Published in Cell Cycle on May 10, 2007
Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells. Science (2009) 2.76
Epigenetic mechanisms of regulation of Foxp3 expression. Blood (2009) 2.27
Immunomodulatory effects of deacetylase inhibitors: therapeutic targeting of FOXP3+ regulatory T cells. Nat Rev Drug Discov (2009) 2.00
TGF-beta and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3. Proc Natl Acad Sci U S A (2008) 1.65
Molecular orchestration of differentiation and function of regulatory T cells. Genes Dev (2009) 1.38
Structure of a domain-swapped FOXP3 dimer on DNA and its function in regulatory T cells. Immunity (2011) 1.23
Histone acetyltransferase mediated regulation of FOXP3 acetylation and Treg function. Curr Opin Immunol (2010) 1.23
Regulatory T cells: roles of T cell receptor for their development and function. Semin Immunopathol (2010) 1.02
Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease. Hum Mol Genet (2012) 0.96
Histone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancy. Genes Cancer (2015) 0.95
Dynamic interactions between TIP60 and p300 regulate FOXP3 function through a structural switch defined by a single lysine on TIP60. Cell Rep (2014) 0.91
Regulation of immune responses by histone deacetylase inhibitors. ISRN Hematol (2012) 0.90
Special regulatory T-cell review: FOXP3 biochemistry in regulatory T cells--how diverse signals regulate suppression. Immunology (2008) 0.86
Origin and functions of pro-inflammatory cytokine producing Foxp3+ regulatory T cells. Cytokine (2015) 0.85
The biology of FoxP3: a key player in immune suppression during infections, autoimmune diseases and cancer. Adv Exp Med Biol (2009) 0.85
The forkhead transcription factor, FOXP3, is required for normal pituitary gonadotropin expression in mice. Biol Reprod (2012) 0.83
Lysosome-dependent p300/FOXP3 degradation and limits Treg cell functions and enhances targeted therapy against cancers. Exp Mol Pathol (2013) 0.83
ChIP-on-chip analysis identifies IL-22 as direct target gene of ectopically expressed FOXP3 transcription factor in human T cells. BMC Genomics (2012) 0.80
Foxp3 regulates megakaryopoiesis and platelet function. Arterioscler Thromb Vasc Biol (2009) 0.79
Epigenetic enzymes are the therapeutic targets for CD4(+)CD25(+/high)Foxp3(+) regulatory T cells. Transl Res (2014) 0.78
Molecular and biological role of the FOXP3 N-terminal domain in immune regulation by T regulatory/suppressor cells. Exp Mol Pathol (2012) 0.78
Pim-2 Kinase Influences Regulatory T Cell Function and Stability by Mediating Foxp3 Protein N-terminal Phosphorylation. J Biol Chem (2015) 0.77
UXT is a novel regulatory factor of regulatory T cells associated with Foxp3. Eur J Immunol (2013) 0.77
The forkhead transcription factor, FOXP3: a critical role in male fertility in mice. Biol Reprod (2014) 0.76
FoxP3: A Key Player in T Regulatory Biology. Indian J Clin Biochem (2011) 0.75
Modulation of Treg function improves adenovirus vector-mediated gene expression in the airway. Gene Ther (2014) 0.75
Regulatory T Cell and Forkhead Box Protein 3 as Modulators of Immune Homeostasis. Front Immunol (2017) 0.75
Deacetylase inhibition promotes the generation and function of regulatory T cells. Nat Med (2007) 6.61
Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer. Nat Immunol (2007) 6.22
FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression. Proc Natl Acad Sci U S A (2007) 3.32
Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome. Immunity (2009) 2.84
ErbB receptors: from oncogenes to targeted cancer therapies. J Clin Invest (2007) 2.78
Immunomodulatory effects of deacetylase inhibitors: therapeutic targeting of FOXP3+ regulatory T cells. Nat Rev Drug Discov (2009) 2.00
CD147 immunoglobulin superfamily receptor function and role in pathology. Exp Mol Pathol (2007) 1.77
TGF-beta and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3. Proc Natl Acad Sci U S A (2008) 1.65
Common genetic variants and modification of penetrance of BRCA2-associated breast cancer. PLoS Genet (2010) 1.56
FOXP3 is a homo-oligomer and a component of a supramolecular regulatory complex disabled in the human XLAAD/IPEX autoimmune disease. Int Immunol (2007) 1.39
Characterization of the structures involved in localization of the SUN proteins to the nuclear envelope and the centrosome. DNA Cell Biol (2006) 1.26
Histone acetyltransferase mediated regulation of FOXP3 acetylation and Treg function. Curr Opin Immunol (2010) 1.23
Deacetylase inhibition increases regulatory T cell function and decreases incidence and severity of collagen-induced arthritis. Exp Mol Pathol (2009) 1.22
Structure of Sad1-UNC84 homology (SUN) domain defines features of molecular bridge in nuclear envelope. J Biol Chem (2011) 1.22
Disabling receptor ensembles with rationally designed interface peptidomimetics. J Biol Chem (2002) 1.21
The role of HER2 in early breast cancer metastasis and the origins of resistance to HER2-targeted therapies. Exp Mol Pathol (2009) 1.18
FOXP3 ensembles in T-cell regulation. Immunol Rev (2006) 1.15
Structural and biological features of FOXP3 dimerization relevant to regulatory T cell function. Cell Rep (2012) 1.14
FOXP3 and its partners: structural and biochemical insights into the regulation of FOXP3 activity. Immunol Res (2008) 1.10
Cep55/c10orf3, a tumor antigen derived from a centrosome residing protein in breast carcinoma. J Immunother (2009) 1.10
Polymersomes: a new multi-functional tool for cancer diagnosis and therapy. Methods (2008) 1.09
EGFR enhances Survivin expression through the phosphoinositide 3 (PI-3) kinase signaling pathway. Exp Mol Pathol (2005) 1.09
Immune regulation by histone deacetylases: a focus on the alteration of FOXP3 activity. Immunol Cell Biol (2011) 1.08
Structural insights into SUN-KASH complexes across the nuclear envelope. Cell Res (2012) 1.07
Ca(2+) and K(+) (BK) channels in chick hair cells are clustered and colocalized with apical-basal and tonotopic gradients. J Physiol (2004) 1.06
A sensitive and high-throughput assay to detect low-abundance proteins in serum. Nat Med (2006) 1.03
Fish otolith contains a unique structural protein, otolin-1. Eur J Biochem (2002) 1.01
The centrosome in normal and transformed cells. DNA Cell Biol (2004) 1.00
UXT is a novel centrosomal protein essential for cell viability. Mol Biol Cell (2005) 0.99
The feasibility of Cep55/c10orf3 derived peptide vaccine therapy for colorectal carcinoma. Exp Mol Pathol (2010) 0.99
Gefitinib-sensitive EGFR lacking residues 746-750 exhibits hypophosphorylation at tyrosine residue 1045, hypoubiquitination, and impaired endocytosis. DNA Cell Biol (2007) 0.98
Biochemistry and therapeutic implications of mechanisms involved in FOXP3 activity in immune suppression. Curr Opin Immunol (2007) 0.94
Human glucocorticoid-induced TNF receptor ligand regulates its signaling activity through multiple oligomerization states. Proc Natl Acad Sci U S A (2008) 0.94
The OPCML tumor suppressor functions as a cell surface repressor-adaptor, negatively regulating receptor tyrosine kinases in epithelial ovarian cancer. Cancer Discov (2012) 0.94
Structural and biochemical studies of RIG-I antiviral signaling. Protein Cell (2012) 0.93
Structural basis for ligand-mediated mouse GITR activation. Proc Natl Acad Sci U S A (2008) 0.92
Suppression of human prostate tumor growth by a unique prostate-specific monoclonal antibody F77 targeting a glycolipid marker. Proc Natl Acad Sci U S A (2009) 0.91
DIPA, which can localize to the centrosome, associates with p78/MCRS1/MSP58 and acts as a repressor of gene transcription. Exp Mol Pathol (2006) 0.90
Nek2 targets the mitotic checkpoint proteins Mad2 and Cdc20: a mechanism for aneuploidy in cancer. Exp Mol Pathol (2009) 0.90
Targeting erbB receptors. Semin Cell Dev Biol (2010) 0.90
Mechanisms of resistance to ErbB-targeted cancer therapeutics. J Clin Invest (2008) 0.90
FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3. J Clin Invest (2015) 0.89
Role of extracellular subdomains of p185c-neu and the epidermal growth factor receptor in ligand-independent association and transactivation. Proc Natl Acad Sci U S A (2003) 0.89
Histone deacetylase inhibitors and transplantation. Curr Opin Immunol (2007) 0.87
Special regulatory T-cell review: FOXP3 biochemistry in regulatory T cells--how diverse signals regulate suppression. Immunology (2008) 0.86
Disabling TNF receptor signaling by induced conformational perturbation of tryptophan-107. Proc Natl Acad Sci U S A (2005) 0.86
Structural insights into the down-regulation of overexpressed p185(her2/neu) protein of transformed cells by the antibody chA21. J Biol Chem (2011) 0.85
Expression and function of ErbB receptors and ligands in the pituitary. Endocr Relat Cancer (2011) 0.84
Targeted antireceptor therapy with monoclonal antibodies leads to the formation of inactivated tetrameric forms of ErbB receptors. J Immunol (2007) 0.84
Cooperative regulatory events and Foxp3 expression. Nat Immunol (2011) 0.84
Characterization of Su48, a centrosome protein essential for cell division. Proc Natl Acad Sci U S A (2006) 0.84
The TNF receptor superfamily: role in immune inflammation and bone formation. Immunol Res (2003) 0.83
Lysosome-dependent p300/FOXP3 degradation and limits Treg cell functions and enhances targeted therapy against cancers. Exp Mol Pathol (2013) 0.83
Sialylation regulates peripheral tolerance in CD4+ T cells. Int Immunol (2005) 0.83
Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population. Exp Mol Pathol (2011) 0.82
The gefitinib-sensitizing mutant epidermal growth factor receptor enables transformation of a mouse fibroblast cell line. DNA Cell Biol (2006) 0.82
Test for detection of disease-associated prion aggregate in the blood of infected but asymptomatic animals. Clin Vaccine Immunol (2006) 0.82
HER2/Neu: mechanisms of dimerization/oligomerization. Oncogene (2002) 0.81
Fas-disabling small exocyclic peptide mimetics limit apoptosis by an unexpected mechanism. Proc Natl Acad Sci U S A (2004) 0.81
Non-invasive, ultra-sensitive, high-throughput assays to quantify rare biomarkers in the blood. Methods (2008) 0.79
A structural modulator of tumor necrosis factor type 1 receptor promotes bone formation under lipopolysaccharide-induced inflammation in a murine tooth extraction model. Eur J Pharmacol (2012) 0.79
MDM2 regulates a novel form of incomplete neoplastic transformation of Theileria parva infected lymphocytes. Exp Mol Pathol (2012) 0.79
Molecular and biological role of the FOXP3 N-terminal domain in immune regulation by T regulatory/suppressor cells. Exp Mol Pathol (2012) 0.78
Mutations in K-Ras linked to levels of osteoprotegerin and sensitivity to TRAIL-induced cell death in pancreatic ductal adenocarcinoma cells. Exp Mol Pathol (2012) 0.78
Therapeutic monoclonal antibodies for the ErbB family of receptor tyrosine kinases. Cancer Biol Ther (2003) 0.78
Modulation of biomolecular interactions with complex-binding small molecules. Methods (2008) 0.78
Germinal center kinases in immune regulation. Cell Mol Immunol (2012) 0.78
Structural aspects of the FOXP3 regulatory complex as an immunopharmacological target. Int Immunopharmacol (2009) 0.77
Towards comprehensive characterization of HER2 overexpression. Mol Syst Biol (2006) 0.77
Structure-based approaches to inhibition of erbB receptors with peptide mimetics. Immunol Res (2003) 0.77
The extracellular domain of p185(c-neu) induces density-dependent inhibition of cell growth in malignant mesothelioma cells and reduces growth of mesothelioma in vivo. DNA Cell Biol (2006) 0.76
Differential localization of ErbB receptor ensembles influences their signaling in hippocampal neurons. DNA Cell Biol (2005) 0.76
Structure based antibody-like peptidomimetics. Pharmaceuticals (Basel) (2012) 0.76
Reversion of the ErbB malignant phenotype and the DNA damage response. Exp Mol Pathol (2012) 0.76
Development of anti-EGF receptor peptidomimetics (AERP) as tumor imaging agent. Bioorg Med Chem Lett (2011) 0.75
Trastuzumab in breast cancer. N Engl J Med (2006) 0.75
Regulation of the immune response. Curr Opin Immunol (2010) 0.75
Anergy and suppression as coexistent mechanisms for the maintenance of peripheral T cell tolerance. Immunol Res (2003) 0.75
FOXP3⁺ regulatory T cell development and function require histone/protein deacetylase 3. J Clin Invest (2015) 0.75
Methods. Guest editor's introduction. Methods (2008) 0.75
Mechanisms of peripheral immune tolerance: conversion of the immune to the unresponsive phenotype. Immunol Res (2003) 0.75
Characterization of mouse tGolgin-1 (golgin-245/trans-golgi p230/256 kD golgin) and its upregulation during oligodendrocyte development. DNA Cell Biol (2002) 0.75