Published in Mol Oncol on August 10, 2012
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DNA methylation data analysis and its application to cancer research. Epigenomics (2013) 1.14
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DNA methylation, microRNAs, and their crosstalk as potential biomarkers in hepatocellular carcinoma. World J Gastroenterol (2014) 0.99
Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors. Genome Biol (2013) 0.97
MicroRNA polymorphisms and environmental smoke exposure as risk factors for oesophageal squamous cell carcinoma. PLoS One (2013) 0.91
Extracellular RNA mediates and marks cancer progression. Semin Cancer Biol (2014) 0.90
Downregulation of miR-452 promotes stem-like traits and tumorigenicity of gliomas. Clin Cancer Res (2013) 0.89
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Age-dependent increase in miRNA-34a expression in the posterior pole of the mouse eye. Mol Vis (2014) 0.89
KITENIN-targeting microRNA-124 suppresses colorectal cancer cell motility and tumorigenesis. Mol Ther (2014) 0.89
Increased expression of microRNA-150 is associated with poor prognosis in non-small cell lung cancer. Int J Clin Exp Pathol (2015) 0.87
Genome-wide DNA methylome analysis reveals epigenetically dysregulated non-coding RNAs in human breast cancer. Sci Rep (2015) 0.86
Utility of Serum miR-125b as a Diagnostic and Prognostic Indicator and Its Alliance with a Panel of Tumor Suppressor Genes in Epithelial Ovarian Cancer. PLoS One (2016) 0.85
Reactivation of epigenetically silenced miR-124 reverses the epithelial-to-mesenchymal transition and inhibits invasion in endometrial cancer cells via the direct repression of IQGAP1 expression. Oncotarget (2016) 0.85
MicroRNA-217 regulates WASF3 expression and suppresses tumor growth and metastasis in osteosarcoma. PLoS One (2014) 0.85
DNA methylation, early life environment, and health outcomes. Pediatr Res (2015) 0.84
MicroRNA-184 Modulates Doxorubicin Resistance in Osteosarcoma Cells by Targeting BCL2L1. Med Sci Monit (2016) 0.82
Interleukin-6 mediated upregulation of CYP1B1 and CYP2E1 in colorectal cancer involves DNA methylation, miR27b and STAT3. Br J Cancer (2014) 0.82
Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk. J Gastroenterol (2013) 0.82
Downregulation of IFNG in CD4(+) T cells in lung cancer through hypermethylation: a possible mechanism of tumor-induced immunosuppression. PLoS One (2013) 0.82
Decreased fructose-1,6-bisphosphatase-2 expression promotes glycolysis and growth in gastric cancer cells. Mol Cancer (2013) 0.81
MiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators. Oncotarget (2015) 0.81
MicroRNA-212 functions as an epigenetic-silenced tumor suppressor involving in tumor metastasis and invasion of gastric cancer through down-regulating PXN expression. Am J Cancer Res (2015) 0.80
Suberoylanilide hydroxamic acid inhibits growth of head and neck cancer cell lines by reactivation of tumor suppressor microRNAs. Oral Oncol (2016) 0.80
MicroRNA expression patterns and signalling pathways in the development and progression of childhood solid tumours. Mol Cancer (2017) 0.79
Recent progress in the genetics and epigenetics of paraoxonase: why it is relevant to children's environmental health. Curr Opin Pediatr (2015) 0.79
Genome-Wide DNA Methylation Patterns of Bovine Blastocysts Developed In Vivo from Embryos Completed Different Stages of Development In Vitro. PLoS One (2015) 0.79
Combining position weight matrices and document-term matrix for efficient extraction of associations of methylated genes and diseases from free text. PLoS One (2013) 0.79
The mechanistic role of DNA methylation in myeloid leukemogenesis. Leukemia (2014) 0.79
Downregulation of microRNA-362-3p and microRNA-329 promotes tumor progression in human breast cancer. Cell Death Differ (2015) 0.79
Differential analysis of biological networks. BMC Bioinformatics (2015) 0.79
Reversal of microRNA-150 silencing disadvantages crizotinib-resistant NPM-ALK(+) cell growth. J Clin Invest (2015) 0.78
miR-29a activates Hes1 by targeting Nfia in esophageal carcinoma cell line TE-1. Oncol Lett (2014) 0.78
DNA Methylation Modulates Nociceptive Sensitization after Incision. PLoS One (2015) 0.78
TAGLN expression is upregulated in NF1-associated malignant peripheral nerve sheath tumors by hypomethylation in its promoter and subpromoter regions. Oncol Rep (2014) 0.77
Integrative modeling of multi-platform genomic data under the framework of mediation analysis. Stat Med (2014) 0.77
Hsa-miR-15a and Hsa-miR-16-1 expression is not related to proliferation centers abundance and other prognostic factors in chronic lymphocytic leukemia. Biomed Res Int (2013) 0.77
MiRNA-15a inhibits proliferation, migration and invasion by targeting TNFAIP1 in human osteosarcoma cells. Int J Clin Exp Pathol (2015) 0.77
miR-196b Is Epigenetically Silenced during the Premalignant Stage of Lung Carcinogenesis. Cancer Res (2016) 0.77
A genomic screen for long noncoding RNA genes epigenetically silenced by aberrant DNA methylation in colorectal cancer. Sci Rep (2016) 0.77
Epigenetic Repression of miR-218 Promotes Esophageal Carcinogenesis by Targeting ROBO1. Int J Mol Sci (2015) 0.76
MicroRNA-148b Acts as a Tumor Suppressor in Cervical Cancer by Inducing G1/S-Phase Cell Cycle Arrest and Apoptosis in a Caspase-3-Dependent Manner. Med Sci Monit (2016) 0.75
Iodine-125 irradiation inhibits invasion of gastric cancer cells by reactivating microRNA-181c expression. Oncol Lett (2016) 0.75
VEGFA activates an epigenetic pathway upregulating ovarian cancer-initiating cells. EMBO Mol Med (2017) 0.75
Identification of circulating microRNAs during the liver neoplastic process in a murine model of hereditary tyrosinemia type 1. Sci Rep (2016) 0.75
A Circulating microRNA Signature Predicts Age-Based Development of Lymphoma. PLoS One (2017) 0.75
Differential DNA Methylation of MicroRNA Genes in Temporal Cortex from Alzheimer's Disease Individuals. Neural Plast (2016) 0.75
A Screen for Epigenetically Silenced microRNA Genes in Gastrointestinal Stromal Tumors. PLoS One (2015) 0.75
Clinical and biological significance of miR-23b and miR-193a in human hepatocellular carcinoma. Oncotarget (2016) 0.75
MiR-193b promoter methylation accurately detects prostate cancer in urine sediments and miR-34b/c or miR-129-2 promoter methylation define subsets of clinically aggressive tumors. Mol Cancer (2017) 0.75
Epigenetically altered miR-1247 functions as a tumor suppressor in pancreatic cancer. Oncotarget (2017) 0.75
Demethylation of the MIR145 promoter suppresses migration and invasion in breast cancer. Oncotarget (2017) 0.75
How to stomach an epigenetic insult: the gastric cancer epigenome. Nat Rev Gastroenterol Hepatol (2017) 0.75
The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors. J Clin Invest (2011) 4.41
Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res (2008) 3.81
Upregulation of miR-196a and HOTAIR drive malignant character in gastrointestinal stromal tumors. Cancer Res (2012) 2.45
A novel pit pattern identifies the precursor of colorectal cancer derived from sessile serrated adenoma. Am J Gastroenterol (2012) 2.06
Diacylglycerol kinases: why so many of them? Biochim Biophys Acta (2007) 1.85
Beneficial effects of pioglitazone on hypertensive cardiovascular injury are enhanced by combination with candesartan. Hypertension (2007) 1.68
Coronary microvascular dysfunction and diastolic load correlate with cardiac troponin T release measured by a highly sensitive assay in patients with nonischemic heart failure. J Am Coll Cardiol (2013) 1.59
Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B. Atherosclerosis (2011) 1.55
Aliskiren enhances protective effects of valsartan against type 2 diabetic nephropathy in mice. J Hypertens (2010) 1.52
Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors. Carcinogenesis (2007) 1.52
Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect. Carcinogenesis (2010) 1.52
Eplerenone potentiates protective effects of amlodipine against cardiovascular injury in salt-sensitive hypertensive rats. Hypertens Res (2011) 1.46
Gene expression profiling of human breast tissue samples using SAGE-Seq. Genome Res (2010) 1.41
Circulating thrombospondin-2 reflects disease severity and predicts outcome of heart failure with reduced ejection fraction. Circ J (2014) 1.41
Heparin-binding EGF-like growth factor is a promising target for ovarian cancer therapy. Cancer Res (2004) 1.41
Genome-wide profiling of chromatin signatures reveals epigenetic regulation of MicroRNA genes in colorectal cancer. Cancer Res (2011) 1.40
IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype. Carcinogenesis (2009) 1.34
Pentraxin 3 is a new inflammatory marker correlated with left ventricular diastolic dysfunction and heart failure with normal ejection fraction. J Am Coll Cardiol (2011) 1.32
Fusobacterium in colonic flora and molecular features of colorectal carcinoma. Cancer Res (2014) 1.30
Prospective randomized controlled study of gastric emptying assessed by (13)C-acetate breath test after pylorus-preserving pancreaticoduodenectomy: comparison between antecolic and vertical retrocolic duodenojejunostomy. J Hepatobiliary Pancreat Surg (2008) 1.29
Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma. J Gastroenterol (2008) 1.25
Identification and characterization of a novel human type II diacylglycerol kinase, DGK kappa. J Biol Chem (2005) 1.25
PRDM5 identified as a target of epigenetic silencing in colorectal and gastric cancer. Clin Cancer Res (2007) 1.21
Association of microRNA-31 with BRAF mutation, colorectal cancer survival and serrated pathway. Carcinogenesis (2013) 1.19
Gene amplification and overexpression of PRDM14 in breast cancers. Cancer Res (2007) 1.18
Molecular dissection of premalignant colorectal lesions reveals early onset of the CpG island methylator phenotype. Am J Pathol (2012) 1.17
Identification of SCN3B as a novel p53-inducible proapoptotic gene. Oncogene (2004) 1.16
Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer. Cancer Sci (2007) 1.14
A novel correlation between LINE-1 hypomethylation and the malignancy of gastrointestinal stromal tumors. Clin Cancer Res (2010) 1.14
Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics. Cell Stem Cell (2013) 1.14
Epigenetic patterns of embryonic and adult stem cells. Cell Cycle (2009) 1.13
Pioglitazone exerts protective effects against stroke in stroke-prone spontaneously hypertensive rats, independently of blood pressure. Stroke (2007) 1.11
Perindopril, a centrally active angiotensin-converting enzyme inhibitor, prevents cognitive impairment in mouse models of Alzheimer's disease. FASEB J (2011) 1.10
LINE-1 hypomethylation is associated with increased CpG island methylation in Helicobacter pylori-related enlarged-fold gastritis. Cancer Epidemiol Biomarkers Prev (2008) 1.08
Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer. Breast Cancer Res Treat (2009) 1.07
Diacylglycerol kinase eta augments C-Raf activity and B-Raf/C-Raf heterodimerization. J Biol Chem (2009) 1.03
Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma. Clin Cancer Res (2009) 1.03
CC chemokine receptor-2 deficiency attenuates oxidative stress and infarct size caused by myocardial ischemia-reperfusion in mice. Circ J (2006) 1.02
A novel method, digital genome scanning detects KRAS gene amplification in gastric cancers: involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth. BMC Cancer (2009) 1.02
Diacylglycerol kinase alpha suppresses tumor necrosis factor-alpha-induced apoptosis of human melanoma cells through NF-kappaB activation. Biochim Biophys Acta (2007) 1.01
Differential localization of lipid phosphate phosphatases 1 and 3 to cell surface subdomains in polarized MDCK cells. FEBS Lett (2003) 1.01
Methylation of a panel of microRNA genes is a novel biomarker for detection of bladder cancer. Eur Urol (2012) 1.00
Diacylglycerol kinases as emerging potential drug targets for a variety of diseases. Curr Drug Targets (2008) 0.99
Surgical strategy for hepatocellular carcinoma patients with portal vein tumor thrombus based on prognostic factors. J Gastrointest Surg (2009) 0.99
Differences in long-term outcome and prognostic factors according to viral status in patients with hepatocellular carcinoma treated by surgery. J Gastrointest Surg (2007) 0.98
Comparison of seven prognostic staging systems in patients who undergo hepatectomy for hepatocellular carcinoma. Hepatogastroenterology (2007) 0.98
Attenuation of brain damage and cognitive impairment by direct renin inhibition in mice with chronic cerebral hypoperfusion. Hypertension (2011) 0.97
Critical role of angiotensin II in excess salt-induced brain oxidative stress of stroke-prone spontaneously hypertensive rats. Stroke (2005) 0.97
Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma. Cancer Sci (2008) 0.95
Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancer. Carcinogenesis (2008) 0.95
Segmentectomy for reactive lymphoid hyperplasia of the liver: Report of a case. Surg Today (2006) 0.95
MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions. Int J Cancer (2014) 0.95
Hepatic resection is justified for elderly patients with hepatocellular carcinoma. World J Surg (2008) 0.95
Aberrant methylation of RASGRF1 is associated with an epigenetic field defect and increased risk of gastric cancer. Cancer Prev Res (Phila) (2012) 0.94
Outcome of surgical treatment of hilar cholangiocarcinoma. J Gastrointest Surg (2007) 0.94
DNA methylation of interferon regulatory factors in gastric cancer and noncancerous gastric mucosae. Cancer Sci (2010) 0.93
Novel mechanism of angiotensin II-induced cardiac injury in hypertensive rats: the critical role of ASK1 and VEGF. Hypertens Res (2011) 0.92
Apoptosis signal-regulating kinase-1 is involved in vascular endothelial and cardiac remodeling caused by nitric oxide deficiency. Hypertension (2007) 0.91
CLCA2, a target of the p53 family, negatively regulates cancer cell migration and invasion. Cancer Biol Ther (2012) 0.91
Microvascular coronary artery spasm presents distinctive clinical features with endothelial dysfunction as nonobstructive coronary artery disease. J Am Heart Assoc (2012) 0.89
Nuclear expression of thioredoxin-1 in the invasion front is associated with outcome in patients with gallbladder carcinoma. HPB (Oxford) (2012) 0.88
Identification of flotillin-2, a major protein on lipid rafts, as a novel target of p53 family members. Mol Cancer Res (2008) 0.88
Outcome of radical surgery for stage IV gallbladder carcinoma. J Hepatobiliary Pancreat Surg (2007) 0.87
Beneficial effects of combination of valsartan and amlodipine on salt-induced brain injury in hypertensive rats. J Pharmacol Exp Ther (2011) 0.87
Diacylglycerol kinase gamma serves as an upstream suppressor of Rac1 and lamellipodium formation. J Biol Chem (2004) 0.87
Risk factors for early death after liver resection in patients with solitary hepatocellular carcinoma. J Hepatobiliary Pancreat Surg (2005) 0.87
Diacylglycerol kinase delta associates with receptor for activated C kinase 1, RACK1. Biochim Biophys Acta (2009) 0.86
Identification and analysis of large intergenic non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53-binding sites. Hum Mol Genet (2014) 0.86
Novel mechanism of salt-induced glomerular injury: critical role of eNOS and angiotensin II. J Hypertens (2011) 0.85
Nuclear transportation of diacylglycerol kinase gamma and its possible function in the nucleus. J Biol Chem (2005) 0.83
Association between genomic alterations and metastatic behavior of colorectal cancer identified by array-based comparative genomic hybridization. Genes Chromosomes Cancer (2012) 0.83
Diacylglycerol kinase gamma interacts with and activates beta2-chimaerin, a Rac-specific GAP, in response to epidermal growth factor. FEBS Lett (2007) 0.82
Aberrant methylation of microRNA-34b/c is a predictive marker of metachronous gastric cancer risk. J Gastroenterol (2013) 0.82
p53 negatively regulates the hepatoma growth factor HDGF. Cancer Res (2011) 0.82