Testing association for markers on the X chromosome.

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet (2012) 1.63

eXclusion: toward integrating the X chromosome in genome-wide association analyses. Am J Hum Genet (2013) 1.24

Testing for genetic association taking into account phenotypic information of relatives. BMC Proc (2009) 1.16

Comprehensive association analysis of candidate genes for generalized vitiligo supports XBP1, FOXP3, and TSLP. J Invest Dermatol (2010) 1.14

Sex chromosomes and genetic association studies. Genome Med (2009) 1.13

Accounting for eXentricities: analysis of the X chromosome in GWAS reveals X-linked genes implicated in autoimmune diseases. PLoS One (2014) 1.04

Association tests for X-chromosomal markers--a comparison of different test statistics. Hum Hered (2011) 0.97

Does genetic regulation of IgE begin in utero? Evidence from T(H)1/T(H)2 gene polymorphisms and cord blood total IgE. J Allergy Clin Immunol (2010) 0.96

XM: association testing on the X-chromosome in case-control samples with related individuals. Genet Epidemiol (2012) 0.93

X-chromosome genetic association test accounting for X-inactivation, skewed X-inactivation, and escape from X-inactivation. Genet Epidemiol (2014) 0.89

A sex-specific association of common variants of neuroligin genes (NLGN3 and NLGN4X) with autism spectrum disorders in a Chinese Han cohort. Behav Brain Funct (2011) 0.89

XWAS: A Software Toolset for Genetic Data Analysis and Association Studies of the X Chromosome. J Hered (2015) 0.87

An X chromosome-wide association analysis identifies variants in GPR174 as a risk factor for Graves' disease. J Med Genet (2013) 0.86

Likelihood Ratio Test for Excess Homozygosity at Marker Loci on X Chromosome. PLoS One (2015) 0.84

Modeling X Chromosome Data Using Random Forests: Conquering Sex Bias. Genet Epidemiol (2015) 0.81

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder. Hum Mol Genet (2016) 0.79

Testing for Hardy-Weinberg equilibrium at biallelic genetic markers on the X chromosome. Heredity (Edinb) (2016) 0.78

X-inactivation informs variance-based testing for X-linked association of a quantitative trait. BMC Genomics (2015) 0.78

Single nucleotide polymorphisms of the tenomodulin gene (TNMD) in age-related macular degeneration. Mol Vis (2009) 0.76

Genotype-Based Score Test for Association Testing in Families. Stat Biosci (2015) 0.75

FARVATX: Family-Based Rare Variant Association Test for X-Linked Genes. Genet Epidemiol (2016) 0.75

Statistical methods for genome-wide and sequencing association studies of complex traits in related samples. Curr Protoc Hum Genet (2015) 0.75

Simple strategies for haplotype analysis of the X chromosome with application to age-related macular degeneration. Eur J Hum Genet (2011) 0.75

Evaluating the Calibration and Power of Three Gene-Based Association Tests of Rare Variants for the X Chromosome. Genet Epidemiol (2015) 0.75

A Bayesian test for Hardy-Weinberg equilibrium of biallelic X-chromosomal markers. Heredity (Edinb) (2017) 0.75

Instability in X chromosome inactivation patterns in AMD: a new risk factor? Med Hypothesis Discov Innov Ophthalmol (2013) 0.75

Angiotensin-converting-enzyme inhibition in stable coronary artery disease. N Engl J Med (2004) 9.67

A pharmacogenetic versus a clinical algorithm for warfarin dosing. N Engl J Med (2013) 7.09

Mitral-valve repair versus replacement for severe ischemic mitral regurgitation. N Engl J Med (2013) 6.21

Surgical ablation of atrial fibrillation during mitral-valve surgery. N Engl J Med (2015) 4.77

Simultaneous phase and size control of upconversion nanocrystals through lanthanide doping. Nature (2010) 3.53

Two-Year Outcomes of Surgical Treatment of Severe Ischemic Mitral Regurgitation. N Engl J Med (2015) 3.11

Description of the data from the Collaborative Study on the Genetics of Alcoholism (COGA) and single-nucleotide polymorphism genotyping for Genetic Analysis Workshop 14. BMC Genet (2005) 3.04

Autologous haemopoietic stem-cell transplantation followed by allogeneic or autologous haemopoietic stem-cell transplantation in patients with multiple myeloma (BMT CTN 0102): a phase 3 biological assignment trial. Lancet Oncol (2011) 2.78

Risk of pancreatic cancer in relation to ABO blood group and hepatitis C virus infection in Korea: a case-control study. J Korean Med Sci (2013) 2.23

Prognosis of negative adenosine stress magnetic resonance in patients presenting to an emergency department with chest pain. J Am Coll Cardiol (2006) 2.08

Current evidence on the relationship between four polymorphisms in the matrix metalloproteinases (MMP) gene and breast cancer risk: a meta-analysis. Breast Cancer Res Treat (2010) 1.82

MicroRNA-181a sensitizes human malignant glioma U87MG cells to radiation by targeting Bcl-2. Oncol Rep (2010) 1.74

Transcriptional profiling of bone regeneration. Insight into the molecular complexity of wound repair. J Biol Chem (2002) 1.73

Statistical design of personalized medicine interventions: the Clarification of Optimal Anticoagulation through Genetics (COAG) trial. Trials (2010) 1.72

Wedge bronchoplastic lobectomy for non-small cell lung cancer as an alternative to sleeve lobectomy. J Thorac Cardiovasc Surg (2011) 1.53

Severity and timing of progression predict refractoriness to transarterial chemoembolization in hepatocellular carcinoma. J Gastroenterol Hepatol (2012) 1.48

Loss of parafibromin immunoreactivity is a distinguishing feature of parathyroid carcinoma. Clin Cancer Res (2004) 1.47

Reconstruction of chemically burned rat corneal surface by bone marrow-derived human mesenchymal stem cells. Stem Cells (2005) 1.46

Functional polymorphisms in CD166/ALCAM gene associated with increased risk for breast cancer in a Chinese population. Breast Cancer Res Treat (2011) 1.43

Angiographic changes in saphenous vein grafts are predictors of clinical outcomes. Am Heart J (2003) 1.41

Effect of indole-3-carbinol on ethanol-induced liver injury and acetaldehyde-stimulated hepatic stellate cells activation using precision-cut rat liver slices. Clin Exp Pharmacol Physiol (2010) 1.40

NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia. Antioxid Redox Signal (2012) 1.32

Evaluation of LOXL1 polymorphisms in exfoliation syndrome in a Chinese population. Mol Vis (2009) 1.28

Transcriptional repressor activating transcription factor 3 protects human umbilical vein endothelial cells from tumor necrosis factor-alpha-induced apoptosis through down-regulation of p53 transcription. J Biol Chem (2002) 1.24

Contribution of guanine nucleotide exchange factor Vav2 to hyperhomocysteinemic glomerulosclerosis in rats. Hypertension (2008) 1.23

Site-specific risk factors for colorectal cancer in a Korean population. PLoS One (2011) 1.21

[The chromosome number and gonadal structure of F9-F11 allotetraploid crucian-carp]. Yi Chuan Xue Bao (2003) 1.20

Calcium entry via TRPC6 mediates albumin overload-induced endoplasmic reticulum stress and apoptosis in podocytes. Cell Calcium (2011) 1.19

Prospective alpha allocation in the Clarification of Optimal Anticoagulation through Genetics (COAG) trial. Clin Trials (2010) 1.18

The t(1;3) breakpoint-spanning genes LSAMP and NORE1 are involved in clear cell renal cell carcinomas. Cancer Cell (2003) 1.18

Factors associated with overall survival in 1706 patients with nasopharyngeal carcinoma: significance of intensive neoadjuvant chemotherapy and radiation break. Radiother Oncol (2010) 1.17

High serum uric acid and increased risk of type 2 diabetes: a systemic review and meta-analysis of prospective cohort studies. PLoS One (2013) 1.17

Regulation of heterochromatin remodelling and myogenin expression during muscle differentiation by FAK interaction with MBD2. EMBO J (2009) 1.16

Recent advances in transition-metal catalyzed reactions using molecular oxygen as the oxidant. Chem Soc Rev (2012) 1.15

Rationale and design of the Clarification of Optimal Anticoagulation through Genetics trial. Am Heart J (2013) 1.12

Role of sphingolipid mediator ceramide in obesity and renal injury in mice fed a high-fat diet. J Pharmacol Exp Ther (2010) 1.12

STAT3 activation in response to growth factors or cytokines participates in retina precursor proliferation. Exp Eye Res (2005) 1.07

Can murine diabetic nephropathy be separated from superimposed acute renal failure? Kidney Int (2005) 1.05

Electron transport properties of atomic carbon nanowires between graphene electrodes. J Am Chem Soc (2010) 1.05

Heart failure as an endpoint in heart failure and non-heart failure cardiovascular clinical trials: the need for a consensus definition. Eur Heart J (2008) 1.05

Multi analyte profiling and variability of inflammatory markers in blood and induced sputum in patients with stable COPD. Respir Res (2010) 1.02

Membrane raft-lysosome redox signalling platforms in coronary endothelial dysfunction induced by adipokine visfatin. Cardiovasc Res (2010) 1.01

The formation of the polyploid hybrids from different subfamily fish crossings and its evolutionary significance. Genetics (2007) 1.01

Acid sphingomyelinase gene deficiency ameliorates the hyperhomocysteinemia-induced glomerular injury in mice. Am J Pathol (2011) 1.00

An alternatively spliced isoform of transcriptional repressor ATF3 and its induction by stress stimuli. Nucleic Acids Res (2002) 1.00

A novel reciprocal loop between microRNA-21 and TGFβRIII is involved in cardiac fibrosis. Int J Biochem Cell Biol (2012) 1.00

The TNF-alpha-238 polymorphism and cancer risk: a meta-analysis. PLoS One (2011) 0.99

Robust trend tests for genetic association in case-control studies using family data. BMC Genet (2005) 0.99

Organization and variation analysis of 5S rDNA in different ploidy-level hybrids of red crucian carp × topmouth culter. PLoS One (2012) 0.98

Adsorption of gas molecules on transition metal embedded graphene: a search for high-performance graphene-based catalysts and gas sensors. Nanotechnology (2011) 0.98

Regulation of CD2-associated protein influences podocyte endoplasmic reticulum stress-mediated apoptosis induced by albumin overload. Gene (2011) 0.97

High volumetric breast density predicts risk for breast cancer in postmenopausal, but not premenopausal, Korean Women. Ann Surg Oncol (2014) 0.97

Enrichment of human osteosarcoma stem cells based on hTERT transcriptional activity. Oncotarget (2013) 0.97

Joint analysis of binary and quantitative traits with data sharing and outcome-dependent sampling. Genet Epidemiol (2012) 0.96

Analysis of treatment outcomes of intraventricular chemotherapy in 105 patients for leptomeningeal carcinomatosis from non-small-cell lung cancer. J Thorac Oncol (2013) 0.95

Cloning and identification of a novel cDNA coding thioredoxin-related transmembrane protein 2. Biochem Genet (2003) 0.95

When to stop a clinical trial early for benefit: lessons learned and future approaches. Circ Heart Fail (2012) 0.95

Fixation behavior in primary open angle glaucoma at early and moderate stage assessed by the MicroPerimeter MP-1. J Glaucoma (2013) 0.95

A non-synonymous polymorphism Thr115Met in the EpCAM gene is associated with an increased risk of breast cancer in Chinese population. Breast Cancer Res Treat (2010) 0.95

Prognostic implications of genetic variants in advanced non-small cell lung cancer: a genome-wide association study. Carcinogenesis (2012) 0.94

Beta-asarone attenuates beta-amyloid-induced apoptosis through the inhibition of the activation of apoptosis signal-regulating kinase 1 in SH-SY5Y cells. Pharmazie (2011) 0.94

Functional NBS1 polymorphism is associated with occurrence and advanced disease status of nasopharyngeal carcinoma. Mol Carcinog (2011) 0.94

Visfatin-induced lipid raft redox signaling platforms and dysfunction in glomerular endothelial cells. Biochim Biophys Acta (2010) 0.94

Pearson's test, trend test, and MAX are all trend tests with different types of scores. Ann Hum Genet (2009) 0.93

Mild hypoxia-induced cardiomyocyte hypertrophy via up-regulation of HIF-1α-mediated TRPC signalling. J Cell Mol Med (2012) 0.93

Focal adhesion kinase mediates TGF-beta1-induced renal tubular epithelial-to-mesenchymal transition in vitro. Mol Cell Biochem (2010) 0.93

DNA vaccination with naked DNA encoding MCP-1 and RANTES protects against renal injury in adriamycin nephropathy. Kidney Int (2005) 0.93

Systematic review and meta-analysis of perioperative intravenous tranexamic acid use in spinal surgery. PLoS One (2013) 0.93

Role of NADPH oxidase-mediated reactive oxygen species in podocyte injury. Biomed Res Int (2013) 0.92

Risk for leptomeningeal seeding after resection for brain metastases: implication of tumor location with mode of resection. J Neurosurg (2012) 0.92

Color discrimination by patients with different types of light-filtering intraocular lenses. J Cataract Refract Surg (2010) 0.92

Low power IC design of the Wireless Monitoring System of the Orthopedic Implants. Conf Proc IEEE Eng Med Biol Soc (2007) 0.92

Polymorphisms of tumor necrosis factor-alpha and breast cancer risk: appraisal of a recent meta-analysis. Breast Cancer Res Treat (2010) 0.92

Designing comparative effectiveness trials of surgical ablation for atrial fibrillation: experience of the Cardiothoracic Surgical Trials Network. J Thorac Cardiovasc Surg (2011) 0.92

Worse outcome of sorafenib therapy associated with ascites and Child-Pugh score in advanced hepatocellular carcinoma. J Gastroenterol Hepatol (2013) 0.92

Nod-like receptor protein 1 inflammasome mediates neuron injury under high glucose. Mol Neurobiol (2013) 0.92

A robust test for two-stage design in genome-wide association studies. Biometrics (2009) 0.91

Biomarker-guided therapies in heart failure: a forum for unified strategies. J Card Fail (2013) 0.91

In vitro and in vivo evaluation of ribavirin and pleconaril antiviral activity against enterovirus 71 infection. Arch Virol (2012) 0.91

Effective nonenzymatic kinetic resolution of racemic m-nitro-substituted inherently chiral aminocalix[4]arenes. Org Lett (2008) 0.91

Polyploid organisms. Sci China Life Sci (2012) 0.91

Coexistence of diploid, triploid and tetraploid crucian carp (Carassius auratus) in natural waters. BMC Genet (2011) 0.90

TGFBR3, a potential negative regulator of TGF-β signaling, protects cardiac fibroblasts from hypoxia-induced apoptosis. J Cell Physiol (2011) 0.90

Conditional linkage and genome-wide association studies identify UGT1A1 as a major gene for anti-atherogenic serum bilirubin levels--the Framingham Heart Study. Atherosclerosis (2009) 0.90

Indoles from simple anilines and alkynes: palladium-catalyzed C-H activation using dioxygen as the oxidant. Angew Chem Int Ed Engl (2009) 0.90

Identifying FGA peptides as nasopharyngeal carcinoma-associated biomarkers by magnetic beads. J Cell Biochem (2012) 0.90

Reversal by growth hormone of homocysteine-induced epithelial-to-mesenchymal transition through membrane raft-redox signaling in podocytes. Cell Physiol Biochem (2011) 0.90

A new seed-train expansion method for recombinant mammalian cell lines. Cytotechnology (2002) 0.89

Exceptional chiral recognition of racemic carboxylic acids by calix[4]arenes bearing optically pure alpha,beta-amino alcohol groups. Org Lett (2004) 0.89

The clinical applications of curcumin: current state and the future. Curr Pharm Des (2013) 0.89

Synergistic enhancement of immunogenicity and protection in mice against Schistosoma japonicum with codon optimization and electroporation delivery of SjTPI DNA vaccines. Vaccine (2010) 0.88

Characterization of cell-banking parameters for the cryopreservation of mammalian cell lines in 100-mL cryobags. Biotechnol Prog (2010) 0.88

The two sides of cytokine signaling and glaucomatous optic neuropathy. J Ocul Biol Dis Infor (2009) 0.88

Establishment of the diploid gynogenetic hybrid clonal line of red crucian carp x common carp. Sci China C Life Sci (2007) 0.87

Triptolide alters histone H3K9 and H3K27 methylation state and induces G0/G1 arrest and caspase-dependent apoptosis in multiple myeloma in vitro. Toxicology (2009) 0.87

Identification and biochemical characterization of a novel transcription elongation factor, Elongin A3. J Biol Chem (2002) 0.87

Novel genetic markers derived from the DNA fragments of Sox genes. Mol Cell Probes (2009) 0.87

A retrospective survey of quality of reporting on randomized controlled trials of metformin for polycystic ovary syndrome. Trials (2014) 0.86