Published in Anal Biochem on May 03, 2007
Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10. Biochem J (2009) 1.49
ADAM8 as a drug target in pancreatic cancer. Nat Commun (2015) 1.46
mGluR1/5-dependent long-term depression requires the regulated ectodomain cleavage of neuronal pentraxin NPR by TACE. Neuron (2008) 1.31
Proteolytic Activity Matrix Analysis (PrAMA) for simultaneous determination of multiple protease activities. Integr Biol (Camb) (2010) 1.20
Exosomes from human immunodeficiency virus type 1 (HIV-1)-infected cells license quiescent CD4+ T lymphocytes to replicate HIV-1 through a Nef- and ADAM17-dependent mechanism. J Virol (2014) 1.09
Gamma-secretase represents a therapeutic target for the treatment of invasive glioma mediated by the p75 neurotrophin receptor. PLoS Biol (2008) 1.03
Discovery of novel inhibitors of a disintegrin and metalloprotease 17 (ADAM17) using glycosylated and non-glycosylated substrates. J Biol Chem (2012) 1.02
GPER mediates estrogen-induced signaling and proliferation in human breast epithelial cells and normal and malignant breast. Horm Cancer (2014) 0.99
Bone marrow stromal cells enhance prostate cancer cell invasion through type I collagen in an MMP-12 dependent manner. Int J Cancer (2008) 0.95
Cyclic stretch stimulates vascular smooth muscle cell alignment by redox-dependent activation of Notch3. Am J Physiol Heart Circ Physiol (2010) 0.92
ADAM9 inhibition increases membrane activity of ADAM10 and controls α-secretase processing of amyloid precursor protein. J Biol Chem (2011) 0.92
Inhibition of matrix metalloproteinase activity prevents increases in myocardial tumor necrosis factor-alpha. J Mol Cell Cardiol (2010) 0.91
Transmural intestinal wall permeability in severe ischemia after enteral protease inhibition. PLoS One (2014) 0.89
Using fluorogenic peptide substrates to assay matrix metalloproteinases. Methods Mol Biol (2001) 0.88
Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2). Biochem J (2010) 0.87
A disintegrin and metalloproteinase-12 (ADAM12): function, roles in disease progression, and clinical implications. Biochim Biophys Acta (2013) 0.86
A substrate-free activity-based protein profiling screen for the discovery of selective PREPL inhibitors. J Am Chem Soc (2011) 0.86
Cell activation and HIV-1 replication in unstimulated CD4+ T lymphocytes ingesting exosomes from cells expressing defective HIV-1. Retrovirology (2014) 0.84
Loss of vps54 function leads to vesicle traffic impairment, protein mis-sorting and embryonic lethality. Int J Mol Sci (2013) 0.84
Quantitative analysis of gradient sensing: towards building predictive models of chemotaxis in cancer. Curr Opin Cell Biol (2012) 0.84
Activity of ADAM17 (a disintegrin and metalloprotease 17) is regulated by its noncatalytic domains and secondary structure of its substrates. J Biol Chem (2013) 0.84
Liver protective effect of ursodeoxycholic acid includes regulation of ADAM17 activity. BMC Gastroenterol (2013) 0.84
Effects of MMP inhibitors incorporated within dental adhesives. J Dent Res (2012) 0.84
Potential of fluorescent metalloproteinase substrates for cancer detection. Clin Biochem (2011) 0.83
Accelerated receptor shedding inhibits kidney injury molecule-1 (KIM-1)-mediated efferocytosis. Am J Physiol Renal Physiol (2014) 0.81
Metalloproteinase processing of HBEGF is a proximal event in the response of human aortic endothelial cells to oxidized phospholipids. Arterioscler Thromb Vasc Biol (2012) 0.81
Targeting autocrine HB-EGF signaling with specific ADAM12 inhibition using recombinant ADAM12 prodomain. Sci Rep (2015) 0.79
Reduced incidence and severity of experimental autoimmune arthritis in mice expressing catalytically inactive A disintegrin and metalloproteinase 8 (ADAM8). Clin Exp Immunol (2009) 0.78
Latent HIV-1 is activated by exosomes from cells infected with either replication-competent or defective HIV-1. Retrovirology (2015) 0.78
High Glucose Up-regulates ADAM17 through HIF-1α in Mesangial Cells. J Biol Chem (2015) 0.78
Glycosylation of a disintegrin and metalloprotease 17 affects its activity and inhibition. Anal Biochem (2013) 0.77
Regulation of amyloid precursor protein processing by serotonin signaling. PLoS One (2014) 0.77
Multiplexed protease assays using element-tagged substrates. Anal Biochem (2010) 0.77
The synthesis and application of Fmoc-Lys(5-Fam) building blocks. Biopolymers (2013) 0.75
Single Cell Proteolytic Assays to Investigate Cancer Clonal Heterogeneity and Cell Dynamics Using an Efficient Cell Loading Scheme. Sci Rep (2016) 0.75
ADAM15 Is Functionally Associated with the Metastatic Progression of Human Bladder Cancer. PLoS One (2016) 0.75
Glutamate-dependent ectodomain shedding of neuregulin-1 type II precursors in rat forebrain neurons. PLoS One (2017) 0.75
Fluorescent substrates useful as high-throughput screening tools for ADAM9. Comb Chem High Throughput Screen (2010) 0.87