2009) 1.10
An extended set of PRDM1/BLIMP1 target genes links binding motif type to dynamic repression. Nucleic Acids Res (2010) 1.07
Analysis of the Staphylococcus aureus DgkB structure reveals a common catalytic mechanism for the soluble diacylglycerol kinases. Structure (2008) 1.06
Diacylglycerol kinase eta augments C-Raf activity and B-Raf/C-Raf heterodimerization. J Biol Chem (2009) 1.03
Phospholipase D in the Golgi apparatus. Biochim Biophys Acta (2009) 1.00
Diacylglycerol kinases as sources of phosphatidic acid. Biochim Biophys Acta (2009) 0.99
Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes. Mol Biol Cell (2013) 0.99
Synaptic removal of diacylglycerol by DGKzeta and PSD-95 regulates dendritic spine maintenance. EMBO J (2009) 0.98
Receptor signaling in immune cell development and function. Immunol Res (2011) 0.98
DGKι regulates presynaptic release during mGluR-dependent LTD. EMBO J (2010) 0.94
Zinc binding drives sheet formation by the SAM domain of diacylglycerol kinase δ. Biochemistry (2010) 0.87
Regulation of Lipid Signaling by Diacylglycerol Kinases during T Cell Development and Function. Front Immunol (2013) 0.87
Diacylglycerol kinase beta promotes dendritic outgrowth and spine maturation in developing hippocampal neurons. BMC Neurosci (2009) 0.86
Diacylglycerol kinase β knockout mice exhibit attention-deficit behavior and an abnormal response on methylphenidate-induced hyperactivity. PLoS One (2012) 0.85
Role of diacylglycerol kinases in T cell development and function. Crit Rev Immunol (2013) 0.85
Distinct expression and localization of the type II diacylglycerol kinase isozymes δ, η and κ in the mouse reproductive organs. BMC Dev Biol (2015) 0.84
The rice diacylglycerol kinase family: functional analysis using transient RNA interference. Front Plant Sci (2012) 0.84
cAMP-stimulated transcription of DGKθ requires steroidogenic factor 1 and sterol regulatory element binding protein 1. J Lipid Res (2013) 0.83
A novel diacylglycerol kinase α-selective inhibitor, CU-3, induces cancer cell apoptosis and enhances immune response. J Lipid Res (2016) 0.82
Diacylglycerol kinase as a possible therapeutic target for neuronal diseases. J Biomed Sci (2014) 0.82
Dual regulation of RA-RhoGAP activity by phosphatidic acid and Rap1 during neurite outgrowth. J Biol Chem (2010) 0.82
Diacylglycerol kinase δ phosphorylates phosphatidylcholine-specific phospholipase C-dependent, palmitic acid-containing diacylglycerol species in response to high glucose levels. J Biol Chem (2014) 0.82
Inhibition of lipid signaling enzyme diacylglycerol kinase epsilon attenuates mutant huntingtin toxicity. J Biol Chem (2012) 0.81
Knockdown of diacylglycerol kinase delta inhibits adipocyte differentiation and alters lipid synthesis. Obesity (Silver Spring) (2013) 0.81
Diacylglycerol kinase-dependent formation of phosphatidic acid molecular species during interleukin-2 activation in CTLL-2 T-lymphocytes. FEBS Open Bio (2012) 0.80
DAG tales: the multiple faces of diacylglycerol--stereochemistry, metabolism, and signaling. Cell Mol Life Sci (2015) 0.80
Phospholipid signaling during stramenopile development. Plant Signal Behav (2008) 0.80
Expression and localization of type II diacylglycerol kinase isozymes δ and η in the developing mouse brain. J Histochem Cytochem (2014) 0.80
Altered expression of diacylglycerol kinase isozymes in regenerating liver. J Histochem Cytochem (2011) 0.79
Phosphorylation of Dgk1 Diacylglycerol Kinase by Casein Kinase II Regulates Phosphatidic Acid Production in Saccharomyces cerevisiae. J Biol Chem (2016) 0.79
Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases. Biochem Biophys Res Commun (2012) 0.79
c-Abl tyrosine kinase regulates serum-induced nuclear export of diacylglycerol kinase α by phosphorylation at Tyr-218. J Biol Chem (2011) 0.79
Molecular determinants for interfacial binding and conformational change in a soluble diacylglycerol kinase. J Biol Chem (2008) 0.79
Diacylglycerol kinase θ couples farnesoid X receptor-dependent bile acid signalling to Akt activation and glucose homoeostasis in hepatocytes. Biochem J (2013) 0.79
Diacylglycerol kinase inhibitor R59022 attenuates conjugated linoleic acid-mediated inflammation in human adipocytes. J Lipid Res (2012) 0.78
Distinct expression and localization of diacylglycerol kinase isozymes in rat retina. J Histochem Cytochem (2013) 0.78
Overexpression of diacylglycerol kinase η enhances Gαq-coupled G protein-coupled receptor signaling. Mol Pharmacol (2014) 0.78
The Pleckstrin Homology Domain of Diacylglycerol Kinase η Strongly and Selectively Binds to Phosphatidylinositol 4,5-Bisphosphate. J Biol Chem (2016) 0.78
Signaling cascade of diacylglycerol kinase β in the pituitary intermediate lobe: dopamine D2 receptor/phospholipase Cβ4/diacylglycerol kinase β/protein kinase Cα. J Histochem Cytochem (2010) 0.78
Involvement of diacylglycerol kinase γ in modulation of iNOS synthesis in Golgi apparatus of vascular endothelial cells. Naunyn Schmiedebergs Arch Pharmacol (2012) 0.78
Differential regulation of diacylglycerol kinase isoform in human failing hearts. J Cardiothorac Surg (2011) 0.77
Inhibition of ROS and upregulation of inflammatory cytokines by FoxO3a promotes survival against Salmonella typhimurium. Nat Commun (2016) 0.76
NMDA receptor-mediated Ca(2+) influx triggers nucleocytoplasmic translocation of diacylglycerol kinase ζ under oxygen-glucose deprivation conditions, an in vitro model of ischemia, in rat hippocampal slices. Histochem Cell Biol (2012) 0.76
Diacylglycerol Kinase-ε: Properties and Biological Roles. Front Cell Dev Biol (2016) 0.76
Diacylglycerol Kinases as Emerging Potential Drug Targets for a Variety of Diseases: An Update. Front Cell Dev Biol (2016) 0.76
Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells. Biochim Biophys Acta (2013) 0.76
EF-hand motifs of diacylglycerol kinase α interact intra-molecularly with its C1 domains. FEBS Open Bio (2014) 0.76
Diacylglycerol Kinases in T Cell Tolerance and Effector Function. Front Cell Dev Biol (2016) 0.76
Transcription factor Reb1p regulates DGK1-encoded diacylglycerol kinase and lipid metabolism in Saccharomyces cerevisiae. J Biol Chem (2013) 0.76
Cloning and Characterization of Novel Testis-Specific Diacylglycerol Kinase η Splice Variants 3 and 4. PLoS One (2016) 0.75
Arachidonoyl-Specific Diacylglycerol Kinase ε and the Endoplasmic Reticulum. Front Cell Dev Biol (2016) 0.75
Diacylglycerol Kinase Inhibition and Vascular Function. Curr Enzym Inhib (2009) 0.75
Diacylglycerol Kinases: Shaping Diacylglycerol and Phosphatidic Acid Gradients to Control Cell Polarity. Front Cell Dev Biol (2016) 0.75
Diacylglycerol kinase ε deficiency preserves glucose tolerance and modulates lipid metabolism in obese mice. J Lipid Res (2017) 0.75
Diacylglycerol Kinases in the Coordination of Synaptic Plasticity. Front Cell Dev Biol (2016) 0.75
Expressional profile of the diacylglycerol kinase eta gene DGKH. Eur Arch Psychiatry Clin Neurosci (2016) 0.75
Activation of conventional and novel protein kinase C isozymes by different diacylglycerol molecular species. Biochem Biophys Rep (2016) 0.75
R59949, a diacylglycerol kinase inhibitor, inhibits inducible nitric oxide production through decreasing transplasmalemmal L-arginine uptake in vascular smooth muscle cells. Naunyn Schmiedebergs Arch Pharmacol (2016) 0.75
Diacylglycerol kinase ζ generates dipalmitoyl-phosphatidic acid species during neuroblastoma cell differentiation. Biochem Biophys Rep (2016) 0.75
Cellular expression and localization of DGKζ-interacting NAP1-like proteins in the brain and functional implications under hypoxic stress. Histochem Cell Biol (2014) 0.75
Molecular machinery for non-vesicular trafficking of ceramide. Nature (2003) 5.19
Prognostic stratification of patients with vasospastic angina: a comprehensive clinical risk score developed by the Japanese Coronary Spasm Association. J Am Coll Cardiol (2013) 2.51
The Great East Japan Earthquake Disaster and cardiovascular diseases. Eur Heart J (2012) 2.32
Role of Rho-kinase in the pathogenesis of coronary hyperconstricting responses induced by drug-eluting stents in pigs in vivo. J Am Coll Cardiol (2009) 2.10
A novel pit pattern identifies the precursor of colorectal cancer derived from sessile serrated adenoma. Am J Gastroenterol (2012) 2.06
Lysophosphatidic acid induces neointima formation through PPARgamma activation. J Exp Med (2004) 1.86
Extracting the full potential of single-walled carbon nanotubes as durable supercapacitor electrodes operable at 4 V with high power and energy density. Adv Mater (2010) 1.83
A black body absorber from vertically aligned single-walled carbon nanotubes. Proc Natl Acad Sci U S A (2009) 1.74
Right ventricular reverse remodelling after balloon pulmonary angioplasty. Eur Respir J (2014) 1.73
DNA methylation and microRNA dysregulation in cancer. Mol Oncol (2012) 1.69
Clinical implications of provocation tests for coronary artery spasm: safety, arrhythmic complications, and prognostic impact: multicentre registry study of the Japanese Coronary Spasm Association. Eur Heart J (2012) 1.68
Importance of dual induction tests for coronary vasospasm and ventricular fibrillation in patients surviving out-of-hospital cardiac arrest. Circ J (2009) 1.66
Enhanced Rho-kinase activity in circulating neutrophils of patients with vasospastic angina: a possible biomarker for diagnosis and disease activity assessment. J Am Coll Cardiol (2011) 1.62
Prognostic effects of calcium channel blockers in patients with vasospastic angina--a meta-analysis. Circ J (2010) 1.61
Plasma cyclophilin A is a novel biomarker for coronary artery disease. Circ J (2012) 1.59
Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect. Carcinogenesis (2010) 1.52
Admission hyperglycemia is an independent predictor of acute kidney injury in patients with acute myocardial infarction. Circ J (2014) 1.49
Impact of Elevated D-Dimer on Diagnosis of Acute Aortic Dissection With Isolated Neurological Symptoms in Ischemic Stroke. Circ J (2015) 1.46
Risk Stratification of Acute Kidney Injury Using the Blood Urea Nitrogen/Creatinine Ratio in Patients With Acute Decompensated Heart Failure. Circ J (2015) 1.46
CERT mediates intermembrane transfer of various molecular species of ceramides. J Biol Chem (2004) 1.44
Effects of voglibose and nateglinide on glycemic status and coronary atherosclerosis in early-stage diabetic patients. Circ J (2012) 1.44
Emergency care of acute myocardial infarction and the great East Japan earthquake disaster. Circ J (2014) 1.43
High-Intensity Plaques on Noncontrast T1-Weighted Imaging as a Predictor of Periprocedural Myocardial Injury. JACC Cardiovasc Imaging (2014) 1.42
Heparin-binding EGF-like growth factor is a promising target for ovarian cancer therapy. Cancer Res (2004) 1.41
Genome-wide profiling of chromatin signatures reveals epigenetic regulation of MicroRNA genes in colorectal cancer. Cancer Res (2011) 1.40
Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARgamma, and inhibitors of autotaxin. J Med Chem (2005) 1.40
Rationale and Design of the Double-Blind, Randomized, Placebo-Controlled Multicenter Trial on Efficacy of Early Initiation of Eplerenone Treatment in Patients with Acute Heart Failure (EARLIER). Cardiovasc Drugs Ther (2015) 1.39
Involvement of rho-kinase activation in the pathogenesis of coronary hyperconstricting responses induced by drug-eluting stents in patients with coronary artery disease. Circ J (2012) 1.39
Association of Adventitial Vasa Vasorum and Inflammation With Coronary Hyperconstriction After Drug-Eluting Stent Implantation in Pigs In Vivo. Circ J (2015) 1.39
Prognostic Impacts of Metabolic Syndrome in Patients With Chronic Heart Failure - A Multicenter Prospective Cohort Study. Circ J (2016) 1.39
Congenitally Corrected Transposition of the Great Arteries and Situs Inversus in an Octogenarian With Systemic Right Ventricular Failure. Int Heart J (2016) 1.38
Double-blind and placebo-controlled study of the effectiveness and safety of extracorporeal cardiac shock wave therapy for severe angina pectoris. Circ J (2010) 1.36
Trends in acute myocardial infarction incidence and mortality over 30 years in Japan: report from the MIYAGI-AMI Registry Study. Circ J (2009) 1.36
IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype. Carcinogenesis (2009) 1.34
Prospective randomized controlled study of gastric emptying assessed by (13)C-acetate breath test after pylorus-preserving pancreaticoduodenectomy: comparison between antecolic and vertical retrocolic duodenojejunostomy. J Hepatobiliary Pancreat Surg (2008) 1.29
Regulation of enzyme localization by polymerization: polymer formation by the SAM domain of diacylglycerol kinase delta1. Structure (2008) 1.28
Fish oil and omega-3 fatty acids in cardiovascular disease: do they really work? Eur Heart J (2011) 1.28
Different residues mediate recognition of 1-O-oleyllysophosphatidic acid and rosiglitazone in the ligand binding domain of peroxisome proliferator-activated receptor gamma. J Biol Chem (2005) 1.27
Identification and characterization of two splice variants of human diacylglycerol kinase eta. J Biol Chem (2003) 1.25
Identification and characterization of a novel human type II diacylglycerol kinase, DGK kappa. J Biol Chem (2005) 1.25
Highly sensitive in vitro methods for detection of residual undifferentiated cells in retinal pigment epithelial cells derived from human iPS cells. PLoS One (2012) 1.24
Alternative splicing of the human diacylglycerol kinase delta gene generates two isoforms differing in their expression patterns and in regulatory functions. J Biol Chem (2002) 1.19
Molecular dissection of premalignant colorectal lesions reveals early onset of the CpG island methylator phenotype. Am J Pathol (2012) 1.17
Clinical characteristics and long-term prognosis of vasospastic angina patients who survived out-of-hospital cardiac arrest: multicenter registry study of the Japanese Coronary Spasm Association. Circ Arrhythm Electrophysiol (2011) 1.16
Hereditary sensory neuropathy type 1 mutations confer dominant negative effects on serine palmitoyltransferase, critical for sphingolipid synthesis. J Clin Invest (2002) 1.14
Diacylglycerol kinase delta suppresses ER-to-Golgi traffic via its SAM and PH domains. Mol Biol Cell (2002) 1.08
Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer. Breast Cancer Res Treat (2009) 1.07
Favourable clinical outcome in patients with cardiogenic shock due to fulminant myocarditis supported by percutaneous extracorporeal membrane oxygenation. Eur Heart J (2005) 1.06
Diacylglycerol kinase eta augments C-Raf activity and B-Raf/C-Raf heterodimerization. J Biol Chem (2009) 1.03
Diacylglycerol kinase alpha suppresses tumor necrosis factor-alpha-induced apoptosis of human melanoma cells through NF-kappaB activation. Biochim Biophys Acta (2007) 1.01
Differential localization of lipid phosphate phosphatases 1 and 3 to cell surface subdomains in polarized MDCK cells. FEBS Lett (2003) 1.01
Stable knock-down of the sphingosine 1-phosphate receptor S1P1 influences multiple functions of human endothelial cells. Arterioscler Thromb Vasc Biol (2004) 1.01
Effect of the Great East Japan Earthquake on cardiovascular diseases--report from the 10 hospitals in the disaster area. Circ J (2013) 1.00
Methylation of a panel of microRNA genes is a novel biomarker for detection of bladder cancer. Eur Urol (2012) 1.00
Phorbol ester-regulated oligomerization of diacylglycerol kinase delta linked to its phosphorylation and translocation. J Biol Chem (2002) 1.00
Diacylglycerol kinases as emerging potential drug targets for a variety of diseases. Curr Drug Targets (2008) 0.99
Cardiac shock wave therapy ameliorates left ventricular remodeling after myocardial ischemia-reperfusion injury in pigs in vivo. Coron Artery Dis (2010) 0.99
Surgical strategy for hepatocellular carcinoma patients with portal vein tumor thrombus based on prognostic factors. J Gastrointest Surg (2009) 0.99
Effect of nucleos(t)ide analogue therapy on hepatocarcinogenesis in chronic hepatitis B patients: a propensity score analysis. J Hepatol (2012) 0.98
Differences in long-term outcome and prognostic factors according to viral status in patients with hepatocellular carcinoma treated by surgery. J Gastrointest Surg (2007) 0.98
Comparison of seven prognostic staging systems in patients who undergo hepatectomy for hepatocellular carcinoma. Hepatogastroenterology (2007) 0.98
Pathological and clinical impact of neoadjuvant chemoradiotherapy using full-dose gemcitabine and concurrent radiation for resectable pancreatic cancer. J Hepatobiliary Pancreat Sci (2013) 0.97
Exploring advantages of diverse carbon nanotube forests with tailored structures synthesized by supergrowth from engineered catalysts. ACS Nano (2009) 0.96
Initial experience using Excimer laser for the extraction of chronically implanted pacemaker and implantable cardioverter defibrillator leads in Japanese patients. J Cardiol (2013) 0.95
Segmentectomy for reactive lymphoid hyperplasia of the liver: Report of a case. Surg Today (2006) 0.95
Hepatic resection is justified for elderly patients with hepatocellular carcinoma. World J Surg (2008) 0.95
Aberrant methylation of RASGRF1 is associated with an epigenetic field defect and increased risk of gastric cancer. Cancer Prev Res (Phila) (2012) 0.94
Outcome of surgical treatment of hilar cholangiocarcinoma. J Gastrointest Surg (2007) 0.94
DNA methylation of interferon regulatory factors in gastric cancer and noncancerous gastric mucosae. Cancer Sci (2010) 0.93
Optimal lysophosphatidic acid-induced DNA synthesis and cell migration but not survival require intact autophosphorylation sites of the epidermal growth factor receptor. J Biol Chem (2004) 0.93
PCA-1/ALKBH3 contributes to pancreatic cancer by supporting apoptotic resistance and angiogenesis. Cancer Res (2012) 0.93
Tumorigenicity studies for human pluripotent stem cell-derived products. Biol Pharm Bull (2013) 0.92
Role of subsurface diffusion and Ostwald ripening in catalyst formation for single-walled carbon nanotube forest growth. J Am Chem Soc (2012) 0.92
Delayed appearance of coronary artery perforation following cutting balloon angioplasty. Catheter Cardiovasc Interv (2002) 0.91
Efficacy of additional radiofrequency applications for spontaneous dissociated pulmonary vein activity after pulmonary vein isolation in patients with paroxysmal atrial fibrillation. J Cardiovasc Electrophysiol (2013) 0.90
Three cases of acute myocardial infarction due to coronary embolism: treatment using a thrombus aspiration device. Jpn Heart J (2004) 0.90
Myocardial ischemia: current concepts and future perspectives. J Cardiol (2008) 0.90
Diacylglycerol kinase alpha enhances protein kinase Czeta-dependent phosphorylation at Ser311 of p65/RelA subunit of nuclear factor-kappaB. FEBS Lett (2009) 0.89
Regulation of immature protein dynamics in the endoplasmic reticulum. J Biol Chem (2004) 0.89
Formation process of cyclodextrin necklace-analysis of hydrogen bonding on a molecular level. J Am Chem Soc (2003) 0.89
Two-year clinical, angiographic, and serial optical coherence tomographic follow-up after implantation of an everolimus-eluting bioresorbable scaffold and an everolimus-eluting metallic stent: insights from the randomised ABSORB Japan trial. EuroIntervention (2016) 0.89
Lipid phosphate phosphatases 1 and 3 are localized in distinct lipid rafts. J Biochem (2006) 0.88
Nuclear expression of thioredoxin-1 in the invasion front is associated with outcome in patients with gallbladder carcinoma. HPB (Oxford) (2012) 0.88