Published in Biochemistry on June 16, 2007
Protein export according to schedule: architecture, assembly, and regulation of type III secretion systems from plant- and animal-pathogenic bacteria. Microbiol Mol Biol Rev (2012) 1.92
Liposomes recruit IpaC to the Shigella flexneri type III secretion apparatus needle as a final step in secretion induction. Infect Immun (2009) 1.45
Broadly protective Shigella vaccine based on type III secretion apparatus proteins. Infect Immun (2011) 1.41
IpaB-IpgC interaction defines binding motif for type III secretion translocator. Proc Natl Acad Sci U S A (2009) 1.37
Induction and relaxation dynamics of the regulatory network controlling the type III secretion system encoded within Salmonella pathogenicity island 1. J Mol Biol (2007) 1.16
Tetratricopeptide repeat motifs in the world of bacterial pathogens: role in virulence mechanisms. Infect Immun (2012) 1.08
Characterization of a novel fusion protein from IpaB and IpaD of Shigella spp. and its potential as a pan-Shigella vaccine. Infect Immun (2013) 1.02
The chaperone IpgC copurifies with the virulence regulator MxiE. J Bacteriol (2008) 1.01
Oligomeric states of the Shigella translocator protein IpaB provide structural insights into formation of the type III secretion translocon. Protein Sci (2013) 0.99
Binding affects the tertiary and quaternary structures of the Shigella translocator protein IpaB and its chaperone IpgC. Biochemistry (2012) 0.99
Spontaneous formation of IpaB ion channels in host cell membranes reveals how Shigella induces pyroptosis in macrophages. Cell Death Dis (2012) 0.97
Antigen-specific IgA B memory cell responses to Shigella antigens elicited in volunteers immunized with live attenuated Shigella flexneri 2a oral vaccine candidates. Clin Immunol (2011) 0.97
Evidence for alternative quaternary structure in a bacterial Type III secretion system chaperone. BMC Struct Biol (2010) 0.92
The C-terminus of IpaC is required for effector activities related to Shigella invasion of host cells. Microb Pathog (2008) 0.90
Efficient isolation of Pseudomonas aeruginosa type III secretion translocators and assembly of heteromeric transmembrane pores in model membranes. Biochemistry (2011) 0.88
Shigella IpaB and IpaD displayed on L. lactis bacterium-like particles induce protective immunity in adult and infant mice. Immunol Cell Biol (2015) 0.86
Crystal structure of the Yersinia enterocolitica type III secretion chaperone SycD in complex with a peptide of the minor translocator YopD. BMC Struct Biol (2012) 0.85
Förster resonance energy transfer (FRET) as a tool for dissecting the molecular mechanisms for maturation of the Shigella type III secretion needle tip complex. Int J Mol Sci (2012) 0.84
Dimerization of the Pseudomonas aeruginosa translocator chaperone PcrH is required for stability, not function. J Bacteriol (2013) 0.80
Influence of oligomerization state on the structural properties of invasion plasmid antigen B from Shigella flexneri in the presence and absence of phospholipid membranes. Proteins (2014) 0.79
Studies of the conformational stability of invasion plasmid antigen B from Shigella. Protein Sci (2013) 0.79
The Many Faces of IpaB. Front Cell Infect Microbiol (2016) 0.77
Steps for Shigella Gatekeeper MxiC Function in Hierarchical Type III Secretion Regulation. J Biol Chem (2016) 0.75
The Type III Secretion System-Related CPn0809 from Chlamydia pneumoniae. PLoS One (2016) 0.75
Acylation of the Type 3 Secretion System Translocon Using a Dedicated Acyl Carrier Protein. PLoS Genet (2017) 0.75
EseE of Edwardsiella tarda Augments Secretion of Translocon Protein EseC and Expression of the escC-eseE Operon. Infect Immun (2016) 0.75
Detergent Isolation Stabilizes and Activates the Shigella Type III Secretion System Translocator Protein IpaC. J Pharm Sci (2016) 0.75
A Late Triassic dinosauromorph assemblage from New Mexico and the rise of dinosaurs. Science (2007) 3.39
A complete skeleton of a Late Triassic saurischian and the early evolution of dinosaurs. Science (2009) 3.13
Best practices for justifying fossil calibrations. Syst Biol (2011) 2.51
Overlooking subvisible particles in therapeutic protein products: gaps that may compromise product quality. J Pharm Sci (2009) 2.36
IpaD localizes to the tip of the type III secretion system needle of Shigella flexneri. Infect Immun (2006) 2.24
Molecular model of a type III secretion system needle: Implications for host-cell sensing. Proc Natl Acad Sci U S A (2006) 2.16
A longirostrine tyrannosauroid from the Early Cretaceous of China. Proc Biol Sci (2009) 2.03
The needle component of the type III secreton of Shigella regulates the activity of the secretion apparatus. J Biol Chem (2005) 1.92
Nanotechnology in vaccine delivery. Adv Drug Deliv Rev (2008) 1.91
Barriers to nonviral gene delivery. J Pharm Sci (2003) 1.77
Bile salts stimulate recruitment of IpaB to the Shigella flexneri surface, where it colocalizes with IpaD at the tip of the type III secretion needle. Infect Immun (2007) 1.75
IpaD of Shigella flexneri is independently required for regulation of Ipa protein secretion and efficient insertion of IpaB and IpaC into host membranes. Infect Immun (2005) 1.73
Self-chaperoning of the type III secretion system needle tip proteins IpaD and BipD. J Biol Chem (2006) 1.72
SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34. J Cell Biol (2008) 1.64
Solution structure of monomeric BsaL, the type III secretion needle protein of Burkholderia pseudomallei. J Mol Biol (2006) 1.55
Label-free quantitation of phosphopeptide changes during rat sperm capacitation. J Proteome Res (2010) 1.49
Liposomes recruit IpaC to the Shigella flexneri type III secretion apparatus needle as a final step in secretion induction. Infect Immun (2009) 1.45
Biophysical characterization of PEI/DNA complexes. J Pharm Sci (2003) 1.44
Broadly protective Shigella vaccine based on type III secretion apparatus proteins. Infect Immun (2011) 1.41
Conformational stability and disassembly of Norwalk virus-like particles. Effect of pH and temperature. J Biol Chem (2006) 1.41
Deoxycholate interacts with IpaD of Shigella flexneri in inducing the recruitment of IpaB to the type III secretion apparatus needle tip. J Biol Chem (2008) 1.40
Rethinking the phylogeny of scleractinian corals: a review of morphological and molecular data. Integr Comp Biol (2010) 1.35
Silicone oil induced aggregation of proteins. J Pharm Sci (2005) 1.32
Helical packing of needles from functionally altered Shigella type III secretion systems. J Mol Biol (2005) 1.31
Deletion in the Shigella enterotoxin genes further attenuates Shigella flexneri 2a bearing guanine auxotrophy in a phase 1 trial of CVD 1204 and CVD 1208. J Infect Dis (2004) 1.31
Structure/function relationships of polyamidoamine/DNA dendrimers as gene delivery vehicles. J Pharm Sci (2005) 1.27
Polyanions and the proteome. Mol Cell Proteomics (2004) 1.24
Derivative absorbance spectroscopy and protein phase diagrams as tools for comprehensive protein characterization: a bGCSF case study. J Pharm Sci (2003) 1.21
The structures of coiled-coil domains from type III secretion system translocators reveal homology to pore-forming toxins. J Mol Biol (2012) 1.20
Effects of adsorption to aluminum salt adjuvants on the structure and stability of model protein antigens. J Biol Chem (2005) 1.19
Protein-excipient interactions: mechanisms and biophysical characterization applied to protein formulation development. Adv Drug Deliv Rev (2011) 1.19
Thermal stability of vaccines. J Pharm Sci (2003) 1.17
Structural stability of adenovirus type 5. J Pharm Sci (2003) 1.17
Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: essential need to use orthogonal methods to assure the quality of therapeutic protein products. J Pharm Sci (2010) 1.16
Expression, limited proteolysis and preliminary crystallographic analysis of IpaD, a component of the Shigella flexneri type III secretion system. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 1.15
Structure-function analysis of invasion plasmid antigen C (IpaC) from Shigella flexneri. J Biol Chem (2002) 1.15
Phase I evaluation of delta virG Shigella sonnei live, attenuated, oral vaccine strain WRSS1 in healthy adults. Infect Immun (2002) 1.15
Evaluating Burkholderia pseudomallei Bip proteins as vaccines and Bip antibodies as detection agents. FEMS Immunol Med Microbiol (2007) 1.14
Ultrastructural analysis of IpaD at the tip of the nascent MxiH type III secretion apparatus of Shigella flexneri. J Mol Biol (2012) 1.12
Structural characterization of the N terminus of IpaC from Shigella flexneri. Infect Immun (2003) 1.12
Physical characterization of MxiH and PrgI, the needle component of the type III secretion apparatus from Shigella and Salmonella. Protein Sci (2006) 1.11
Conformational changes in IpaD from Shigella flexneri upon binding bile salts provide insight into the second step of type III secretion. Biochemistry (2010) 1.11
Conformational stability and differential structural analysis of LcrV, PcrV, BipD, and SipD from type III secretion systems. Protein Sci (2007) 1.10
Expression, purification, crystallization and preliminary crystallographic analysis of MxiH, a subunit of the Shigella flexneri type III secretion system needle. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 1.08
Properties of synthetic spider silk fibers based on Argiope aurantia MaSp2. Biomacromolecules (2008) 1.08
A rapid, three-step process for the preformulation of a recombinant ricin toxin A-chain vaccine. J Pharm Sci (2007) 1.06
Identification of the bile salt binding site on IpaD from Shigella flexneri and the influence of ligand binding on IpaD structure. Proteins (2012) 1.05
Anthrax vaccine powder formulations for nasal mucosal delivery. J Pharm Sci (2006) 1.04
Effect of metal cations on the conformation and inactivation of recombinant human factor VIII. J Pharm Sci (2004) 1.04
Identification of the MxiH needle protein residues responsible for anchoring invasion plasmid antigen D to the type III secretion needle tip. J Biol Chem (2007) 1.04
Influence of aggregation on immunogenicity of recombinant human Factor VIII in hemophilia A mice. J Pharm Sci (2006) 1.04
Characterization of a novel fusion protein from IpaB and IpaD of Shigella spp. and its potential as a pan-Shigella vaccine. Infect Immun (2013) 1.02
The complex inter-relationships between protein flexibility and stability. J Pharm Sci (2008) 1.02
The presence of a truncated base excision repair pathway in human spermatozoa that is mediated by OGG1. J Cell Sci (2013) 1.01
The structure of DNA within cationic lipid/DNA complexes. Biophys J (2003) 1.01
Identification of properties important to protein aggregation using feature selection. BMC Bioinformatics (2013) 1.00
Spectroscopic and calorimetric analyses of invasion plasmid antigen D (IpaD) from Shigella flexneri reveal the presence of two structural domains. Biochemistry (2006) 1.00
Effects of stabilizers on the destabilization of proteins upon adsorption to aluminum salt adjuvants. J Pharm Sci (2007) 1.00
Oligomeric states of the Shigella translocator protein IpaB provide structural insights into formation of the type III secretion translocon. Protein Sci (2013) 0.99
Binding affects the tertiary and quaternary structures of the Shigella translocator protein IpaB and its chaperone IpgC. Biochemistry (2012) 0.99
Effects of solutes on empirical phase diagrams of human fibroblast growth factor 1. J Pharm Sci (2007) 0.99
Insulin containing polyethylenimine-dextran sulfate nanoparticles. Int J Pharm (2003) 0.99
Characterization of the interaction of single tryptophan containing mutants of IpaC from Shigella flexneri with phospholipid membranes. Biochemistry (2006) 0.98
Multidimensional methods for the formulation of biopharmaceuticals and vaccines. J Pharm Sci (2011) 0.98
A novel scoring function for discriminating hyperthermophilic and mesophilic proteins with application to predicting relative thermostability of protein mutants. BMC Bioinformatics (2010) 0.98