Published in Cell on June 15, 2007
From cells to organs: building polarized tissue. Nat Rev Mol Cell Biol (2008) 5.06
Adherens junctions: from molecules to morphogenesis. Nat Rev Mol Cell Biol (2010) 3.97
Planar cell polarity signaling: from fly development to human disease. Annu Rev Genet (2008) 3.43
Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2. Dev Cell (2011) 3.12
Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat Cell Biol (2008) 3.07
Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells. Cell Stem Cell (2009) 3.02
Principles of planar polarity in animal development. Development (2011) 2.94
Vangl2 directs the posterior tilting and asymmetric localization of motile primary cilia. Nat Cell Biol (2010) 2.68
Asymmetric homotypic interactions of the atypical cadherin flamingo mediate intercellular polarity signaling. Cell (2008) 2.37
Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development. PLoS Genet (2008) 2.29
Planar cell polarity signaling: the developing cell's compass. Cold Spring Harb Perspect Biol (2009) 2.02
Rho-kinase directs Bazooka/Par-3 planar polarity during Drosophila axis elongation. Dev Cell (2010) 1.99
The PCP pathway instructs the planar orientation of ciliated cells in the Xenopus larval skin. Curr Biol (2009) 1.87
Planar polarization of node cells determines the rotational axis of node cilia. Nat Cell Biol (2010) 1.83
Cilia organize ependymal planar polarity. J Neurosci (2010) 1.80
Differential stability of flamingo protein complexes underlies the establishment of planar polarity. Curr Biol (2008) 1.78
A positional Toll receptor code directs convergent extension in Drosophila. Nature (2014) 1.77
Convergence and extension at gastrulation require a myosin IIB-dependent cortical actin network. Development (2008) 1.77
Opposing Wnt pathways orient cell polarity during organogenesis. Cell (2008) 1.70
Myosin-IXA regulates collective epithelial cell migration by targeting RhoGAP activity to cell-cell junctions. Curr Biol (2012) 1.70
Planar cell polarity: coordinating morphogenetic cell behaviors with embryonic polarity. Dev Cell (2011) 1.64
Atypical cadherins Dachsous and Fat control dynamics of noncentrosomal microtubules in planar cell polarity. Dev Cell (2010) 1.63
A quest for the mechanism regulating global planar cell polarity of tissues. Trends Cell Biol (2009) 1.60
Local auxin biosynthesis modulates gradient-directed planar polarity in Arabidopsis. Nat Cell Biol (2009) 1.59
Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem. J Neurosci (2010) 1.57
Bioelectric mechanisms in regeneration: Unique aspects and future perspectives. Semin Cell Dev Biol (2009) 1.56
Vangl2 promotes Wnt/planar cell polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidance. Dev Cell (2011) 1.56
The frizzled extracellular domain is a ligand for Van Gogh/Stbm during nonautonomous planar cell polarity signaling. Dev Cell (2008) 1.55
FoxJ1-dependent gene expression is required for differentiation of radial glia into ependymal cells and a subset of astrocytes in the postnatal brain. Development (2009) 1.55
Generation of diverse biological forms through combinatorial interactions between tissue polarity and growth. PLoS Comput Biol (2011) 1.48
Elaborating polarity: PAR proteins and the cytoskeleton. Development (2011) 1.40
A GRFa2/Prop1/stem (GPS) cell niche in the pituitary. PLoS One (2009) 1.31
Wg and Wnt4 provide long-range directional input to planar cell polarity orientation in Drosophila. Nat Cell Biol (2013) 1.31
Cadherin-based intercellular adhesions organize epithelial cell-matrix traction forces. Proc Natl Acad Sci U S A (2012) 1.31
Tropomodulin1 is required for membrane skeleton organization and hexagonal geometry of fiber cells in the mouse lens. J Cell Biol (2009) 1.30
Mouse prickle1, the homolog of a PCP gene, is essential for epiblast apical-basal polarity. Proc Natl Acad Sci U S A (2009) 1.29
Dynamics of core planar polarity protein turnover and stable assembly into discrete membrane subdomains. Dev Cell (2011) 1.28
Multicellular dynamics during epithelial elongation. Semin Cell Dev Biol (2008) 1.27
Epidermal wound repair is regulated by the planar cell polarity signaling pathway. Dev Cell (2010) 1.25
Cell intercalation from top to bottom. Nat Rev Mol Cell Biol (2014) 1.25
Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis. Development (2011) 1.24
Genetic control of organ shape and tissue polarity. PLoS Biol (2010) 1.23
Wnt signaling in development and disease. Cell Biosci (2012) 1.22
Wnt activity guides facial branchiomotor neuron migration, and involves the PCP pathway and JNK and ROCK kinases. Neural Dev (2009) 1.21
Latrophilin signaling links anterior-posterior tissue polarity and oriented cell divisions in the C. elegans embryo. Dev Cell (2009) 1.18
Rac1-dependent collective cell migration is required for specification of the anterior-posterior body axis of the mouse. PLoS Biol (2010) 1.17
Regulation of PCP by the Fat signaling pathway. Genes Dev (2013) 1.17
Loss of Dact1 disrupts planar cell polarity signaling by altering dishevelled activity and leads to posterior malformation in mice. J Biol Chem (2010) 1.17
The plane facts of PCP in the CNS. Neuron (2008) 1.17
Planar cell polarity: A bridge too far? Curr Biol (2008) 1.17
Cell polarity as a regulator of cancer cell behavior plasticity. Annu Rev Cell Dev Biol (2012) 1.15
Gradients and the specification of planar polarity in the insect cuticle. Cold Spring Harb Perspect Biol (2009) 1.14
Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation. Development (2008) 1.13
Do the protocadherins Fat and Dachsous link up to determine both planar cell polarity and the dimensions of organs? Nat Cell Biol (2008) 1.13
Planar cell polarity signaling: coordination of cellular orientation across tissues. Wiley Interdiscip Rev Dev Biol (2013) 1.11
The various roles of ubiquitin in Wnt pathway regulation. Cell Cycle (2010) 1.08
Disruption of PCP signaling causes limb morphogenesis and skeletal defects and may underlie Robinow syndrome and brachydactyly type B. Hum Mol Genet (2010) 1.07
Dissecting the molecular bridges that mediate the function of Frizzled in planar cell polarity. Development (2012) 1.07
Wnt signaling in mammalian development: lessons from mouse genetics. Cold Spring Harb Perspect Biol (2012) 1.06
H,K-ATPase protein localization and Kir4.1 function reveal concordance of three axes during early determination of left-right asymmetry. Mech Dev (2007) 1.05
Is left-right asymmetry a form of planar cell polarity? Development (2009) 1.04
Vimentin regulates scribble activity by protecting it from proteasomal degradation. Mol Biol Cell (2009) 1.04
The frizzled/stan pathway and planar cell polarity in the Drosophila wing. Curr Top Dev Biol (2012) 1.04
Centrosome positioning in vertebrate development. J Cell Sci (2012) 1.03
Wnt5b-Ryk pathway provides directional signals to regulate gastrulation movement. J Cell Biol (2010) 1.03
Planar cell polarity genes control the connectivity of enteric neurons. J Clin Invest (2013) 1.03
Expanding the morphogenetic repertoire: perspectives from the Drosophila egg. Dev Cell (2012) 1.02
Multi-cellular rosettes in the mouse visceral endoderm facilitate the ordered migration of anterior visceral endoderm cells. PLoS Biol (2012) 1.02
Serrano (sano) functions with the planar cell polarity genes to control tracheal tube length. PLoS Genet (2009) 1.01
Wnt/PCP proteins regulate stereotyped axon branch extension in Drosophila. Development (2012) 1.00
Wnt to build a tube: contributions of Wnt signaling to epithelial tubulogenesis. Dev Dyn (2010) 1.00
Rho1 has multiple functions in Drosophila wing planar polarity. Dev Biol (2009) 0.99
mrhl RNA, a long noncoding RNA, negatively regulates Wnt signaling through its protein partner Ddx5/p68 in mouse spermatogonial cells. Mol Cell Biol (2012) 0.99
Nonmuscle myosin II is required for cell proliferation, cell sheet adhesion and wing hair morphology during wing morphogenesis. Dev Biol (2010) 0.99
VANG-1 and PRKL-1 cooperate to negatively regulate neurite formation in Caenorhabditis elegans. PLoS Genet (2011) 0.98
Disruption of planar cell polarity activity leads to developmental biliary defects. Dev Biol (2011) 0.97
Regulation of cytoskeletal organization and junctional remodeling by the atypical cadherin Fat. Development (2013) 0.97
Disheveled mediated planar cell polarity signaling is required in the second heart field lineage for outflow tract morphogenesis. Dev Biol (2012) 0.96
Translating cell polarity into tissue elongation. Semin Cell Dev Biol (2011) 0.95
The Wnt/β-catenin pathway in human fibrotic-like diseases and its eligibility as a therapeutic target. Mol Cell Ther (2015) 0.94
A genome-wide screen reveals a role for microRNA-1 in modulating cardiac cell polarity. Dev Cell (2011) 0.93
Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear. Development (2012) 0.93
Coupling mechanical deformations and planar cell polarity to create regular patterns in the zebrafish retina. PLoS Comput Biol (2012) 0.93
La FAM fatale: USP9X in development and disease. Cell Mol Life Sci (2015) 0.92
Mink1 regulates β-catenin-independent Wnt signaling via Prickle phosphorylation. Mol Cell Biol (2011) 0.92
Dishevelled links basal body docking and orientation in ciliated epithelial cells. Trends Cell Biol (2008) 0.91
Regulation of basal body and ciliary functions by Diversin. Mech Dev (2011) 0.91
Formins in development: orchestrating body plan origami. Biochim Biophys Acta (2008) 0.91
Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis. Dev Biol (2012) 0.91
Rap1 maintains adhesion between cells to affect Egfr signaling and planar cell polarity in Drosophila. Dev Biol (2009) 0.90
Understanding epithelial homeostasis in the intestine: An old battlefield of ideas, recent breakthroughs and remaining controversies. Tissue Barriers (2013) 0.90
Modelling planar polarity of epithelia: the role of signal relay in collective cell polarization. J R Soc Interface (2011) 0.90
Left-right asymmetry in the chick embryo requires core planar cell polarity protein Vangl2. Genesis (2009) 0.90
Planar polarity: A new player in both lung development and disease. Organogenesis (2011) 0.90
Bbof1 is required to maintain cilia orientation. Development (2013) 0.89
The long and the short of Wnt signaling in C. elegans. Curr Opin Genet Dev (2008) 0.89
Cellular and molecular processes leading to embryo formation in sponges: evidences for high conservation of processes throughout animal evolution. Dev Genes Evol (2012) 0.89
Antagonistic functions of Dishevelleds regulate Frizzled3 endocytosis via filopodia tips in Wnt-mediated growth cone guidance. J Neurosci (2013) 0.88
The Drosophila selectin furrowed mediates intercellular planar cell polarity interactions via frizzled stabilization. Dev Cell (2013) 0.87
Collective epithelial and mesenchymal cell migration during gastrulation. Curr Genomics (2012) 0.87