PubRank

Thilo Dörk

Author PubWeight™ 188.98‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 2007 29.23
2 Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet 2013 8.24
3 A common coding variant in CASP8 is associated with breast cancer risk. Nat Genet 2007 7.35
4 Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet 2009 7.30
5 Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genet 2008 6.22
6 Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Nat Genet 2009 6.04
7 Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies. J Natl Cancer Inst 2010 4.54
8 A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Nat Genet 2009 4.38
9 Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet 2013 4.35
10 A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24. Nat Genet 2010 3.86
11 Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet 2013 3.81
12 Dominant negative ATM mutations in breast cancer families. J Natl Cancer Inst 2002 3.46
13 GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. Nat Genet 2013 3.42
14 Genome-wide association analysis identifies three new breast cancer susceptibility loci. Nat Genet 2012 3.20
15 Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. Nat Genet 2011 3.07
16 Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium. Cancer Epidemiol Biomarkers Prev 2008 3.05
17 Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042. J Natl Cancer Inst 2009 2.88
18 Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium. Hum Mol Genet 2011 2.72
19 Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers. Am J Hum Genet 2013 2.24
20 Nonsense mutation p.Q548X in BLM, the gene mutated in Bloom's syndrome, is associated with breast cancer in Slavic populations. Breast Cancer Res Treat 2012 2.19
21 The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing. Clin Cancer Res 2011 2.09
22 Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk. PLoS Genet 2013 1.88
23 Functional consequences of ATM sequence variants for chromosomal radiosensitivity. Genes Chromosomes Cancer 2004 1.76
24 A new type of mutation causes a splicing defect in ATM. Nat Genet 2002 1.74
25 Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer. Nat Commun 2013 1.73
26 Association of ESR1 gene tagging SNPs with breast cancer risk. Hum Mol Genet 2009 1.58
27 Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium. Hum Mol Genet 2011 1.56
28 Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder. Am J Hum Genet 2009 1.54
29 Nonclassical splicing mutations in the coding and noncoding regions of the ATM Gene: maximum entropy estimates of splice junction strengths. Hum Mutat 2004 1.53
30 A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease. Hum Mol Genet 2012 1.47
31 Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1. Am J Hum Genet 2013 1.39
32 Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31. Nat Commun 2013 1.36
33 Do MDM2 SNP309 and TP53 R72P interact in breast cancer susceptibility? A large pooled series from the breast cancer association consortium. Cancer Res 2007 1.29
34 Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium. Cancer Epidemiol Biomarkers Prev 2009 1.29
35 CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer. J Clin Oncol 2012 1.29
36 Immaturity, perinatal inflammation, and retinopathy of prematurity: a multi-hit hypothesis. Early Hum Dev 2009 1.27
37 11q13 is a susceptibility locus for hormone receptor positive breast cancer. Hum Mutat 2012 1.26
38 Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer. Cancer Epidemiol Biomarkers Prev 2011 1.23
39 The role of genetic breast cancer susceptibility variants as prognostic factors. Hum Mol Genet 2012 1.23
40 Functional polymorphisms in the TERT promoter are associated with risk of serous epithelial ovarian and breast cancers. PLoS One 2011 1.20
41 Nijmegen Breakage Syndrome mutations and risk of breast cancer. Int J Cancer 2008 1.14
42 Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC). PLoS One 2012 1.13
43 Family history, genetic testing, and clinical risk prediction: pooled analysis of CHEK2 1100delC in 1,828 bilateral breast cancers and 7,030 controls. Cancer Epidemiol Biomarkers Prev 2009 1.13
44 Association of two mutations in the CHEK2 gene with breast cancer. Int J Cancer 2005 1.12
45 A role for XRCC2 gene polymorphisms in breast cancer risk and survival. J Med Genet 2011 1.10
46 Genome-wide association study identifies a possible susceptibility locus for endometrial cancer. Cancer Epidemiol Biomarkers Prev 2012 1.02
47 Combined effects of single nucleotide polymorphisms TP53 R72P and MDM2 SNP309, and p53 expression on survival of breast cancer patients. Breast Cancer Res 2009 1.01
48 PALB2 mutations in German and Russian patients with bilateral breast cancer. Breast Cancer Res Treat 2010 1.01
49 A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium. Hum Mol Genet 2013 1.00
50 Hereditary breast cancer: ever more pieces to the polygenic puzzle. Hered Cancer Clin Pract 2013 0.99
51 Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia. Breast Cancer Res 2014 0.99
52 Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA. Hum Genet 2013 0.99
53 ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control. J Biol Chem 2011 0.98
54 Fanconi's anemia and clinical radiosensitivity report on two adult patients with locally advanced solid tumors treated by radiotherapy. Strahlenther Onkol 2003 0.98
55 Mutation analysis of the SLX4/FANCP gene in hereditary breast cancer. Breast Cancer Res Treat 2011 0.97
56 CHEK2 mutation and hereditary breast cancer. J Clin Oncol 2007 0.96
57 9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium. Cancer Epidemiol Biomarkers Prev 2012 0.95
58 Mutation analysis of BRCA1, BRCA2, PALB2 and BRD7 in a hospital-based series of German patients with triple-negative breast cancer. PLoS One 2012 0.94
59 Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma. Radiother Oncol 2012 0.94
60 A nonsense mutation (E1978X) in the ATM gene is associated with breast cancer. Breast Cancer Res Treat 2008 0.92
61 Missense variants in ATM in 26,101 breast cancer cases and 29,842 controls. Cancer Epidemiol Biomarkers Prev 2010 0.91
62 BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers. J Natl Cancer Inst 2015 0.90
63 Functional characterization connects individual patient mutations in ataxia telangiectasia mutated (ATM) with dysfunction of specific DNA double-strand break-repair signaling pathways. FASEB J 2011 0.90
64 Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk. Hum Genet 2014 0.89
65 Risk of ovarian cancer and the NF-κB pathway: genetic association with IL1A and TNFSF10. Cancer Res 2013 0.89
66 Association of chromosomal locus 8q24 and risk of prostate cancer: a hospital-based study of German patients treated with brachytherapy. Urol Oncol 2008 0.89
67 Apoptosis gene polymorphisms and risk of prostate cancer: a hospital-based study of German patients treated with brachytherapy. Urol Oncol 2011 0.89
68 ATM missense variant P1054R predisposes to prostate cancer. Radiother Oncol 2007 0.88
69 Neuregulin receptor ErbB4 functions as a transcriptional cofactor for the expression of surfactant protein B in the fetal lung. Am J Respir Cell Mol Biol 2011 0.88
70 Synergistic interaction of variants in CHEK2 and BRCA2 on breast cancer risk. Breast Cancer Res Treat 2008 0.87
71 Radiosensitivity of ataxia telangiectasia and Nijmegen breakage syndrome homozygotes and heterozygotes as determined by three-color FISH chromosome painting. Radiat Res 2002 0.86
72 Clinical radiosensitivity in breast cancer patients carrying pathogenic ATM gene mutations: no observation of increased radiation-induced acute or late effects. Radiother Oncol 2003 0.86
73 Mutations of the CFTR gene in Turkish patients with congenital bilateral absence of the vas deferens. Hum Reprod 2004 0.85
74 Resveratrol modulates DNA double-strand break repair pathways in an ATM/ATR-p53- and -Nbs1-dependent manner. Carcinogenesis 2008 0.85
75 New mutations in the ATM gene and clinical data of 25 AT patients. Neurogenetics 2011 0.85
76 SFRP1 CpG island methylation locus is associated with renal cell cancer susceptibility and disease recurrence. Epigenetics 2012 0.85
77 Multiplex measurement of cytokine/receptor gene polymorphisms and interaction between interleukin-10 (-1082) genotype and chorioamnionitis in extreme preterm delivery. J Soc Gynecol Investig 2006 0.84
78 Germline variation in TP53 regulatory network genes associates with breast cancer survival and treatment outcome. Int J Cancer 2012 0.82
79 Breast cancer in patients carrying a germ-line CHEK2 mutation: Outcome after breast conserving surgery and adjuvant radiotherapy. Radiother Oncol 2007 0.82
80 CYP2B6*6 is associated with increased breast cancer risk. Int J Cancer 2013 0.82
81 Polymorphisms in inflammation pathway genes and endometrial cancer risk. Cancer Epidemiol Biomarkers Prev 2012 0.81
82 IVS10-6T>G, an ancient ATM germline mutation linked with breast cancer. Hum Mutat 2003 0.81
83 NBS1 variant I171V and breast cancer risk. Breast Cancer Res Treat 2007 0.81
84 Prevalence of the BLM nonsense mutation, p.Q548X, in ovarian cancer patients from Central and Eastern Europe. Fam Cancer 2015 0.81
85 Prevalence of PALB2 mutation c.509_510delGA in unselected breast cancer patients from Central and Eastern Europe. Fam Cancer 2014 0.81
86 Neuregulin-1, the fetal endothelium, and brain damage in preterm newborns. Brain Behav Immun 2009 0.80
87 TOPBP1 missense variant Arg309Cys and breast cancer in a German hospital-based case-control study. J Negat Results Biomed 2010 0.79
88 Mutation analysis of the MDM4 gene in German breast cancer patients. BMC Cancer 2008 0.79
89 ATM gene mutations in former uranium miners of SDAG Wismut: a pilot study. Oncol Rep 2007 0.78
90 Polymorphisms in stromal genes and susceptibility to serous epithelial ovarian cancer: a report from the Ovarian Cancer Association Consortium. PLoS One 2011 0.78
91 Consortium analysis of gene and gene-folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk. Mol Nutr Food Res 2014 0.77
92 Breast cancer in female carriers of ATM gene alterations: outcome of adjuvant radiotherapy. Radiother Oncol 2004 0.77
93 Polymorphisms in genes of respiratory control and sudden infant death syndrome. Int J Legal Med 2015 0.77
94 TGFB1 gene polymorphism Leu10Pro (c.29T>C), prostate cancer incidence and quality of life in patients treated with brachytherapy. World J Urol 2008 0.76
95 Neuregulin-1 high-producer genotype is associated with a decreased risk of admission to the neonatal intensive care unit. Early Hum Dev 2010 0.76
96 Protective role of RAD50 on chromatin bridges during abnormal cytokinesis. FASEB J 2013 0.76
97 Novel ATM mutation in a German patient presenting as generalized dystonia without classical signs of ataxia-telangiectasia. J Neurol 2015 0.76
98 Double heterozygotes among breast cancer patients analyzed for BRCA1, CHEK2, ATM, NBN/NBS1, and BLM germ-line mutations. Breast Cancer Res Treat 2014 0.75
99 Prostate cancer risk is not altered by TP53AIP1 germline mutations in a German case-control series. PLoS One 2012 0.75
100 Mitochondrial dysfunction in a novel form of autosomal recessive ataxia. Mitochondrion 2012 0.75
101 The frequency of the BLM*p.Q548X (c.1642C > T) mutation in breast cancer patients from Russia. Breast Cancer Res Treat 2014 0.75