Published in Traffic on June 06, 2007
GILT is a critical host factor for Listeria monocytogenes infection. Nature (2008) 2.12
HMGB1 in health and disease. Mol Aspects Med (2014) 1.67
NADPH oxidase activity controls phagosomal proteolysis in macrophages through modulation of the lumenal redox environment of phagosomes. Proc Natl Acad Sci U S A (2010) 1.28
Labile disulfide bonds are common at the leucocyte cell surface. Open Biol (2011) 1.14
GILT accelerates autoimmunity to the melanoma antigen tyrosinase-related protein 1. J Immunol (2010) 1.05
Expanding roles for GILT in immunity. Curr Opin Immunol (2012) 1.01
Disulfide reduction in the endocytic pathway: immunological functions of gamma-interferon-inducible lysosomal thiol reductase. Antioxid Redox Signal (2011) 0.94
Interleukin-2 signalling is modulated by a labile disulfide bond in the CD132 chain of its receptor. Open Biol (2012) 0.91
MHC class II-restricted presentation of the major house dust mite allergen Der p 1 Is GILT-dependent: implications for allergic asthma. PLoS One (2013) 0.90
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Allosteric control of βII-tryptase by a redox active disulfide bond. J Biol Chem (2013) 0.83
Macrophage derived cystatin B/cathepsin B in HIV replication and neuropathogenesis. Curr HIV Res (2014) 0.80
Intracellular regulation of cross-presentation during dendritic cell maturation. PLoS One (2013) 0.78
Diverse cellular and organismal functions of the lysosomal thiol reductase GILT. Mol Immunol (2015) 0.75
Gamma-interferon-inducible, lysosome/endosome-localized thiolreductase, GILT, has anti-retroviral activity and its expression is counteracted by HIV-1. Oncotarget (2016) 0.75
Reduction-responsive polymeric micelles and vesicles for triggered intracellular drug release. Antioxid Redox Signal (2014) 0.75
Characterization and expression of gamma-interferon-inducible lysosomal thiol reductase (GILT) gene in rainbow trout (Oncorhynchus mykiss) with implications for GILT in innate immune response. Immunogenetics (2013) 0.75
A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules. Blood (2005) 4.64
Human macrophages accumulate HIV-1 particles in MHC II compartments. Traffic (2002) 3.39
The interferon-inducible protein viperin inhibits influenza virus release by perturbing lipid rafts. Cell Host Microbe (2007) 3.11
A role for the endoplasmic reticulum protein retrotranslocation machinery during crosspresentation by dendritic cells. Immunity (2006) 3.00
Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D. Nat Immunol (2002) 2.87
Pathways of antigen processing. Annu Rev Immunol (2013) 2.82
GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals. Science (2012) 2.69
Human cytomegalovirus directly induces the antiviral protein viperin to enhance infectivity. Science (2011) 2.67
Insights into MHC class I peptide loading from the structure of the tapasin-ERp57 thiol oxidoreductase heterodimer. Immunity (2009) 2.46
Herpes simplex virus evades natural killer T cell recognition by suppressing CD1d recycling. Nat Immunol (2006) 2.28
Access of soluble antigens to the endoplasmic reticulum can explain cross-presentation by dendritic cells. Nat Immunol (2004) 2.18
GILT is a critical host factor for Listeria monocytogenes infection. Nature (2008) 2.12
Saposins facilitate CD1d-restricted presentation of an exogenous lipid antigen to T cells. Nat Immunol (2004) 2.09
Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens. Proc Natl Acad Sci U S A (2003) 2.09
Selective loading of high-affinity peptides onto major histocompatibility complex class I molecules by the tapasin-ERp57 heterodimer. Nat Immunol (2007) 2.03
Kinetics and cellular site of glycolipid loading control the outcome of natural killer T cell activation. Immunity (2009) 2.00
Cellular mechanisms governing cross-presentation of exogenous antigens. Nat Immunol (2004) 1.97
Enhanced and prolonged cross-presentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticles. Immunology (2006) 1.92
The quality control of MHC class I peptide loading. Curr Opin Cell Biol (2008) 1.91
Regulation of MHC class I assembly and peptide binding. Annu Rev Cell Dev Biol (2008) 1.82
Disulfide bond isomerization and the assembly of MHC class I-peptide complexes. Immunity (2002) 1.76
Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors. Proc Natl Acad Sci U S A (2004) 1.76
Contrasting functions of calreticulin and calnexin in glycoprotein folding and ER quality control. Mol Cell (2004) 1.62
The antiviral protein, viperin, localizes to lipid droplets via its N-terminal amphipathic alpha-helix. Proc Natl Acad Sci U S A (2009) 1.55
Tapasin and ERp57 form a stable disulfide-linked dimer within the MHC class I peptide-loading complex. EMBO J (2005) 1.47
Viral and bacterial infections induce expression of multiple NK cell receptors in responding CD8(+) T cells. J Immunol (2002) 1.44
Natural lipid ligands associated with human CD1d targeted to different subcellular compartments. J Immunol (2009) 1.44
Involvement of the endoplasmic reticulum in peroxisome formation. Mol Biol Cell (2003) 1.41
Innate immune surveillance of spontaneous B cell lymphomas by natural killer cells and gammadelta T cells. J Exp Med (2004) 1.40
Implications of CD94 deficiency and monoallelic NKG2A expression for natural killer cell development and repertoire formation. Proc Natl Acad Sci U S A (2002) 1.38
Absence of gamma-interferon-inducible lysosomal thiol reductase in melanomas disrupts T cell recognition of select immunodominant epitopes. J Exp Med (2002) 1.38
Rapid pathogen-induced apoptosis: a mechanism used by dendritic cells to limit intracellular replication of Legionella pneumophila. PLoS Pathog (2009) 1.37
Regulation of intracellular trafficking of human CD1d by association with MHC class II molecules. EMBO J (2002) 1.35
The N-terminal amphipathic alpha-helix of viperin mediates localization to the cytosolic face of the endoplasmic reticulum and inhibits protein secretion. J Biol Chem (2008) 1.34
Regulation of MHC class I transport in human dendritic cells and the dendritic-like cell line KG-1. J Immunol (2003) 1.33
Defective cross-presentation of viral antigens in GILT-free mice. Science (2010) 1.30
Saposin B is the dominant saposin that facilitates lipid binding to human CD1d molecules. Proc Natl Acad Sci U S A (2007) 1.29
Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity. Proc Natl Acad Sci U S A (2009) 1.24
The interferon-inducible gene viperin restricts West Nile virus pathogenesis. J Virol (2011) 1.20
C19orf48 encodes a minor histocompatibility antigen recognized by CD8+ cytotoxic T cells from renal cell carcinoma patients. Clin Cancer Res (2008) 1.20
Tapasin is a facilitator, not an editor, of class I MHC peptide binding. J Immunol (2003) 1.19
Cathepsin S controls MHC class II-mediated antigen presentation by epithelial cells in vivo. J Immunol (2005) 1.15
Viperin: a multifunctional, interferon-inducible protein that regulates virus replication. Cell Host Microbe (2011) 1.14
Labile disulfide bonds are common at the leucocyte cell surface. Open Biol (2011) 1.14
A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation. Cell (2011) 1.14
Calnexin, calreticulin, and ERp57 cooperate in disulfide bond formation in human CD1d heavy chain. J Biol Chem (2002) 1.13
Lipid-protein interactions: biosynthetic assembly of CD1 with lipids in the endoplasmic reticulum is evolutionarily conserved. Proc Natl Acad Sci U S A (2004) 1.13
The redox activity of ERp57 is not essential for its functions in MHC class I peptide loading. Proc Natl Acad Sci U S A (2008) 1.11
Functional requirements for the lysosomal thiol reductase GILT in MHC class II-restricted antigen processing. J Immunol (2006) 1.11
Golgi targeting of human guanylate-binding protein-1 requires nucleotide binding, isoprenylation, and an IFN-gamma-inducible cofactor. Proc Natl Acad Sci U S A (2005) 1.06
Target peptide sequence within infectious human immunodeficiency virus type 1 does not ensure envelope-specific T-helper cell reactivation: influences of cysteine protease and gamma interferon-induced thiol reductase activities. Clin Vaccine Immunol (2008) 1.05
Human mast cells produce and release the cytotoxic lymphocyte associated protease granzyme B upon activation. Mol Immunol (2007) 1.05
GILT accelerates autoimmunity to the melanoma antigen tyrosinase-related protein 1. J Immunol (2010) 1.05
Receptor-mediated phagocytosis elicits cross-presentation in nonprofessional antigen-presenting cells. Proc Natl Acad Sci U S A (2009) 1.05
Severe tryptophan starvation blocks onset of conventional persistence and reduces reactivation of Chlamydia trachomatis. Infect Immun (2007) 1.04
Recent developments in MHC-class-I-mediated antigen presentation. Curr Opin Immunol (2004) 1.03
Hsp90-mediated cytosolic refolding of exogenous proteins internalized by dendritic cells. EMBO J (2007) 1.02
Proteasomes and proteasome activator 200 kDa (PA200) accumulate on chromatin in response to ionizing radiation. Radiat Res (2007) 1.02
CDK8-mediated STAT1-S727 phosphorylation restrains NK cell cytotoxicity and tumor surveillance. Cell Rep (2013) 1.02
Herpes simplex virus 1 glycoprotein B and US3 collaborate to inhibit CD1d antigen presentation and NKT cell function. J Virol (2011) 1.01
Expanding roles for GILT in immunity. Curr Opin Immunol (2012) 1.01
Regulation of NO synthesis, local inflammation, and innate immunity to pathogens by BET family proteins. Mol Cell Biol (2013) 1.00
Viperin is required for optimal Th2 responses and T-cell receptor-mediated activation of NF-kappaB and AP-1. Blood (2008) 1.00
Exposure of the promonocytic cell line THP-1 to Escherichia coli induces IFN-gamma-inducible lysosomal thiol reductase expression by inflammatory cytokines. J Immunol (2006) 1.00
Differential requirements for endosomal reduction in the presentation of two H2-E(d)-restricted epitopes from influenza hemagglutinin. J Immunol (2004) 0.98
Endoplasmic reticulum export, subcellular distribution, and fibril formation by Pmel17 require an intact N-terminal domain junction. J Biol Chem (2010) 0.97
Identification of specific glycoforms of major histocompatibility complex class I heavy chains suggests that class I peptide loading is an adaptation of the quality control pathway involving calreticulin and ERp57. J Biol Chem (2002) 0.96
Major histocompatibility complex class I molecules expressed with monoglucosylated N-linked glycans bind calreticulin independently of their assembly status. J Biol Chem (2004) 0.95
Proprotein convertases process Pmel17 during secretion. J Biol Chem (2011) 0.94
Human CD1d knock-in mouse model demonstrates potent antitumor potential of human CD1d-restricted invariant natural killer T cells. Proc Natl Acad Sci U S A (2013) 0.94
Disulfide reduction in the endocytic pathway: immunological functions of gamma-interferon-inducible lysosomal thiol reductase. Antioxid Redox Signal (2011) 0.94
TLR and nucleotide-binding oligomerization domain-like receptor signals differentially regulate exogenous antigen presentation. J Immunol (2011) 0.93
Intracellular events regulating cross-presentation. Front Immunol (2012) 0.93
Characterization of the TGN exit signal of the human mannose 6-phosphate uncovering enzyme. J Cell Sci (2005) 0.93
Both TLR2 and TRIF contribute to interferon-β production during Listeria infection. PLoS One (2012) 0.92
An N-linked glycan modulates the interaction between the CD1d heavy chain and beta 2-microglobulin. J Biol Chem (2006) 0.92
Thiol oxidation and reduction in major histocompatibility complex class I-restricted antigen processing and presentation. Methods Enzymol (2002) 0.92
Critical residues in the PMEL/Pmel17 N-terminus direct the hierarchical assembly of melanosomal fibrils. Mol Biol Cell (2013) 0.91
Viperin regulates cellular lipid metabolism during human cytomegalovirus infection. PLoS Pathog (2013) 0.91
Interleukin-2 signalling is modulated by a labile disulfide bond in the CD132 chain of its receptor. Open Biol (2012) 0.91
Contribution of a TANK-binding kinase 1-interferon (IFN) regulatory factor 7 pathway to IFN-γ-induced gene expression. Mol Cell Biol (2012) 0.91
Deglycosylation-dependent fluorescent proteins provide unique tools for the study of ER-associated degradation. Proc Natl Acad Sci U S A (2013) 0.90
Stoichiometric tapasin interactions in the catalysis of major histocompatibility complex class I molecule assembly. Immunology (2005) 0.90
MHC class II-restricted presentation of the major house dust mite allergen Der p 1 Is GILT-dependent: implications for allergic asthma. PLoS One (2013) 0.90
Essential glycan-dependent interactions optimize MHC class I peptide loading. Proc Natl Acad Sci U S A (2011) 0.90
Viperin is highly induced in neutrophils and macrophages during acute and chronic lymphocytic choriomeningitis virus infection. J Immunol (2010) 0.90
Dynamics of major histocompatibility complex class I association with the human peptide-loading complex. J Biol Chem (2012) 0.88
Viperin mRNA is a novel target for the human RNase MRP/RNase P endoribonuclease. Cell Mol Life Sci (2010) 0.88
A switch in pathogenic mechanism in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in IFN-γ-inducible lysosomal thiol reductase-free mice. J Immunol (2012) 0.88
Aggregate formation by ERp57-deficient MHC class I peptide-loading complexes. Traffic (2007) 0.88
A role for UDP-glucose glycoprotein glucosyltransferase in expression and quality control of MHC class I molecules. Proc Natl Acad Sci U S A (2011) 0.87
Role for lysosomal phospholipase A2 in iNKT cell-mediated CD1d recognition. Proc Natl Acad Sci U S A (2013) 0.85
Role of the C-terminal propeptide in the activity and maturation of gamma -interferon-inducible lysosomal thiol reductase (GILT). Proc Natl Acad Sci U S A (2002) 0.84
The role of NKG2D signaling in inhibition of cytotoxic T-lymphocyte lysis by the Murine cytomegalovirus immunoevasin m152/gp40. J Virol (2007) 0.83
Functional significance of tapasin membrane association and disulfide linkage to ERp57 in MHC class I presentation. Eur J Immunol (2009) 0.83
3-D Structure of multilaminar lysosomes in antigen presenting cells reveals trapping of MHC II on the internal membranes. Traffic (2004) 0.83
Role of individual domains and identification of internal gap in human guanylate binding protein-1. J Mol Biol (2009) 0.83
Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation. Proc Natl Acad Sci U S A (2013) 0.83
Identification of an alternate splice form of tapasin in human melanoma. Hum Immunol (2010) 0.83
Sibling rivalry: competition between MHC class II family members inhibits immunity. Nat Struct Mol Biol (2013) 0.83