Platelet particle formation by anti GPIIIa49-66 Ab, Ca2+ ionophore A23187, and phorbol myristate acetate is induced by reactive oxygen species and inhibited by dexamethasone blockade of platelet phospholipase A2, 12-lipoxygenase, and NADPH oxidase.

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Published in Blood on June 01, 2007

Authors

Michael A Nardi1, Yelena Gor, Steven J Feinmark, Fang Xu, Simon Karpatkin

Author Affiliations

1: Department of Pediatrics, Center for Molecular Therapeutics, Columbia College of Physicians and Surgeons, New York, NY, USA.

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