Endogenous endostatin inhibits choroidal neovascularization.

PubWeight™: 1.03‹?› | Rank: Top 15%

🔗 View Article (PMID 17526870)

Published in FASEB J on May 25, 2007

Authors

Alexander G Marneros1, Haicheng She, Hadi Zambarakji, Hiroya Hashizume, Edward J Connolly, Ivana Kim, Evangelos S Gragoudas, Joan W Miller, Bjorn R Olsen

Author Affiliations

1: Department of Developmental Biology, Harvard School of Dental Medicine, 188 Longwood Ave., Boston, MA 02115, USA. alexander_marneros@yahoo.com

Articles citing this

Heparan sulfate proteoglycans. Cold Spring Harb Perspect Biol (2011) 2.96

Macrophages are essential for the early wound healing response and the formation of a fibrovascular scar. Am J Pathol (2013) 1.12

Neuroprotectin D1 attenuates laser-induced choroidal neovascularization in mouse. Mol Vis (2010) 1.06

Increased choroidal neovascularization following laser induction in mice lacking lysyl oxidase-like 1. Invest Ophthalmol Vis Sci (2008) 1.01

Endostatin and anastellin inhibit distinct aspects of the angiogenic process. J Exp Clin Cancer Res (2008) 0.88

Endothelial TWIST1 promotes pathological ocular angiogenesis. Invest Ophthalmol Vis Sci (2014) 0.85

Variations in COL15A1 and COL18A1 influence age of onset of primary open angle glaucoma. Clin Genet (2013) 0.84

The potential of nanomedicine therapies to treat neovascular disease in the retina. J Angiogenes Res (2010) 0.84

Exosomes from retinal astrocytes contain antiangiogenic components that inhibit laser-induced choroidal neovascularization. J Biol Chem (2013) 0.84

Broad spectrum antiangiogenic treatment for ocular neovascular diseases. PLoS One (2010) 0.84

Treatment of age-related macular degeneration: beyond VEGF. Jpn J Ophthalmol (2010) 0.83

Topical application of recombinant calreticulin peptide, vasostatin 48, alleviates laser-induced choroidal neovascularization in rats. Mol Vis (2010) 0.82

Utilizing targeted gene therapy with nanoparticles binding alpha v beta 3 for imaging and treating choroidal neovascularization. PLoS One (2011) 0.81

Heat treatment of retinal pigment epithelium induces production of elastic lamina components and antiangiogenic activity. FASEB J (2011) 0.81

Image-based assessment of microvascular function and structure in collagen XV- and XVIII-deficient mice. J Physiol (2013) 0.80

A Hypothesis Concerning the Biphasic Dose-response of Tumors to Angiostatin and Endostatin. Dose Response (2015) 0.77

Antiangiogenic and Neurogenic Activities of Sleeping Beauty-Mediated PEDF-Transfected RPE Cells In Vitro and In Vivo. Biomed Res Int (2015) 0.76

Articles by these authors

Age-related macular degeneration. N Engl J Med (2008) 7.49

VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature. Am J Physiol Heart Circ Physiol (2005) 5.56

Conversion of vascular endothelial cells into multipotent stem-like cells. Nat Med (2010) 4.88

Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts. Am J Pathol (2004) 4.47

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc Natl Acad Sci U S A (2010) 4.30

Functionally specialized junctions between endothelial cells of lymphatic vessels. J Exp Med (2007) 4.10

Suppressed NFAT-dependent VEGFR1 expression and constitutive VEGFR2 signaling in infantile hemangioma. Nat Med (2008) 3.98

Cellular abnormalities of blood vessels as targets in cancer. Curr Opin Genet Dev (2005) 3.38

Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts. Nat Cell Biol (2008) 2.85

Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3. Mol Biol Cell (2008) 2.78

Intracellular VEGF regulates the balance between osteoblast and adipocyte differentiation. J Clin Invest (2012) 2.58

Prevention of experimental choroidal neovascularization with intravitreal anti-vascular endothelial growth factor antibody fragment. Arch Ophthalmol (2002) 2.57

Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development (2002) 2.57

Neuronal loss and brain atrophy in mice lacking cathepsins B and L. Proc Natl Acad Sci U S A (2002) 2.54

VEGFA is necessary for chondrocyte survival during bone development. Development (2004) 2.54

VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization. J Exp Med (2003) 2.52

Vascular endothelial growth factor expression in the retinal pigment epithelium is essential for choriocapillaris development and visual function. Am J Pathol (2005) 2.38

Tumor necrosis factor-alpha mediates oligodendrocyte death and delayed retinal ganglion cell loss in a mouse model of glaucoma. J Neurosci (2006) 2.37

Conversion to aflibercept for chronic refractory or recurrent neovascular age-related macular degeneration. Am J Ophthalmol (2013) 2.32

NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism. J Clin Invest (2008) 2.29

Monocyte chemoattractant protein 1 mediates retinal detachment-induced photoreceptor apoptosis. Proc Natl Acad Sci U S A (2007) 2.20

Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis. Proc Natl Acad Sci U S A (2010) 2.20

Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice. Cell (2007) 2.18

Lack of collagen XVIII/endostatin results in eye abnormalities. EMBO J (2002) 2.13

Identification of signaling pathways regulating primary cilium length and flow-mediated adaptation. Curr Biol (2010) 2.08

Anti-vascular endothelial growth factor therapy for ocular neovascular disease. Curr Opin Ophthalmol (2007) 2.08

Increased expression of the collagen receptor discoidin domain receptor 2 in articular cartilage as a key event in the pathogenesis of osteoarthritis. Arthritis Rheum (2007) 2.07

Verteporfin therapy of subfoveal choroidal neovascularization in pathologic myopia: 2-year results of a randomized clinical trial--VIP report no. 3. Ophthalmology (2003) 1.96

DNA sequence variants in the LOXL1 gene are associated with pseudoexfoliation glaucoma in a U.S. clinic-based population with broad ethnic diversity. BMC Med Genet (2008) 1.95

VEGF and c-Met blockade amplify angiogenesis inhibition in pancreatic islet cancer. Cancer Res (2011) 1.92

Tie receptors and their angiopoietin ligands are context-dependent regulators of vascular remodeling. Exp Cell Res (2005) 1.92

The genetic basis for skeletal diseases. Nature (2003) 1.92

Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels. Am J Pathol (2009) 1.87

Germline BAP1 inactivation is preferentially associated with metastatic ocular melanoma and cutaneous-ocular melanoma families. PLoS One (2012) 1.76

Multiple roles of vascular endothelial growth factor (VEGF) in skeletal development, growth, and repair. Curr Top Dev Biol (2005) 1.75

Verteporfin therapy of subfoveal choroidal neovascularization in patients with age-related macular degeneration: additional information regarding baseline lesion composition's impact on vision outcomes-TAP report No. 3. Arch Ophthalmol (2002) 1.71

Reproducibility of retinal thickness measurements on normal and pathologic eyes by different optical coherence tomography instruments. Am J Ophthalmol (2010) 1.71

The expanded clinical spectrum of deferoxamine retinopathy. Ophthalmology (2002) 1.70

Histologic correlation of in vivo optical coherence tomography images of the human retina. Am J Ophthalmol (2006) 1.68

Mutations in a novel factor, glomulin, are responsible for glomuvenous malformations ("glomangiomas"). Am J Hum Genet (2002) 1.66

Knobloch syndrome: novel mutations in COL18A1, evidence for genetic heterogeneity, and a functionally impaired polymorphism in endostatin. Hum Mutat (2004) 1.61

Editorial: Journal of negative results in biomedicine. J Negat Results Biomed (2002) 1.58

Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development. Development (2004) 1.58

Localization of collagen XVIII and the endostatin portion of collagen XVIII in aged human control eyes and eyes with age-related macular degeneration. Invest Ophthalmol Vis Sci (2004) 1.56

FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosis. J Cell Biol (2008) 1.53

Verteporfin therapy for subfoveal choroidal neovascularization in age-related macular degeneration: three-year results of an open-label extension of 2 randomized clinical trials--TAP Report no. 5. Arch Ophthalmol (2002) 1.53

Activation of the discoidin domain receptor 2 induces expression of matrix metalloproteinase 13 associated with osteoarthritis in mice. J Biol Chem (2004) 1.53

Heparan sulfate chains of perlecan are indispensable in the lens capsule but not in the kidney. EMBO J (2003) 1.53

Adjuvant interferon therapy for patients with uveal melanoma at high risk of metastasis. Ophthalmology (2009) 1.51

Maximum tolerated dose of a humanized anti-vascular endothelial growth factor antibody fragment for treating neovascular age-related macular degeneration. Ophthalmology (2005) 1.47

Proton irradiation for peripapillary and parapapillary melanomas. Arch Ophthalmol (2011) 1.45

Characterization of cytokine responses to retinal detachment in rats. Mol Vis (2006) 1.43

The role of backscattering in SHG tissue imaging. Biophys J (2007) 1.43

Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression. Cancer Res (2004) 1.42

Cherubism: best clinical practice. Orphanet J Rare Dis (2012) 1.42

Caspase activation in an experimental model of retinal detachment. Invest Ophthalmol Vis Sci (2003) 1.40

Physiological role of collagen XVIII and endostatin. FASEB J (2005) 1.40

Cigarette smoking, CFH, APOE, ELOVL4, and risk of neovascular age-related macular degeneration. Arch Ophthalmol (2007) 1.37

Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration. Proc Natl Acad Sci U S A (2012) 1.37

Etanercept, a widely used inhibitor of tumor necrosis factor-α (TNF-α), prevents retinal ganglion cell loss in a rat model of glaucoma. PLoS One (2012) 1.35

Differential expression of CD146 in tissues and endothelial cells derived from infantile haemangioma and normal human skin. J Pathol (2003) 1.35

Genome scans provide evidence for keloid susceptibility loci on chromosomes 2q23 and 7p11. J Invest Dermatol (2004) 1.34

Targeted disruption of the CD18 or ICAM-1 gene inhibits choroidal neovascularization. Invest Ophthalmol Vis Sci (2003) 1.34

Collagen XVIII/endostatin is essential for vision and retinal pigment epithelial function. EMBO J (2003) 1.34

Attenuated glial reactions and photoreceptor degeneration after retinal detachment in mice deficient in glial fibrillary acidic protein and vimentin. Invest Ophthalmol Vis Sci (2007) 1.33

Predictors of visual outcome and choroidal neovascular membrane formation after traumatic choroidal rupture. Arch Ophthalmol (2006) 1.32

Loss of collagen XVIII enhances neovascularization and vascular permeability in atherosclerosis. Circulation (2004) 1.30

Alleles in the HtrA serine peptidase 1 gene alter the risk of neovascular age-related macular degeneration. Ophthalmology (2007) 1.30

Molecular interplay between endostatin, integrins, and heparan sulfate. J Biol Chem (2009) 1.25

FAS-mediated apoptosis and its relation to intrinsic pathway activation in an experimental model of retinal detachment. Invest Ophthalmol Vis Sci (2004) 1.24

Progression of calvarial bone development requires Foxc1 regulation of Msx2 and Alx4. Dev Biol (2003) 1.23

The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration. BMC Med Genet (2008) 1.22

Identification of Chlamydia pneumoniae within human choroidal neovascular membranes secondary to age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol (2005) 1.20

Acute severe visual acuity decrease after photodynamic therapy with verteporfin: case reports from randomized clinical trials-TAP and VIP report no. 3. Am J Ophthalmol (2004) 1.19

Targeted disruption of Col8a1 and Col8a2 genes in mice leads to anterior segment abnormalities in the eye. FASEB J (2005) 1.18

Successful treatment of Fusarium endophthalmitis with voriconazole and Aspergillus endophthalmitis with voriconazole plus caspofungin. Am J Ophthalmol (2005) 1.17

Kinesin-2 controls development and patterning of the vertebrate skeleton by Hedgehog- and Gli3-dependent mechanisms. Dev Biol (2007) 1.15

In vivo evaluation of laser-induced choroidal neovascularization using spectral-domain optical coherence tomography. Invest Ophthalmol Vis Sci (2011) 1.14

Preliminary results of gene therapy for retinal degeneration. N Engl J Med (2008) 1.14

Vascular adhesion protein-1 blockade suppresses choroidal neovascularization. FASEB J (2008) 1.14

Review of anti-VEGF therapy in proliferative diabetic retinopathy. Semin Ophthalmol (2009) 1.13

Treatment of metastatic tumors of the choroid with proton beam irradiation. Ophthalmology (2005) 1.11

HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in mice. J Clin Invest (2008) 1.11

Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration. Hum Genomics (2011) 1.08

Inhibition of Hsp90 attenuates inflammation in endotoxin-induced uveitis. FASEB J (2007) 1.08

Comprehensive analysis of complement factor H and LOC387715/ARMS2/HTRA1 variants with respect to phenotype in advanced age-related macular degeneration. Am J Ophthalmol (2009) 1.08