Published in Learn Mem on May 03, 2007
BDNF is essential to promote persistence of long-term memory storage. Proc Natl Acad Sci U S A (2008) 2.16
Cognitive aging: a common decline of episodic recollection and spatial memory in rats. J Neurosci (2008) 1.43
Influence of late-life exposure to environmental enrichment or exercise on hippocampal function and CA1 senescent physiology. Neurobiol Aging (2011) 1.03
Age-related impairments in memory and in CREB and pCREB expression in hippocampus and amygdala following inhibitory avoidance training. Mech Ageing Dev (2012) 0.90
Intra-amygdala injections of CREB antisense impair inhibitory avoidance memory: role of norepinephrine and acetylcholine. Learn Mem (2008) 0.88
Blueberry supplementation induces spatial memory improvements and region-specific regulation of hippocampal BDNF mRNA expression in young rats. Psychopharmacology (Berl) (2012) 0.87
Neural Protein Synthesis during Aging: Effects on Plasticity and Memory. Front Aging Neurosci (2010) 0.84
The PDE4 inhibitor HT-0712 improves hippocampus-dependent memory in aged mice. Neuropsychopharmacology (2014) 0.83
Epinephrine and glucose modulate training-related CREB phosphorylation in old rats: relationships to age-related memory impairments. Exp Gerontol (2012) 0.80
Sleep deprivation impairs recall of social transmission of food preference in rats. Nat Sci Sleep (2014) 0.78
Hyponeophagia: a measure of anxiety in the mouse. J Vis Exp (2011) 0.78
Phosphodiesterase inhibitors as therapeutics for traumatic brain injury. Curr Pharm Des (2015) 0.78
Acetylcholine release in the hippocampus and prelimbic cortex during acquisition of a socially transmitted food preference. Neurobiol Learn Mem (2011) 0.77
Forgetfulness during aging: an integrated biology. Neurobiol Learn Mem (2014) 0.76
Exercise Counteracts Aging-Related Memory Impairment: A Potential Role for the Astrocytic Metabolic Shuttle. Front Aging Neurosci (2016) 0.75
The Role of Dorsal Hippocampal Dopamine D1-Type Receptors in Social Learning, Social Interactions, and Food Intake in Male and Female Mice. Neuropsychopharmacology (2017) 0.75
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81
Memory--a century of consolidation. Science (2000) 12.95
The molecular biology of memory storage: a dialogue between genes and synapses. Science (2001) 11.85
Genetic enhancement of learning and memory in mice. Nature (1999) 8.06
Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain. J Neurochem (1966) 7.91
Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. J Comp Physiol Psychol (1979) 6.07
CREB and memory. Annu Rev Neurosci (1998) 4.76
Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory. J Neurosci (2000) 4.55
Severity of spatial learning impairment in aging: development of a learning index for performance in the Morris water maze. Behav Neurosci (1993) 4.33
The long and the short of long-term memory--a molecular framework. Nature (1986) 3.68
Stimulation of cAMP response element (CRE)-mediated transcription during contextual learning. Nat Neurosci (1998) 3.33
Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation. Nature (1990) 2.85
Persistence of long-term memory storage requires a late protein synthesis- and BDNF- dependent phase in the hippocampus. Neuron (2007) 2.63
cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase. Cell (1994) 2.59
Combinatorial amygdalar inputs to hippocampal domains and hypothalamic behavior systems. Brain Res Brain Res Rev (2001) 2.59
Induction of CRE-mediated gene expression by stimuli that generate long-lasting LTP in area CA1 of the hippocampus. Neuron (1996) 2.47
The use of animal models to study the effects of aging on cognition. Annu Rev Psychol (1997) 2.32
Antisense oligodeoxynucleotide-mediated disruption of hippocampal cAMP response element binding protein levels impairs consolidation of memory for water maze training. Proc Natl Acad Sci U S A (1997) 2.23
Involvement of hippocampal cAMP/cAMP-dependent protein kinase signaling pathways in a late memory consolidation phase of aversively motivated learning in rats. Proc Natl Acad Sci U S A (1997) 2.20
Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease. J Neurosci (2001) 2.15
Long-term memory underlying hippocampus-dependent social recognition in mice. Hippocampus (2000) 2.08
Spaced training induces normal long-term memory in CREB mutant mice. Curr Biol (1997) 2.07
Activation of mitogen-activated protein kinase/extracellular signal-regulated kinase in hippocampal circuitry is required for consolidation and reconsolidation of recognition memory. J Neurosci (2003) 1.86
CREB and the formation of long-term memory. Curr Opin Neurobiol (1996) 1.80
Cellular senescence impairs circadian expression of clock genes in vitro and in vivo. Circ Res (2006) 1.68
Spatial learning and motor deficits in aged rats. Neurobiol Aging (1984) 1.60
Selective damage to the hippocampal region blocks long-term retention of a natural and nonspatial stimulus-stimulus association. Hippocampus (1995) 1.59
Anterograde and retrograde amnesia in rats with dorsal hippocampal or dorsomedial thalamic lesions. Behav Brain Res (1990) 1.48
Deficits in memory tasks of mice with CREB mutations depend on gene dosage. Learn Mem (1999) 1.45
Animal models of normal aging: relationship between cognitive decline and markers in hippocampal circuitry. Behav Brain Res (1993) 1.41
Calcineurin links Ca2+ dysregulation with brain aging. J Neurosci (2001) 1.41
Consolidation of CS and US representations in associative fear conditioning. Hippocampus (2004) 1.39
Anterograde amnesia and temporally graded retrograde amnesia for a nonspatial memory task after lesions of hippocampus and subiculum. J Neurosci (2002) 1.37
Phosphorylated cAMP response element binding protein in the mouse brain after fear conditioning: relationship to Fos production. Brain Res Mol Brain Res (2001) 1.37
Involvement of hippocampal synaptic plasticity in age-related memory decline. Brain Res Brain Res Rev (1999) 1.35
An evaluation of spatial information processing in aged rats. Behav Neurosci (1987) 1.33
Dynamics of hippocampal and cortical activation during consolidation of a nonspatial memory. J Neurosci (2006) 1.32
Calcium dysregulation in neuronal aging and Alzheimer's disease: history and new directions. Cell Calcium (1999) 1.29
The calcium rationale in aging and Alzheimer's disease. Evidence from an animal model of normal aging. Ann N Y Acad Sci (1994) 1.28
Auditory fear conditioning and long-term potentiation in the lateral amygdala require ERK/MAP kinase signaling in the auditory thalamus: a role for presynaptic plasticity in the fear system. J Neurosci (2005) 1.23
An age comparison of the rates of acquisition and forgetting of spatial information in relation to long-term enhancement of hippocampal synapses. Behav Neurosci (1985) 1.22
Individual differences in aging: behavioral and neurobiological correlates. Neurobiol Aging (1989) 1.22
Foreground contextual fear memory consolidation requires two independent phases of hippocampal ERK/CREB activation. Learn Mem (2006) 1.18
Anterograde and retrograde amnesia in rats with large hippocampal lesions. Hippocampus (2001) 1.16
Molecular pharmacological dissection of short- and long-term memory. Cell Mol Neurobiol (2002) 1.13
Direct evidence for biphasic cAMP responsive element-binding protein phosphorylation during long-term potentiation in the rat dentate gyrus in vivo. J Neurosci (1999) 1.12
Glucose, memory, and aging. Am J Clin Nutr (1998) 1.11
The many faces of amnesia. Learn Mem (2006) 1.10
Spatial memory is related to hippocampal subcellular concentrations of calcium-dependent protein kinase C isoforms in young and aged rats. Proc Natl Acad Sci U S A (1997) 1.09
The aged mouse as a model of cognitive decline with special emphasis on studies in NMRI mice. Behav Brain Res (1993) 1.08
Forced swimming evokes a biphasic response in CREB phosphorylation in extrahypothalamic limbic and neocortical brain structures in the rat. Eur J Neurosci (2002) 1.05
Hippocampal CREB1 but not CREB2 is decreased in aged rats with spatial memory impairments. Neurobiol Learn Mem (2004) 1.05
Regional changes in the hippocampal density of AMPA and NMDA receptors across the lifespan of the rat. Brain Res (2000) 1.04
Alterations of cAMP response element-binding activity in the aged rat brain in response to administration of rolipram, a cAMP-specific phosphodiesterase inhibitor. Brain Res Mol Brain Res (1996) 1.01
CREB phosphorylation and c-Fos expression in the hippocampus of rats during acquisition and recall of a socially transmitted food preference. Hippocampus (2005) 0.96
Dysregulation of memory-related proteins in the hippocampus of aged rats and their relation with cognitive impairment. Hippocampus (2005) 0.95
Temporal characteristics of amnesia induced by protein synthesis inhibitor: determination by shock level. Nature (1970) 0.95
Hippocampal formation lesions impair performance in an odor-odor association task independently of spatial context. Neurobiol Learn Mem (2002) 0.95
Age-related learning and memory deficits in odor-reward association in rats. Neurobiol Aging (1996) 0.93
Rapid, labile, and protein synthesis-independent short-term memory in conditioned taste aversion. Learn Mem (1999) 0.93
Hippocampal overexpression of mutant creb blocks long-term, but not short-term memory for a socially transmitted food preference. Learn Mem (2005) 0.93
Rapid forgetting in aged rats. Behav Neural Biol (1982) 0.92
Socially transmitted food preferences can be used to study long-term memory in rats. Learn Behav (2003) 0.92
Combined lesions of hippocampus and subiculum Do not produce deficits in a nonspatial social olfactory memory task. J Neurosci (2000) 0.91
Age and stress history effects on spatial performance in a swim task in Fischer-344 rats. Neurobiol Learn Mem (1996) 0.88
Age-related disturbance of memory and CREB phosphorylation in CA1 area of hippocampus of rats. Brain Res (2005) 0.87
Variable decay of memory and its recovery in cycloheximide-treated mice. Proc Natl Acad Sci U S A (1972) 0.87
Transcriptional mechanisms of hippocampal aging. Exp Gerontol (2004) 0.87
Enhancing cognitive function across the life span. Ann N Y Acad Sci (2002) 0.86
A two focal plane method for digital quantification of nuclear immunoreactivity in large brain areas using NIH-image software. Brain Res Brain Res Protoc (1998) 0.86
Anterograde and retrograde amnesia after lesions to frontal cortex in rats. J Neurosci (1999) 0.85
Age-related changes in spontaneous behavior and learning in NMRI mice from middle to old age. Physiol Behav (1992) 0.82
NMDA receptor antagonists impair memory for nonspatial, socially transmitted food preference. Behav Neurosci (2002) 0.82
Glucose regulation of memory for reward reduction in young and aged rats. Neurobiol Aging (2005) 0.81
Long-term memory loss in senescent rats: neuropsychological analysis of interference and context effects. Psychol Aging (1988) 0.80
Age-related deficits in retention of the classically conditioned nictitating membrane response in rabbits. Behav Neurosci (1995) 0.79
Achieving and maintaining cognitive vitality with aging. Mayo Clin Proc (2002) 1.81
Lactate produced by glycogenolysis in astrocytes regulates memory processing. PLoS One (2011) 1.51
Switching memory systems during learning: changes in patterns of brain acetylcholine release in the hippocampus and striatum in rats. J Neurosci (2003) 1.47
Relationship of enhanced norepinephrine activity during memory consolidation to enhanced long-term memory in humans. Am J Psychiatry (2002) 1.18
Amnesia produced by altered release of neurotransmitters after intraamygdala injections of a protein synthesis inhibitor. Proc Natl Acad Sci U S A (2007) 1.13
Diencephalic damage decreases hippocampal acetylcholine release during spontaneous alternation testing. Learn Mem (2003) 1.06
Different temporal profiles of amnesia after intra-hippocampus and intra-amygdala infusions of anisomycin. Behav Neurosci (2007) 1.04
Intra-hippocampal lidocaine injections impair acquisition of a place task and facilitate acquisition of a response task in rats. Behav Brain Res (2003) 1.03
Cooperation between memory systems: acetylcholine release in the amygdala correlates positively with performance on a hippocampus-dependent task. Behav Neurosci (2003) 1.02
Food for thought: fluctuations in brain extracellular glucose provide insight into the mechanisms of memory modulation. Behav Cogn Neurosci Rev (2002) 1.02
Impaired and spared cholinergic functions in the hippocampus after lesions of the medial septum/vertical limb of the diagonal band with 192 IgG-saporin. Hippocampus (2004) 1.02
Microdialysis measures of functional increases in ACh release in the hippocampus with and without inclusion of acetylcholinesterase inhibitors in the perfusate. J Neurochem (2006) 0.99
Competition between memory systems: acetylcholine release in the hippocampus correlates negatively with good performance on an amygdala-dependent task. J Neurosci (2002) 0.99
Inactivation of dorsolateral striatum impairs acquisition of response learning in cue-deficient, but not cue-available, conditions. Behav Neurosci (2004) 0.98
Patterns of brain acetylcholine release predict individual differences in preferred learning strategies in rats. Neurobiol Learn Mem (2003) 0.98
Intrahippocampal infusions of anisomycin produce amnesia: contribution of increased release of norepinephrine, dopamine, and acetylcholine. Learn Mem (2009) 0.95
Acetylcholine release in hippocampus and striatum during testing on a rewarded spontaneous alternation task. Neurobiol Learn Mem (2005) 0.95
Acetylcholine release in the hippocampus and striatum during place and response training. Learn Mem (2005) 0.94
Age-related impairments in memory and in CREB and pCREB expression in hippocampus and amygdala following inhibitory avoidance training. Mech Ageing Dev (2012) 0.90
Glucose injections into the dorsal hippocampus or dorsolateral striatum of rats prior to T-maze training: modulation of learning rates and strategy selection. Learn Mem (2005) 0.89
Modulation of memory with septal injections of morphine and glucose: effects on extracellular glucose levels in the hippocampus. Physiol Behav (2005) 0.89
Protein synthesis and memory. Introduction. Neurobiol Learn Mem (2008) 0.88
Age-related changes in memory and in acetylcholine functions in the hippocampus in the Ts65Dn mouse, a model of Down syndrome. Neurobiol Learn Mem (2007) 0.88
Intra-amygdala injections of CREB antisense impair inhibitory avoidance memory: role of norepinephrine and acetylcholine. Learn Mem (2008) 0.88
Increases in extracellular fluid glucose levels in the rat hippocampus following an anesthetic dose of pentobarbital or ketamine-xylazine: an in vivo microdialysis study. Physiol Behav (2004) 0.87
VRX-03011, a novel 5-HT4 agonist, enhances memory and hippocampal acetylcholine efflux. Neuropharmacology (2007) 0.86
Effects of stress, corticosterone, and epinephrine administration on learning in place and response tasks. Behav Brain Res (2009) 0.86
Age-related memory impairments due to reduced blood glucose responses to epinephrine. Neurobiol Aging (2009) 0.85
Effects of injections of glucose into the dorsal striatum on learning of place and response mazes. Behav Brain Res (2005) 0.83
Vagotomy attenuates effects of L-glucose but not of D-glucose on spontaneous alternation performance. Physiol Behav (2002) 0.83
Lidocaine attenuates anisomycin-induced amnesia and release of norepinephrine in the amygdala. Neurobiol Learn Mem (2011) 0.82
Signals from the brainstem sleep/wake centers regulate behavioral timing via the circadian clock. PLoS One (2013) 0.81
Use it and boost it with physical and mental activity. Hippocampus (2013) 0.81
Glucose regulation of memory for reward reduction in young and aged rats. Neurobiol Aging (2005) 0.81
Epinephrine and glucose modulate training-related CREB phosphorylation in old rats: relationships to age-related memory impairments. Exp Gerontol (2012) 0.80
Acetylcholine: cognitive and brain functions. Neurobiol Learn Mem (2003) 0.79
Glucose attenuates impairments in memory and CREB activation produced by an α4β2 but not an α7 nicotinic receptor antagonist. Neuropharmacology (2012) 0.77
Multiple memory systems. Neurobiol Learn Mem (2004) 0.75