Published in Trends Neurosci on June 29, 2007
Affective neuroscience of pleasure: reward in humans and animals. Psychopharmacology (Berl) (2008) 3.26
Disruption of NMDAR-dependent burst firing by dopamine neurons provides selective assessment of phasic dopamine-dependent behavior. Proc Natl Acad Sci U S A (2009) 3.15
Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding. Cell Metab (2009) 3.07
'Liking' and 'wanting' food rewards: brain substrates and roles in eating disorders. Physiol Behav (2009) 2.94
The tempted brain eats: pleasure and desire circuits in obesity and eating disorders. Brain Res (2010) 2.68
Apo-ghrelin receptor forms heteromers with DRD2 in hypothalamic neurons and is essential for anorexigenic effects of DRD2 agonism. Neuron (2012) 2.30
Dopamine, behavioral economics, and effort. Front Behav Neurosci (2009) 1.91
Genetical genomic determinants of alcohol consumption in rats and humans. BMC Biol (2009) 1.81
Mesolimbic dopamine in desire and dread: enabling motivation to be generated by localized glutamate disruptions in nucleus accumbens. J Neurosci (2008) 1.76
Insulin induces long-term depression of ventral tegmental area dopamine neurons via endocannabinoids. Nat Neurosci (2013) 1.73
Insulin in the ventral tegmental area reduces hedonic feeding and suppresses dopamine concentration via increased reuptake. Eur J Neurosci (2012) 1.66
Nigrostriatal rAAV-mediated GDNF overexpression induces robust weight loss in a rat model of age-related obesity. Mol Ther (2009) 1.52
The drive to eat: comparisons and distinctions between mechanisms of food reward and drug addiction. Nat Neurosci (2012) 1.33
Food restriction alters N'-propyl-4,5,6,7-tetrahydrobenzothiazole-2,6-diamine dihydrochloride (pramipexole)-induced yawning, hypothermia, and locomotor activity in rats: evidence for sensitization of dopamine D2 receptor-mediated effects. J Pharmacol Exp Ther (2008) 1.31
Enhanced hypothalamic leptin signaling in mice lacking dopamine D2 receptors. J Biol Chem (2010) 1.23
Reduced accumbens dopamine in Sprague-Dawley rats prone to overeating a fat-rich diet. Physiol Behav (2010) 1.22
Metabolic hormones, dopamine circuits, and feeding. Front Neuroendocrinol (2009) 1.22
Dopamine signaling in reward-related behaviors. Front Neural Circuits (2013) 1.21
Dopamine or opioid stimulation of nucleus accumbens similarly amplify cue-triggered 'wanting' for reward: entire core and medial shell mapped as substrates for PIT enhancement. Eur J Neurosci (2013) 1.19
The action of leptin in the ventral tegmental area to decrease food intake is dependent on Jak-2 signaling. Am J Physiol Endocrinol Metab (2009) 1.14
Regulation of fat intake in the absence of flavour signalling. J Physiol (2012) 1.14
Imaging of brain dopamine pathways: implications for understanding obesity. J Addict Med (2009) 1.14
Does the difference between physically active and couch potato lie in the dopamine system? Int J Biol Sci (2010) 1.08
High fat diet and food restriction differentially modify the behavioral effects of quinpirole and raclopride in rats. Eur J Pharmacol (2009) 1.07
Bromocriptine administration reduces hyperphagia and adiposity and differentially affects dopamine D2 receptor and transporter binding in leptin-receptor-deficient Zucker rats and rats with diet-induced obesity. Neuroendocrinology (2008) 1.05
You are what you eat: influence of type and amount of food consumed on central dopamine systems and the behavioral effects of direct- and indirect-acting dopamine receptor agonists. Neuropharmacology (2012) 1.04
Insulin signaling and addiction. Neuropharmacology (2011) 1.04
Influence of body weight and type of chow on the sensitivity of rats to the behavioral effects of the direct-acting dopamine-receptor agonist quinpirole. Psychopharmacology (Berl) (2011) 1.03
Neurodegeneration in an animal model of Parkinson's disease is exacerbated by a high-fat diet. Am J Physiol Regul Integr Comp Physiol (2010) 1.01
Impaired striatal Akt signaling disrupts dopamine homeostasis and increases feeding. PLoS One (2011) 1.01
Putting desire on a budget: dopamine and energy expenditure, reconciling reward and resources. Front Integr Neurosci (2012) 1.00
The effects of two highly selective dopamine D3 receptor antagonists (SB-277011A and NGB-2904) on food self-administration in a rodent model of obesity. Pharmacol Biochem Behav (2008) 1.00
The gut-brain dopamine axis: a regulatory system for caloric intake. Physiol Behav (2012) 0.98
Complementary roles of orexin and melanin-concentrating hormone in feeding behavior. Int J Endocrinol (2013) 0.97
Leptin increases striatal dopamine D2 receptor binding in leptin-deficient obese (ob/ob) mice. Synapse (2010) 0.97
Brain regulation of energy balance and body weight. Rev Endocr Metab Disord (2013) 0.96
The central GLP-1: implications for food and drug reward. Front Neurosci (2013) 0.96
Spinal leptin contributes to the pathogenesis of neuropathic pain in rodents. J Clin Invest (2009) 0.96
The dopamine D3 receptor partial agonist CJB 090 inhibits the discriminative stimulus but not the reinforcing or priming effects of cocaine in squirrel monkeys. Psychopharmacology (Berl) (2009) 0.96
Ventral striatum binding of a dopamine D2/3 receptor agonist but not antagonist predicts normal body mass index. Biol Psychiatry (2013) 0.96
Building a neuroscience of pleasure and well-being. Psychol Well Being (2011) 0.95
Leptin enhances NMDA-induced spinal excitation in rats: A functional link between adipocytokine and neuropathic pain. Pain (2011) 0.95
Dopamine signaling in food addiction: role of dopamine D2 receptors. BMB Rep (2013) 0.95
Stimulation of movement in a quiescent, hibernation-like form of Caenorhabditis elegans by dopamine signaling. J Neurosci (2009) 0.95
Stress induced obesity: lessons from rodent models of stress. Front Neurosci (2013) 0.93
Bidirectional modulation of substantia nigra activity by motivational state. PLoS One (2013) 0.92
Why does the giant panda eat bamboo? A comparative analysis of appetite-reward-related genes among mammals. PLoS One (2011) 0.89
Amphetamine alters behavior and mesocorticolimbic dopamine receptor expression in the monogamous female prairie vole. Brain Res (2010) 0.89
Obesity: pathophysiology and intervention. Nutrients (2014) 0.88
Rescue of dopamine transporter function in hypoinsulinemic rats by a D2 receptor-ERK-dependent mechanism. J Neurosci (2012) 0.88
Altered feeding and body weight following melanocortin administration to the ventral tegmental area in adult rats. Psychopharmacology (Berl) (2012) 0.88
Interactions between genotype and depressive symptoms on obesity. Behav Genet (2009) 0.87
Insulin regulation of monoamine signaling: pathway to obesity. Neuropsychopharmacology (2011) 0.87
Ghrelin signalling on food reward: a salient link between the gut and the mesolimbic system. J Neuroendocrinol (2015) 0.87
Striatal dopamine homeostasis is altered in mice following Roux-en-Y gastric bypass surgery. ACS Chem Neurosci (2014) 0.86
Catecholamines up integrates dopamine synthesis and synaptic trafficking. J Neurochem (2011) 0.85
Dopaminergic enhancement of local food-seeking is under global homeostatic control. Eur J Neurosci (2011) 0.85
Attention-deficit/hyperactivity disorder: is it time to reappraise the role of sugar consumption? Postgrad Med (2011) 0.84
Natural addiction: a behavioral and circuit model based on sugar addiction in rats. J Addict Med (2009) 0.84
Leptin influence in craving and relapse of alcoholics and smokers. J Clin Med Res (2013) 0.84
Acute high fat diet consumption activates the mesolimbic circuit and requires orexin signaling in a mouse model. PLoS One (2014) 0.84
Leptin and insulin signaling in dopaminergic neurons: relationship between energy balance and reward system. Front Psychol (2014) 0.84
Differential effects of chronic social stress and fluoxetine on meal patterns in mice. Appetite (2013) 0.84
Melanocortin 4 Receptor and Dopamine D2 Receptor Expression in Brain Areas Involved in Food Intake. Endocrinol Metab (Seoul) (2015) 0.84
Compensatory weight gain due to dopaminergic hypofunction: new evidence and own incidental observations. Nutr Metab (Lond) (2008) 0.83
Stimulation of dopamine D1 receptor improves learning capacity in cooperating cleaner fish. Proc Biol Sci (2016) 0.82
Mechanisms of body weight fluctuations in Parkinson's disease. Front Neurol (2014) 0.82
Effect of insulin on excitatory synaptic transmission onto dopamine neurons of the ventral tegmental area in a mouse model of hyperinsulinemia. Nutr Diabetes (2013) 0.82
Environmental exposure, obesity, and Parkinson's disease: lessons from fat and old worms. Environ Health Perspect (2010) 0.82
Epistatic interaction between COMT and DAT1 genes on eating behavior: a pilot study. Eat Behav (2009) 0.82
Considerations about rodent models of binge eating episodes. Front Psychol (2014) 0.81
Overeating Behavior and Striatal Dopamine with 6-[F]-Fluoro-L-m-Tyrosine PET. J Obes (2010) 0.81
Restricted access to standard or high fat chow alters sensitivity of rats to the 5-HT(2A/2C) receptor agonist 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane. Behav Pharmacol (2014) 0.81
Involvement of nucleus accumbens AMPA receptor trafficking in augmentation of D- amphetamine reward in food-restricted rats. Psychopharmacology (Berl) (2014) 0.81
Central Leptin Regulation of Obesity and Fertility. Curr Obes Rep (2012) 0.81
Central manipulation of dopamine receptors attenuates the orexigenic action of ghrelin. Psychopharmacology (Berl) (2013) 0.80
Dietary triglycerides act on mesolimbic structures to regulate the rewarding and motivational aspects of feeding. Mol Psychiatry (2014) 0.80
Degeneration of Dopaminergic Neurons Due to Metabolic Alterations and Parkinson's Disease. Front Aging Neurosci (2016) 0.79
Moving beyond energy homeostasis: new roles for glucagon-like peptide-1 in food and drug reward. Neurochem Int (2013) 0.79
Feeding and reward: ontogenetic changes in an animal model of obesity. Neuropharmacology (2012) 0.79
Decreased consumption of rewarding sucrose solutions after injection of melanocortins into the ventral tegmental area of rats. Psychopharmacology (Berl) (2014) 0.79
Hypothalamic arcuate nucleus tyrosine hydroxylase neurons play orexigenic role in energy homeostasis. Nat Neurosci (2016) 0.79
Dopamine D2/3 receptor antagonism reduces activity-based anorexia. Transl Psychiatry (2015) 0.78
Reduced insulin sensitivity is related to less endogenous dopamine at D2/3 receptors in the ventral striatum of healthy nonobese humans. Int J Neuropsychopharmacol (2015) 0.78
The anorexic agents, sibutramine and fenfluramine, depress GABA(B)-induced inhibitory postsynaptic potentials in rat mesencephalic dopaminergic cells. Br J Pharmacol (2009) 0.78
The role of leptin in antipsychotic-induced weight gain: genetic and non-genetic factors. J Obes (2012) 0.78
Association between rs9930506 polymorphism of the fat mass & obesity-associated (FTO) gene & onset of obesity in Polish adults. Indian J Med Res (2016) 0.78
Body Mass Index in Multiple Sclerosis: Associations with CSF Neurotransmitter Metabolite Levels. ISRN Neurol (2013) 0.78
Apo-Ghrelin Receptor (apo-GHSR1a) Regulates Dopamine Signaling in the Brain. Front Endocrinol (Lausanne) (2014) 0.78
Homeostatic reinforcement learning for integrating reward collection and physiological stability. Elife (2014) 0.78
Changes in circulating leptin levels during acute stress and associations with craving in abstinent smokers: a preliminary investigation. Psychoneuroendocrinology (2014) 0.77
Impaired mTORC2 signaling in catecholaminergic neurons exaggerates high fat diet-induced hyperphagia. Heliyon (2015) 0.77
Reduced insulin-receptor mediated modulation of striatal dopamine release by basal insulin as a possible contributing factor to hyperdopaminergia in schizophrenia. Med Hypotheses (2015) 0.77
Citicoline affects appetite and cortico-limbic responses to images of high-calorie foods. Int J Eat Disord (2010) 0.77
Episodic sucrose intake during food restriction increases synaptic abundance of AMPA receptors in nucleus accumbens and augments intake of sucrose following restoration of ad libitum feeding. Neuroscience (2015) 0.77
Novel pharmacologic treatment in acute binge eating disorder - role of lisdexamfetamine. Neuropsychiatr Dis Treat (2016) 0.77
Dietary chromium supplementation for targeted treatment of diabetes patients with comorbid depression and binge eating. Med Hypotheses (2015) 0.76
Dopamine signaling regulates fat content through β-oxidation in Caenorhabditis elegans. PLoS One (2014) 0.76
Atypical antipsychotics and effects on feeding: from mice to men. Psychopharmacology (Berl) (2016) 0.76