Published in Mol Biochem Parasitol on April 20, 2007
Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue. Proc Natl Acad Sci U S A (2011) 2.83
A transcriptional switch underlies commitment to sexual development in malaria parasites. Nature (2014) 2.44
Concentration and purification by magnetic separation of the erythrocytic stages of all human Plasmodium species. Malar J (2008) 2.30
Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system. Cell Host Microbe (2013) 2.29
Strategies for detection of Plasmodium species gametocytes. PLoS One (2013) 1.67
Gametogenesis in malaria parasites is mediated by the cGMP-dependent protein kinase. PLoS Biol (2008) 1.63
Activity of clinically relevant antimalarial drugs on Plasmodium falciparum mature gametocytes in an ATP bioluminescence "transmission blocking" assay. PLoS One (2012) 1.55
A high-throughput screen targeting malaria transmission stages opens new avenues for drug development. J Infect Dis (2011) 1.49
Plasmodium falciparum transmission stages accumulate in the human bone marrow. Sci Transl Med (2014) 1.39
Soft X-ray microscopy analysis of cell volume and hemoglobin content in erythrocytes infected with asexual and sexual stages of Plasmodium falciparum. J Struct Biol (2011) 1.32
Apicoplast and mitochondrion in gametocytogenesis of Plasmodium falciparum. Eukaryot Cell (2008) 1.20
A switch in infected erythrocyte deformability at the maturation and blood circulation of Plasmodium falciparum transmission stages. Blood (2012) 1.19
Identification of MMV malaria box inhibitors of plasmodium falciparum early-stage gametocytes using a luciferase-based high-throughput assay. Antimicrob Agents Chemother (2013) 1.18
Plasmodium falciparum antigens on the surface of the gametocyte-infected erythrocyte. PLoS One (2008) 1.16
The Puf-family RNA-binding protein PfPuf2 regulates sexual development and sex differentiation in the malaria parasite Plasmodium falciparum. J Cell Sci (2010) 1.11
Disruption of a Plasmodium falciparum cyclic nucleotide phosphodiesterase gene causes aberrant gametogenesis. Mol Microbiol (2008) 1.10
Stability of gametocyte-specific Pfs25-mRNA in dried blood spots on filter paper subjected to different storage conditions. Malar J (2012) 1.09
Inferring developmental stage composition from gene expression in human malaria. PLoS Comput Biol (2013) 1.04
Promiscuous expression of α-tubulin II in maturing male and female Plasmodium falciparum gametocytes. PLoS One (2010) 0.99
Type II fatty acid biosynthesis is essential for Plasmodium falciparum sporozoite development in the midgut of Anopheles mosquitoes. Eukaryot Cell (2013) 0.98
Diverse expression patterns of subgroups of the rif multigene family during Plasmodium falciparum gametocytogenesis. PLoS One (2008) 0.98
The role of extracellular vesicles in Plasmodium and other protozoan parasites. Cell Microbiol (2014) 0.95
A flow cytometry-based quantitative drug sensitivity assay for all Plasmodium falciparum gametocyte stages. PLoS One (2014) 0.95
In vitro generation of Plasmodium falciparum ookinetes. Am J Trop Med Hyg (2010) 0.94
High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission. Cell Host Microbe (2015) 0.92
Puf mediates translation repression of transmission-blocking vaccine candidates in malaria parasites. PLoS Pathog (2013) 0.90
Transcriptional profiling defines dynamics of parasite tissue sequestration during malaria infection. Genome Med (2015) 0.90
Structure and non-essential function of glycerol kinase in Plasmodium falciparum blood stages. Mol Microbiol (2008) 0.88
Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules. Antimicrob Agents Chemother (2014) 0.88
Targeting Human Transmission Biology for Malaria Elimination. PLoS Pathog (2015) 0.88
CRISPR-Cas9-modified pfmdr1 protects Plasmodium falciparum asexual blood stages and gametocytes against a class of piperazine-containing compounds but potentiates artemisinin-based combination therapy partner drugs. Mol Microbiol (2016) 0.88
Sex-partitioning of the Plasmodium falciparum stage V gametocyte proteome provides insight into falciparum-specific cell biology. Mol Cell Proteomics (2014) 0.87
Nowhere to hide: interrogating different metabolic parameters of Plasmodium falciparum gametocytes in a transmission blocking drug discovery pipeline towards malaria elimination. Malar J (2015) 0.87
Changes in the transcriptome of the malaria parasite Plasmodium falciparum during the initial phase of transmission from the human to the mosquito. BMC Genomics (2013) 0.86
Integrated transcriptomic and proteomic analyses of P. falciparum gametocytes: molecular insight into sex-specific processes and translational repression. Nucleic Acids Res (2016) 0.85
The role of palmitoylation for protein recruitment to the inner membrane complex of the malaria parasite. J Biol Chem (2014) 0.84
Production of Plasmodium falciparum gametocytes in vitro. Methods Mol Biol (2013) 0.83
cAMP-Signalling Regulates Gametocyte-Infected Erythrocyte Deformability Required for Malaria Parasite Transmission. PLoS Pathog (2015) 0.83
Persistence of Plasmodium falciparum parasitemia after artemisinin combination therapy: evidence from a randomized trial in Uganda. Sci Rep (2016) 0.82
Profiling the Essential Nature of Lipid Metabolism in Asexual Blood and Gametocyte Stages of Plasmodium falciparum. Cell Host Microbe (2015) 0.82
Characterization of the autophagy marker protein Atg8 reveals atypical features of autophagy in Plasmodium falciparum. PLoS One (2014) 0.82
Molecular characterization of the carboxypeptidase B1 of Anopheles stephensi and its evaluation as a target for transmission-blocking vaccines. Infect Immun (2013) 0.81
Sexual development in Plasmodium parasites: knowing when it's time to commit. Nat Rev Microbiol (2015) 0.81
Mutations in the Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL) Confer Multidrug Resistance. MBio (2016) 0.81
Plasmodium falciparum: generation of pure gametocyte culture by heparin treatment. Exp Parasitol (2013) 0.81
Comparison and Optimization of Different Methods for the In Vitro Production of Plasmodium falciparum Gametocytes. J Parasitol Res (2012) 0.81
Expression of a type B RIFIN in Plasmodium falciparum merozoites and gametes. Malar J (2012) 0.80
Evaluation of Plasmodium falciparum gametocyte detection in different patient material. Malar J (2013) 0.78
Specific expression and export of the Plasmodium falciparum Gametocyte EXported Protein-5 marks the gametocyte ring stage. Malar J (2015) 0.78
Changes in lipid composition during sexual development of the malaria parasite Plasmodium falciparum. Malar J (2016) 0.78
Plasmodium Merozoite TRAP Family Protein Is Essential for Vacuole Membrane Disruption and Gamete Egress from Erythrocytes. Cell Host Microbe (2016) 0.77
Transmission-blocking strategies: the roadmap from laboratory bench to the community. Malar J (2016) 0.77
Antibody responses to surface antigens of Plasmodium falciparum gametocyte-infected erythrocytes and their relation to gametocytaemia. Parasite Immunol (2016) 0.76
Splenic retention of Plasmodium falciparum gametocytes to block the transmission of malaria. Antimicrob Agents Chemother (2015) 0.76
The RNA-binding protein Puf1 functions in the maintenance of gametocytes in Plasmodium falciparum. J Cell Sci (2016) 0.75
Sex-Specific Biology of the Human Malaria Parasite Revealed from the Proteomes of Mature Male and Female Gametocytes. Mol Cell Proteomics (2017) 0.75
The development of sexual stage malaria gametocytes in a Wave Bioreactor. Parasit Vectors (2017) 0.75
Role of NF-kβ factor Rel2 during Plasmodium falciparum and bacterial infection in Anopheles dirus. Parasit Vectors (2016) 0.75
Transcriptional Profiling Defines Histone Acetylation as a Regulator of Gene Expression during Human-to-Mosquito Transmission of the Malaria Parasite Plasmodium falciparum. Front Cell Infect Microbiol (2017) 0.75
Development of a potent inhibitor of the Plasmodium proteasome with reduced mammalian toxicity. J Med Chem (2017) 0.75
The genome of the African trypanosome Trypanosoma brucei. Science (2005) 11.48
Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica. Nat Genet (2003) 9.13
Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance. Proc Natl Acad Sci U S A (2004) 8.95
The genome of the kinetoplastid parasite, Leishmania major. Science (2005) 8.64
The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet (2006) 8.02
Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes. J Exp Med (2004) 3.63
A plant-like kinase in Plasmodium falciparum regulates parasite egress from erythrocytes. Science (2010) 3.27
Moderate effect of artemisinin-based combination therapy on transmission of Plasmodium falciparum. J Infect Dis (2006) 3.17
The Plasmodium falciparum sexual development transcriptome: a microarray analysis using ontology-based pattern identification. Mol Biochem Parasitol (2005) 3.02
The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients. J Bacteriol (2008) 2.71
Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials. Malar J (2008) 2.68
Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18. PLoS Genet (2006) 2.47
Highly sensitive detection of malaria parasitemia in a malaria-endemic setting: performance of a new loop-mediated isothermal amplification kit in a remote clinic in Uganda. J Infect Dis (2013) 2.41
Rapid evolution of virulence and drug resistance in the emerging zoonotic pathogen Streptococcus suis. PLoS One (2009) 2.38
Repeated N-acetylcysteine administration alters plasticity-dependent effects of cocaine. J Neurosci (2007) 2.35
World Antimalarial Resistance Network (WARN) III: molecular markers for drug resistant malaria. Malar J (2007) 2.30
Telomeric expression sites are highly conserved in Trypanosoma brucei. PLoS One (2008) 2.22
The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis. Nat Cell Biol (2002) 1.97
Addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children causes a significant but short-lived reduction in infectiousness for mosquitoes. Trop Med Int Health (2004) 1.93
Determination of the processes driving the acquisition of immunity to malaria using a mathematical transmission model. PLoS Comput Biol (2007) 1.87
Mitochondrial DNA targets increase sensitivity of malaria detection using loop-mediated isothermal amplification. J Clin Microbiol (2010) 1.87
Clinical evaluation of a loop-mediated amplification kit for diagnosis of imported malaria. J Infect Dis (2013) 1.73
Combination therapy counteracts the enhanced transmission of drug-resistant malaria parasites to mosquitoes. Antimicrob Agents Chemother (2004) 1.71
Group II metabotropic glutamate receptors modulate extracellular glutamate in the nucleus accumbens. J Pharmacol Exp Ther (2002) 1.70
Chloroquine/sulphadoxine-pyrimethamine for gambian children with malaria: transmission to mosquitoes of multidrug-resistant Plasmodium falciparum. PLoS Clin Trials (2006) 1.69
Plasmodium falciparum gametocyte dynamics in areas of different malaria endemicity. Malar J (2008) 1.69
Loss of population levels of immunity to malaria as a result of exposure-reducing interventions: consequences for interpretation of disease trends. PLoS One (2009) 1.68
RTS,S/AS02A malaria vaccine does not induce parasite CSP T cell epitope selection and reduces multiplicity of infection. PLoS Clin Trials (2006) 1.65
Plasmodium ovale curtisi and Plasmodium ovale wallikeri circulate simultaneously in African communities. Int J Parasitol (2011) 1.64
Epidemiology of subpatent Plasmodium falciparum infection: implications for detection of hotspots with imperfect diagnostics. Malar J (2013) 1.64
Gametogenesis in malaria parasites is mediated by the cGMP-dependent protein kinase. PLoS Biol (2008) 1.63
Malaria transmission after artemether-lumefantrine and dihydroartemisinin-piperaquine: a randomized trial. J Infect Dis (2013) 1.61
Modulation of group II metabotropic glutamate receptor signaling by chronic cocaine. J Pharmacol Exp Ther (2002) 1.59
Seasonal carriage of pfcrt and pfmdr1 alleles in Gambian Plasmodium falciparum imply reduced fitness of chloroquine-resistant parasites. J Infect Dis (2007) 1.58
Residual Plasmodium falciparum parasitemia in Kenyan children after artemisinin-combination therapy is associated with increased transmission to mosquitoes and parasite recurrence. J Infect Dis (2013) 1.52
Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine. Am J Trop Med Hyg (2014) 1.51
Measuring the efficacy of anti-malarial drugs in vivo: quantitative PCR measurement of parasite clearance. Malar J (2010) 1.50
Risk factors for herpes simplex virus transmission to pregnant women: a couples study. Am J Obstet Gynecol (2005) 1.48
Carriage of chloroquine-resistant parasites and delay of effective treatment increase the risk of severe malaria in Gambian children. J Infect Dis (2005) 1.47
A cyclic GMP signalling module that regulates gliding motility in a malaria parasite. PLoS Pathog (2009) 1.46
Differential evidence of natural selection on two leading sporozoite stage malaria vaccine candidate antigens. Int J Parasitol (2006) 1.40
Randomised trial of chloroquine/sulphadoxine-pyrimethamine in Gambian children with malaria: impact against multidrug-resistant P. falciparum. PLoS Clin Trials (2006) 1.39
The malaria parasite cyclic GMP-dependent protein kinase plays a central role in blood-stage schizogony. Eukaryot Cell (2009) 1.39
Amodiaquine resistance in Plasmodium falciparum malaria in Afghanistan is associated with the pfcrt SVMNT allele at codons 72 to 76. Antimicrob Agents Chemother (2010) 1.37
Repeated N-acetyl cysteine reduces cocaine seeking in rodents and craving in cocaine-dependent humans. Neuropsychopharmacology (2010) 1.36
Drug-resistant genotypes and multi-clonality in Plasmodium falciparum analysed by direct genome sequencing from peripheral blood of malaria patients. PLoS One (2011) 1.34
The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism. Nucleic Acids Res (2003) 1.33
Insight into the genome of Aspergillus fumigatus: analysis of a 922 kb region encompassing the nitrate assimilation gene cluster. Fungal Genet Biol (2004) 1.33
An observational study of malaria in British travellers: Plasmodium ovale wallikeri and Plasmodium ovale curtisi differ significantly in the duration of latency. BMJ Open (2013) 1.32
Increased pfmdr1 copy number and sequence polymorphisms in Plasmodium falciparum isolates from Sudanese malaria patients treated with artemether-lumefantrine. Antimicrob Agents Chemother (2011) 1.32
Complete genome of acute rheumatic fever-associated serotype M5 Streptococcus pyogenes strain manfredo. J Bacteriol (2006) 1.30
Impact of RTS,S/AS02(A) and RTS,S/AS01(B) on genotypes of P. falciparum in adults participating in a malaria vaccine clinical trial. PLoS One (2009) 1.26
The perils of PCR: can we accurately 'correct' antimalarial trials? Trends Parasitol (2010) 1.24
Programmed transcription of the var gene family, but not of stevor, in Plasmodium falciparum gametocytes. Eukaryot Cell (2006) 1.22
Thinking outside the cleft to understand synaptic activity: contribution of the cystine-glutamate antiporter (System xc-) to normal and pathological glutamatergic signaling. Pharmacol Rev (2012) 1.21
Stressor- and corticotropin releasing factor-induced reinstatement and active stress-related behavioral responses are augmented following long-access cocaine self-administration by rats. Psychopharmacology (Berl) (2007) 1.20
Markers of anti-malarial drug resistance in Plasmodium falciparum isolates from Swaziland: identification of pfmdr1-86F in natural parasite isolates. Malar J (2010) 1.20
Plasmodium malariae in Haitian refugees, Jamaica. Emerg Infect Dis (2007) 1.18
Malaria parasite cGMP-dependent protein kinase regulates blood stage merozoite secretory organelle discharge and egress. PLoS Pathog (2013) 1.16
Plasmodium falciparum antigens on the surface of the gametocyte-infected erythrocyte. PLoS One (2008) 1.16
Evidence on the chromosomal location of centromeric DNA in Plasmodium falciparum from etoposide-mediated topoisomerase-II cleavage. Proc Natl Acad Sci U S A (2006) 1.15
Levo-tetrahydropalmatine attenuates cocaine self-administration and cocaine-induced reinstatement in rats. Psychopharmacology (Berl) (2007) 1.15
Genetic complexity of Plasmodium falciparum gametocytes isolated from the peripheral blood of treated Gambian children. Am J Trop Med Hyg (2002) 1.15
Segregating YKU80 and TLC1 alleles underlying natural variation in telomere properties in wild yeast. PLoS Genet (2009) 1.14
Involvement of noradrenergic neurotransmission in the stress- but not cocaine-induced reinstatement of extinguished cocaine-induced conditioned place preference in mice: role for β-2 adrenergic receptors. Neuropsychopharmacology (2010) 1.14
Distinct trafficking and localization of STEVOR proteins in three stages of the Plasmodium falciparum life cycle. Infect Immun (2004) 1.14
ama1 genes of sympatric Plasmodium vivax and P. falciparum from Venezuela differ significantly in genetic diversity and recombination frequency. PLoS One (2008) 1.13
Augmented cocaine seeking in response to stress or CRF delivered into the ventral tegmental area following long-access self-administration is mediated by CRF receptor type 1 but not CRF receptor type 2. J Neurosci (2011) 1.13
A novel cyclic GMP-dependent protein kinase is expressed in the ring stage of the Plasmodium falciparum life cycle. Mol Microbiol (2002) 1.12
Dynamics of pfcrt alleles CVMNK and CVIET in chloroquine-treated Sudanese patients infected with Plasmodium falciparum. Malar J (2010) 1.10
Multiple splice variants encode a novel adenylyl cyclase of possible plastid origin expressed in the sexual stage of the malaria parasite Plasmodium falciparum. J Biol Chem (2003) 1.10
Disruption of a Plasmodium falciparum cyclic nucleotide phosphodiesterase gene causes aberrant gametogenesis. Mol Microbiol (2008) 1.10
Wear and surface cracking in early retrieved highly cross-linked polyethylene acetabular liners. J Bone Joint Surg Am (2004) 1.09
Hot spot or not: a comparison of spatial statistical methods to predict prospective malaria infections. Malar J (2014) 1.09
High sequence diversity and evidence of balancing selection in the Pvmsp3alpha gene of Plasmodium vivax in the Venezuelan Amazon. Mol Biochem Parasitol (2005) 1.06
Gene arrays at Pneumocystis carinii telomeres. Genetics (2005) 1.02
Sympatric Plasmodium falciparum isolates from Venezuela have structured var gene repertoires. Malar J (2003) 1.02
Daily cocaine self-administration under long-access conditions augments restraint-induced increases in plasma corticosterone and impairs glucocorticoid receptor-mediated negative feedback in rats. Brain Res (2007) 1.01
Human immune responses that reduce the transmission of Plasmodium falciparum in African populations. Int J Parasitol (2010) 1.01
Culture-adapted Plasmodium falciparum isolates from UK travellers: in vitro drug sensitivity, clonality and drug resistance markers. Malar J (2013) 1.00
Control of endothelial sprouting by a Tel-CtBP complex. Nat Cell Biol (2010) 0.99
Promiscuous expression of α-tubulin II in maturing male and female Plasmodium falciparum gametocytes. PLoS One (2010) 0.99
Filter paper collection of Plasmodium falciparum mRNA for detecting low-density gametocytes. Malar J (2012) 0.99
Corticosterone acts in the nucleus accumbens to enhance dopamine signaling and potentiate reinstatement of cocaine seeking. J Neurosci (2013) 0.98
Oral administration of levo-tetrahydropalmatine attenuates reinstatement of extinguished cocaine seeking by cocaine, stress or drug-associated cues in rats. Drug Alcohol Depend (2010) 0.98
Cluster of falciparum malaria cases in UK airport. Emerg Infect Dis (2008) 0.97
PlasmoView: a web-based resource to visualise global Plasmodium falciparum genomic variation. J Infect Dis (2013) 0.97
Comprehensive computational design of mCreI homing endonuclease cleavage specificity for genome engineering. Nucleic Acids Res (2011) 0.97
Increased sensitivity for detecting malaria parasites in human umbilical cord blood using scaled-up DNA preparation. Malar J (2012) 0.96
Changes in malaria parasite drug resistance in an endemic population over a 25-year period with resulting genomic evidence of selection. J Infect Dis (2013) 0.95