Published in Plant Cell Rep on July 03, 2007
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Molecular cloning and functional expression of codeinone reductase: the penultimate enzyme in morphine biosynthesis in the opium poppy Papaver somniferum. Plant J (1999) 1.28
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Molecular cloning and heterologous expression of a cDNA encoding berbamunine synthase, a C--O phenol-coupling cytochrome P450 from the higher plant Berberis stolonifera. Proc Natl Acad Sci U S A (1995) 1.23
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Expression of a chimeric farnesyl diphosphate synthase gene in Artemisia annua L. transgenic plants via Agrobacterium tumefaciens-mediated transformation. Plant Sci (2000) 1.22
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Genetic engineering of essential oil production in mint. Curr Opin Plant Biol (1999) 1.21
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Molecular cloning and characterization of CYP719, a methylenedioxy bridge-forming enzyme that belongs to a novel P450 family, from cultured Coptis japonica cells. J Biol Chem (2003) 1.21
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The final acylation step in taxol biosynthesis: cloning of the taxoid C13-side-chain N-benzoyltransferase from Taxus. Proc Natl Acad Sci U S A (2002) 1.19
Transgene organization in rice engineered through direct DNA transfer supports a two-phase integration mechanism mediated by the establishment of integration hot spots. Proc Natl Acad Sci U S A (1998) 1.17
Artemisinin and its derivatives: an important new class of antimalarial agents. Pharmacol Ther (2001) 1.14
Monoterpene double-bond reductases of the (-)-menthol biosynthetic pathway: isolation and characterization of cDNAs encoding (-)-isopiperitenone reductase and (+)-pulegone reductase of peppermint. Arch Biochem Biophys (2003) 1.14
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Molecular cloning and functional expression of O-methyltransferases common to isoquinoline alkaloid and phenylpropanoid biosynthesis. Plant J (1999) 1.11
Molecular cloning and characterization of coclaurine N-methyltransferase from cultured cells of Coptis japonica. J Biol Chem (2001) 1.10
Engineering tropane biosynthetic pathway in Hyoscyamus niger hairy root cultures. Proc Natl Acad Sci U S A (2004) 1.09
Monoterpene metabolism. Cloning, expression, and characterization of menthone reductases from peppermint. Plant Physiol (2005) 1.09
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EST database for early flower development in California poppy (Eschscholzia californica Cham., Papaveraceae) tags over 6,000 genes from a basal eudicot. Plant Mol Biol (2006) 1.07
Engineering the plant cell factory for secondary metabolite production. Transgenic Res (2000) 1.06
Monoterpene metabolism. Cloning, expression, and characterization of (-)-isopiperitenol/(-)-carveol dehydrogenase of peppermint and spearmint. Plant Physiol (2005) 1.05
A highly efficient in vitro plant regeneration system and Agrobacterium-mediated transformation in Plumbago zeylanica. Plant Cell Rep (2006) 1.05
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Metabolic engineering of the chloroplast genome using the Echerichia coli ubiC gene reveals that chorismate is a readily abundant plant precursor for p-hydroxybenzoic acid biosynthesis. Plant Physiol (2004) 1.04
A role for intra- and intercellular translocation in natural product biosynthesis. Curr Opin Plant Biol (2005) 1.03
The roles of latex and the vascular bundle in morphine biosynthesis in the opium poppy, Papaver somniferum. Proc Natl Acad Sci U S A (2004) 1.02
Increasing morphinan alkaloid production by over-expressing codeinone reductase in transgenic Papaver somniferum. Plant Biotechnol J (2007) 1.01
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Molecular cloning and heterologous expression of the C-13 phenylpropanoid side chain-CoA acyltransferase that functions in Taxol biosynthesis. Proc Natl Acad Sci U S A (2002) 1.00
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Increased production of cadaverine and anabasine in hairy root cultures of Nicotiana tabacum expressing a bacterial lysine decarboxylase gene. Plant Mol Biol (1993) 0.96
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Antisense-mediated down-regulation of putrescine N-methyltransferase activity in transgenic Nicotiana tabacum L. can lead to elevated levels of anatabine at the expense of nicotine. Plant Mol Biol (2003) 0.96
Cloning and analysis of a cDNA encoding farnesyl diphosphate synthase from Artemisia annua. Gene (1996) 0.95
Methyl jasmonate induced production of taxol in suspension cultures of Taxus cuspidata: ethylene interaction and induction models. Biotechnol Prog (1996) 0.95
Naturally derived anti-HIV agents. Phytother Res (2005) 0.93
Metabolic engineering of cell cultures versus whole plant complexity in production of bioactive monoterpene indole alkaloids: recent progress related to old dilemma. J Biosci Bioeng (2006) 0.92
Expression profiling of genes involved in paclitaxel biosynthesis for targeted metabolic engineering. Metab Eng (2006) 0.92
Knockdown of berberine bridge enzyme by RNAi accumulates (S)-reticuline and activates a silent pathway in cultured California poppy cells. Transgenic Res (2006) 0.92
New genes in alkaloid metabolism and transport. Curr Opin Biotechnol (2003) 0.92
Transformation of opium poppy (Papaver somniferum L.) with antisense berberine bridge enzyme gene (anti-bbe) via somatic embryogenesis results in an altered ratio of alkaloids in latex but not in roots. Transgenic Res (2004) 0.92
Increased and altered fragrance of tobacco plants after metabolic engineering using three monoterpene synthases from lemon. Plant Physiol (2004) 0.91
Expression of two consecutive genes of a secondary metabolic pathway in transgenic tobacco: molecular diversity influences levels of expression and product accumulation. Plant Mol Biol (1998) 0.91
Molecular cloning of columbamine O-methyltransferase from cultured Coptis japonica cells. Eur J Biochem (2002) 0.91
Enhanced secretion of tropane alkaloids in Nicotiana tabacum hairy roots expressing heterologous hyoscyamine-6beta-hydroxylase. J Exp Bot (2005) 0.91
Metabolic engineering of the indole pathway in Catharanthus roseus hairy roots and increased accumulation of tryptamine and serpentine. Metab Eng (2004) 0.91
Bacillus thuringiensis: a century of research, development and commercial applications. Plant Biotechnol J (2011) 3.04
The production of recombinant pharmaceutical proteins in plants. Nat Rev Genet (2003) 2.11
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Modulation of the polyamine biosynthetic pathway in transgenic rice confers tolerance to drought stress. Proc Natl Acad Sci U S A (2004) 1.67
EU legitimizes GM crop exclusion zones. Nat Biotechnol (2011) 1.63
Plant-based production of biopharmaceuticals. Curr Opin Plant Biol (2004) 1.60
Molecular farming for new drugs and vaccines. Current perspectives on the production of pharmaceuticals in transgenic plants. EMBO Rep (2005) 1.45
Recent developments and future prospects in insect pest control in transgenic crops. Trends Plant Sci (2006) 1.40
Combinatorial genetic transformation generates a library of metabolic phenotypes for the carotenoid pathway in maize. Proc Natl Acad Sci U S A (2008) 1.39
Trace and traceability--a call for regulatory harmony. Nat Biotechnol (2008) 1.35
Transgenic multivitamin corn through biofortification of endosperm with three vitamins representing three distinct metabolic pathways. Proc Natl Acad Sci U S A (2009) 1.26
Sowing the seeds of success: pharmaceutical proteins from plants. Curr Opin Biotechnol (2005) 1.26
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Cost-effective production of a vaginal protein microbicide to prevent HIV transmission. Proc Natl Acad Sci U S A (2008) 1.23
Unexpected deposition patterns of recombinant proteins in post-endoplasmic reticulum compartments of wheat endosperm. Plant Physiol (2004) 1.22
Endosperm-specific co-expression of recombinant soybean ferritin and Aspergillus phytase in maize results in significant increases in the levels of bioavailable iron. Plant Mol Biol (2005) 1.17
When more is better: multigene engineering in plants. Trends Plant Sci (2009) 1.17
Transgenic strategies for the nutritional enhancement of plants. Trends Plant Sci (2007) 1.10
EU-OSTID: a collection of transposon insertional mutants for functional genomics in rice. Plant Mol Biol (2005) 1.08
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An alternative strategy for sustainable pest resistance in genetically enhanced crops. Proc Natl Acad Sci U S A (2005) 1.03
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Introns are key regulatory elements of rice tubulin expression. Planta (2003) 0.98
Nutritious crops producing multiple carotenoids--a metabolic balancing act. Trends Plant Sci (2011) 0.97
The intracellular fate of a recombinant protein is tissue dependent. Plant Physiol (2006) 0.96
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The regulation of carotenoid pigmentation in flowers. Arch Biochem Biophys (2010) 0.95
A recombinant multimeric immunoglobulin expressed in rice shows assembly-dependent subcellular localization in endosperm cells. Plant Biotechnol J (2005) 0.93
Promoter diversity in multigene transformation. Plant Mol Biol (2010) 0.93
Constitutive expression of a barley Fe phytosiderophore transporter increases alkaline soil tolerance and results in iron partitioning between vegetative and storage tissues under stress. Plant Physiol Biochem (2012) 0.93
Cloning and functional characterization of the maize carotenoid isomerase and β-carotene hydroxylase genes and their regulation during endosperm maturation. Transgenic Res (2010) 0.92
Expression of a heterologous S-adenosylmethionine decarboxylase cDNA in plants demonstrates that changes in S-adenosyl-L-methionine decarboxylase activity determine levels of the higher polyamines spermidine and spermine. Plant Physiol (2002) 0.91
An in vitro system for the rapid functional characterization of genes involved in carotenoid biosynthesis and accumulation. Plant J (2014) 0.90
Plurality of opinion, scientific discourse and pseudoscience: an in depth analysis of the Séralini et al. study claiming that Roundup™ Ready corn or the herbicide Roundup™ cause cancer in rats. Transgenic Res (2013) 0.90
Realising the value of plant molecular pharming to benefit the poor in developing countries and emerging economies. Plant Biotechnol J (2013) 0.90
Spermine facilitates recovery from drought but does not confer drought tolerance in transgenic rice plants expressing Datura stramonium S-adenosylmethionine decarboxylase. Plant Mol Biol (2009) 0.89
The contribution of transgenic plants to better health through improved nutrition: opportunities and constraints. Genes Nutr (2012) 0.88
Biofortification of plants with altered antioxidant content and composition: genetic engineering strategies. Plant Biotechnol J (2012) 0.87
Synergistic metabolism in hybrid corn indicates bottlenecks in the carotenoid pathway and leads to the accumulation of extraordinary levels of the nutritionally important carotenoid zeaxanthin. Plant Biotechnol J (2010) 0.84
Deletion of the C-terminal 138 amino acids of the wheat FKBP73 abrogates calmodulin binding, dimerization and male fertility in transgenic rice. Plant Mol Biol (2002) 0.84
High-value products from transgenic maize. Biotechnol Adv (2010) 0.83
Engineering complex metabolic pathways in plants. Annu Rev Plant Biol (2014) 0.83
Antibody production in transgenic plants. Methods Mol Biol (2004) 0.83
Ascorbic acid synthesis and metabolism in maize are subject to complex and genotype-dependent feedback regulation during endosperm development. Biotechnol J (2013) 0.82
Metabolic engineering of ketocarotenoid biosynthesis in higher plants. Arch Biochem Biophys (2008) 0.82
Plant cells as pharmaceutical factories. Curr Pharm Des (2013) 0.81
Identification of carotenoids using mass spectrometry. Mass Spectrom Rev (2013) 0.81
Targeted transcriptomic and metabolic profiling reveals temporal bottlenecks in the maize carotenoid pathway that may be addressed by multigene engineering. Plant J (2013) 0.81
The humanitarian impact of plant biotechnology: recent breakthroughs vs bottlenecks for adoption. Curr Opin Plant Biol (2010) 0.81
Fast quantitative method for the analysis of carotenoids in transgenic maize. J Agric Food Chem (2013) 0.80
Field trials and tribulations--making sense of the regulations for experimental field trials of transgenic crops in Europe. Plant Biotechnol J (2012) 0.80
Mice fed on a diet enriched with genetically engineered multivitamin corn show no sub-acute toxic effects and no sub-chronic toxicity. Plant Biotechnol J (2012) 0.80
Simultaneous expression of Arabidopsis ρ-hydroxyphenylpyruvate dioxygenase and MPBQ methyltransferase in transgenic corn kernels triples the tocopherol content. Transgenic Res (2010) 0.80
Can the world afford to ignore biotechnology solutions that address food insecurity? Plant Mol Biol (2013) 0.79