PubRank

Hans P Merkle

Author PubWeight™ 70.93‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Microencapsulation by solvent extraction/evaporation: reviewing the state of the art of microsphere preparation process technology. J Control Release 2005 2.17
2 Control of in vitro tissue-engineered bone-like structures using human mesenchymal stem cells and porous silk scaffolds. Biomaterials 2006 1.56
3 Cartilage-like tissue engineering using silk scaffolds and mesenchymal stem cells. Tissue Eng 2006 1.45
4 Silk fibroin as a vehicle for drug delivery applications. J Control Release 2010 1.40
5 Silk fibroin spheres as a platform for controlled drug delivery. J Control Release 2008 1.35
6 Localized delivery of growth factors for bone repair. Eur J Pharm Biopharm 2004 1.30
7 Nerve conduits and growth factor delivery in peripheral nerve repair. J Peripher Nerv Syst 2007 1.29
8 PEGylation as a tool for the biomedical engineering of surface modified microparticles. J Pharm Sci 2008 1.23
9 Osteogenesis by human mesenchymal stem cells cultured on silk biomaterials: comparison of adenovirus mediated gene transfer and protein delivery of BMP-2. Biomaterials 2006 1.22
10 Formulation aspects of biodegradable polymeric microspheres for antigen delivery. Adv Drug Deliv Rev 2005 1.22
11 On the biomedical promise of cell penetrating peptides: limits versus prospects. J Pharm Sci 2008 1.18
12 Silk fibroin matrices for the controlled release of nerve growth factor (NGF). Biomaterials 2007 1.17
13 Insulin-like growth factor I releasing silk fibroin scaffolds induce chondrogenic differentiation of human mesenchymal stem cells. J Control Release 2007 1.12
14 Transfer of lipophilic markers from PLGA and polystyrene nanoparticles to caco-2 monolayers mimics particle uptake. Pharm Res 2002 1.12
15 Localized insulin-like growth factor I delivery to enhance new bone formation. Bone 2003 1.12
16 Chances and pitfalls of cell penetrating peptides for cellular drug delivery. Eur J Pharm Biopharm 2004 1.09
17 Decoding the entry of two novel cell-penetrating peptides in HeLa cells: lipid raft-mediated endocytosis and endosomal escape. Biochemistry 2005 1.08
18 Transport of surface-modified nanoparticles through cell monolayers. Chembiochem 2005 1.08
19 Encapsulation of proteins and peptides into biodegradable poly(D,L-lactide-co-glycolide) microspheres prolongs and enhances antigen presentation by human dendritic cells. Vaccine 2005 1.05
20 Optimization strategies for electrospun silk fibroin tissue engineering scaffolds. Biomaterials 2009 1.03
21 Phagocytosis and phagosomal fate of surface-modified microparticles in dendritic cells and macrophages. Pharm Res 2003 1.03
22 Particulate formulations for the delivery of poly(I:C) as vaccine adjuvant. Adv Drug Deliv Rev 2013 1.02
23 Metabolic cleavage of cell-penetrating peptides in contact with epithelial models: human calcitonin (hCT)-derived peptides, Tat(47-57) and penetratin(43-58). Biochem J 2004 0.98
24 Microporous silk fibroin scaffolds embedding PLGA microparticles for controlled growth factor delivery in tissue engineering. Biomaterials 2009 0.98
25 Ligand-specific targeting of microspheres to phagocytes by surface modification with poly(L-lysine)-grafted poly(ethylene glycol) conjugate. Pharm Res 2003 0.97
26 Evaluation of pH-dependent membrane-disruptive properties of poly(acrylic acid) derived polymers. Eur J Pharm Biopharm 2003 0.97
27 Concomitant delivery of a CTL-restricted peptide antigen and CpG ODN by PLGA microparticles induces cellular immune response. J Drug Target 2009 0.97
28 Amphiphilic dendrimers: novel self-assembling vectors for efficient gene delivery. Angew Chem Int Ed Engl 2003 0.96
29 Differentiation restricted endocytosis of cell penetrating peptides in MDCK cells corresponds with activities of Rho-GTPases. Pharm Res 2007 0.95
30 Silk fibroin/hyaluronan scaffolds for human mesenchymal stem cell culture in tissue engineering. Biomaterials 2009 0.95
31 Electrospun matrices for localized drug delivery: current technologies and selected biomedical applications. Eur J Pharm Biopharm 2012 0.94
32 DNA-loaded biodegradable microparticles as vaccine delivery systems and their interaction with dendritic cells. Adv Drug Deliv Rev 2005 0.94
33 The cell penetrating peptides pVEC and W2-pVEC induce transformation of gel phase domains in phospholipid bilayers without affecting their integrity. Biochemistry 2006 0.94
34 Cotton wool-like nanocomposite biomaterials prepared by electrospinning: in vitro bioactivity and osteogenic differentiation of human mesenchymal stem cells. J Biomed Mater Res B Appl Biomater 2008 0.93
35 Non-invasive time-lapsed monitoring and quantification of engineered bone-like tissue. Ann Biomed Eng 2007 0.91
36 The support of adenosine release from adenosine kinase deficient ES cells by silk substrates. Biomaterials 2006 0.90
37 Microparticle-mediated transfection of non-phagocytic cells in vitro. J Drug Target 2002 0.90
38 The use of sulfonated silk fibroin derivatives to control binding, delivery and potency of FGF-2 in tissue regeneration. Biomaterials 2009 0.88
39 Phenotype and functional analysis of human monocyte-derived dendritic cells loaded with biodegradable poly(lactide-co-glycolide) microspheres for immunotherapy. J Immunol Methods 2004 0.88
40 Biopolymer-based growth factor delivery for tissue repair: from natural concepts to engineered systems. Tissue Eng Part B Rev 2009 0.87
41 Remodeling of tissue-engineered bone structures in vivo. Eur J Pharm Biopharm 2013 0.87
42 Mannose-based molecular patterns on stealth microspheres for receptor-specific targeting of human antigen-presenting cells. Langmuir 2008 0.86
43 Metabolic cleavage and translocation efficiency of selected cell penetrating peptides: a comparative study with epithelial cell cultures. AAPS J 2008 0.86
44 Controlled nerve growth factor release from multi-ply alginate/chitosan-based nerve conduits. Eur J Pharm Biopharm 2008 0.86
45 The preservation of phenotype and functionality of dendritic cells upon phagocytosis of polyelectrolyte-coated PLGA microparticles. Biomaterials 2006 0.85
46 One-step preparation of polyelectrolyte-coated PLGA microparticles and their functionalization with model ligands. J Control Release 2005 0.85
47 Improved stimulation of human dendritic cells by receptor engagement with surface-modified microparticles. J Drug Target 2003 0.85
48 Continuous contact- and contamination-free ultrasonic emulsification-a useful tool for pharmaceutical development and production. Ultrason Sonochem 2004 0.85
49 Competitive adsorption of serum proteins at microparticles affects phagocytosis by dendritic cells. Biomaterials 2003 0.84
50 Cellular uptake but low permeation of human calcitonin-derived cell penetrating peptides and Tat(47-57) through well-differentiated epithelial models. Pharm Res 2004 0.84
51 A protective allergy vaccine based on CpG- and protamine-containing PLGA microparticles. Pharm Res 2007 0.82
52 Insulin-like growth factor I-releasing alginate-tricalciumphosphate composites for bone regeneration. Pharm Res 2005 0.81
53 Reviewing biophysical and cell biological methodologies in cell-penetrating peptide (CPP) research. Crit Rev Ther Drug Carrier Syst 2007 0.81
54 Evaluation of cationic solid lipid microparticles as synthetic carriers for the targeted delivery of macromolecules to phagocytic antigen-presenting cells. Biomaterials 2002 0.81
55 Membrane surface-associated helices promote lipid interactions and cellular uptake of human calcitonin-derived cell penetrating peptides. Biophys J 2005 0.80
56 Hydrogel nerve conduits produced from alginate/chitosan complexes. J Biomed Mater Res A 2007 0.80
57 An experimental divalent vaccine based on biodegradable microspheres induces protective immunity against tetanus and diphtheria. J Pharm Sci 2003 0.80
58 Composition and surface charge of DNA-loaded microparticles determine maturation and cytokine secretion in human dendritic cells. Pharm Res 2004 0.80
59 On technological and immunological benefits of multivalent single-injection microsphere vaccines. Pharm Res 2002 0.80
60 Bilayer interaction and localization of cell penetrating peptides with model membranes: a comparative study of a human calcitonin (hCT)-derived peptide with pVEC and pAntp(43-58). Biochim Biophys Acta 2005 0.79
61 Immobilisation of GM-CSF onto particulate vaccine carrier systems. Int J Pharm 2004 0.79
62 Design and validation of a novel bioreactor principle to combine online micro-computed tomography monitoring and mechanical loading in bone tissue engineering. Rev Sci Instrum 2010 0.79
63 Cellular internalization of human calcitonin derived peptides in MDCK monolayers: a comparative study with Tat(47-57) and penetratin(43-58). Pharm Res 2004 0.79
64 Cellular internalization of enhanced green fluorescent protein ligated to a human calcitonin-based carrier peptide. Chembiochem 2002 0.79
65 A crystal clear solution for insulin delivery. Nat Biotechnol 2002 0.79
66 Tuning the immune response of dendritic cells to surface-assembled poly(I:C) on microspheres through synergistic interactions between phagocytic and TLR3 signaling. Biomaterials 2011 0.78
67 Biocompatibility and osteoconduction of macroporous silk fibroin implants in cortical defects in sheep. Eur J Pharm Biopharm 2013 0.78
68 Transfection of a mouse dendritic cell line by plasmid DNA-loaded PLGA microparticles in vitro. Eur J Pharm Biopharm 2004 0.78
69 Stable stealth function for hollow polyelectrolyte microcapsules through a poly(ethylene glycol) grafted polyelectrolyte adlayer. Biomacromolecules 2007 0.77
70 Impact of IGF-I release kinetics on bone healing: a preliminary study in sheep. Eur J Pharm Biopharm 2013 0.77
71 The effect of hyaluronic acid on silk fibroin conformation. Biomaterials 2007 0.77
72 Flow-through ultrasonic emulsification combined with static micromixing for aseptic production of microspheres by solvent extraction. Eur J Pharm Biopharm 2005 0.76
73 Phagocytosis of synthetic particulate vaccine delivery systems to program dendritic cells. Expert Rev Vaccines 2002 0.76
74 Phagocytosis of poly(L-lysine)-graft-poly(ethylene glycol) coated microspheres by antigen presenting cells: Impact of grafting ratio and poly(ethylene glycol) chain length on cellular recognition. Biointerphases 2006 0.76
75 Dendronised block copolymers as potential vectors for gene transfection. Org Biomol Chem 2008 0.75
76 Modulation of allergic responses in mice by using biodegradable poly(lactide-co-glycolide) microspheres. J Allergy Clin Immunol 2004 0.75
77 Effects of structural modification on gene transfection and self-assembling properties of amphiphilic dendrimers. Org Biomol Chem 2006 0.75
78 Compromised integrity of excised porcine intestinal epithelium obtained from the abattoir affects the outcome of in vitro particle uptake studies. Eur J Pharm Sci 2002 0.75
79 In vitro assessment of intestinal IGF-I stability. J Pharm Sci 2002 0.75
80 Surface assembly of poly(I:C) on PEGylated microspheres to shield from adverse interactions with fibroblasts. J Control Release 2012 0.75